China Northwest Largest Factory Manufacturer supply USP Grade POLYVINYLPYRROLIDONE CROSS LINKED(PVPP)/POLYVIDONE Annual 2000MT/Year

                  

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Product details :

Product Name:Crospovidone

 

Chemical Description:Croslinked PVP,Crospovidone,Insoluble PVP,Pollyvinylpolypyrrolidone

 

INCI/CTFA:Insoluble PVP

 

Pharmacopeia Name:Crospovidone (Crospovidonum)

 

CAS NO.:9003-39-8,25249-54-1

 

Formula Structure:

 

Product Properties: Crospovidone is hygroscopic,insoluble in water and all other common solvents,but it swells rapidly in aqueous solutbition without any gel froms.Its; classified as Crospovidone Type A and Type B according to the different particle size.

 

Applications:In the pharmaceutical industry,Crospovidone are widely used as 1)Disintergrating agent,2)Stabilizer for suspension,3)Moisture Absorbent, 4)Complextant of Polyphenols and Tannin for the extract formulations.

 

Specifications:

Product	Crospovidone Type A	Crospovidone Type B
Appearance	White or yellowish-white powder or flakes
Identifications	Meet ID Tests
Solubility	Practically insoluble in water,in alcohol and in methylene chloride
Water- soluble substances	1.0% max	1.0% max
pH((1% in water)	5.0 –8.0	5.0 –8.0
Loss on Drying	5.0% max.	5.0% max.
Sulphated Ash	0.1% max.	0.1% max.
Nitrogen content	11.0 -12.8 %	11.0 -12.8 %
Impurity A	10 ppm max.	10 ppm max.
Peroxide(As H2O2)	400 ppm max.	1000 ppm max.
Heavy Metal	10 ppm max.	10 ppm max.
Particle Size(μm), ≥80%	50-300	5-50

Polyvinylpyrrolidone cross-linked Basic information

Indications and Usage Toxicity

Product Name:	Polyvinylpyrrolidone cross-linked
Synonyms:	K-30;PVPP;PVPD;PVP K-30;POLYVIDONE;POLYVIDONUM;POLYVINYLPOLYPYRROLIDONE;POLYVINYLPYRROLIDONE CROSS LINKED
CAS:	25249-54-1
MF:	C6H9NO
MW:	111.14176
EINECS:	607-660-4
Product Categories:	Pyrrolidones;API;Beverage;Other Reagents for Food Analysis;Reagents for Analysis of Proteins;Reagents for Food Analysis;Vinylpyridine and Vinypyrrolidone Polymers;Analytical Reagents;Analytical/Chromatography;Application Specific Reagents;Food &;Hydrophobic Polymers;Materials Science;Poly(vinylpyrrolidone);Polymer Science;Polymers
Mol File:	25249-54-1.mol

Polyvinylpyrrolidone cross-linked Chemical Properties

Melting point	~165 °C (dec.)(lit.)
form	powder
color	White to off-white
Water Solubility	Insoluble in water, acid and alkaline.
CAS DataBase Reference	25249-54-1

Safety Information

Safety Statements	22-24/25
WGK Germany	1
RTECS	TR8370000
HS Code	39059900

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

Polyvinylpyrrolidone cross-linked Usage And Synthesis

Indications and Usage	Polyvinylpyrrolidone (PVP) is a polymer of vinyl pyrrolidone. It is divided based on degree of polymerization into soluble PVP and insoluble polyvinyl polypyrrolidone (PVPP). Commercially available PVPs are divided into four viscosity grades by K value (Fikentscher K): K-15, K-30, K-60, K-90, with respective molecular masses of 10000, 40000, 160000, and 360000. K value or relative molecular mass is one of the important factors determining the various properties of PVP. Polyvinylpyrrolidone is one of the three major new medicinal materials. It can be used for tablets, granules, a cosolvent for injections, glidant for capsules, liquid preparation and dispersant for colorants, stabilizer for enzymes and thermosensitive drugs, precipitant for poorly soluble drugs, and a removal agent and lubricant for eye drops, etc. The combination of PVP with toxins, drugs, and chemical agents can reduce their toxicity. Complexes with iodine are very stable, with good bactericidal effects, reducing toxicity. Used in industry as a foaming polystyrene additive, gelling agent, stabilizer, fiber treatment agent, paper processing aid, adhesive, and thickener. Some dyes can also be strongly complexed with PVP, which is the basis for polyvinylpyrrolidone PVP as a dye bleaching agent. Polyvinylpyrrolidone PVP and its copolymer is an important raw material for cosmetics, mainly used for hair styling agents. The film it forms on hair is flexible and shiny, with good combing performance, without attracting dust. Different resins can satisfy different relative humidity and climatic conditions, so it is an indispensable raw material for styling hair cream, hair gel, and mousse. It can also be used as a cosmetic skin care moisturizing agent, base material of grease, hair coloring dispersant, and foam stabilizer. It can improve the consistency of shampoo. Insoluble PVP is a stabilizer for beer, fruit juice, vinegar, wine and so on, improving its clarity, color and taste.
Toxicity	ADI 0-50(FAO/WHO, 2001) LD50>100g/kg(rats, orally administered) LD5012g/kg Can be safely used in food
Chemical Properties	white to off-white micro-crystalline powder
Uses	PVP (polyvinylpyrrolidone) is a chemical ingredient that, depending on the formulatory requirement, can act as a binder, viscosity controller, emulsion stabilizer, or film former. Its benefits include water and wear resistance, pigment dispersion, a non-greasy feel, and improved stick integrity. PVP is commonly found in waterproof sunscreens, mascaras, and lipsticks in order to improve their wear.
Uses	Polyvinylpyrrolidone (PVP) has been used as a clarifying agent in the food industry.
Uses	Polyvinylpyrrolidone is used in coatings, printing ink, rubber, glass, leather, cosmetics, soaps, plastics, in paper making and as a stabilizer. It acts as a disintegrant in pharmaceutical tablets and as a fining to extract impurities. It is used to remove polyphenols in beer

