China Largest Factory Manufacturer sales Dibutyl sebacate CAS 109-43-3 CAS NO.109-43-3

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Dibutyl sebacate Basic information Product Name: Dibutyl sebacate Synonyms: DIBUTYL SEBACATE, TECH.;dibutyl-1,10-decanedioate;Decanedioic acid dibutyl;Dibutyl sebacate,Sebacic acid dibutyl ester;Dibutyl Sebacate (1 mL) (AS);Dibutyl Sebacate (AS);Dibutyl Sebacate (1 mL);Dibutyl sebacinate CAS: 109-43-3 MF: C18H34O4 MW: 314.46 EINECS: 207-395-0 Product Categories: pharmacetical;Piperazine derivates;Fatty Acid Esters (Plasticizer);Functional Materials;Plasticizer Mol File: 109-43-3.mol   Dibutyl sebacate Chemical Properties Melting point  205 °C (dec.)(lit.) Boiling point  178-179 °C3 mm Hg(lit.) density  0.94 refractive index  n20/D 1.441(lit.) FEMA  2373 | DIBUTYL SEBACATE Fp  >230 °F storage temp.  Sealed in dry,Room Temperature solubility  hexane, toluene, ethanol and acetone: soluble form  Liquid Specific Gravity 0.937 (20/4℃) color  Clear Water Solubility  50mg/L(temperature not stated) JECFA Number 625 BRN  1798308 CAS DataBase Reference 109-43-3(CAS DataBase Reference) NIST Chemistry Reference Di-n-butyl sebacate(109-43-3) EPA Substance Registry System Dibutyl sebacate (109-43-3)   Safety Information Hazard Codes  Xn,Xi Risk Statements  40-36/37/38 Safety Statements  36/37-36-26 WGK Germany  3 RTECS  VS1150000 TSCA  Yes HS Code  29171390 Hazardous Substances Data 109-43-3(Hazardous Substances Data) Toxicity LD50 oral in rat: 14870mg/kg MSDS Information Provider Language Dibutyl sebacate English SigmaAldrich English ACROS English ALFA English   Dibutyl sebacate Usage And Synthesis Chemical Properties clear liquid Chemical Properties Dibutyl sebacate is a clear, colorless, oily liquid with a bland to slight butyl odor. Uses Dibutyl sebacate (DBS) is a dibutyl ester of sebacic acid. Dibutyl sebacate can be used for plastics in use in the food packaging industry, in plastics used for medical devices, and for pharmaceutical applications. Dibutyl sebacate is also used as a desensitizer in Otto fuel II, a torpedo monopropellant. Uses Dibutyl sebacate has been used as a plasticizer to prepare free ethylcellulose films. It can be utilized as a core in liquid-core capsules with cross-linked alginate/polyacrylamide membrane prepared via co-extrusion jet-break-up method for the extraction of the pesticide, atrazine. Production Methods Dibutyl sebacate is manufactured by the esterification of n-butanol and sebacic acid in the presence of a suitable catalyst, and by the distillation of sebacic acid with n-butanol in the presence of concentrated acid. Preparation By distillation of sebacic acid with butyl alcohol in the presence of concentrated HCl in benzene solution or by reacting butyl alcohol and sebacyl chloride General Description Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Dibutyl sebacate is a commonly used plasticizer, which can be synthesized by the reaction of butyl alcohol and sebacyl chloride or by the distillation of sebacic acid with butyl alcohol in the presence of concentrated hydrochloric acid in benzene solution. Pharmaceutical Applications Dibutyl sebacate is used in oral pharmaceutical formulations as a plasticizer for film coatings on tablets, beads, and granules, at concentrations of 10–30% by weight of polymer. It is also used as a plasticizer in controlled-release tablets and microcapsule preparations. Dibutyl sebacate is also used as a synthetic flavor and flavor adjuvant in food products;for example,up to 5ppm is used in ice cream and nonalcoholic beverages. Safety Profile Mddly toxic by ingestion. Experimental reproductive effects. Combustible liquid when exposed to heat or flame; can react with oxidzing materials. To fight fire, use CO2 position it emits acrid smoke and fumes. See also ESTERS and n-BUTYL. ALCOHOL. Safety Dibutyl sebacate is used in cosmetics, foods, and oral pharmaceutical formulations, and is generally regarded as a nontoxic and nonirritant material. Following oral administration, dibutyl sebacate is metabolized in the same way as fats. In humans, direct eye contact and prolonged or repeated contact with the skin may cause very mild irritation. Acute animal toxicity tests and long-term animal feeding studies have shown no serious adverse effects to be associated with orally administered dibutyl sebacate. LD50 (rat, oral): 16g/kg storage Dibutyl sebacate should be stored in a closed container in a cool, dry location. Dibutyl sebacate is stable under the recommended storage conditions and as used in specified applications under most conditions ofuse.Asanester,dibutylsebacatemayhydrolyzeinthe presence of water at high or low pH conditions. Incompatibilities Dibutyl sebacate is incompatible with strong oxidizing materials and strong alkalis. Regulatory Status Included in the FDA Inactive Ingredients Database (oral capsules, granules, film-coated, sustained action, and tablets). Included in the Canadian List of Acceptable Non-medicinal Ingredients.   Dibutyl sebacate Preparation Products And Raw materials Raw materials tert-Butanol-->Castor oil-->Sebacic acid-->Sebacoyl chloride

