China Largest Manufacturer factory sales Chitin CAS 1398-61-4 CAS NO.1398-61-4

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Chitin Basic information Description Chemical structure Source applications Preparation Product Name: Chitin Synonyms: BETA-(1,4)-2-ACETAMIDO-2-DEOXY-D-GLUCOSE;BETA-(1,4)-2-AMINO-2-DEOXY-D-GLUCOSE;CHITOSAN, DEACETYLATED;POLY-(B1-4)-N-ACETYL-GLUCOSAMINE;CHITINMICROPARTICLES;Chitin (powder);POLY-[1->4]-BETA-N-ACETYL-D-GLUCOSAMINE;POLY(D-GLUCOSAMINE) CAS: 1398-61-4 MF: C6H11NO4X2 MW: 161.16 EINECS: 215-744-3 Product Categories: Sugars, Carbohydrates & Glucosides;Biochemistry;Polysaccharides;Sugars;Dextrins、Sugar & Carbohydrates;Oligosaccharides;Biochemicals and Reagents;Carbohydrate;Carbohydrates;Carbohydrates A to Z;Carbohydrates A-C;Chitin;Chitosan and Chitin;Materials Science;Oligosaccharide Compounds;Metabolic Pathways;Metabolites and Cofactors on the Metabolic Pathways Chart;Metabolomics;Natural Polymers;Polymer Science;Polymers;Polysaccharide;Fiber and Prebiotics;Functional Foods;Insoluble Fiber;Nutrition Research Mol File: 1398-61-4.mol   Chitin Chemical Properties Melting point  >300°C (dec.) Boiling point  737.18°C (rough estimate) density  1.3744 (rough estimate) refractive index  1.6000 (estimate) storage temp.  Room Temp solubility  dilute aqueous acid (pH <6.5).: soluble form  purified powder color  White Water Solubility  insoluble Merck  14,2065 Stability: Stable. Incompatible with strong oxidizing agents. EPA Substance Registry System Chitin (1398-61-4)   Safety Information Hazard Codes  Xi,Xn Risk Statements  20/21/22-36/37/38 Safety Statements  24/25-36-26 WGK Germany  3 RTECS  FM6300000 F  3 TSCA  Yes HS Code  32139000 Hazardous Substances Data 1398-61-4(Hazardous Substances Data) MSDS Information Provider Language Chitin English SigmaAldrich English ACROS English   Chitin Usage And Synthesis Description Chitin is a naturally occurring polysaccharide found in the shells of living organisms such as crabs, lobsters, tortoise, shrimps, and insects or it can be generated via fungal fermentation processes. And chitosan is a unique biobased polymer that is a derivative of chitin and forms the exoskeleton of arthropods. It is obtained by partial deacetylation of chitin using a chemical method or by enzymatic hydrolysis. In general, chitin with a degree of deacetylation of 70% or above is considered to be chitosan. Chemical structure Chitin is a naturally occurring polymer consisting of 2-acetamido-2- deoxy-D-glucose via a β(1-4) linkage. Three forms of chitin are available, namely α-, β-, and γ-chitin, however, the structure of α-chitin has been investigated more extensively than that of either the β- or γ- form. Very few studies have been carried out on γ-chitin because γ-chitin may be a distorted version of either α- or β-chitin. Its structure is similar to cellulose but with 2-acetamido-2-deoxy-β-D-glucose (NAG) monomer units. Chitin has limited applications because of its acetyl groups, but through the deacetylation process chitin is converted into chitosan. During the deacetylation process, the acetyl group present in chitin is converted into hydroxyl (-OH) and amino (-NH2) groups in the chitosan. The modification of the reactive functional groups present in chitosan opens the possibility of broad application in many fields. Source Chitin is usually isolated from the exoskeletons of arthropods’ chitin-based tissue (30%-40% protein, 30%-50% calcium carbonate, and 20%-30% chitin), such as crustaceans, mollusks, insects, and certain fungi. It is a biological nanocomposite material strictly hierarchically organized which reveals various structural levels. At the molecular level is the polysaccharide chitin itself. The next structural level is the arrangement of c. 18-25 of such molecules in the form of narrow and long crystalline units, which are wrapped by proteins, forming nanofibrils of about 2-5 nm diameter and about 300 nm length. The next step in the scale consists of the clustering of some of these nanofibrils into long chitin-protein fibers of about 50-300 nm diameter. Chitin is mainly occurs in three