China Largest Manufacturer factory Supply Neopentyl Glycol CAS 126-30-7 CAS NO.126-30-7

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2,2-Dimethyl-1,3-propanediol Basic information Chemical Structure Application Product Name: 2,2-Dimethyl-1,3-propanediol Synonyms: 1,3-Dihydroxy-2,2-dimethylpropane;1,3-propanediol,2,2-dimethyl-;2,2-Dimethyl-1,3-dihydroxypropane;NEOPENTYL GLYCO;2,2-DIMETHYL-1,3-PROPANEDIOL (NPG);2,2-Dimethyl-1,3 propandiol;2,2-dimethyl-1,3-propanediol (Neopentyl Glycol);2,2-Dimethylpropan-1,3-diol CAS: 126-30-7 MF: C5H12O2 MW: 104.15 EINECS: 204-781-0 Product Categories: Organics;Intermediates of Dyes and Pigments;Pyridines Mol File: 126-30-7.mol   2,2-Dimethyl-1,3-propanediol Chemical Properties Melting point  126-128 °C Boiling point  208 °C density  1.06 vapor density  3.6 (vs air) vapor pressure  <0.8 mm Hg ( 20 °C) refractive index  1.4406 (estimate) Fp  107 °C storage temp.  Inert atmosphere,Room Temperature solubility  830g/l pka 14.57±0.10(Predicted) form  Crystalline Chunks color  White explosive limit 1.34%, 149°F Water Solubility  830 g/L (20 ºC) Sensitive  Hygroscopic Merck  14,6458 BRN  605291 Stability: Stable. Incompatible with strong oxidizing agents, acetic anhydride, acid chlorides, moisture. Combustible. CAS DataBase Reference 126-30-7(CAS DataBase Reference) NIST Chemistry Reference 1,3-Propanediol, 2,2-dimethyl-(126-30-7) EPA Substance Registry System Neopentyl glycol (126-30-7)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38-36-41 Safety Statements  26-36-39 WGK Germany  1 RTECS  TY5775000 F  3 Autoignition Temperature 750 °F TSCA  Yes HS Code  29053990 Hazardous Substances Data 126-30-7(Hazardous Substances Data) MSDS Information Provider Language SigmaAldrich English ACROS English ALFA English   2,2-Dimethyl-1,3-propanediol Usage And Synthesis Chemical Structure The chemical formula for Neopentyl glycol (NPG) is C5H12O2, and it is a propane-1,3-diol carrying two methyl groups at position 2.Neopentyl glycol is soluble in water, benzene, chloroform, and very soluble in ethanol and diethyl ether. Neopentylglycol (NPG) is a unique polyalcohol offering superior performance advantages in many end-use applications due to its high chemical and thermal stability. It is a unique diol offering superior performance advantages in many end-use applications. These advantages are derived from its chemical structure. The location of the hydroxyl groups on primary carbon atoms allows rapid esterification. Additionally, the two methyl groups, instead of the usual two hydrogen atoms, on the alpha carbon atom are responsible for the high chemical and thermal stability of Neopentylglycol and its derivatives. Application Neopentyl glycol is used in the synthesis of polyesters, paints, lubricants, and plasticizers. When used in the manufacture of polyesters, it enhances the stability of the product towards heat, light, and water. By esterification reaction with fatty or carboxylic acids, synthetic lubricating esters with reduced potential for oxidation or hydrolysis, compared to natural esters, can be produced. NPG is used primarily in base resins for coatings. In powder coating formulations, Neopentylglycol offers the additional advantage of providing small differences between the glass transition temperature and melting point. Important areas of application include general metal, appliance, metal furniture, automotive and machinery coatings. Important uses are also found in hydraulic fluids, synthetic lubricant oils, greases, metalworking fluids and aircraft engine lubricants. Other outlets include textiles, pharmaceuticals, pesticides, plasticizers and petroleum. High quality NPG is shipped as flake, molten and slurry. The high-quality NPG is the component in polyester resins for industrial coatings and fiberglass-reinforced plastics applications, and most polyester resin formulations contain NPG as the sole glycol component, or it is used in conjunction with a modifying glycol to achieve desired properties. NPG is also used in polyester polyols for polyurethane coatings for the automotive, industrial maintenance, transportation, and aerospace markets. Chemical Properties white solid Uses NPG Glycol is used in the synthesis of tetraphenylporphyrins. Also used in the synthesis of Bryostatin 2, a protein kinase modulator. Uses In the manufacture of plasticizers, polyesters, as modifier of alkyd resins. Uses 2,2-Dimethyl-1,3-propanediol may be used in the synthesis of: 2,2-dimethyl-1,3-propanediol cyclic