China Largest Manufacturer factory sales USP, BP, EP, CP Dextrin CAS 9004-53-9 CAS NO.9004-53-9

                                PRODUCT DETAILS     

Cas No. 9004-53-9   H.S. Code 35051000

Main Purpose: Tablet binders and fillers.

Package: 25kg/kraft bag

Packing Size: 1.7cbm/mt

G.W. 25.2kg

Dextrin Basic information Identification test Toxicity Usage limit Chemical properties Application Production Product Name: Dextrin Synonyms: DEXTRIN HYDRATE;DEXTRIN N-HYDRATE;DEXTRIN FROM POTATO STARCH, FOR MICROBIO LOGY;DEXTRIN TYPE IV FROM POTATO;DEXTRIN FROM POTATO STARCH, FOR BIO-TECH N. PURPOSES;DEXTRIN TYPE III FROM CORN;DextrineWhite;Dextrin, precipitated by alcohol CAS: 9004-53-9 MF: C18H32O16 MW: 504.43708 EINECS: 232-675-4 Product Categories: Carbohydrates;Carbohydrates A to;Carbohydrate Extracts;Carbohydrates D-FBiochemicals and Reagents;Polysaccharide;Sugars for Media;Base Ingredients;Carbohydrate Sources (Sugars/Extracts) Mol File: 9004-53-9.mol   Dextrin Chemical Properties Melting point  53.75-54 °C density  0.8 g/cm3 storage temp.  Store at RT. solubility  H2O: 0.1 g/mL hot, complete, yellow to very deep yellow form  powder color  yellow Water Solubility  Soluble in hot water (0.1 g/ml). Sensitive  Hygroscopic Merck  14,2953 Stability: Stable. Combustible. Incompatible with strong oxidizing agents. InChIKey FYGDTMLNYKFZSV-MRCIVHHJSA-N EPA Substance Registry System Dextrin (9004-53-9)   Safety Information Safety Statements  24/25 WGK Germany  1 RTECS  HH9450000 F  3 TSCA  Yes HS Code  35051000 MSDS Information Provider Language Dextrin English   Dextrin Usage And Synthesis Identification test Take about 1 g sample and suspend it in 20ml of water. Add a few drops of iodine test solution (TS-124), which should then appear dark blue color to reddish brown color. The infrared absorption spectrum should be consistent with Figure 10107. Toxicity ADI does not make special provisions (FAO/WHO, 2001). GRAS (FDA, § 184.1277, 2000); Usage limit FAO/WHO (1984, g/kg): for broth, soup, the value should be according to GMI; cheese (in the cream mixture): 5; the sweetened yogurt and its products after being subject to the heat treatment: 10; mackerel and fish canned: 60 (Only in the packaging material); cold drink: 30. Chemical properties It appears as white, yellow or brown flowing powder. Dextrin of relatively small molecular weight is completely soluble in water to form viscous slurry; dextrin with relatively large molecular mass is not completely soluble in water. ADI is not subject to special provisions (FAO/WHO, 1994). Application It can be used as emulsifying stabilizers and thickeners, adhesives and surface decorators. It can be applied to the pharmaceutical industry, protective adhesives and suspending agents, adhesives. For example, it can be applied to the sizing treatment of paper, textile sizing and ink preparation; it can also be used as a drug excipient and a substitute of the Arabic gum. Production It is obtained from using natural starch originated from cereals or rhizome plants (E.g., corn, sorghum, potato, bamboo, wheat, rice, cassava, sago, etc.) as raw materials which are heated in the presence of suitable food-grade acids and buffers, leading to partial hydrolysis to obtain it. Drying method: apply hydrochloric acid (≤ 0.15%) or orthophosphoric acid (≤ 0.17%) treatment. Enzymatic method: take the natural starch of corn, wheat and dried potato as raw material, use 0.15% hydrochloric acid or 0.17% phosphoric acid for heat treatment, and apply starch partial degradation to derive the products. Chemical Properties White powder Chemical Properties Dextrin is partially hydrolyzed maize (corn), potato or cassava starch. It is a white, pale yellow or brown-colored powder with a slight characteristic odor. Uses Dextrin is a partially hydrolyzed starch formed from the treatment of starch by dry heat, acid, or enzymes. it can be formed from amylose and amylopectin-type starches. they are white or yellow (canary) in color. as compared to unmodified starch, s have increased water solubility, viscosity stability, and reduced paste viscosity. uses include dough improvement and binding. Uses Pharmaceutic aid (suspending agent); pharmaceutic aid (viscosity-increasing agent); pharmaceutic aid (tablet binder); pharmaceutic aid (tablet and capsule diluent). Uses dextrin (British gum; starch gum) absorbs moisture. It is also used as a binder to control product viscosity and reduce the density of a cosmetic. This