China Biggest Factory manufacturer supply 3-HYDROXYBUTYRIC ACID SODIUM SALT(BHB Na) CAS NO.150-83-4

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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DL-3-Hydroxybutyric acid sodium salt Basic information Product Name: DL-3-Hydroxybutyric acid sodium salt Synonyms: (+/-)-3-HYDROXYBUTYRIC ACID SODIUM SALT;3-HYDROXYBUTYRIC ACID SODIUM SALT;DL-B-HYDROXYBUTYRIC ACID SODIUM*CRYSTALL INE;B-HydroxybutyricAcidSodiumSalt;Butanoic acid, 3-hydroxy-, monosodium salt;dl-β-hydroxybutyric acid sodium salt;DL-B-HYDROXYBUTYRICACIDSODIUMSALT;Sodium 3-hydroxyburyrate CAS: 150-83-4 MF: C4H7NaO3 MW: 126.09 EINECS: 205-774-5 Product Categories: Aliphatics Mol File: 150-83-4.mol   DL-3-Hydroxybutyric acid sodium salt Chemical Properties Melting point  167-170 °C storage temp.  2-8°C solubility  Methanol (Slightly, Sonicated), Water (Slightly) form  Crystalline Powder color  White Sensitive  Hygroscopic BRN  4824866 Stability: Hygroscopic InChIKey NBPUSGBJDWCHKC-UHFFFAOYSA-M CAS DataBase Reference 150-83-4(CAS DataBase Reference)   Safety Information Safety Statements  24/25 WGK Germany  3 RTECS  205-774-5 F  3-10 HS Code  29181990 MSDS Information Provider Language SigmaAldrich English ACROS English ALFA English   DL-3-Hydroxybutyric acid sodium salt Usage And Synthesis Chemical Properties white crystalline powder Uses Optically active 3-hydroxybutyric acids are key intermediates of the biosynthesis and metabolism of fatty acids and exist widely in biological systems. Uses (±)-Sodium 3-hydroxybutyrate has been used in a study to understand the effect of butyrate on fibroblast growth factor 21 (FGF21), which is involved in fatty acid -oxidation in liver. It may be used in the preparation of poly(3-hydroxybutyrate). Application DL-β-Hydroxybutyric acid sodium salt has been used: as a standard for quantifying blood plasma and milk β-hydroxybutyric acid in Danish Jersey cows. to investigate its anticonvulsant effects in epilepsy induced rats. to induce hyperketonemia in Holstein dairy cows. Definition ChEBI: An organic sodium salt resulting from the replacement of the proton from the carboxy group of 3-hydroxybutyric acid by a sodium ion. Biological Functions Neuroprotective compound in experimental models of neurodegenerative diseases. Shown to be oxidized as an energetic substrate in the brain during starvation. May inhibit brain glucose oxidation, which may account for the suppression of hepatic glucose production observed after administration of ketone bodies in humans. Biological Activity β-Hydroxybutyric acid is a ketone body present in the rumen epithelium of liver cells. Its interconversion to acetoacetate influences the acid-base balance and is coupled NADH generation from (nicotinamide adenine dinucleotide) NAD+, measured fluorimetrically. A high plasma level of β-hydroxybutyric acid is implicated in diabetic ketoacidosis. It traverses the blood-brain barrier as a monocarboxylic acid. β-Hydroxybutyric acid may play a protective role in dopaminergic neurodegeneration in Parkinson′s disease model. β-Hydroxybutyric acid is a ligand for G protein-coupled receptor(GPR109A) and favors inhibition of secretion, transcription and translation of growth hormone (GH) and prolactin (PRL) gene in cow anterior pituitary cells (DCAPCs). Biochem/physiol Actions β-Hydroxybutyric acid is a ketone body present in the rumen epithelium of liver cells. Its interconversion to acetoacetate influences the acid-base balance and is coupled NADH generation from (nicotinamide adenine dinucleotide) NAD+, measured fluorimetrically. A high plasma level of β-hydroxybutyric acid is implicated in diabetic ketoacidosis. It traverses the blood-brain barrier as a monocarboxylic acid. β-Hydroxybutyric acid may play a protective role in dopaminergic neurodegeneration in Parkinson′s disease model. β-Hydroxybutyric acid is a ligand for G protein-coupled receptor(GPR109A) and favors inhibition of secretion, transcription and translation of growth hormone (GH) and prolactin (PRL) gene in cow anterior pituitary cells (DCAPCs).   DL-3-Hydroxybutyric acid sodium salt Preparation Products And Raw materials Raw materials Sodium hydroxide-->Hydrochloric acid-->Ethyl acetate-->Methanol-->Potassium hydroxide-->Sodium borohydride-->Methyl acetoacetate-->Crotonic acid