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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Dibutyl sebacate Basic information Product Name: Dibutyl sebacate Synonyms: DIBUTYL SEBACATE, TECH.;dibutyl-1,10-decanedioate;Decanedioic acid dibutyl;Dibutyl sebacate,Sebacic acid dibutyl ester;Dibutyl Sebacate (1 mL) (AS);Dibutyl Sebacate (AS);Dibutyl Sebacate (1 mL);Dibutyl sebacinate CAS: 109-43-3 MF: C18H34O4 MW: 314.46 EINECS: 207-395-0 Product Categories: pharmacetical;Piperazine derivates;Fatty Acid Esters (Plasticizer);Functional Materials;Plasticizer Mol File: 109-43-3.mol   Dibutyl sebacate Chemical Properties Melting point  205 °C (dec.)(lit.) Boiling point  178-179 °C3 mm Hg(lit.) density  0.94 refractive index  n20/D 1.441(lit.) FEMA  2373 | DIBUTYL SEBACATE Fp  >230 °F storage temp.  Sealed in dry,Room Temperature solubility  hexane, toluene, ethanol and acetone: soluble form  Liquid Specific Gravity 0.937 (20/4℃) color  Clear Water Solubility  50mg/L(temperature not stated) JECFA Number 625 BRN  1798308 CAS DataBase Reference 109-43-3(CAS DataBase Reference) NIST Chemistry Reference Di-n-butyl sebacate(109-43-3) EPA Substance Registry System Dibutyl sebacate (109-43-3)   Safety Information Hazard Codes  Xn,Xi Risk Statements  40-36/37/38 Safety Statements  36/37-36-26 WGK Germany  3 RTECS  VS1150000 TSCA  Yes HS Code  29171390 Hazardous Substances Data 109-43-3(Hazardous Substances Data) Toxicity LD50 oral in rat: 14870mg/kg MSDS Information Provider Language Dibutyl sebacate English SigmaAldrich English ACROS English ALFA English   Dibutyl sebacate Usage And Synthesis Chemical Properties clear liquid Chemical Properties Dibutyl sebacate is a clear, colorless, oily liquid with a bland to slight butyl odor. Uses Dibutyl sebacate (DBS) is a dibutyl ester of sebacic acid. Dibutyl sebacate can be used for plastics in use in the food packaging industry, in plastics used for medical devices, and for pharmaceutical applications. Dibutyl sebacate is also used as a desensitizer in Otto fuel II, a torpedo monopropellant. Uses Dibutyl sebacate has been used as a plasticizer to prepare free ethylcellulose films. It can be utilized as a core in liquid-core capsules with cross-linked alginate/polyacrylamide membrane prepared via co-extrusion jet-break-up method for the extraction of the pesticide, atrazine. Production Methods Dibutyl sebacate is manufactured by the esterification of n-butanol and sebacic acid in the presence of a suitable catalyst, and by the distillation of sebacic acid with n-butanol in the presence of concentrated acid. Preparation By distillation of sebacic acid with butyl alcohol in the presence of concentrated HCl in benzene solution or by reacting butyl alcohol and sebacyl chloride General Description Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Dibutyl sebacate is a commonly used plasticizer, which can be synthesized by the reaction of butyl alcohol and sebacyl chloride or by the distillation of sebacic acid with butyl alcohol in the presence of concentrated hydrochloric acid in benzene solution. Pharmaceutical Applications Dibutyl sebacate is used in oral pharmaceutical formulations as a plasticizer for film coatings on tablets, beads, and granules, at concentrations of 10–30% by weight of polymer. It is also used as a plasticizer in controlled-release tablets and microcapsule preparations. Dibutyl sebacate is also used as a synthetic flavor and flavor adjuvant in food products;for example,up to 5ppm is used in ice cream and nonalcoholic beverages. Safety Profile Mddly toxic by ingestion. Experimental reproductive effects. Combustible liquid when exposed to heat or flame; can react with oxidzing materials. To fight fire, use CO2 position it emits acrid smoke and fumes. See also ESTERS and n-BUTYL. ALCOHOL. Safety Dibutyl sebacate is used in cosmetics, foods, and oral pharmaceutical formulations, and is generally regarded as a nontoxic and nonirritant material. Following oral administration, dibutyl sebacate is metabolized in the same way as fats. In humans, direct eye contact and prolonged or repeated contact with the skin may cause very mild irritation. Acute animal toxicity tests and long-term animal feeding studies have shown no serious adverse effects to be associated with orally administered dibutyl sebacate. LD50 (rat, oral): 16g/kg storage Dibutyl sebacate should be stored in a closed container in a cool, dry location. Dibutyl sebacate is stable under the recommended storage conditions and as used in specified applications under most conditions ofuse.Asanester,dibutylsebacatemayhydrolyzeinthe presence of water at high or low pH conditions. Incompatibilities Dibutyl sebacate is incompatible with strong oxidizing materials and strong alkalis. Regulatory Status Included in the FDA Inactive Ingredients Database (oral capsules, granules, film-coated, sustained action, and tablets). Included in the Canadian List of Acceptable Non-medicinal Ingredients.   Dibutyl sebacate Preparation Products And Raw materials Raw materials tert-Butanol-->Castor oil-->Sebacic acid-->Sebacoyl chloride