China Biggest Factory manufacturer supply Selamectin CAS NO.220119-17-5
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- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,Other
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- Product Details
Keywords
- Selamectin
- Selamectin
- 220119-17-5
Quick Details
- ProName: China Biggest Factory manufacturer sup...
- CasNo: 220119-17-5
- Molecular Formula: 220119-17-5
- Appearance: white powder
- Application: Pharm chemicals industry
- DeliveryTime: 3-5 days
- PackAge: 25KG/Drum
- Port: Shanghai Guangzhou Qingdao Shenzhen
- ProductionCapacity: 2 Metric Ton/Month
- Purity: 99%
- Storage: 2-8°C
- Transportation: By air /Sea/ coruier
- LimitNum: 1 Kilogram
- Moisture Content: 1
- Impurity: 1
- Color: white
- Melting point: ≥350°C
- Boiling point: 363.24°C (rough estimate)
- density: 1.667
- solubility: 1 M NaOH: 10 mg/mL, dark green
- Water Solubility: <0.1 g/100 mL at 21 oC
- Stability: Stable. Combustible. Incompatible with...
Superiority
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Group profiles
Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research. Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products. Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation. We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.
Details
Product information
Selamectin Basic information |
Product Name: | Selamectin |
Synonyms: | Selamectin;AverMectin A1a,25-cyclohexyl-4'-O-de(2,6-dideoxy-3-O-Methyl-a-L-arabino-hexopyranosyl)-5-deMethoxy-25-de(1-Methylpropyl)-22,23-dihydro-5-(hydroxyiMino)-,(5Z)-;hypnocarpic acid;(5Z)-25-Cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)-avermectin A1a;Revolution (antibiotic);Stronghold;Selamectin CRS;Avermectin A1a, 25-cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)-, (5Z)- |
CAS: | 220119-17-5 |
MF: | C43H63NO11 |
MW: | 769.97 |
EINECS: | 815-979-7 |
Product Categories: | Anthelmintic;ectoparasiticide;API |
Mol File: | 220119-17-5.mol |
Selamectin Chemical Properties |
Melting point | >180°C |
Boiling point | 917.0±65.0 °C(Predicted) |
density | 1.35±0.1 g/cm3(Predicted) |
storage temp. | Sealed in dry,Room Temperature |
solubility | Chloroform (Slightly), Dichloromethane (Slightly, Heated), DMSO (Slightly), Etha |
pka | 10.34±0.70(Predicted) |
form | neat |
color | White to Yellow |
Stability: | Hygroscopic |
InChIKey | AFJYYKSVHJGXSN-KAJWKRCWSA-N |
CAS DataBase Reference | 220119-17-5 |
Safety Information |
WGK Germany | 3 |
HS Code | 2932206000 |
MSDS Information |
Selamectin Usage And Synthesis |
Description | Selamectin is formulated as a spot-on for cats and dogs to control fleas (Ctenocephalides spp.) and flea-allergy dermatitis, to prevent heartworm disease, and to control ear mites (Otodectes cynotes) in cats and dogs. It is also approved for the treatment and control of sarcoptic mange (Sarcoptes scabiei) in dogs and hookworms (Ancylostoma tubaeformis) and roundworms (Toxocara cati) in cats. |
Description | Selamectin is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. At 0.1 μg/ml, selamectin is reported to inhibit growth in an H. contortus larval development assay. |
Uses | Selamectin is a topical parasiticide and also used as a veterinary antihelminithic agent on animals. |
Uses | Selamectin is a semi-synthetic avermectin derivative prepared by selective hydrolysis and oximation of doramectin. Selamectin is a potent nematocide used for the treatment of endo- and exo- parasites of domestic animals, notably cats and dogs. Like the other milbemycin/avermectins, selamectin selectively binds to parasite glutamate-gated chloride ion channels and disrupts neurotransmission leading to paralysis and death of the parasite. |
Veterinary Drugs and Treatments | Topical selamectin (Revolution —Pfizer) is indicated for flea infestations (Ctenocephalides felis), prevention of heartworm disease (Dirofilaria immitis), and for ear mites (Otodectes cynotis) in both dogs and cats. Additionally in dogs, it is indicated for sarcoptic mange (Sarcoptes scabeii), and tick infestations (Dermacentor variabilis). In cats: hookworm (Ancylostoma tubaeforme) and roundworm (Toxocara cati). The product (Revolution ) is labeled as not effective against either adult heartworms or clearing circulating microfilaria, but it possibly may have some efficacy with prolonged, continuous administration (Atkins 2007b). |
Toxicity evaluation | Acute oral LD50 for rats: >1,600 mg/kg |
Selamectin Preparation Products And Raw materials |