China Largest Manufacturer factory sales Shikimic Acid CAS 138-59-0 CAS NO.138-59-0

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Shikimic acid Basic information Product Name: Shikimic acid Synonyms: L-SHIKIMIC ACID;(3R,4S,5R)-3,4,5-TRIHYDROXY-1-CYCLOHEXENECARBOXYLIC ACID;(3R,4S,5R)-3,4,5-TRIHYDROXY-CYCLOHEX-1-ENECARBOXYLIC ACID;Shikimic acid,(3R,4S,5R)-()-3,4,5-Trihydroxy-1-cyclohexenecarboxylic acid;Illicium Verum P.E.;Shikimic acid methyl esther;ShikiMic acid, 98% 1GR;3,4,5-Trihydroxycyclohex-1-enecarboxylic acid CAS: 138-59-0 MF: C7H10O5 MW: 174.15 EINECS: 205-334-2 Product Categories: Inhibitors;Plant Extract;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;Chiral Reagents;Chiral Building Blocks;Simple Alcohols (Chiral);Synthetic Organic Chemistry;Natural Plant Extract;API;standardized herbal extract;Antibiotic;API intermediates Mol File: 138-59-0.mol   Shikimic acid Chemical Properties Melting point  185-187 °C (lit.) alpha  -180 º (c=4, H2O 25 ºC) Boiling point  225.11°C (rough estimate) density  1.52 g/cm3 (27.2℃) refractive index  -180 ° (C=1, H2O) storage temp.  2-8°C solubility  180g/l pka pK (14.1°) 5.19 form  Powder color  White to light beige or light gray optical activity [α]/D -180.0±5.0°, c = 4 in H2O Water Solubility  18 g/100 mL (20 ºC) Sensitive  Hygroscopic Merck  14,8480 BRN  4782717 InChIKey JXOHGGNKMLTUBP-HSUXUTPPSA-N CAS DataBase Reference 138-59-0(CAS DataBase Reference) IARC 3 (Vol. 40, Sup 7) 1987 NIST Chemistry Reference Shikimic acid(138-59-0)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  22-24/25-36-26 WGK Germany  3 RTECS  GW4600000 F  3-10 HS Code  29181980 Hazardous Substances Data 138-59-0(Hazardous Substances Data) Toxicity LD5 i.p. in mice: 1000 mg/kg (Evans, Osman) MSDS Information Provider Language Shikimic acid English SigmaAldrich English ACROS English ALFA English   Shikimic acid Usage And Synthesis Chemical Properties White Solid Uses Naturally occurring (-)-form is a major biosynthetic precursor of phenylalanine, tyrosine, and tryptophan and hence of the majority of plant alkaloids. It is also involved in the biosynthesis of lignin, flavonpids and other important aromatic compounds. Uses Shikimic acid has been used as a standard for the quantification of shikimate in apical parts of roots. It has also been used as a substrate in shikimate kinase assay. Definition ChEBI: A cyclohexenecarboxylic acid that is cyclohex-1-ene-1-carboxylic acid substituted by hydroxy groups at positions 3, 4 and 5 (the 3R,4S,5R stereoisomer). It is an intermediate metabolite in plants and micro rganisms. Biochem/physiol Actions Shikimic acid is observed to be carcinogenic in rat models, when administered. It serves as a precursor for the biosynthesis of aromatic amino acids, alkaloids and other aromatic metabolites in microorganisms. Shikimic acid is known to inhibit adenosine diphosphate (ADP) induced platelet aggregation and blood coagulation in rabbits.   Shikimic acid Preparation Products And Raw materials Preparation Products Ethyl 3,4-O-isopropylideneshikiMate-->ShikiMic Acid Ethyl Ester-->CHORISMIC ACID

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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Shikimic acid Basic information Product Name: Shikimic acid Synonyms: L-SHIKIMIC ACID;(3R,4S,5R)-3,4,5-TRIHYDROXY-1-CYCLOHEXENECARBOXYLIC ACID;(3R,4S,5R)-3,4,5-TRIHYDROXY-CYCLOHEX-1-ENECARBOXYLIC ACID;Shikimic acid,(3R,4S,5R)-()-3,4,5-Trihydroxy-1-cyclohexenecarboxylic acid;Illicium Verum P.E.;Shikimic acid methyl esther;ShikiMic acid, 98% 1GR;3,4,5-Trihydroxycyclohex-1-enecarboxylic acid CAS: 138-59-0 MF: C7H10O5 MW: 174.15 EINECS: 205-334-2 Product Categories: Inhibitors;Plant Extract;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;Chiral Reagents;Chiral Building Blocks;Simple Alcohols (Chiral);Synthetic Organic Chemistry;Natural Plant Extract;API;standardized herbal extract;Antibiotic;API intermediates Mol File: 138-59-0.mol   Shikimic acid Chemical Properties Melting point  185-187 °C (lit.) alpha  -180 º (c=4, H2O 25 ºC) Boiling point  225.11°C (rough estimate) density  1.52 g/cm3 (27.2℃) refractive index  -180 ° (C=1, H2O) storage temp.  2-8°C solubility  180g/l pka pK (14.1°) 5.19 form  Powder color  White to light beige or light gray optical activity [α]/D -180.0±5.0°, c = 4 in H2O Water Solubility  18 g/100 mL (20 ºC) Sensitive  Hygroscopic Merck  14,8480 BRN  4782717 InChIKey JXOHGGNKMLTUBP-HSUXUTPPSA-N CAS DataBase Reference 138-59-0(CAS DataBase Reference) IARC 3 (Vol. 40, Sup 7) 1987 NIST Chemistry Reference Shikimic acid(138-59-0)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  22-24/25-36-26 WGK Germany  3 RTECS  GW4600000 F  3-10 HS Code  29181980 Hazardous Substances Data 138-59-0(Hazardous Substances Data) Toxicity LD5 i.p. in mice: 1000 mg/kg (Evans, Osman) MSDS Information Provider Language Shikimic acid English SigmaAldrich English ACROS English ALFA English   Shikimic acid Usage And Synthesis Chemical Properties White Solid Uses Naturally occurring (-)-form is a major biosynthetic precursor of phenylalanine, tyrosine, and tryptophan and hence of the majority of plant alkaloids. It is also involved in the biosynthesis of lignin, flavonpids and other important aromatic compounds. Uses Shikimic acid has been used as a standard for the quantification of shikimate in apical parts of roots. It has also been used as a substrate in shikimate kinase assay. Definition ChEBI: A cyclohexenecarboxylic acid that is cyclohex-1-ene-1-carboxylic acid substituted by hydroxy groups at positions 3, 4 and 5 (the 3R,4S,5R stereoisomer). It is an intermediate metabolite in plants and micro rganisms. Biochem/physiol Actions Shikimic acid is observed to be carcinogenic in rat models, when administered. It serves as a precursor for the biosynthesis of aromatic amino acids, alkaloids and other aromatic metabolites in microorganisms. Shikimic acid is known to inhibit adenosine diphosphate (ADP) induced platelet aggregation and blood coagulation in rabbits.   Shikimic acid Preparation Products And Raw materials Preparation Products Ethyl 3,4-O-isopropylideneshikiMate-->ShikiMic Acid Ethyl Ester-->CHORISMIC ACID