China Largest Manufacturer factory sales Trans-Cinnamic acid CAS 140-10-3 CAS NO.140-10-3

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trans-Cinnamic acid Basic information Product Name: trans-Cinnamic acid Synonyms: (e)-2-propenoicaci;(E)-3-Phenyl-2-propenoic acid;Nat.trans-Cinnamic acid;trans-Cinnamicacid 140-10-3;trans-Cinnamic acid, AR,99%;trans-Cinnamic acid, CP,98%;CINNAMIC ACID, TRANS-(SG);trans-Ciamic acid CAS: 140-10-3 MF: C9H8O2 MW: 148.16 EINECS: 205-398-1 Product Categories: Highly Purified Reagents;Proteomics;s wort);Vaccinium myrtillus (Bilberry);chemical reagent;Inhibitors;Analytical Chemistry;Auxins;Biochemistry;Mass Spectrometry;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Pharmaceutical Intermediates;Benzene derivatives;Aromatic Cinnamic Acids, Esters and Derivatives;Matrix Materials (MALDI-TOF-MS);Plant Growth Regulators;Matrices for MALDI Analysis;Aloe Vera;Aspalathus linearis (Rooibos tea);Building Blocks;C9;Carbonyl Compounds;Carboxylic Acids;Chemical Synthesis;Citrus aurantium (Seville orange);Curcuma longa (Turmeric);Hypericum perforatum (St John′;Other Categories;Zone Refined Products;Nutrition Research;Ocimum basilicum (Basil);Organic Building Blocks;Panax ginseng;Phytochemicals by Plant (Food/Spice/Herb);Piper methysticum (Kava);VX:15689727968;140-10-3 Mol File: 140-10-3.mol   trans-Cinnamic acid Chemical Properties Melting point  133 °C (lit.) Boiling point  300 °C(lit.) density  1.248 vapor pressure  1.3 hPa (128 °C) refractive index  1.5049 (estimate) Fp  >230 °F storage temp.  2-8°C solubility  0.4g/l pka 4.44(at 25℃) form  Crystalline Powder color  White to almost white Specific Gravity 0.91 Odor Faint odour PH 3-4 (0.4g/l, H2O, 20℃) PH Range 3 - 4 Water Solubility  0.4 g/L (20 ºC) λmax 273nm(MeOH)(lit.) Merck  14,2299 BRN  1905952 InChIKey WBYWAXJHAXSJNI-VOTSOKGWSA-N CAS DataBase Reference 140-10-3(CAS DataBase Reference) NIST Chemistry Reference Cinnamic acid(140-10-3) EPA Substance Registry System (E)-Cinnamic acid (140-10-3)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  26-36-37/39 WGK Germany  1 RTECS  GD7850000 TSCA  Yes HS Code  29163900 Toxicity LD50 orally in Rabbit: 2500 mg/kg LD50 dermal Rabbit > 5000 mg/kg MSDS Information Provider Language 3-Phenyl-2-propenoic acid English ACROS English SigmaAldrich English ALFA English   trans-Cinnamic acid Usage And Synthesis Chemical Properties White to almost white crystalline powder Uses trans-Cinnamic acid is used in flavors, synthetic indigo and pharmaceuticals. It is involved in the production of methyl, ethyl and benzyl esters, which is used in the perfume industry. It serves as a precursor to the sweetener aspartame through enzyme-catalyzed amination to phenylalanine. It is a self-inhibitor produced by fungal spores to prevent germination. In addition, it is used to establish phenolic compounds by liquid chromatography, ultraviolet and mass spectrometry. It is utilized as a potential agent, thereby preventing lung tumor cells from metastasizing. Further, it induces intracellular release of calcium ions from the vacuole to the cytoplasm in order to trigger phytotoxicity in cucumber. Uses trans-Cinnamic acid was used to establish library of phenolic compounds by liquid chromatography/ultraviolet and mass spectrometry/mass spectrometry. General Description trans-Cinnamic acid is an α,β-unsaturated aromatic acid that can be used as a flavoring agent. It is mainly used to prepare ester derivatives that are used in perfume industry. trans-Cinnamic acid is the key volatile components of cinnamon essential oil. Biochem/physiol Actions trans-cinnamic acid has inhibitory effect on phorbol-12-myristate-13-acetate-induced invasion of human lung adenocarcinoma A549 cells. It is a potential agent which can prevent lung tumor cells from metastasizing. It induces intracellular release of Ca2+ from the vacuole to the cytoplasm which triggers phytotoxicity in cucumber. Purification Methods Crystallise the acid from *benzene, CCl4, hot water, water/EtOH (3:1), or 20% aqueous EtOH. Dry it at 60o in vacuo. It is steam volatile. [Beilstein 9 IV 2002.]   trans-Cinnamic acid Preparation Products And Raw materials Raw materials Acetic anhydride Preparation Products Cinnamyl alcohol-->Phenylacetaldehyde-->cyclamen aldehyde-->alpha-Amylcinnamaldehyde-->Docetaxel-->Cinnamic acid-->Ethyl cinnamate-->3-CHLOROBENZO[B]THIOPHENE-2-CARBOXAMIDE-->3-CHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID HYDRAZIDE-->METHYL 3-CHLOROBENZO[B]THIOPHENE-2-CARBOXYLATE-->Lacidipine-->Cinnamyl cinnamate-->3-CHLOROBENZO[B]THIOPHENE-2-CARBOXYLIC ACID-->3-CHLOROBENZO[B]THIOPHENE-2-CARBONYL CHLORIDE-->Benzyl cinnamate-->ALLYL CINNAMATE-->4-Hydroxy-3-methoxystyrene-->Dihydrocoumarin-->Methyl cinnamate

