China Largest Manufacturer factory sales 6-Chloropurine CAS 87-42-3 CAS NO.87-42-3

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6-Chloropurine Basic information Product Name: 6-Chloropurine Synonyms: 6-CHLOROPURINE 98.5+%;6-CHLOROPURINE extrapure;6-CHLOROPURINE (6ClP);9H-Purine, 6-chloro-;6-Chloropurine, 99+% 5GR;6-chloro-5H-purine;1H-Purine, 6-chloro-;6-chloro-1h-purin CAS: 87-42-3 MF: C5H3ClN4 MW: 154.56 EINECS: 201-745-6 Product Categories: Building Blocks;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;Biochemicals and Reagents;Nucleosides;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;PurinesHeterocyclic Building Blocks;NucleosidesHeterocyclic Building Blocks;Biochemicals and Reagents;Nucleosides, Nucleotides, Oligonucleotides;Oligonucleotides;FINE Chemical & INTERMEDIATES;Heterocyclic Compounds;Nucleotides and Nucleosides;Purines;Biochemistry;Nucleobases and their analogs;Nucleosides, Nucleotides & Related Reagents;Nucleic acids;Bases & Related Reagents;Nucleotides;Intermediates & Fine Chemicals;Pharmaceuticals Mol File: 87-42-3.mol   6-Chloropurine Chemical Properties Melting point  >300 °C (dec.) (lit.) Boiling point  254.17°C (rough estimate) density  1.4649 (rough estimate) refractive index  1.8430 (estimate) storage temp.  Keep in dark place,Sealed in dry,Room Temperature solubility  5 g/L form  crystalline pka 7.47±0.20(Predicted) color  yellow-orange Water Solubility  5 g/L Merck  14,2161 BRN  5774 InChIKey ZKBQDFAWXLTYKS-UHFFFAOYSA-N CAS DataBase Reference 87-42-3(CAS DataBase Reference) NIST Chemistry Reference 6-Chloropurine(87-42-3)   Safety Information Hazard Codes  Xn,Xi Risk Statements  22-36/37/38-20/21/22 Safety Statements  26-36-36/37/39 WGK Germany  3 RTECS  UO7520000 F  10-23 HazardClass  IRRITANT HS Code  29335990 Toxicity LD50 oral in mouse: 720mg/kg MSDS Information Provider Language 6-Chloropurine English ACROS English SigmaAldrich English ALFA English   6-Chloropurine Usage And Synthesis Chemical Properties White crystals Uses 6-Chloropurine is used in the preparation of 9-alkylpurines through alkylation with various substituted alkyl halides in dimethyl sulfoxide. It is also used to prepare 6-succinoaminopurine. Uses 6-Chloropurine has been used in the preparation of: 9-alkylpurines via alkylation with various substituted alkyl halides in DMSO 6-succinoaminopurine Synthesis Reference(s) Journal of the American Chemical Society, 78, p. 1928, 1956 DOI: 10.1021/ja01590a043 General Description The acid-catalyzed reaction of 6-chloropurine with 3,4-di-O-acetyl-D-xylal has been investigated. Purification Methods 6-Chloropurine crystallises from water. The UV in water at pH 1 has 264nm (log 3.94). [Beilstein 26 III/IV 1742.]   6-Chloropurine Preparation Products And Raw materials Preparation Products Adenine-->6-benzylaminopurine-->6-CYANOPURINE-->6-BENZYLOXYPURINE-->6-Dimethylaminopurine-->6-ETHYLMERCAPTOPURINE-->6-Mercaptopurine monohydrate-->6-N-BUTOXYPURINE-->6-Iodopurine-->6-Chloropurine ribonucleoside-->6-ETHOXYPURINE-->N-Benzyl-9-(tetrahydro-2H-pyran-2-yl)adenine-->6-CHLORO-7-METHYLPURINE

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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6-Chloropurine Basic information Product Name: 6-Chloropurine Synonyms: 6-CHLOROPURINE 98.5+%;6-CHLOROPURINE extrapure;6-CHLOROPURINE (6ClP);9H-Purine, 6-chloro-;6-Chloropurine, 99+% 5GR;6-chloro-5H-purine;1H-Purine, 6-chloro-;6-chloro-1h-purin CAS: 87-42-3 MF: C5H3ClN4 MW: 154.56 EINECS: 201-745-6 Product Categories: Building Blocks;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;Biochemicals and Reagents;Nucleosides;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;PurinesHeterocyclic Building Blocks;NucleosidesHeterocyclic Building Blocks;Biochemicals and Reagents;Nucleosides, Nucleotides, Oligonucleotides;Oligonucleotides;FINE Chemical & INTERMEDIATES;Heterocyclic Compounds;Nucleotides and Nucleosides;Purines;Biochemistry;Nucleobases and their analogs;Nucleosides, Nucleotides & Related Reagents;Nucleic acids;Bases & Related Reagents;Nucleotides;Intermediates & Fine Chemicals;Pharmaceuticals Mol File: 87-42-3.mol   6-Chloropurine Chemical Properties Melting point  >300 °C (dec.) (lit.) Boiling point  254.17°C (rough estimate) density  1.4649 (rough estimate) refractive index  1.8430 (estimate) storage temp.  Keep in dark place,Sealed in dry,Room Temperature solubility  5 g/L form  crystalline pka 7.47±0.20(Predicted) color  yellow-orange Water Solubility  5 g/L Merck  14,2161 BRN  5774 InChIKey ZKBQDFAWXLTYKS-UHFFFAOYSA-N CAS DataBase Reference 87-42-3(CAS DataBase Reference) NIST Chemistry Reference 6-Chloropurine(87-42-3)   Safety Information Hazard Codes  Xn,Xi Risk Statements  22-36/37/38-20/21/22 Safety Statements  26-36-36/37/39 WGK Germany  3 RTECS  UO7520000 F  10-23 HazardClass  IRRITANT HS Code  29335990 Toxicity LD50 oral in mouse: 720mg/kg MSDS Information Provider Language 6-Chloropurine English ACROS English SigmaAldrich English ALFA English   6-Chloropurine Usage And Synthesis Chemical Properties White crystals Uses 6-Chloropurine is used in the preparation of 9-alkylpurines through alkylation with various substituted alkyl halides in dimethyl sulfoxide. It is also used to prepare 6-succinoaminopurine. Uses 6-Chloropurine has been used in the preparation of: 9-alkylpurines via alkylation with various substituted alkyl halides in DMSO 6-succinoaminopurine Synthesis Reference(s) Journal of the American Chemical Society, 78, p. 1928, 1956 DOI: 10.1021/ja01590a043 General Description The acid-catalyzed reaction of 6-chloropurine with 3,4-di-O-acetyl-D-xylal has been investigated. Purification Methods 6-Chloropurine crystallises from water. The UV in water at pH 1 has 264nm (log 3.94). [Beilstein 26 III/IV 1742.]   6-Chloropurine Preparation Products And Raw materials Preparation Products Adenine-->6-benzylaminopurine-->6-CYANOPURINE-->6-BENZYLOXYPURINE-->6-Dimethylaminopurine-->6-ETHYLMERCAPTOPURINE-->6-Mercaptopurine monohydrate-->6-N-BUTOXYPURINE-->6-Iodopurine-->6-Chloropurine ribonucleoside-->6-ETHOXYPURINE-->N-Benzyl-9-(tetrahydro-2H-pyran-2-yl)adenine-->6-CHLORO-7-METHYLPURINE