different polymeric α-, β-, and γ-forms. The chains are arranged in stacks or sheets in α-chitin and adjacent sheets along the c-axis have the same direction in a parallel arrangement. The α-chitin occurs in the exoskeletons of crustaceans (e.g., crabs, lobsters, and prawns). In the case of β-chitin, the adjacent sheets along the c-axis present in opposite directions in an antiparallel arrangement and it can be found in squid pen, certain diatoms, and vestimentiferans (a class of deep-sea animal). However every third sheet is in the opposite direction to the preceding sheets in γ-chitin. It mainly exists in fungi and yeast. applications Chitin and its derivative chitosan are natural biopolymers which are extracted from crabs, prawns, and shrimps. Chitin consists of β-(1,4)- linked 2-acetamido-2 deoxy-β-D-glucose which is insoluble in water and hydrophobic in nature. Chitin is a natural biopolymer, which is biocompatible and biodegradable and useful in many applications like biomedical, electronics, photography, and textiles. The main advantages of chitin and its derivates are the low cost and easily availability. The chitin-based composites like chitin beads, chitin nanofibers, and chitin hydrogels are used in drug delivery and tissue engineering applications. In recent times, chitin and its derivates have gained much importance in the field of electronic applications as sensors and energy storage applications. Chitin nanofiber papers are being used as flexible green electronics in solar cells and organic light-emitting diodes. Aksoy et al. prepared low-cost chitin derivatives with high conductivity, for the construction of Schottky diodes, which are useful for photoelectrical applications. Schauer et al. reported a variation of the piezoelectric effect of the chitin electrospun nanofibers. Preparation Chitin (C8H13O5N)n, is derived from the Greek word “chiton,” meaning a coat of mail. It is a natural polysaccharide of β-(1-4)-N-acetyl-D-glucosamine monomers, first identified by the chemist Henri Braconnot in 1811. A suspension of chitin crystallite particles was first prepared by Marchessault et al. in 1959. In this method, 2.5 N hydrochloric acid solution was used to treat purified chitin under reflux for 1 h. After the reflux, the excess acid was separated by a decantation process and then distilled water was added to obtain the suspension. It was observed from their method that the acid-hydrolyzed chitin spontaneously dispersed into rod-like particles that could be concentrated to a liquid crystalline phase and self-assembled to a cholesteric liquid crystalline phase above a certain concentration. Though chitins are present within numerous taxonomic groups, on the commercial scale they are usually extracted from marine crustaceans, mainly because a large amount of waste is available as a by-product of food processing. Description Chitin is the most abundant natural amino polysaccharide. It has a similar annual yield as cellulose. Chitin is a kind of highly valuable material in biomedical applications because of its high biocompatibility, biodegradability and non-toxicity as well as its antimicrobial activity and low immunogenicity. It can be easily processed into gels, membrane, nanofibers, beads, nanoparticle, scaffold and sponges, enables its wide applications. In the tissue engineering, it can be used for manufacturing polymer scaffold to satisfy the demands of repairing, replacing, maintaining, or enhancing the function of a particular tissue or organ. In wound dressing, chitin can be used as antimicrobial reagent. In the field of drug delivery, the water-soluble carboxymethyl chitin (CMC) nanoparticle can be used as an effective carrier in drug delivery. Chemical Properties Chitin is a colorless, crystalline or amorphous powder that is insoluble in water, organic solvents, dilute acids, and alkalis. It dissolves in concentrated mineral acids with simultaneous degradation of the polymer. Although chitosan is insoluble in water, it does dissolve in aqueous organic acids, for example, acetic and formic acids, as well as inorganic acids. Chitin and