phosphorochloridate 2,2-dimethyl-1,3-propanediol cyclic phenylphosphonate [1′,3′-(2′,2′-dimethylpropylene)]-2-iodo-3-octyl-5-thienylboronate cyclic carbonate 2,2-dimethyl-1,3-propanediol bis(cyclic-2,2-dimethyltrimethylene phosphite) General Description White crystalline solid. Melting point 130°C. Air & Water Reactions Soluble in water. Reactivity Profile 2,2-Dimethyl-1,3-propanediol may generate toxic gases in combination of with alkali metals, nitrides, and strong reducing agents. Reacts with inorganic acids and carboxylic acids to form esters plus water. Converted to aldehydes or acids by oxidizing agents. May initiate the polymerization of isocyanates and epoxides. Health Hazard May be harmful by ingestion or skin absorption. Causes eye and skin irritation. Material is irritating to mucous membrane and upper respiratory tract. INHALATION: Call for medical aid. Remove to fresh air. If breathing has stopped, give artificial respiration. If breathing is difficult, give oxygen. Fire Hazard Special Hazards of Combustion Products: Emits toxic fumes under fire condition. Purification Methods Crystallise the diol from *benzene or acetone/water (1:1). [Beilstein 1 IV 2551.]   2,2-Dimethyl-1,3-propanediol Preparation Products And Raw materials Raw materials Isobutyraldehyde-->Sodium formate-->Pivaldehyde Preparation Products Sodium formate-->Triethylene glycol dimethacrylate-->Unsaturated polyester resin-->3-FLUORO-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE-->2-CHLORO-6-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE-->2-BROMO-6-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE-->4-(TRIFLUOROMETHYL)-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE-->3-METHOXY-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE-->4-CHLORO-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE-->2-METHOXY-6-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE-->5-(TRIFLUOROMETHYL)-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE-->2-(3-CHLOROPROPYL)-2,5,5-TRIMETHYL-[1,3]-DIOXANE-->2-(TRIFLUOROMETHYL)-6-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE-->2-CYANO-5-BROMOPHENYLBORONIC ACID PINACOL ESTER-->3,3-DIMETHYLCYCLOBUTANECARBOXYLIC ACID-->Ibuprofen-->ISOQUINOLINE-4-BORONIC ACID 2,2-DIMETHYLPROPANEDIOL-1,3 CYCLIC ESTER

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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2,2-Dimethyl-1,3-propanediol Basic information Chemical Structure Application Product Name: 2,2-Dimethyl-1,3-propanediol Synonyms: 1,3-Dihydroxy-2,2-dimethylpropane;1,3-propanediol,2,2-dimethyl-;2,2-Dimethyl-1,3-dihydroxypropane;NEOPENTYL GLYCO;2,2-DIMETHYL-1,3-PROPANEDIOL (NPG);2,2-Dimethyl-1,3 propandiol;2,2-dimethyl-1,3-propanediol (Neopentyl Glycol);2,2-Dimethylpropan-1,3-diol CAS: 126-30-7 MF: C5H12O2 MW: 104.15 EINECS: 204-781-0 Product Categories: Organics;Intermediates of Dyes and Pigments;Pyridines Mol File: 126-30-7.mol   2,2-Dimethyl-1,3-propanediol Chemical Properties Melting point  126-128 °C Boiling point  208 °C density  1.06 vapor density  3.6 (vs air) vapor pressure  <0.8 mm Hg ( 20 °C) refractive index  1.4406 (estimate) Fp  107 °C storage temp.  Inert atmosphere,Room Temperature solubility  830g/l pka 14.57±0.10(Predicted) form  Crystalline Chunks color  White explosive limit 1.34%, 149°F Water Solubility  830 g/L (20 ºC) Sensitive  Hygroscopic Merck  14,6458 BRN  605291 Stability: Stable. Incompatible with strong oxidizing agents, acetic anhydride, acid chlorides, moisture. Combustible. CAS DataBase Reference 126-30-7(CAS DataBase Reference) NIST Chemistry Reference 1,3-Propanediol, 2,2-dimethyl-(126-30-7) EPA Substance Registry System Neopentyl glycol (126-30-7)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38-36-41 Safety Statements  26-36-39 WGK Germany  1 RTECS  TY5775000 F  3 Autoignition Temperature 750 °F TSCA  Yes HS Code  29053990 Hazardous Substances Data 126-30-7(Hazardous Substances Data) MSDS Information Provider Language SigmaAldrich English ACROS English ALFA English   2,2-Dimethyl-1,3-propanediol Usage And Synthesis Chemical Structure The chemical formula for Neopentyl glycol (NPG) is C5H12O2, and it is a propane-1,3-diol carrying two methyl groups at position 2.Neopentyl glycol is soluble in water, benzene, chloroform, and very soluble in ethanol and diethyl ether. Neopentylglycol (NPG) is a unique polyalcohol offering superior performance advantages in many end-use applications due to its high chemical and thermal stability. It is a unique diol offering