China Largest Manufacturer factory Supply Decanoic Acid CAS 334-48-5 CAS NO.334-48-5

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Decanoic acid Basic information Description References Product Name: Decanoic acid Synonyms: acidedecanoique;Caprinsαure;Caprynic acid;caprynicacid;Decansαure;Decatoicacid;Decoic acid;decoicacid CAS: 334-48-5 MF: C10H20O2 MW: 172.26 EINECS: 206-376-4 Product Categories: Vaccinium macrocarpon (Cranberry);Biochemicals and Reagents;Building Blocks;C10;Carbonyl Compounds;Carboxylic Acids;Pharmaceutical Intermediates;Alkylcarboxylic Acids;Monofunctional & alpha,omega-Bifunctional Alkanes;Monofunctional Alkanes;Chemical Synthesis;Elettaria Cardamomum (Cardamom);Fatty Acids and conjugates;Flavour Enhancer and Aromas;Fatty Acyls;Lipids;Nutrition Research;Organic Building Blocks;Phytochemicals by Plant (Food/Spice/Herb);Straight Chain Fatty Acids;Zingiber officinale (Ginger) Mol File: 334-48-5.mol   Decanoic acid Chemical Properties Melting point  27-32 °C(lit.) Boiling point  268-270 °C(lit.) density  0.893 g/mL at 25 °C(lit.) vapor pressure  15 mm Hg ( 160 °C) FEMA  2364 | DECANOIC ACID refractive index  1.4169 Fp  >230 °F storage temp.  room temp solubility  Chloroform (Slightly), Methanol (Slightly) pka 4.79±0.10(Predicted) form  Crystalline Solid color  White Odor Odorless PH 4 (0.2g/l, H2O, 20℃) Water Solubility  0.15 g/L (20 º C) Merck  14,1758 JECFA Number 105 BRN  1754556 Stability: Stable. Incompatible with bases, reducing agents, oxidizing agents. CAS DataBase Reference 334-48-5(CAS DataBase Reference) NIST Chemistry Reference Decanoic acid(334-48-5) EPA Substance Registry System Decanoic acid (334-48-5)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38-36/38 Safety Statements  26-36-37/39 WGK Germany  1 RTECS  HD9100000 Hazard Note  Irritant TSCA  Yes HS Code  29159080 Hazardous Substances Data 334-48-5(Hazardous Substances Data) Toxicity LD50 i.v. in mice: 129 ±5.4 mg/kg (Or, Wretlind) MSDS Information Provider Language Capric acid English SigmaAldrich English ACROS English ALFA English   Decanoic acid Usage And Synthesis Description Decanoic acid (capric acid) is a saturated fatty acid with a 10-carbon backbone. It occurs naturally in coconut oils, palm kernel oil, and the milk of cow/goat. Capric acid is most commonly used in the cosmetic and personal care, food/beverage, and pharmaceutical industries. It is also used as an intermediate in chemical syntheses. Furthermore, it is used in organic synthesis and in the manufacture of lubricants, greases, rubber, plastics, and dyes. References [1] # [2] # [3] # [4] #   Description Decanoic acid, or capric acid, is a saturated fatty acid. Its formula is CH3(CH2)8COOH. Salts and esters of decanoic acid are called decanoates or "caprates". The term capric acid arises from the Latin "capric" which pertains to goats due to their olfactory similarities. Capric acid occurs naturally in coconut oil (about 10%) and palm kernel oil (about 4 %), otherwise it is uncommon in typical seed oils. It is found in the milk of various mammals and to a lesser extent in other animal fats. Two other acids are named after goats: caproic (a C6 fatty acid) and caprylic (a C8 fatty acid). Along with decanoic acid, these total 15 % in goat milk fat. Chemical Properties White crystalline solid or needles. Unpleasant, rancid odor. Chemical Properties white crystals with an unpleasant odour Chemical Properties Fatty, unpleasant, rancid odor. Occurrence Reported found in apple, beer, preferments of bread, butter, oil, cheese, blue cheese, Romano cheese, cheddar cheese, Roquefort cheese, roasted cocoa bean, cognac, muscat grape, grape musts and wine, and other natural sources. Also reported in citrus peel oils, orange juice, apricots, guava, papaya, strawberry, butter, yogurt, milk, mutton, hop oil, Bourbon and Scotch whiskey, rum, coffee, mango and tea. Uses Manufacturing of esters for artificial fruit flavors and perfumes. Also as an intermediate in chemical syntheses. It is used in organic synthesis and industrially in the manufacture of perfumes, lubricants, greases, rubber, dyes, plastics, food additives and pharmaceuticals. Pharmaceuticals Decanoate salts and esters of various drugs are available. Since decanoic acid is a fatty acid, forming a salt or ester with a drug will increase its lipophilicity and its affinity for fatty tissue. Since distribution of a drug from fatty tissue is usually slow, one may develop a long-acting injectable form of a drug (called a Depot injection) by using its decanoate form. Some examples of drugs available as a decanoate ester or salt include nandrolone, fluphenazine, bromperidol, haloperidol and vanoxerine. Uses Decanoic acid is used in manufacturing of esters for artificial fruit flavors and perfumes. Uses manufacture of esters for artificial fruit flavors and perfumes; as an intermediate in other chemical syntheses. Uses Intermediates of Liquid Crystals Production Methods Decanoic acid can be prepared from oxidation of primary alcohol decanol, by using chromium trioxide (CrO3) oxidant under acidic conditions. Neutralization of decanoic acid or saponification of its esters, typically triglycerides, with sodium hydroxide will give sodium decanoate. This salt (CH3(CH2)8COO-Na+) is a component of some types of soap. Definition ChEBI: A C10, straight-chain saturated fatty