chitosan preparation can vary due to the source, with compositional differences. Similarly, the physicochemical characteristics of chitin and chitosan differ between crustacean species and preparation methods. Several studies have clearly demonstrated the specific characteristics of these products. The Mw and degree of deacetylation (DD) vary with process conditions. The physicochemical characteristics of chitin and chitosan influence their functional properties. Mw and DD vary with process conditions or different extraction methods. Chitosan's application depends on physical, biological, and chemical properties and chitosan depends on two parameters, such as DD and Mw. Uses Chitin, a β(1,4) polymer chain of N-acetyl-D glucosamine, is used as a substrate to identify, differentiate and characterize chitinase(s) and chitin deacetylase(s). Chitin may be used as a viscosity/thickening agent or binder. Uses chitin (chitine) is a moisture retainer and film-forming agent. This is a naturally occurring polysaccharide found in the shells of crustaceans, such as shrimp and crab, as well as in some fungi and algae. Uses A naturally occuring fibre found in the shells of shellfish. Used for the analysis of chitinase. lysozyme substrate. Definition chitin: A polysaccharide comprisingchains of N-acetyl-d-glucosamine,a derivative of glucose. Chitin isstructurally very similar to celluloseand serves to strengthen the supportingstructures of various invertebrates.It also occurs in fungi. Agricultural Uses Chitin is a polysaccharidec omprising chains of N-acetyl- D-glucosamine, a derivative of glucose, linked byβ-1,4 bonds and containing about 77 nitrogen atoms. It may be visualized as cellulose in which the hydroxyl groups on the second carbon are replaced by -NHCOCH3 groups Chitin is structurally very similar to cellulose and serves to strengthen various invertebrates. It offers resistance to chemicals and is present in the cell wall of some fungi as well as in the exoskeleton of insects. References Kumar, Majeti NV Ravi. "A review of chitin and chitosan applications." Reactive and functional polymers 46.1 (2000): 1-27. Jayakumar, R., et al. "Biomedical applications of chitin and chitosan based nanomaterials—A short review." Carbohydrate Polymers 82.2 (2010): 227-232.   Chitin Preparation Products And Raw materials Raw materials Sodium hydroxide-->Sodium borohydride-->Potassium permanganate-->Calcium carbonate-->Sodium bisulfite-->Potassium hydroxide solution-->Α-PROTEIN-->Chitosan Preparation Products Sodium carboxymethyl cellulose-->Chitosan-->adhesive FD-->adhesive 750-->Adhesive 707-->Glucosamine

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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Product Name:	Chitin
Synonyms:	BETA-(1,4)-2-ACETAMIDO-2-DEOXY-D-GLUCOSE;BETA-(1,4)-2-AMINO-2-DEOXY-D-GLUCOSE;CHITOSAN, DEACETYLATED;POLY-(B1-4)-N-ACETYL-GLUCOSAMINE;CHITINMICROPARTICLES;Chitin (powder);POLY-[1->4]-BETA-N-ACETYL-D-GLUCOSAMINE;POLY(D-GLUCOSAMINE)
CAS:	1398-61-4
MF:	C6H11NO4X2
MW:	161.16
EINECS:	215-744-3
Product Categories:	Sugars, Carbohydrates & Glucosides;Biochemistry;Polysaccharides;Sugars;Dextrins、Sugar & Carbohydrates;Oligosaccharides;Biochemicals and Reagents;Carbohydrate;Carbohydrates;Carbohydrates A to Z;Carbohydrates A-C;Chitin;Chitosan and Chitin;Materials Science;Oligosaccharide Compounds;Metabolic Pathways;Metabolites and Cofactors on the Metabolic Pathways Chart;Metabolomics;Natural Polymers;Polymer Science;Polymers;Polysaccharide;Fiber and Prebiotics;Functional Foods;Insoluble Fiber;Nutrition Research
Mol File:	1398-61-4.mol

Description	Chitin is a naturally occurring polysaccharide found in the shells of living organisms such as crabs, lobsters, tortoise, shrimps, and insects or it can be generated via fungal fermentation processes. And chitosan is a unique biobased polymer that is a derivative of chitin and forms the exoskeleton of arthropods. It is obtained by partial deacetylation of chitin using a chemical method or by enzymatic hydrolysis. In general, chitin with a degree of deacetylation of 70% or above is considered to be chitosan.
