China Largest Manufacturer factory sales D(+)-Galactosamine hydrochloride CAS 1772-03-8 CAS NO.1772-03-8

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D(+)-Galactosamine hydrochloride Basic information Product Name: D(+)-Galactosamine hydrochloride Synonyms: D-GALACTOSAMINE HYDROCHLORIDE extrapure;2-Amino-2-deoxy-D-galactopyranose hydrochloride, D-Chondrosamine hydrochloride, Chondrosamine;(2R,3R,4R,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride;D(+)-Galactosamine hydrochloride,99%;D-Glactosamine Hydrochloride;D-Galactosamine hydrochloride ,97%;D(+)-Galactosamine h;D-Galactosamine hydrochloride ,98.5% CAS: 1772-03-8 MF: C6H14ClNO5 MW: 215.63 EINECS: 217-198-1 Product Categories: Dextrins、Sugar & Carbohydrates;aldehydes;Sugars, Carbohydrates & Glucosides;Carbohydrates;13C & 2H Sugars;Carbohydrates & Derivatives;Aminosugars;Biochemistry;Galactose;Sugars;amino Mol File: 1772-03-8.mol   D(+)-Galactosamine hydrochloride Chemical Properties Melting point  182-185 °C (dec.)(lit.) alpha  96 º (589nm c=1,H2O,24 hrs) density  1.3965 (rough estimate) refractive index  96 ° (C=1, H2O) storage temp.  room temp solubility  H2O: 50 mg/mL, clear, colorless form  White solid color  White to Off-White Water Solubility  SOLUBLE Sensitive  Hygroscopic Merck  14,4334 BRN  3697825 Stability: Moisture Sensitive CAS DataBase Reference 1772-03-8(CAS DataBase Reference) EPA Substance Registry System D-Galactose, 2-amino-2-deoxy-, hydrochloride (1772-03-8)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  24/25-36/37/39-27-26 WGK Germany  3 RTECS  LW5500000 F  3-10 TSCA  Yes HS Code  29329970 MSDS Information Provider Language 2-Amino-2-deoxy-D-galactose hydrochloride English ACROS English SigmaAldrich English ALFA English   D(+)-Galactosamine hydrochloride Usage And Synthesis Chemical Properties White Crystalline Solid Uses Specifically inhibits COX-2 by preventing COX-2 N-glycosylation and by increasing COX-2 protein turnover in a proteasome-dependent manner. Uses D-(+)-Galactosamine (D-chondrosamine) is used with lipopolysaccharides (LPS) to induce models of acute hepatic failure (LPS/D-GalN-induced liver injury, hepatitis) for therapeutic research to find new drugs. Uses D-(+)-Galactosamine hydrochloride has been used to: induce livery injury inflammatory liver injury acute liver failure (ALF) in mice General Description Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards Biochem/physiol Actions Galactosamine (D-GalN) is synthesized from galactose and is potential hepatotoxic agent. D-GalN in combination with lipopolysaccharide leads to the development of lethal liver injury and hepatic failure. It sensitizes cells to the toxic effects of the cytokine in particular the tumor necrosis factor(TNF). Purification Methods Dissolve the hydrochloride in a small volume of H2O. Then add three volumes of EtOH, followed by acetone until faintly turbid and keep overnight in a refrigerator. [Roseman & Ludoweig J Am Chem Soc 76 301 1954, Beilstein 4 IV 2024.]   D(+)-Galactosamine hydrochloride Preparation Products And Raw materials

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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D(+)-Galactosamine hydrochloride Basic information Product Name: D(+)-Galactosamine hydrochloride Synonyms: D-GALACTOSAMINE HYDROCHLORIDE extrapure;2-Amino-2-deoxy-D-galactopyranose hydrochloride, D-Chondrosamine hydrochloride, Chondrosamine;(2R,3R,4R,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride;D(+)-Galactosamine hydrochloride,99%;D-Glactosamine Hydrochloride;D-Galactosamine hydrochloride ,97%;D(+)-Galactosamine h;D-Galactosamine hydrochloride ,98.5% CAS: 1772-03-8 MF: C6H14ClNO5 MW: 215.63 EINECS: 217-198-1 Product Categories: Dextrins、Sugar & Carbohydrates;aldehydes;Sugars, Carbohydrates & Glucosides;Carbohydrates;13C & 2H Sugars;Carbohydrates & Derivatives;Aminosugars;Biochemistry;Galactose;Sugars;amino Mol File: 1772-03-8.mol   D(+)-Galactosamine hydrochloride Chemical Properties Melting point  182-185 °C (dec.)(lit.) alpha  96 º (589nm c=1,H2O,24 hrs) density  1.3965 (rough estimate) refractive index  96 ° (C=1, H2O) storage temp.  room temp solubility  H2O: 50 mg/mL, clear, colorless form  White solid color  White to Off-White Water Solubility  SOLUBLE Sensitive  Hygroscopic Merck  14,4334 BRN  3697825 Stability: Moisture Sensitive CAS DataBase Reference 1772-03-8(CAS DataBase Reference) EPA Substance Registry System D-Galactose, 2-amino-2-deoxy-, hydrochloride (1772-03-8)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  24/25-36/37/39-27-26 WGK Germany  3 RTECS  LW5500000 F  3-10 TSCA  Yes HS Code  29329970 MSDS Information Provider Language 2-Amino-2-deoxy-D-galactose hydrochloride English ACROS English SigmaAldrich English ALFA English   D(+)-Galactosamine hydrochloride Usage And Synthesis Chemical Properties White Crystalline Solid Uses Specifically inhibits COX-2 by preventing COX-2 N-glycosylation and by increasing COX-2 protein turnover in a proteasome-dependent manner. Uses D-(+)-Galactosamine (D-chondrosamine) is used with lipopolysaccharides (LPS) to induce models of acute hepatic failure (LPS/D-GalN-induced liver injury, hepatitis) for therapeutic research to find new drugs. Uses D-(+)-Galactosamine hydrochloride has been used to: induce livery injury inflammatory liver injury acute liver failure (ALF) in mice General Description Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards Biochem/physiol Actions Galactosamine (D-GalN) is synthesized from galactose and is potential hepatotoxic agent. D-GalN in combination with lipopolysaccharide leads to the development of lethal liver injury and hepatic failure. It sensitizes cells to the toxic effects of the cytokine in particular the tumor necrosis factor(TNF). Purification Methods Dissolve the hydrochloride in a small volume of H2O. Then add three volumes of EtOH, followed by acetone until faintly turbid and keep overnight in a refrigerator. [Roseman & Ludoweig J Am Chem Soc 76 301 1954, Beilstein 4 IV 2024.]   D(+)-Galactosamine hydrochloride Preparation Products And Raw materials