China Largest Factory Manufacturer sales Dodecyl gallate CAS 1166-52-5 CAS NO.1166-52-5

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Dodecyl gallate

Product name: Dodecyl gallate

CAS NO.: 1166-52-5

Alias: Lauryl gallate; Dodecyl 3,4,5-trihydroxybenzoate; Dodocyl gallate,EINECS 214-620-6

Molecular formula: C₁₉H₃₀O₅              

Molecular weight: 338.44

Content: ≥98.5%                        

Melting point: 95-99℃                 

Function: used as food and cosmetic additives

Dodecyl gallate Basic information Product Name: Dodecyl gallate Synonyms: nipagallinla;Progallin LA;progallinla;n-dodecyl 3,4,5-trihydroxybenzoate;Lauryl Gallate (Dodecyl Gallate);DODECYL GALLATE( DODECYL 3,4,5-TRIHYDROXYBENZOATE);3mg/kg;96-97℃ CAS: 1166-52-5 MF: C19H30O5 MW: 338.44 EINECS: 214-620-6 Product Categories: Aromatic Esters Mol File: 1166-52-5.mol   Dodecyl gallate Chemical Properties Melting point  94-97 °C (lit.) Boiling point  394.57°C (rough estimate) density  1.0677 (rough estimate) refractive index  1.6120 (estimate) storage temp.  Store below +30°C. solubility  Very slightly soluble or practically insoluble in water, freely soluble in ethanol (96 per cent), slightly soluble in methylene chloride. form  neat pka 7.93±0.25(Predicted) Water Solubility  practically insoluble Sensitive  Air Sensitive BRN  2701981 InChIKey RPWFJAMTCNSJKK-UHFFFAOYSA-N CAS DataBase Reference 1166-52-5(CAS DataBase Reference) NIST Chemistry Reference Gallic acid, n-dodecyl ester(1166-52-5) EPA Substance Registry System Benzoic acid, 3,4,5-trihydroxy-, dodecyl ester (1166-52-5)   Safety Information Hazard Codes  Xi Risk Statements  43 Safety Statements  24-37 RIDADR  3335 WGK Germany  1 RTECS  DH9100000 TSCA  Yes HS Code  29182950 Toxicity LD50 orally in Rabbit: 5000 mg/kg MSDS Information Provider Language Dodecyl 3,4,5-trihydroxybenzoate English SigmaAldrich English ACROS English ALFA English   Dodecyl gallate Usage And Synthesis Description This gallate ester (E 310) is an antioxidant added to foods and cosmetics to prevent oxidation of unsaturated fatty acids. Cases have been reported in workers in the food industry, gallate being contained in margarine. It is also present in washing powder. Chemical Properties white to cream powder Uses Dodecyl Gallate is an antioxidant used in cream cheese, instant mashed potatoes, margarine, fats, and oils. Uses Dodecyl gallate is an antioxidant in cosmetic and pharmaceutical creams and emulsions, various fats, oils, waxes, and foods, such as margarine. Uses Dodecyl 3,4,5-Trihydroxybenzoate is used in method for stabilizing the pH of an aqueous compound comprising drug. General Description Lauryl gallate is a major monomer flavanol found in green tea and shows antioxidant activity in polymers. Contact allergens This gallic acid ester (E 310) is an antioxidant added to food and cosmetics to prevent oxidation of unsaturated fatty acids. Cases were reported in workers of the food industry, gallate being contained in margarine, and from washing powder. Safety Profile Poison by ingestion and inhalation. Moderately toxic by skin contact. A severe eye irritant. Questionable carcinogen with experimental tumorigenic data. A pesticide. When heated to decomposition it emits very toxic fumes of NOx. Carcinogenicity In a 2-year feeding study, with the administration of up to 5 mg/kg of feed to rats, no increase in tumor incidence was noted . In female mice, a dermal injection of dodecyl gallate (100 nmol in 0.2mL acetone) inhibits the formation of skin carcinomas and papillomas induced by the tumor promoter phorbol myristate and the initiator 7,12-dimethylbenz[a]anthracene .   Dodecyl gallate Preparation Products And Raw materials Raw materials 1-Dodecanol-->3,4,5-trihydroxybenzoyl chloride-->Gallic acid