superior performance advantages in many end-use applications. These advantages are derived from its chemical structure. The location of the hydroxyl groups on primary carbon atoms allows rapid esterification. Additionally, the two methyl groups, instead of the usual two hydrogen atoms, on the alpha carbon atom are responsible for the high chemical and thermal stability of Neopentylglycol and its derivatives. Application Neopentyl glycol is used in the synthesis of polyesters, paints, lubricants, and plasticizers. When used in the manufacture of polyesters, it enhances the stability of the product towards heat, light, and water. By esterification reaction with fatty or carboxylic acids, synthetic lubricating esters with reduced potential for oxidation or hydrolysis, compared to natural esters, can be produced. NPG is used primarily in base resins for coatings. In powder coating formulations, Neopentylglycol offers the additional advantage of providing small differences between the glass transition temperature and melting point. Important areas of application include general metal, appliance, metal furniture, automotive and machinery coatings. Important uses are also found in hydraulic fluids, synthetic lubricant oils, greases, metalworking fluids and aircraft engine lubricants. Other outlets include textiles, pharmaceuticals, pesticides, plasticizers and petroleum. High quality NPG is shipped as flake, molten and slurry. The high-quality NPG is the component in polyester resins for industrial coatings and fiberglass-reinforced plastics applications, and most polyester resin formulations contain NPG as the sole glycol component, or it is used in conjunction with a modifying glycol to achieve desired properties. NPG is also used in polyester polyols for polyurethane coatings for the automotive, industrial maintenance, transportation, and aerospace markets. Chemical Properties white solid Uses NPG Glycol is used in the synthesis of tetraphenylporphyrins. Also used in the synthesis of Bryostatin 2, a protein kinase modulator. Uses In the manufacture of plasticizers, polyesters, as modifier of alkyd resins. Uses 2,2-Dimethyl-1,3-propanediol may be used in the synthesis of: 2,2-dimethyl-1,3-propanediol cyclic phosphorochloridate 2,2-dimethyl-1,3-propanediol cyclic phenylphosphonate [1′,3′-(2′,2′-dimethylpropylene)]-2-iodo-3-octyl-5-thienylboronate cyclic carbonate 2,2-dimethyl-1,3-propanediol bis(cyclic-2,2-dimethyltrimethylene phosphite) General Description White crystalline solid. Melting point 130°C. Air & Water Reactions Soluble in water. Reactivity Profile 2,2-Dimethyl-1,3-propanediol may generate toxic gases in combination of with alkali metals, nitrides, and strong reducing agents. Reacts with inorganic acids and carboxylic acids to form esters plus water. Converted to aldehydes or acids by oxidizing agents. May initiate the polymerization of isocyanates and epoxides. Health Hazard May be harmful by ingestion or skin absorption. Causes eye and skin irritation. Material is irritating to mucous membrane and upper respiratory tract. INHALATION: Call for medical aid. Remove to fresh air. If breathing has stopped, give artificial respiration. If breathing is difficult, give oxygen. Fire Hazard Special Hazards of Combustion Products: Emits toxic fumes under fire condition. Purification Methods Crystallise the diol from *benzene or acetone/water (1:1). [Beilstein 1 IV 2551.]   2,2-Dimethyl-1,3-propanediol Preparation Products And Raw materials Raw materials Isobutyraldehyde-->Sodium formate-->Pivaldehyde Preparation Products Sodium formate-->Triethylene glycol dimethacrylate-->Unsaturated polyester resin-->3-FLUORO-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE-->2-CHLORO-6-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE-->2-BROMO-6-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE-->4-(TRIFLUOROMETHYL)-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE-->3-METHOXY-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE-->4-CHLORO-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE-->2-METHOXY-6-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE-->5-(TRIFLUOROMETHYL)-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE-->2-(3-CHLOROPROPYL)-2,5,5-TRIMETHYL-[1,3]-DIOXANE-->2-(TRIFLUOROMETHYL)-6-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE-->2-CYANO-5-BROMOPHENYLBORONIC ACID PINACOL ESTER-->3,3-DIMETHYLCYCLOBUTANECARBOXYLIC ACID-->Ibuprofen-->ISOQUINOLINE-4-BORONIC ACID 2,2-DIMETHYLPROPANEDIOL-1,3 CYCLIC ESTER