powder is produced from corn starch and modified by means of a bacterial process. It may cause an allergic reaction. Production Methods Dextrin is prepared by the incomplete hydrolysis of starch by heating in the dry state with or without the aid ofsuitable acids and buffers; moisture may be added during heating. The PhEur 6.4 specifies that dextrin is derived from maize(corn),potatoorcassava starch. A specification for cassava is included in the USP32–NF27. Definition A polysaccharide sugar produced by the action of amylase enzymes on or the chemical hydrolysis of starch. Dextrins are used as adhesives. Definition dextrin: An intermediate polysaccharidecompound resulting fromthe hydrolysis of starch to maltose byamylase enzymes. General Description Dextrin is basically a sweet sugar extracted from potato starch. Dextrin color range is from white to tan; it has low to high solubilities in cold water, and gives pastes that vary widely in viscosity. It is produced from all commercial grain and tuber starches. During its manufacture, the factors taken into consideration are type of starch and moisture content, roasting time and temperature, and the type and amount of catalyst used. Agricultural Uses Dextrin is a group of colloidal products, formed by the hydrolysis of starches with dilute acids or by heating dry starch. The yellow or white powder or granules obtained are soluble in boiling water and insoluble in ether or alcohol. Dextrin is used in adhesives, as thickening agents and in penicillin manufacture. Pharmaceutical Applications Dextrin is a dextrose polymer used as an adhesive and stiffening agent for surgical dressings. It is also used as a tablet and capsule diluent; as a binder for tablet granulation; as a sugar-coating ingredient that serves as a plasticizer and adhesive; and as a thickening agent for suspensions. Additionally, dextrin has been used as a source of carbohydrate by people with special dietary requirements because it has a low electrolyte content and is free of lactose and sucrose. Dextrin is also used in cosmetics. Safety Profile Mdly toxic by intravenous route. When heated to decomposition it emits acrid smoke and irritating fumes. Safety Dextrin is generally regarded as a nontoxic and nonirritant material at the levels employed as an excipient. Larger quantities are used as a dietary supplement without adverse effects, although ingestion of very large quantities may be harmful. LD50 (mouse, IV): 0.35g/kg storage Physical characteristics of dextrin may vary slightly depending on the method of manufacture and on the source material. In aqueous solutions, dextrin molecules tend to aggregate as density, temperature, pH, or other characteristics change. An increase in viscosity is caused by gel at ion or retro gradation as dextrin solutions age,and is particularly noticeable in the less-soluble maize starch dextrins. Dextrin solutions are thixotropic, becoming less viscous when sheared but changing to a soft paste or gel when allowed to stand. However, acids that are present in dextrin as residues from manufacturing can cause further hydrolysis, which results in a gradual thinning of solutions. Residual acid, often found in lesssoluble dextrins such as pyrodextrin, will also cause a reduction in viscosity during dry storage. To eliminate these problems, dextrin manufacturers neutralize dextrins of low solubility with ammonia or sodium carbonate in the cooling vessel. The bulk material should be stored in a well-closed container in a cool, dry place. Incompatibilities Incompatible with strong oxidizing agents. Regulatory Status GRAS listed.Included in the FDA Inactive Ingredients Database(IV injections, oral tablets and topical preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.   Dextrin Preparation Products And Raw materials Raw materials Phosphoric acid Preparation Products SPINOSAD-->1H-as-Indaceno3,2-doxacyclododecin-7,15-dione, 2-(6-deoxy-2,3,4-tri-O-methyl-.alpha.-L-mannopyranosyl)oxy-13-(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yloxy-9-ethyl-2,3,3a,5a,5b,6,9,10,11,12,13,14,16a,16b-tetradecahydro-4,14-dimethyl-, (2-->CARAMEL-->D-(+)-Maltose monohydrate-->Oxytetracycline-->Cyclooctapentylose-->BETA-CYCLODEXTRIN-->BILE SALTS-->α-Amylase-->4-Bromobiphenyl-->chlorophyllin copper complex sodium salt-->D-Cycloserine-->Antifreeze-->Glucosyl licorice-->C.I.Basic Blue 26-->SAFFLOWER YELLOW-->Cyclohexapentylose-->Clavulanic acid-->compound nutrient-->Laminaria, ext.