Chemical structure	Chitin is a naturally occurring polymer consisting of 2-acetamido-2- deoxy-D-glucose via a β(1-4) linkage. Three forms of chitin are available, namely α-, β-, and γ-chitin, however, the structure of α-chitin has been investigated more extensively than that of either the β- or γ- form. Very few studies have been carried out on γ-chitin because γ-chitin may be a distorted version of either α- or β-chitin. Its structure is similar to cellulose but with 2-acetamido-2-deoxy-β-D-glucose (NAG) monomer units. Chitin has limited applications because of its acetyl groups, but through the deacetylation process chitin is converted into chitosan. During the deacetylation process, the acetyl group present in chitin is converted into hydroxyl (-OH) and amino (-NH2) groups in the chitosan. The modification of the reactive functional groups present in chitosan opens the possibility of broad application in many fields.
Source	Chitin is usually isolated from the exoskeletons of arthropods’ chitin-based tissue (30%-40% protein, 30%-50% calcium carbonate, and 20%-30% chitin), such as crustaceans, mollusks, insects, and certain fungi. It is a biological nanocomposite material strictly hierarchically organized which reveals various structural levels. At the molecular level is the polysaccharide chitin itself. The next structural level is the arrangement of c. 18-25 of such molecules in the form of narrow and long crystalline units, which are wrapped by proteins, forming nanofibrils of about 2-5 nm diameter and about 300 nm length. The next step in the scale consists of the clustering of some of these nanofibrils into long chitin-protein fibers of about 50-300 nm diameter. Chitin is mainly occurs in three different polymeric α-, β-, and γ-forms. The chains are arranged in stacks or sheets in α-chitin and adjacent sheets along the c-axis have the same direction in a parallel arrangement. The α-chitin occurs in the exoskeletons of crustaceans (e.g., crabs, lobsters, and prawns). In the case of β-chitin, the adjacent sheets along the c-axis present in opposite directions in an antiparallel arrangement and it can be found in squid pen, certain diatoms, and vestimentiferans (a class of deep-sea animal). However every third sheet is in the opposite direction to the preceding sheets in γ-chitin. It mainly exists in fungi and yeast.
applications	Chitin and its derivative chitosan are natural biopolymers which are extracted from crabs, prawns, and shrimps. Chitin consists of β-(1,4)- linked 2-acetamido-2 deoxy-β-D-glucose which is insoluble in water and hydrophobic in nature. Chitin is a natural biopolymer, which is biocompatible and biodegradable and useful in many applications like biomedical, electronics, photography, and textiles. The main advantages of chitin and its derivates are the low cost and easily availability. The chitin-based composites like chitin beads, chitin nanofibers, and chitin hydrogels are used in drug delivery and tissue engineering applications. In recent times, chitin and its derivates have gained much importance in the field of electronic applications as sensors and energy storage applications. Chitin nanofiber papers are being used as flexible green electronics in solar cells and organic light-emitting diodes. Aksoy et al. prepared low-cost chitin derivatives with high conductivity, for the construction of Schottky diodes, which are useful for photoelectrical applications. Schauer et al. reported a variation of the piezoelectric effect of the chitin electrospun nanofibers.
