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Home > Products >  China Biggest Factory & Manufacturer supply R-Alpha-Lipoic Acid (R-ALA) 500MT/Year

China Biggest Factory & Manufacturer supply R-Alpha-Lipoic Acid (R-ALA) 500MT/Year CAS NO.1200-22-2

  • FOB Price: USD: 1.00-2.00 /Kilogram Get Latest Price
  • Min.Order: 100 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,MoneyGram,Other
  • Available Specifications:

    AAAAA(50-100)KilogramAAAAA(100-500)Kilogram

  • Product Details

Keywords

  • R-(+)-Alpha-Lipoic Acid
  • 1200-22-2
  • R-ALA

Quick Details

  • ProName: China Biggest Factory & Manufacturer s...
  • CasNo: 1200-22-2
  • Molecular Formula: 1200-22-2
  • Appearance: white powder
  • Application: Pharm chemicals industry
  • DeliveryTime: 3-5 days
  • PackAge: 25KG/Drum
  • Port: Shanghai Guangzhou Qingdao Shenzhen
  • ProductionCapacity: 20 Metric Ton/Month
  • Purity: 99%
  • Storage: 2-8°C
  • Transportation: By air /Sea/ coruier
  • LimitNum: 100 Kilogram
  • Heavy Metal: 1
  • Limited Quantity: 1
  • Valid Period: 2
  • Color: Red
  • Melting point: ≥350°C
  • Boiling point: 363.24°C (rough estimate)
  • density: 1.667
  • solubility: 1 M NaOH: 10 mg/mL, dark green
  • Water Solubility: <0.1 g/100 mL at 21 oC
  • Stability: Stable. Combustible. Incompatible with...

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

Details

(R)-(+)-1,2-Dithiolane-3-pentanoic acid Basic information
Product Name: (R)-(+)-1,2-Dithiolane-3-pentanoic acid
Synonyms: 5-[(3R)-1,2-dithiolan-3-yl]pentanoic acid;5-[(3R)-dithiolan-3-yl]pentanoic acid;5-[(3R)-dithiolan-3-yl]valeric acid;(R)-(+)-1,2-Dithiola;(R)-5-(1,2-Dithiolan-3-yl)pentanoic acid;(R)-Thioctic Acid (R)-1,2-Dithiolane-3-valeric Acid;D-lipoic acid;(R)-(+)-1,2-Dithiolane-3-pentanoic acid 97%
CAS: 1200-22-2
MF: C8H14O2S2
MW: 206.33
EINECS: 638-752-2
Product Categories: API;Sulfur & Selenium Compounds;Chiral Reagents;Chiral Building Blocks;Heterocyclic Building Blocks;Others;FINE Chemical & INTERMEDIATES;Heterocycles
Mol File: 1200-22-2.mol
(R)-(+)-1,2-Dithiolane-3-pentanoic acid Structure
 
(R)-(+)-1,2-Dithiolane-3-pentanoic acid Chemical Properties
Melting point  48-52 °C(lit.)
alpha  D23 +104° (c = 0.88 in benzene)
Boiling point  185-195 °C(Press: 0.5 Torr)
density  1.218±0.06 g/cm3(Predicted)
refractive index  114 ° (C=1, EtOH)
Fp  >230 °F
storage temp.  -20°C
solubility  Acetonitrile (Slightly), Chloroform (Slightly), DMSO
pka 5.4(at 25℃)
form  Solid
color  Light Yellow to Yellow Low-Melting
optical activity [α]20/D +104°, c = 1 in chloroform
Merck  14,9326
CAS DataBase Reference 1200-22-2(CAS DataBase Reference)
 
Safety Information
Risk Statements  22-36/38
Safety Statements  20-36-26-35
WGK Germany  3
HS Code  29349990
MSDS Information
Provider Language
SigmaAldrich English
 
(R)-(+)-1,2-Dithiolane-3-pentanoic acid Usage And Synthesis
Chemical Properties Yellow Crystalline Solid
Uses A fat-metabolism stimulator
Uses

α-Lipoic acid has been used as a reference standard for the analysis of α-lipoic acid in human plasma by high performance liquid chromatography coupled to electron capture detector (HPLC-ECD), in various food matrices and dietary supplements by HPLC combined with coulometric electrode array detector (CEAD) as well as electrospray ionization mass spectrometer (ESI-MS).
It may be used as a reference standard for the determination of α-lipoic acid in human urine by isocratic reversed-phase HPLC and in α-lipoic acid capsules by HPLC with chemiluminescence detection.

General Description

α-Lipoic acid is an antioxidant which is generally present in plants, animals and many other microorganisms.

Biochem/physiol Actions (R)-(+)-α-Lipoic acid was shown to significantly increase pyruvate oxidation while abrogating fatty acid oxidation in rat hepatocytes. These effects make R-(+)-α-Lipoic acid a promising treatment option for the treatment of Type II diabetes. It is a biological antioxidant with prooxidant activities, its therapeutic potential is widely investigated, e.g. in the treatment for Alzheimer′s disease.
 
(R)-(+)-1,2-Dithiolane-3-pentanoic acid Preparation Products And Raw materials
Preparation Products DIHYDROLIPOIC ACID

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