China Biggest Manufacturer factory sales Taurodeoxycholic Acid Sodium Salt CAS 1180-95-6 CAS NO.1180-95-6

                                PRODUCT DETAILS                           

Taurodeoxycholic acid sodium salt Basic information Product Name: Taurodeoxycholic acid sodium salt Synonyms: TAURODEOXYCHOLIC ACID SODIUM;TAURODEOXYCHOLIC ACID SODIUM SALT;Taurodeoxycholic acid sodium salt hydrate;SODIUM TAURODEOXYCHOLATE;SODIUM TAURODEOXYCHOLATE SODIUM SALT;SODIUM TAURODESOXYCHOLATE SODIUM SALT;2-[(3ALPHA,12ALPHA-DIHYDROXY-24-OXO-5BETA-CHOLAN-24-YL)-AMINO] ETHANESULFONIC ACID SODIUM SALT;5BETA-CHOLANIC ACID-3ALPHA,12ALPHA-DIOL 24-N-(2-SULFOETHYL)-AMIDE SODIUM CAS: 1180-95-6 MF: C26H44NNaO6S MW: 521.69 EINECS: 214-652-0 Product Categories: Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids Mol File: 1180-95-6.mol   Taurodeoxycholic acid sodium salt Chemical Properties Melting point  168 °C (dec.)(lit.) alpha  33 º (c=3, water) storage temp.  Keep in dark place,Inert atmosphere,Room temperature solubility  H2O: 0.5 M at 20 °C, clear, colorless to faintly yellow form  Solid color  White to Off-White Water Solubility  soluble CAS DataBase Reference 1180-95-6(CAS DataBase Reference)   Safety Information Hazard Codes  Xi Risk Statements  37 Safety Statements  24/25 WGK Germany  3 F  3-10 HS Code  29242990 MSDS Information Provider Language Taurodeoxycholic acid sodium salt English   Taurodeoxycholic acid sodium salt Usage And Synthesis Chemical Properties white to almost white crystalline powder Uses Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling. Purification Methods The Na salt is dissolved in the smallest volume of H2O, a saturated solution of aqueous NaCl/Et2O is added and the mixture is stored at 0o for 24hours. Then shake the mixture well, keep it in the cold for another day and filter the crystals with gentle shaking, wash them with ice-cold saturated aqueous NaCl saturated with Et2O, dry them over CaCl2 and extract them with absolute EtOH. Add ~10mL of H2O to the solid followed by enough Et2O to incipient cloudiness. Store it overnight at 0o. Add ice-cold Et2O to make 250mL, collect the crystals, wash them with Et2O then pet ether and dry them in air. The purification can be repeated with NaCl and Et2O with ~85% recovery. NB: precipitation will not occur unless enough H2O is present. Its solubility in H2O is 10%. [Cortese J Am Chem Soc 59 2532 1937.] The free acid has m 141-144o. [Norman Ark Kemi 8 331 1956.] It forms mixed micelles and solubilises some membrane proteins [Hajjar et al. J Biol Chem 2 5 8 192 1983]. [Beilstein 10 IV 1611.]   Taurodeoxycholic acid sodium salt Preparation Products And Raw materials Raw materials Deoxycholic acid-->Taurine

                                Group profiles

Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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                                                       Product information

Taurodeoxycholic acid sodium salt Basic information Product Name: Taurodeoxycholic acid sodium salt Synonyms: TAURODEOXYCHOLIC ACID SODIUM;TAURODEOXYCHOLIC ACID SODIUM SALT;Taurodeoxycholic acid sodium salt hydrate;SODIUM TAURODEOXYCHOLATE;SODIUM TAURODEOXYCHOLATE SODIUM SALT;SODIUM TAURODESOXYCHOLATE SODIUM SALT;2-[(3ALPHA,12ALPHA-DIHYDROXY-24-OXO-5BETA-CHOLAN-24-YL)-AMINO] ETHANESULFONIC ACID SODIUM SALT;5BETA-CHOLANIC ACID-3ALPHA,12ALPHA-DIOL 24-N-(2-SULFOETHYL)-AMIDE SODIUM CAS: 1180-95-6 MF: C26H44NNaO6S MW: 521.69 EINECS: 214-652-0 Product Categories: Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids Mol File: 1180-95-6.mol   Taurodeoxycholic acid sodium salt Chemical Properties Melting point  168 °C (dec.)(lit.) alpha  33 º (c=3, water) storage temp.  Keep in dark place,Inert atmosphere,Room temperature solubility  H2O: 0.5 M at 20 °C, clear, colorless to faintly yellow form  Solid color  White to Off-White Water Solubility  soluble CAS DataBase Reference 1180-95-6(CAS DataBase Reference)   Safety Information Hazard Codes  Xi Risk Statements  37 Safety Statements  24/25 WGK Germany  3 F  3-10 HS Code  29242990 MSDS Information Provider Language Taurodeoxycholic acid sodium salt English   Taurodeoxycholic acid sodium salt Usage And Synthesis Chemical Properties white to almost white crystalline powder Uses Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling. Purification Methods The Na salt is dissolved in the smallest volume of H2O, a saturated solution of aqueous NaCl/Et2O is added and the mixture is stored at 0o for 24hours. Then shake the mixture well, keep it in the cold for another day and filter the crystals with gentle shaking, wash them with ice-cold saturated aqueous NaCl saturated with Et2O, dry them over CaCl2 and extract them with absolute EtOH. Add ~10mL of H2O to the solid followed by enough Et2O to incipient cloudiness. Store it overnight at 0o. Add ice-cold Et2O to make 250mL, collect the crystals, wash them with Et2O then pet ether and dry them in air. The purification can be repeated with NaCl and Et2O with ~85% recovery. NB: precipitation will not occur unless enough H2O is present. Its solubility in H2O is 10%. [Cortese J Am Chem Soc 59 2532 1937.] The free acid has m 141-144o. [Norman Ark Kemi 8 331 1956.] It forms mixed micelles and solubilises some membrane proteins [Hajjar et al. J Biol Chem 2 5 8 192 1983]. [Beilstein 10 IV 1611.]   Taurodeoxycholic acid sodium salt Preparation Products And Raw materials Raw materials Deoxycholic acid-->Taurine