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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                                                       Product information

Dodecyl gallate

Product name: Dodecyl gallate

CAS NO.: 1166-52-5

Alias: Lauryl gallate; Dodecyl 3,4,5-trihydroxybenzoate; Dodocyl gallate,EINECS 214-620-6

Molecular formula: C₁₉H₃₀O₅              

Molecular weight: 338.44

Content: ≥98.5%                        

Melting point: 95-99℃                 

Function: used as food and cosmetic additives

Dodecyl gallate Basic information Product Name: Dodecyl gallate Synonyms: nipagallinla;Progallin LA;progallinla;n-dodecyl 3,4,5-trihydroxybenzoate;Lauryl Gallate (Dodecyl Gallate);DODECYL GALLATE( DODECYL 3,4,5-TRIHYDROXYBENZOATE);3mg/kg;96-97℃ CAS: 1166-52-5 MF: C19H30O5 MW: 338.44 EINECS: 214-620-6 Product Categories: Aromatic Esters Mol File: 1166-52-5.mol   Dodecyl gallate Chemical Properties Melting point  94-97 °C (lit.) Boiling point  394.57°C (rough estimate) density  1.0677 (rough estimate) refractive index  1.6120 (estimate) storage temp.  Store below +30°C. solubility  Very slightly soluble or practically insoluble in water, freely soluble in ethanol (96 per cent), slightly soluble in methylene chloride. form  neat pka 7.93±0.25(Predicted) Water Solubility  practically insoluble Sensitive  Air Sensitive BRN  2701981 InChIKey RPWFJAMTCNSJKK-UHFFFAOYSA-N CAS DataBase Reference 1166-52-5(CAS DataBase Reference) NIST Chemistry Reference Gallic acid, n-dodecyl ester(1166-52-5) EPA Substance Registry System Benzoic acid, 3,4,5-trihydroxy-, dodecyl ester (1166-52-5)   Safety Information Hazard Codes  Xi Risk Statements  43 Safety Statements  24-37 RIDADR  3335 WGK Germany  1 RTECS  DH9100000 TSCA  Yes HS Code  29182950 Toxicity LD50 orally in Rabbit: 5000 mg/kg MSDS Information Provider Language Dodecyl 3,4,5-trihydroxybenzoate English SigmaAldrich English ACROS English ALFA English   Dodecyl gallate Usage And Synthesis Description This gallate ester (E 310) is an antioxidant added to foods and cosmetics to prevent oxidation of unsaturated fatty acids. Cases have been reported in workers in the food industry, gallate being contained in margarine. It is also present in washing powder. Chemical Properties white to cream powder Uses Dodecyl Gallate is an antioxidant used in cream cheese, instant mashed potatoes, margarine, fats, and oils. Uses Dodecyl gallate is an antioxidant in cosmetic and pharmaceutical creams and emulsions, various fats, oils, waxes, and foods, such as margarine. Uses Dodecyl 3,4,5-Trihydroxybenzoate is used in method for stabilizing the pH of an aqueous compound comprising drug. General Description Lauryl gallate is a major monomer flavanol found in green tea and shows antioxidant activity in polymers. Contact allergens This gallic acid ester (E 310) is an antioxidant added to food and cosmetics to prevent oxidation of unsaturated fatty acids. Cases were reported in workers of the food industry, gallate being contained in margarine, and from washing powder. Safety Profile Poison by ingestion and inhalation. Moderately toxic by skin contact. A severe eye irritant. Questionable carcinogen with experimental tumorigenic data. A pesticide. When heated to decomposition it emits very toxic fumes of NOx. Carcinogenicity In a 2-year feeding study, with the administration of up to 5 mg/kg of feed to rats, no increase in tumor incidence was noted . In female mice, a dermal injection of dodecyl gallate (100 nmol in 0.2mL acetone) inhibits the formation of skin carcinomas and papillomas induced by the tumor promoter phorbol myristate and the initiator 7,12-dimethylbenz[a]anthracene .   Dodecyl gallate Preparation Products And Raw materials Raw materials 1-Dodecanol-->3,4,5-trihydroxybenzoyl chloride-->Gallic acid