Preparation	Chitin (C8H13O5N)n, is derived from the Greek word “chiton,” meaning a coat of mail. It is a natural polysaccharide of β-(1-4)-N-acetyl-D-glucosamine monomers, first identified by the chemist Henri Braconnot in 1811. A suspension of chitin crystallite particles was first prepared by Marchessault et al. in 1959. In this method, 2.5 N hydrochloric acid solution was used to treat purified chitin under reflux for 1 h. After the reflux, the excess acid was separated by a decantation process and then distilled water was added to obtain the suspension. It was observed from their method that the acid-hydrolyzed chitin spontaneously dispersed into rod-like particles that could be concentrated to a liquid crystalline phase and self-assembled to a cholesteric liquid crystalline phase above a certain concentration. Though chitins are present within numerous taxonomic groups, on the commercial scale they are usually extracted from marine crustaceans, mainly because a large amount of waste is available as a by-product of food processing.
Description	Chitin is the most abundant natural amino polysaccharide. It has a similar annual yield as cellulose. Chitin is a kind of highly valuable material in biomedical applications because of its high biocompatibility, biodegradability and non-toxicity as well as its antimicrobial activity and low immunogenicity. It can be easily processed into gels, membrane, nanofibers, beads, nanoparticle, scaffold and sponges, enables its wide applications. In the tissue engineering, it can be used for manufacturing polymer scaffold to satisfy the demands of repairing, replacing, maintaining, or enhancing the function of a particular tissue or organ. In wound dressing, chitin can be used as antimicrobial reagent. In the field of drug delivery, the water-soluble carboxymethyl chitin (CMC) nanoparticle can be used as an effective carrier in drug delivery.
Chemical Properties	Chitin is a colorless, crystalline or amorphous powder that is insoluble in water, organic solvents, dilute acids, and alkalis. It dissolves in concentrated mineral acids with simultaneous degradation of the polymer. Although chitosan is insoluble in water, it does dissolve in aqueous organic acids, for example, acetic and formic acids, as well as inorganic acids. Chitin and chitosan preparation can vary due to the source, with compositional differences. Similarly, the physicochemical characteristics of chitin and chitosan differ between crustacean species and preparation methods. Several studies have clearly demonstrated the specific characteristics of these products. The Mw and degree of deacetylation (DD) vary with process conditions. The physicochemical characteristics of chitin and chitosan influence their functional properties. Mw and DD vary with process conditions or different extraction methods. Chitosan's application depends on physical, biological, and chemical properties and chitosan depends on two parameters, such as DD and Mw.
Uses	Chitin, a β(1,4) polymer chain of N-acetyl-D glucosamine, is used as a substrate to identify, differentiate and characterize chitinase(s) and chitin deacetylase(s). Chitin may be used as a viscosity/thickening agent or binder.
Uses	chitin (chitine) is a moisture retainer and film-forming agent. This is a naturally occurring polysaccharide found in the shells of crustaceans, such as shrimp and crab, as well as in some fungi and algae.
Uses	A naturally occuring fibre found in the shells of shellfish. Used for the analysis of chitinase. lysozyme substrate.
Definition	chitin: A polysaccharide comprisingchains of N-acetyl-d-glucosamine,a derivative of glucose. Chitin isstructurally very similar to celluloseand serves to strengthen the supportingstructures of various invertebrates.It also occurs in fungi.
Agricultural Uses	Chitin is a polysaccharidec omprising chains of N-acetyl- D-glucosamine, a derivative of glucose, linked byβ-1,4 bonds and containing about 77 nitrogen atoms. It may be visualized as cellulose in which the hydroxyl groups on the second carbon are replaced by -NHCOCH3 groups Chitin is structurally very similar to cellulose and serves to strengthen various invertebrates. It offers resistance to chemicals and is present in the cell wall of some fungi as well as in the exoskeleton of insects.
References	Kumar, Majeti NV Ravi. "A review of chitin and chitosan applications." Reactive and functional polymers 46.1 (2000): 1-27. Jayakumar, R., et al. "Biomedical applications of chitin and chitosan based nanomaterials—A short review." Carbohydrate Polymers 82.2 (2010): 227-232.