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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trans-Cinnamic acid Basic information Product Name: trans-Cinnamic acid Synonyms: (e)-2-propenoicaci;(E)-3-Phenyl-2-propenoic acid;Nat.trans-Cinnamic acid;trans-Cinnamicacid 140-10-3;trans-Cinnamic acid, AR,99%;trans-Cinnamic acid, CP,98%;CINNAMIC ACID, TRANS-(SG);trans-Ciamic acid CAS: 140-10-3 MF: C9H8O2 MW: 148.16 EINECS: 205-398-1 Product Categories: Highly Purified Reagents;Proteomics;s wort);Vaccinium myrtillus (Bilberry);chemical reagent;Inhibitors;Analytical Chemistry;Auxins;Biochemistry;Mass Spectrometry;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Pharmaceutical Intermediates;Benzene derivatives;Aromatic Cinnamic Acids, Esters and Derivatives;Matrix Materials (MALDI-TOF-MS);Plant Growth Regulators;Matrices for MALDI Analysis;Aloe Vera;Aspalathus linearis (Rooibos tea);Building Blocks;C9;Carbonyl Compounds;Carboxylic Acids;Chemical Synthesis;Citrus aurantium (Seville orange);Curcuma longa (Turmeric);Hypericum perforatum (St John′;Other Categories;Zone Refined Products;Nutrition Research;Ocimum basilicum (Basil);Organic Building Blocks;Panax ginseng;Phytochemicals by Plant (Food/Spice/Herb);Piper methysticum (Kava);VX:15689727968;140-10-3 Mol File: 140-10-3.mol   trans-Cinnamic acid Chemical Properties Melting point  133 °C (lit.) Boiling point  300 °C(lit.) density  1.248 vapor pressure  1.3 hPa (128 °C) refractive index  1.5049 (estimate) Fp  >230 °F storage temp.  2-8°C solubility  0.4g/l pka 4.44(at 25℃) form  Crystalline Powder color  White to almost white Specific Gravity 0.91 Odor Faint odour PH 3-4 (0.4g/l, H2O, 20℃) PH Range 3 - 4 Water Solubility  0.4 g/L (20 ºC) λmax 273nm(MeOH)(lit.) Merck  14,2299 BRN  1905952 InChIKey WBYWAXJHAXSJNI-VOTSOKGWSA-N CAS DataBase Reference 140-10-3(CAS DataBase Reference) NIST Chemistry Reference Cinnamic acid(140-10-3) EPA Substance Registry System (E)-Cinnamic acid (140-10-3)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  26-36-37/39 WGK Germany  1 RTECS  GD7850000 TSCA  Yes HS Code  29163900 Toxicity LD50 orally in Rabbit: 2500 mg/kg LD50 dermal Rabbit > 5000 mg/kg MSDS Information Provider Language 3-Phenyl-2-propenoic acid English ACROS English SigmaAldrich English ALFA English   trans-Cinnamic acid Usage And Synthesis Chemical Properties White to almost white crystalline powder Uses trans-Cinnamic acid is used in flavors, synthetic indigo and pharmaceuticals. It is involved in the production of methyl, ethyl and benzyl esters, which is used in the perfume industry. It serves as a precursor to the sweetener aspartame through enzyme-catalyzed amination to phenylalanine. It is a self-inhibitor produced by fungal spores to prevent germination. In addition, it is used to establish phenolic compounds by liquid chromatography, ultraviolet and mass spectrometry. It is utilized as a potential agent, thereby preventing lung tumor cells from metastasizing. Further, it induces intracellular release of calcium ions from the vacuole to the cytoplasm in order to trigger phytotoxicity in cucumber. Uses trans-Cinnamic acid was used to establish library of phenolic compounds by liquid chromatography/ultraviolet and mass spectrometry/mass spectrometry. General Description trans-Cinnamic acid is an α,β-unsaturated aromatic acid that can be used as a flavoring agent. It is mainly used to prepare ester derivatives that are used in perfume industry. trans-Cinnamic acid is the key volatile components of cinnamon essential oil. Biochem/physiol Actions trans-cinnamic acid has inhibitory effect on phorbol-12-myristate-13-acetate-induced invasion of human lung adenocarcinoma A549 cells. It is a potential agent which can prevent lung tumor cells from metastasizing. It induces intracellular release of Ca2+ from the vacuole to the cytoplasm which triggers phytotoxicity in cucumber. Purification Methods Crystallise the acid from *benzene, CCl4, hot water, water/EtOH (3:1), or 20% aqueous EtOH. Dry it at 60o in vacuo. It is steam volatile. [Beilstein 9 IV 2002.]   trans-Cinnamic acid Preparation Products And Raw materials Raw materials Acetic anhydride Preparation Products Cinnamyl alcohol-->Phenylacetaldehyde-->cyclamen aldehyde-->alpha-Amylcinnamaldehyde-->Docetaxel-->Cinnamic acid-->Ethyl cinnamate-->3-CHLOROBENZO[B]THIOPHENE-2-CARBOXAMIDE-->3-CHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID HYDRAZIDE-->METHYL 3-CHLOROBENZO[B]THIOPHENE-2-CARBOXYLATE-->Lacidipine-->Cinnamyl cinnamate-->3-CHLOROBENZO[B]THIOPHENE-2-CARBOXYLIC ACID-->3-CHLOROBENZO[B]THIOPHENE-2-CARBONYL CHLORIDE-->Benzyl cinnamate-->ALLYL CINNAMATE-->4-Hydroxy-3-methoxystyrene-->Dihydrocoumarin-->Methyl cinnamate