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China Biggest Factory & Manufacturer supply G418 Sulfate (Geneticin) CAS NO.108321-42-2
- FOB Price: USD: 1.00-2.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,Other
- Available Specifications:
AAAAA(50-100)KilogramAAAAA(100-500)Kilogram
- Product Details
Keywords
- G418 Sulfate
- Geneticin
- 108321-42-2
Quick Details
- ProName: China Biggest Factory & Manufacturer s...
- CasNo: 108321-42-2
- Molecular Formula: 56-69-9
- Appearance: white powder
- Application: chemicals industry
- DeliveryTime: 3-5 days
- PackAge: 25KG/Drum
- Port: Shanghai Guangzhou Qingdao Shenzhen
- ProductionCapacity: 5 Metric Ton/Month
- Purity: 99%
- Storage: 2-8°C
- Transportation: By air /Sea/ coruier
- LimitNum: 1 Kilogram
- Color: white
- Melting point: ≥350°C
- Boiling point: 363.24°C (rough estimate)
- density: 1.667
- solubility: 1 M NaOH: 10 mg/mL, dark green
- Water Solubility: <0.1 g/100 mL at 21 oC
- Stability: Stable. Combustible. Incompatible with...
Superiority
| Geneticin Basic information |
| Product Name: | Geneticin |
| Synonyms: | TRYPSIN INHIBITOR SOYBEAN REAGENT GRADE;G-418 disulfate,Geneticin;Geneticin Disulfate (G418), Antibiotic for Culture Media Use Only;Geneticin disulfate saltPotency ≥ 700 ug/mg (anhydrous basis);Antibiotic G418 Geneticin®;2-[4,6-diamino-3-[3-amino-4,5-dihydroxy-6-(1-hydroxyethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol,sulfuric acid;G 418 Sulfate, Sterile-Filtered Aqueous Solution, Cell Culture Tested;D-Streptamine, O-2-amino-2,7-dideoxy-D-glycero-α-D-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2) |
| CAS: | 108321-42-2 |
| MF: | C20H42N4O14S |
| MW: | 594.63 |
| EINECS: | 600-864-4 |
| Product Categories: | Antibiotic Explorer;antibiotic;Inhibitors |
| Mol File: | 108321-42-2.mol |
| Geneticin Chemical Properties |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL |
| form | white powder |
| color | white to off-white |
| optical activity | [α]/D (Specific Rotation: +104.4o (c=0.3% in H2O at 26oC)) |
| Water Solubility | soluble |
| InChIKey | QNQZPJLBGRQFDD-ZLRXUJDMSA-N |
| Safety Information |
| Hazard Codes | Xn,Xi |
| Risk Statements | 20/21/22-36/37/38-42/43 |
| Safety Statements | 22-24/25-36/37-23-36-26-45 |
| WGK Germany | 3 |
| RTECS | CB9378500 |
| HS Code | 29419090 |
| MSDS Information |
| Geneticin Usage And Synthesis |
| Chemical Properties | white to off-white powder |
| Uses | antibacterial |
| Uses | membrane-permeant allosteric effector of hemoglobin therapeutic in cardiovascular diseases and cancer |
| Uses | Antihypertensive |
| Uses | Plant cell culture, tested |
| Uses | Geneticin Disulfate Salt, is an aminoglycoside antibiotic, structurlly similar to Gentamicin B1. It is produced by Micromonospora rhodorangea. G418 blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. |
| General Description |
The optimal concentration of G418 for selection of resistance will vary according to the organism and/or cell type under investigation. In general, the concentration of active drug required for selection is as follows: Dictyostelium sp.: 10-100 μg/ml Plant cells: 10-100 μg/ml Yeast cells: 0.5-1.0 μg/ml Mammalian cells: 0.1-2.0 μg/ml |
| Biochem/physiol Actions | Mode of Action: G418 blocks polypeptide synthesis and protein elongation by inhibiting synthesis at the 70S and 80S ribosomes.Antimicrobial Spectrum: G418 selects for cells stably transfected with an iNOS promoter construct and neomycin resistance gene and shows activity against protozoa and helminthes. |
| Geneticin Preparation Products And Raw materials |
Details
| Geneticin Basic information |
| Product Name: | Geneticin |
| Synonyms: | TRYPSIN INHIBITOR SOYBEAN REAGENT GRADE;G-418 disulfate,Geneticin;Geneticin Disulfate (G418), Antibiotic for Culture Media Use Only;Geneticin disulfate saltPotency ≥ 700 ug/mg (anhydrous basis);Antibiotic G418 Geneticin®;2-[4,6-diamino-3-[3-amino-4,5-dihydroxy-6-(1-hydroxyethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol,sulfuric acid;G 418 Sulfate, Sterile-Filtered Aqueous Solution, Cell Culture Tested;D-Streptamine, O-2-amino-2,7-dideoxy-D-glycero-α-D-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2) |
| CAS: | 108321-42-2 |
| MF: | C20H42N4O14S |
| MW: | 594.63 |
| EINECS: | 600-864-4 |
| Product Categories: | Antibiotic Explorer;antibiotic;Inhibitors |
| Mol File: | 108321-42-2.mol |
| Geneticin Chemical Properties |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL |
| form | white powder |
| color | white to off-white |
| optical activity | [α]/D (Specific Rotation: +104.4o (c=0.3% in H2O at 26oC)) |
| Water Solubility | soluble |
| InChIKey | QNQZPJLBGRQFDD-ZLRXUJDMSA-N |
| Safety Information |
| Hazard Codes | Xn,Xi |
| Risk Statements | 20/21/22-36/37/38-42/43 |
| Safety Statements | 22-24/25-36/37-23-36-26-45 |
| WGK Germany | 3 |
| RTECS | CB9378500 |
| HS Code | 29419090 |
| MSDS Information |
| Geneticin Usage And Synthesis |
| Chemical Properties | white to off-white powder |
| Uses | antibacterial |
| Uses | membrane-permeant allosteric effector of hemoglobin therapeutic in cardiovascular diseases and cancer |
| Uses | Antihypertensive |
| Uses | Plant cell culture, tested |
| Uses | Geneticin Disulfate Salt, is an aminoglycoside antibiotic, structurlly similar to Gentamicin B1. It is produced by Micromonospora rhodorangea. G418 blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. |
| General Description |
The optimal concentration of G418 for selection of resistance will vary according to the organism and/or cell type under investigation. In general, the concentration of active drug required for selection is as follows: Dictyostelium sp.: 10-100 μg/ml Plant cells: 10-100 μg/ml Yeast cells: 0.5-1.0 μg/ml Mammalian cells: 0.1-2.0 μg/ml |
| Biochem/physiol Actions | Mode of Action: G418 blocks polypeptide synthesis and protein elongation by inhibiting synthesis at the 70S and 80S ribosomes.Antimicrobial Spectrum: G418 selects for cells stably transfected with an iNOS promoter construct and neomycin resistance gene and shows activity against protozoa and helminthes. |
| Geneticin Preparation Products And Raw materials |