                                                              About US 
Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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                                                       Product information

Cas No. 9004-53-9   H.S. Code 35051000

Main Purpose: Tablet binders and fillers.

Package: 25kg/kraft bag

Packing Size: 1.7cbm/mt

G.W. 25.2kg

Dextrin Basic information Identification test Toxicity Usage limit Chemical properties Application Production Product Name: Dextrin Synonyms: DEXTRIN HYDRATE;DEXTRIN N-HYDRATE;DEXTRIN FROM POTATO STARCH, FOR MICROBIO LOGY;DEXTRIN TYPE IV FROM POTATO;DEXTRIN FROM POTATO STARCH, FOR BIO-TECH N. PURPOSES;DEXTRIN TYPE III FROM CORN;DextrineWhite;Dextrin, precipitated by alcohol CAS: 9004-53-9 MF: C18H32O16 MW: 504.43708 EINECS: 232-675-4 Product Categories: Carbohydrates;Carbohydrates A to;Carbohydrate Extracts;Carbohydrates D-FBiochemicals and Reagents;Polysaccharide;Sugars for Media;Base Ingredients;Carbohydrate Sources (Sugars/Extracts) Mol File: 9004-53-9.mol   Dextrin Chemical Properties Melting point  53.75-54 °C density  0.8 g/cm3 storage temp.  Store at RT. solubility  H2O: 0.1 g/mL hot, complete, yellow to very deep yellow form  powder color  yellow Water Solubility  Soluble in hot water (0.1 g/ml). Sensitive  Hygroscopic Merck  14,2953 Stability: Stable. Combustible. Incompatible with strong oxidizing agents. InChIKey FYGDTMLNYKFZSV-MRCIVHHJSA-N EPA Substance Registry System Dextrin (9004-53-9)   Safety Information Safety Statements  24/25 WGK Germany  1 RTECS  HH9450000 F  3 TSCA  Yes HS Code  35051000 MSDS Information Provider Language Dextrin English   Dextrin Usage And Synthesis Identification test Take about 1 g sample and suspend it in 20ml of water. Add a few drops of iodine test solution (TS-124), which should then appear dark blue color to reddish brown color. The infrared absorption spectrum should be consistent with Figure 10107. Toxicity ADI does not make special provisions (FAO/WHO, 2001). GRAS (FDA, § 184.1277, 2000); Usage limit FAO/WHO (1984, g/kg): for broth, soup, the value should be according to GMI; cheese (in the cream mixture): 5; the sweetened yogurt and its products after being subject to the heat treatment: 10; mackerel and fish canned: 60 (Only in the packaging material); cold drink: 30. Chemical properties It appears as white, yellow or brown flowing powder. Dextrin of relatively small molecular weight is completely soluble in water to form viscous slurry; dextrin with relatively large molecular mass is not completely soluble in water. ADI is not subject to special provisions (FAO/WHO, 1994). Application It can be used as emulsifying stabilizers and thickeners, adhesives and surface decorators. It can be applied to the pharmaceutical industry, protective adhesives and suspending agents, adhesives. For example, it can be applied to the sizing treatment of paper, textile sizing and ink preparation; it can also be used as a drug excipient and a substitute of the Arabic gum. Production It is obtained from using natural starch originated from cereals or rhizome plants (E.g., corn, sorghum, potato, bamboo, wheat, rice, cassava, sago, etc.) as raw materials which are heated in the presence of suitable food-grade acids and buffers, leading to partial hydrolysis to obtain it. Drying method: apply hydrochloric acid (≤ 0.15%) or orthophosphoric acid (≤ 0.17%) treatment. Enzymatic method: take the natural starch of corn, wheat and dried potato as raw material, use 0.15% hydrochloric acid or 0.17% phosphoric acid for heat treatment, and apply starch partial degradation to derive the products. Chemical Properties White powder Chemical Properties Dextrin is partially hydrolyzed maize (corn), potato or cassava starch. It is a white, pale yellow or brown-colored powder with a slight characteristic odor. Uses Dextrin is a partially hydrolyzed starch formed from the treatment of starch by dry heat, acid, or enzymes. it can be formed from amylose and amylopectin-type starches. they are white or yellow (canary) in color. as compared to unmodified starch, s have increased water solubility, viscosity stability, and reduced paste viscosity. uses include dough improvement and binding. Uses Pharmaceutic aid (suspending agent); pharmaceutic aid (viscosity-increasing agent); pharmaceutic aid (tablet binder); pharmaceutic aid (tablet and capsule diluent). Uses dextrin (British gum; starch gum) absorbs moisture. It is also used as a binder to control product