China Largest Manufacturer factory sales N-Acetyl-L-Methionine CAS 65-82-7 CAS NO.65-82-7

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N-Acetyl-L-methionine Basic information Identification Test Content Analysis Toxicity Grade Acute Toxicity Use Quantity Product Name: N-Acetyl-L-methionine Synonyms: N-ACETYL-L-METHIONINE:AC-MET-OH;(2S)-N-ACETYL-L-METHIONINE;N-Acetylmethionine;Ac-L-Met-OH;N-alpha-Actetyl-L-methionine;N-Acetyl-L-methionine >99%;N-Acetyl-L-methionine (NAM), 98.5%;N-ACETYL-L-MET CAS: 65-82-7 MF: C7H13NO3S MW: 191.25 EINECS: 200-617-7 Product Categories: Amino Acids;Amino Acid Derivatives;Methionine [Met, M];Ac-Amino Acids;Amino Acids (N-Protected);amino;Biochemistry;Pharmaceutical Intermediates;Amino Acid Derivatives;Methionine;Peptide Synthesis;99%min Mol File: 65-82-7.mol   N-Acetyl-L-methionine Chemical Properties Melting point  103-106 °C(lit.) alpha  -20 º (c=4 H2O) Boiling point  235 °C(Press: 12 Torr) density  1.2684 (rough estimate) refractive index  -21 ° (C=1, H2O) storage temp.  Sealed in dry,Room Temperature solubility  methanol: soluble100mg/mL, clear, colorless pka 3.50±0.10(Predicted) form  Solid color  White to Off-White optical activity [α]20/D -21.0±1.0°, c = 1% in H2O Merck  14,96 BRN  1725552 Stability: Stable. Incompatible with strong oxidizing agents. InChIKey XUYPXLNMDZIRQH-LURJTMIESA-N CAS DataBase Reference 65-82-7(CAS DataBase Reference) NIST Chemistry Reference N-acetylmethionine(65-82-7) EPA Substance Registry System L-Methionine, N-acetyl- (65-82-7)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  24/25-36-26 WGK Germany  3 RTECS  PD0480000 TSCA  Yes HazardClass  IRRITANT HS Code  29309070 MSDS Information Provider Language N-Acetyl-L-methionine English SigmaAldrich English ACROS English ALFA English   N-Acetyl-L-methionine Usage And Synthesis Identification Test Take a sample of 250mg, get it dissolved it in 2.5ml isopropyl alcohol and get it diluted with water to 25ml. Take this liquid of 10ml and get it diluted with water to 100m1. Then take the liquid of 0.5,30 and 50μ1 after two dilutions. Drop it at the place with a distance of 2cm from the bottom edge of the thin-layer chromatographic plate. The plate is coated with silica gel (Namely, 20cm * 20cm Brinkman silica gel of 60.250nm, or the equivalent). In a sealed and balanced thin-layered chromatography expansion tank, The chromatography was splayed out by 10cm, and the developer was composed of n-butanol and the mixture of acetic acid and water in the proportion 75：20=20. Dry the plate overnight. Then spray the chromatography plate with a new iodoplatinate solution mixed with 10 percent chloroplatinic acid of 3ml, water of 97ml and 6 percent potassium iodide solution of 100ml. The sample shall be formed - a separate color spot with a Rf value of 0.67~0.1 Content Analysis Weigh accurately about 250mg sample and put it in a flask with glass stopper. Add 100ml water, 5g dipotassium hydrogen phosphate, 2g potassium dihydrogen phosphate and 2g potassium iodide. Get it fully mixed and dissolved, plus 0. 1mol/L iodine solution of 50.0m1. Then stopper it and blend it. Leave it stand for 30 minutes and titrate excess iodine with 0.1mol / L sodium thiosulfate. Meanwhile conduct blank titration experiment. Iodine solution per Ml 0.1mol/L equals to this product (C7H13NO3S) 9.563mg. Toxicity Grade Safe for food(FDA，§172．372，2000). Acute Toxicity Vein - mouse LD50: 435 mg / kg Use Quantity Account for 3.1% of the total protein content in food (Calculated by free L- methionine). It shall not be used for infant food and food containing adding nitrite / nitrate (FDA, 172.3722000). Chemical Properties white crystals Uses N-Acetyl-L-methionine (CAS# 65-82-7) has been useful in the study of metabolic phenotypes of standard and cold- stored platelets. Definition ChEBI: An L-methionine derivative that is L-methionine in which one of the amine hydrogens is substituted by an acetyl group. Safety Profile Poison by intravenous route. When heated to decomposition emits toxic fumes of NOX,. Purification Methods Crystallise N-acetyl-L-methionine from Me2CO, H2O or EtOAc. Dry it in a vacuum over P2O5. Its solubility at 25o in H2O is 30.7%, and in Me2CO it is 29.5%. [Mitzi & Schueter Biochim Biophys Acta 27 168 1958, Birnbaum et al. J Biol Chem 194 455 1952, Beilstein 4 IV 3206.]   N-Acetyl-L-methionine Preparation Products And Raw materials Raw materials L-Methionine

