China Largest Manufacturer factory sales D(-)-Arginine CAS 157-06-2 CAS NO.157-06-2

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D(-)-Arginine Basic information Product Name: D(-)-Arginine Synonyms: (2R)-2-ammonio-5-(diaminomethylideneammonio)pentanoate;R-(-)-ARGININE;(R)-2-AMINO-5-GUANIDINOPENTANOIC ACID;RARECHEM AB PP 1748;D-ARG;D-(-)-ARGININE;D-ARGININE;D-2-AMINO-5-GUANIDINOVALERIC ACID CAS: 157-06-2 MF: C6H14N4O2 MW: 174.2 EINECS: 205-866-5 Product Categories: amino;Amino Acids;Arginine [Arg, R];Amino Acids and Derivatives;alpha-Amino Acids;Amino Acids;Amino Acids Derivatives;chiral;PROTECTED AMINO ACID & PEPTIDES;Biochemistry;for Resolution of Acids;Optical Resolution;Synthetic Organic Chemistry Mol File: 157-06-2.mol   D(-)-Arginine Chemical Properties Melting point  226 °C (dec.) (lit.) alpha  -28.5 º (c=8, 6 N HCl) Boiling point  305.18°C (rough estimate) density  1.2297 (rough estimate) refractive index  -23 ° (C=8, 6mol/L HCl) storage temp.  Keep in dark place,Inert atmosphere,Room temperature solubility  Aqueous Acid (Slightly), Water (Slightly) form  Solid pka 2.49±0.24(Predicted) color  White to Off-White Water Solubility  SOLUBLE Sensitive  Air Sensitive BRN  1725412 InChIKey ODKSFYDXXFIFQN-SCSAIBSYSA-N CAS DataBase Reference 157-06-2(CAS DataBase Reference) EPA Substance Registry System D-Arginine (157-06-2)   Safety Information Hazard Codes  Xi,Xn Risk Statements  36-36/37/38-20/21/22 Safety Statements  26-36 WGK Germany  3 RTECS  CF1934220 F  9 TSCA  Yes HazardClass  IRRITANT HS Code  29252000 MSDS Information Provider Language D(-)-Arginine English ACROS English SigmaAldrich English ALFA English   D(-)-Arginine Usage And Synthesis Description D-arginine is the D-form of arginine, which is a kind of amino acids. It can be reacted with hydrogen peroxide for non-enzymatic synthesis of nitric oxide. It has certain pharmacological activities. For example, its derivative, 1-deamino-8-D-arginine vasopressin is useful for the management of haemophilia and von Willebrand’s disease. It also has the potential to inhibit the proliferation of certain cancer cells. In biological research, D-arginine is frequently used in the studies of L-arginine/nitric oxide pathway as an inactive form of L-arginine. Chemical Properties white to light yellow crystal powde Uses Arginine is an essential amino acid found in food and plant sources, and many biological systems. D-Arginine is extensively used in studies on L-arginine/nitric oxide pathway as an inactive form of L-arginine, even in man. D-Arginine is slightly soluble (in water) and a moderately acidic compound (based on its pKa). D-Arginine can be found in human epidermis and platelet tissues. Within the cell, D-arginine is primarily located in the peroxisome. D-Arginine specifically can inhibit arginine decarboxylase enzymes and also functions as a metabolite. Uses 1-Deamino-8-D-arginine vasopressin makes a new pharmacological approach to the management of haemophilia and von Willebrand's disease. A novel nonenzymatic pathway for the generation of nitric oxide is by the reaction of hydrogen peroxide and d- or l-arginine. Definition ChEBI: A D-alpha-amino acid that is the D-isomer of arginine. References # Iannucci, N. B., et al. "Antiproliferative effect of 1-deamino-8-D-arginine vasopressin analogs on human breast cancer cells." Future Medicinal Chemistry 3.16(2011):1987-1993. Ripoll, Giselle, et al. "Angiostatic activity of 1-Deamino-8-D-Arginine vasopressin and novel peptide analogues in breast cancer cells." Cancer Research 68(2008). Navarro, Eduardo, et al. "Toxicological and Pharmacological Effects of D-Arginine." Basic & Clinical Pharmacology & Toxicology97.3(2005):149-154.   D(-)-Arginine Preparation Products And Raw materials Raw materials D-Ornithine monohydrochloride