viscosity and reduce the density of a cosmetic. This powder is produced from corn starch and modified by means of a bacterial process. It may cause an allergic reaction. Production Methods Dextrin is prepared by the incomplete hydrolysis of starch by heating in the dry state with or without the aid ofsuitable acids and buffers; moisture may be added during heating. The PhEur 6.4 specifies that dextrin is derived from maize(corn),potatoorcassava starch. A specification for cassava is included in the USP32–NF27. Definition A polysaccharide sugar produced by the action of amylase enzymes on or the chemical hydrolysis of starch. Dextrins are used as adhesives. Definition dextrin: An intermediate polysaccharidecompound resulting fromthe hydrolysis of starch to maltose byamylase enzymes. General Description Dextrin is basically a sweet sugar extracted from potato starch. Dextrin color range is from white to tan; it has low to high solubilities in cold water, and gives pastes that vary widely in viscosity. It is produced from all commercial grain and tuber starches. During its manufacture, the factors taken into consideration are type of starch and moisture content, roasting time and temperature, and the type and amount of catalyst used. Agricultural Uses Dextrin is a group of colloidal products, formed by the hydrolysis of starches with dilute acids or by heating dry starch. The yellow or white powder or granules obtained are soluble in boiling water and insoluble in ether or alcohol. Dextrin is used in adhesives, as thickening agents and in penicillin manufacture. Pharmaceutical Applications Dextrin is a dextrose polymer used as an adhesive and stiffening agent for surgical dressings. It is also used as a tablet and capsule diluent; as a binder for tablet granulation; as a sugar-coating ingredient that serves as a plasticizer and adhesive; and as a thickening agent for suspensions. Additionally, dextrin has been used as a source of carbohydrate by people with special dietary requirements because it has a low electrolyte content and is free of lactose and sucrose. Dextrin is also used in cosmetics. Safety Profile Mdly toxic by intravenous route. When heated to decomposition it emits acrid smoke and irritating fumes. Safety Dextrin is generally regarded as a nontoxic and nonirritant material at the levels employed as an excipient. Larger quantities are used as a dietary supplement without adverse effects, although ingestion of very large quantities may be harmful. LD50 (mouse, IV): 0.35g/kg storage Physical characteristics of dextrin may vary slightly depending on the method of manufacture and on the source material. In aqueous solutions, dextrin molecules tend to aggregate as density, temperature, pH, or other characteristics change. An increase in viscosity is caused by gel at ion or retro gradation as dextrin solutions age,and is particularly noticeable in the less-soluble maize starch dextrins. Dextrin solutions are thixotropic, becoming less viscous when sheared but changing to a soft paste or gel when allowed to stand. However, acids that are present in dextrin as residues from manufacturing can cause further hydrolysis, which results in a gradual thinning of solutions. Residual acid, often found in lesssoluble dextrins such as pyrodextrin, will also cause a reduction in viscosity during dry storage. To eliminate these problems, dextrin manufacturers neutralize dextrins of low solubility with ammonia or sodium carbonate in the cooling vessel. The bulk material should be stored in a well-closed container in a cool, dry place. Incompatibilities Incompatible with strong oxidizing agents. Regulatory Status GRAS listed.Included in the FDA Inactive Ingredients Database(IV injections, oral tablets and topical preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.   Dextrin Preparation Products And Raw materials Raw materials Phosphoric acid Preparation Products SPINOSAD-->1H-as-Indaceno3,2-doxacyclododecin-7,15-dione, 2-(6-deoxy-2,3,4-tri-O-methyl-.alpha.-L-mannopyranosyl)oxy-13-(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yloxy-9-ethyl-2,3,3a,5a,5b,6,9,10,11,12,13,14,16a,16b-tetradecahydro-4,14-dimethyl-, (2-->CARAMEL-->D-(+)-Maltose monohydrate-->Oxytetracycline-->Cyclooctapentylose-->BETA-CYCLODEXTRIN-->BILE SALTS-->α-Amylase-->4-Bromobiphenyl-->chlorophyllin copper complex sodium salt-->D-Cycloserine-->Antifreeze-->Glucosyl licorice-->C.I.Basic Blue 26-->SAFFLOWER YELLOW-->Cyclohexapentylose-->Clavulanic acid-->compound nutrient-->Laminaria, ext.