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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N-Acetyl-L-methionine Basic information Identification Test Content Analysis Toxicity Grade Acute Toxicity Use Quantity Product Name: N-Acetyl-L-methionine Synonyms: N-ACETYL-L-METHIONINE:AC-MET-OH;(2S)-N-ACETYL-L-METHIONINE;N-Acetylmethionine;Ac-L-Met-OH;N-alpha-Actetyl-L-methionine;N-Acetyl-L-methionine >99%;N-Acetyl-L-methionine (NAM), 98.5%;N-ACETYL-L-MET CAS: 65-82-7 MF: C7H13NO3S MW: 191.25 EINECS: 200-617-7 Product Categories: Amino Acids;Amino Acid Derivatives;Methionine [Met, M];Ac-Amino Acids;Amino Acids (N-Protected);amino;Biochemistry;Pharmaceutical Intermediates;Amino Acid Derivatives;Methionine;Peptide Synthesis;99%min Mol File: 65-82-7.mol   N-Acetyl-L-methionine Chemical Properties Melting point  103-106 °C(lit.) alpha  -20 º (c=4 H2O) Boiling point  235 °C(Press: 12 Torr) density  1.2684 (rough estimate) refractive index  -21 ° (C=1, H2O) storage temp.  Sealed in dry,Room Temperature solubility  methanol: soluble100mg/mL, clear, colorless pka 3.50±0.10(Predicted) form  Solid color  White to Off-White optical activity [α]20/D -21.0±1.0°, c = 1% in H2O Merck  14,96 BRN  1725552 Stability: Stable. Incompatible with strong oxidizing agents. InChIKey XUYPXLNMDZIRQH-LURJTMIESA-N CAS DataBase Reference 65-82-7(CAS DataBase Reference) NIST Chemistry Reference N-acetylmethionine(65-82-7) EPA Substance Registry System L-Methionine, N-acetyl- (65-82-7)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  24/25-36-26 WGK Germany  3 RTECS  PD0480000 TSCA  Yes HazardClass  IRRITANT HS Code  29309070 MSDS Information Provider Language N-Acetyl-L-methionine English SigmaAldrich English ACROS English ALFA English   N-Acetyl-L-methionine Usage And Synthesis Identification Test Take a sample of 250mg, get it dissolved it in 2.5ml isopropyl alcohol and get it diluted with water to 25ml. Take this liquid of 10ml and get it diluted with water to 100m1. Then take the liquid of 0.5,30 and 50μ1 after two dilutions. Drop it at the place with a distance of 2cm from the bottom edge of the thin-layer chromatographic plate. The plate is coated with silica gel (Namely, 20cm * 20cm Brinkman silica gel of 60.250nm, or the equivalent). In a sealed and balanced thin-layered chromatography expansion tank, The chromatography was splayed out by 10cm, and the developer was composed of n-butanol and the mixture of acetic acid and water in the proportion 75：20=20. Dry the plate overnight. Then spray the chromatography plate with a new iodoplatinate solution mixed with 10 percent chloroplatinic acid of 3ml, water of 97ml and 6 percent potassium iodide solution of 100ml. The sample shall be formed - a separate color spot with a Rf value of 0.67~0.1 Content Analysis Weigh accurately about 250mg sample and put it in a flask with glass stopper. Add 100ml water, 5g dipotassium hydrogen phosphate, 2g potassium dihydrogen phosphate and 2g potassium iodide. Get it fully mixed and dissolved, plus 0. 1mol/L iodine solution of 50.0m1. Then stopper it and blend it. Leave it stand for 30 minutes and titrate excess iodine with 0.1mol / L sodium thiosulfate. Meanwhile conduct blank titration experiment. Iodine solution per Ml 0.1mol/L equals to this product (C7H13NO3S) 9.563mg. Toxicity Grade Safe for food(FDA，§172．372，2000). Acute Toxicity Vein - mouse LD50: 435 mg / kg Use Quantity Account for 3.1% of the total protein content in food (Calculated by free L- methionine). It shall not be used for infant food and food containing adding nitrite / nitrate (FDA, 172.3722000). Chemical Properties white crystals Uses N-Acetyl-L-methionine (CAS# 65-82-7) has been useful in the study of metabolic phenotypes of standard and cold- stored platelets. Definition ChEBI: An L-methionine derivative that is L-methionine in which one of the amine hydrogens is substituted by an acetyl group. Safety Profile Poison by intravenous route. When heated to decomposition emits toxic fumes of NOX,. Purification Methods Crystallise N-acetyl-L-methionine from Me2CO, H2O or EtOAc. Dry it in a vacuum over P2O5. Its solubility at 25o in H2O is 30.7%, and in Me2CO it is 29.5%. [Mitzi & Schueter Biochim Biophys Acta 27 168 1958, Birnbaum et al. J Biol Chem 194 455 1952, Beilstein 4 IV 3206.]   N-Acetyl-L-methionine Preparation Products And Raw materials Raw materials L-Methionine