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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D(-)-Arginine Basic information Product Name: D(-)-Arginine Synonyms: (2R)-2-ammonio-5-(diaminomethylideneammonio)pentanoate;R-(-)-ARGININE;(R)-2-AMINO-5-GUANIDINOPENTANOIC ACID;RARECHEM AB PP 1748;D-ARG;D-(-)-ARGININE;D-ARGININE;D-2-AMINO-5-GUANIDINOVALERIC ACID CAS: 157-06-2 MF: C6H14N4O2 MW: 174.2 EINECS: 205-866-5 Product Categories: amino;Amino Acids;Arginine [Arg, R];Amino Acids and Derivatives;alpha-Amino Acids;Amino Acids;Amino Acids Derivatives;chiral;PROTECTED AMINO ACID & PEPTIDES;Biochemistry;for Resolution of Acids;Optical Resolution;Synthetic Organic Chemistry Mol File: 157-06-2.mol   D(-)-Arginine Chemical Properties Melting point  226 °C (dec.) (lit.) alpha  -28.5 º (c=8, 6 N HCl) Boiling point  305.18°C (rough estimate) density  1.2297 (rough estimate) refractive index  -23 ° (C=8, 6mol/L HCl) storage temp.  Keep in dark place,Inert atmosphere,Room temperature solubility  Aqueous Acid (Slightly), Water (Slightly) form  Solid pka 2.49±0.24(Predicted) color  White to Off-White Water Solubility  SOLUBLE Sensitive  Air Sensitive BRN  1725412 InChIKey ODKSFYDXXFIFQN-SCSAIBSYSA-N CAS DataBase Reference 157-06-2(CAS DataBase Reference) EPA Substance Registry System D-Arginine (157-06-2)   Safety Information Hazard Codes  Xi,Xn Risk Statements  36-36/37/38-20/21/22 Safety Statements  26-36 WGK Germany  3 RTECS  CF1934220 F  9 TSCA  Yes HazardClass  IRRITANT HS Code  29252000 MSDS Information Provider Language D(-)-Arginine English ACROS English SigmaAldrich English ALFA English   D(-)-Arginine Usage And Synthesis Description D-arginine is the D-form of arginine, which is a kind of amino acids. It can be reacted with hydrogen peroxide for non-enzymatic synthesis of nitric oxide. It has certain pharmacological activities. For example, its derivative, 1-deamino-8-D-arginine vasopressin is useful for the management of haemophilia and von Willebrand’s disease. It also has the potential to inhibit the proliferation of certain cancer cells. In biological research, D-arginine is frequently used in the studies of L-arginine/nitric oxide pathway as an inactive form of L-arginine. Chemical Properties white to light yellow crystal powde Uses Arginine is an essential amino acid found in food and plant sources, and many biological systems. D-Arginine is extensively used in studies on L-arginine/nitric oxide pathway as an inactive form of L-arginine, even in man. D-Arginine is slightly soluble (in water) and a moderately acidic compound (based on its pKa). D-Arginine can be found in human epidermis and platelet tissues. Within the cell, D-arginine is primarily located in the peroxisome. D-Arginine specifically can inhibit arginine decarboxylase enzymes and also functions as a metabolite. Uses 1-Deamino-8-D-arginine vasopressin makes a new pharmacological approach to the management of haemophilia and von Willebrand's disease. A novel nonenzymatic pathway for the generation of nitric oxide is by the reaction of hydrogen peroxide and d- or l-arginine. Definition ChEBI: A D-alpha-amino acid that is the D-isomer of arginine. References # Iannucci, N. B., et al. "Antiproliferative effect of 1-deamino-8-D-arginine vasopressin analogs on human breast cancer cells." Future Medicinal Chemistry 3.16(2011):1987-1993. Ripoll, Giselle, et al. "Angiostatic activity of 1-Deamino-8-D-Arginine vasopressin and novel peptide analogues in breast cancer cells." Cancer Research 68(2008). Navarro, Eduardo, et al. "Toxicological and Pharmacological Effects of D-Arginine." Basic & Clinical Pharmacology & Toxicology97.3(2005):149-154.   D(-)-Arginine Preparation Products And Raw materials Raw materials D-Ornithine monohydrochloride