 

If you are interested in our products, please kindly inquiry us at email:  sales@leader-biogroup.com

Product details :

Polyvinylpyrrolidone cross-linked Basic information

Indications and Usage Toxicity

Product Name:	Polyvinylpyrrolidone cross-linked
Synonyms:	K-30;PVPP;PVPD;PVP K-30;POLYVIDONE;POLYVIDONUM;POLYVINYLPOLYPYRROLIDONE;POLYVINYLPYRROLIDONE CROSS LINKED
CAS:	25249-54-1
MF:	C6H9NO
MW:	111.14176
EINECS:	607-660-4
Product Categories:	Pyrrolidones;API;Beverage;Other Reagents for Food Analysis;Reagents for Analysis of Proteins;Reagents for Food Analysis;Vinylpyridine and Vinypyrrolidone Polymers;Analytical Reagents;Analytical/Chromatography;Application Specific Reagents;Food &;Hydrophobic Polymers;Materials Science;Poly(vinylpyrrolidone);Polymer Science;Polymers
Mol File:	25249-54-1.mol

Polyvinylpyrrolidone cross-linked Chemical Properties

Melting point	~165 °C (dec.)(lit.)
form	powder
color	White to off-white
Water Solubility	Insoluble in water, acid and alkaline.
CAS DataBase Reference	25249-54-1

Safety Information

Safety Statements	22-24/25
WGK Germany	1
RTECS	TR8370000
HS Code	39059900

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

Polyvinylpyrrolidone cross-linked Usage And Synthesis

Indications and Usage	Polyvinylpyrrolidone (PVP) is a polymer of vinyl pyrrolidone. It is divided based on degree of polymerization into soluble PVP and insoluble polyvinyl polypyrrolidone (PVPP). Commercially available PVPs are divided into four viscosity grades by K value (Fikentscher K): K-15, K-30, K-60, K-90, with respective molecular masses of 10000, 40000, 160000, and 360000. K value or relative molecular mass is one of the important factors determining the various properties of PVP. Polyvinylpyrrolidone is one of the three major new medicinal materials. It can be used for tablets, granules, a cosolvent for injections, glidant for capsules, liquid preparation and dispersant for colorants, stabilizer for enzymes and thermosensitive drugs, precipitant for poorly soluble drugs, and a removal agent and lubricant for eye drops, etc. The combination of PVP with toxins, drugs, and chemical agents can reduce their toxicity. Complexes with iodine are very stable, with good bactericidal effects, reducing toxicity. Used in industry as a foaming polystyrene additive, gelling agent, stabilizer, fiber treatment agent, paper processing aid, adhesive, and thickener. Some dyes can also be strongly complexed with PVP, which is the basis for polyvinylpyrrolidone PVP as a dye bleaching agent. Polyvinylpyrrolidone PVP and its copolymer is an important raw material for cosmetics, mainly used for hair styling agents. The film it forms on hair is flexible and shiny, with good combing performance, without attracting dust. Different resins can satisfy different relative humidity and climatic conditions, so it is an indispensable raw material for styling hair cream, hair gel, and mousse. It can also be used as a cosmetic skin care moisturizing agent, base material of grease, hair coloring dispersant, and foam stabilizer. It can improve the consistency of shampoo. Insoluble PVP is a stabilizer for beer, fruit juice, vinegar, wine and so on, improving its clarity, color and taste.
Toxicity	ADI 0-50(FAO/WHO, 2001) LD50>100g/kg(rats, orally administered) LD5012g/kg Can be safely used in food
Chemical Properties	white to off-white micro-crystalline powder
Uses	PVP (polyvinylpyrrolidone) is a chemical ingredient that, depending on the formulatory requirement, can act as a binder, viscosity controller, emulsion stabilizer, or film former. Its benefits include water and wear resistance, pigment dispersion, a non-greasy feel, and improved stick integrity. PVP is commonly found in waterproof sunscreens, mascaras, and lipsticks in order to improve their wear.
Uses	Polyvinylpyrrolidone (PVP) has been used as a clarifying agent in the food industry.
Uses	Polyvinylpyrrolidone is used in coatings, printing ink, rubber, glass, leather, cosmetics, soaps, plastics, in paper making and as a stabilizer. It acts as a disintegrant in pharmaceutical tablets and as a fining to extract impurities. It is used to remove polyphenols in beer