acid. Preparation Prepared by oxidation of decanol. Aroma threshold values Detection: 2.2 to 102 ppm Synthesis Reference(s) Synthetic Communications, 20, p. 1617, 1990 DOI: 10.1080/00397919008053081 Synthesis, p. 99, 1970 General Description White crystalline solid with a rancid odor. Melting point 31.5°C. Soluble in most organic solvents and in dilute nitric acid; non-toxic. Used to make esters for perfumes and fruit flavors and as an intermediate for food-grade additives. Air & Water Reactions Insoluble in water. Reactivity Profile Capric acid reacts exothermically to neutralize bases. Can react with active metals to form gaseous hydrogen and a metal salt. May absorb enough water from the air and dissolve sufficiently in Capric acid to corrode or dissolve iron, steel, and aluminum parts and containers. Reacts with cyanide salts or solutions of cyanide salts to generate gaseous hydrogen cyanide. Reacts exothermically with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides to generate flammable and/or toxic gases. Can react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Reacts with carbonates and bicarbonates to generate a harmless gas (carbon dioxide). Can be oxidized exothermically by strong oxidizing agents and reduced by strong reducing agents; a wide variety of products is possible. May initiate polymerization reactions or catalyze (increase the rate of) reactions among other materials. Health Hazard Harmful if swallowed or inhaled. Material is irritating to tissues of mucous membranes, and upper respiratory tract, eyes and skin. Fire Hazard Capric acid is combustible. Biochem/physiol Actions Decanoic acid is helpful in the attenuation of oxidative stress. Decanoic acid in ketogenic diet is involved in mitochondrial biogenesis thereby enhancing the citrate synthase and complex I activity of electron transport chain. Safety Profile Poison by intravenous route. Mutation data reported. A moderate skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes. Potential Exposure Deconoic acid (fatty acids, saturated, linear, number of C-atoms ≥8 and ≤12, with termi- nating carboxyl group) is a carboxylic acid microbiocide used in cleaning, sanitizing and disinfecting applications for food processors and dairy farmers. Shipping UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required. Purification Methods The acid is best purified by conversion into its methyl ester, b 114.0o/15mm (using excess MeOH, in the presence of H2SO4). The H2SO4 and MeOH are removed, the ester is distilled in vacuo through a 3ft column packed with glass helices. The acid is then obtained from the ester by saponification and vacuum distillation. [Trachtman & Miller J Am Chem Soc 84 4828 1962, Beilstein 2 IV 1041.] Incompatibilities An organic carboxylic acid. Keep away from oxidizers, sulfuric acid, caustics, ammonia, aliphatic amines, alkanolamines, isocyanates, alkylene oxides, and epichlorohydrin. Corrosive solution; attacks most common metals. React violently with strong oxidizers, bromine, 90% hydrogen peroxide, phosphorus trichloride, silver powders or dust. Mixture with some silver compounds forms explosive salts of silver oxalate. Incompatible with silver compounds. Waste Disposal Recycle any unused portion of the material for its approved use or return it to the manu- facturer or supplier. Ultimate disposal of the chemical must consider: the material’s impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations .   Decanoic acid Preparation Products And Raw materials Raw materials Lauric acid-->Coconut oil-->Litsea cubeba oil-->LAUREL OIL FROM LAURUS NOBILIS-->COCONUT OIL FATTY ACIDS-->Tris(4-bromophenyl)amine-->2,4-Dimethoxybenzaldehyde Preparation Products TETRAKIS(DECYL)AMMONIUM BROMIDE-->Decyl aldehyde-->Misoprostol-->Decylamine-->2-Nitroacetophenone-->SEBACIC ACID DI-N-OCTYL ESTER-->2-Undecanone-->Diisooctyl sebacate-->MONOCAPRYLIN-->Ethyl caprate-->Emollient for chewing gums-->Decanoyl/octanoyl-glycerides-->5-Decanolide-->Decanoyl chloride-->1,2-DIDECANOYL-SN-GLYCEROL

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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Decanoic acid Basic information Description References Product Name: Decanoic acid Synonyms: acidedecanoique;Caprinsαure;Caprynic acid;caprynicacid;Decansαure;Decatoicacid;Decoic acid;decoicacid CAS: 334-48-5 MF: C10H20O2 MW: 172.26 EINECS: 206-376-4 Product Categories: Vaccinium macrocarpon (Cranberry);Biochemicals and Reagents;Building Blocks;C10;Carbonyl Compounds;Carboxylic Acids;Pharmaceutical Intermediates;Alkylcarboxylic Acids;Monofunctional & alpha,omega-Bifunctional Alkanes;Monofunctional Alkanes;Chemical Synthesis;Elettaria Cardamomum (Cardamom);Fatty Acids and conjugates;Flavour Enhancer and Aromas;Fatty Acyls;Lipids;Nutrition Research;Organic Building Blocks;Phytochemicals by Plant (Food/Spice/Herb);Straight Chain Fatty Acids;Zingiber officinale (Ginger) Mol File: 334-48-5.mol   Decanoic acid Chemical Properties Melting point  27-32 °C(lit.) Boiling point  268-270 °C(lit.) density  0.893 g/mL at 25 °C(lit.) vapor pressure  15 mm Hg ( 160 °C) FEMA  2364 | DECANOIC ACID refractive index  1.4169 Fp  >230 °F storage temp.  room temp solubility  Chloroform (Slightly), Methanol (Slightly) pka 4.79±0.10(Predicted) form  Crystalline Solid color  White Odor Odorless PH 4 (0.2g/l, H2O, 20℃) Water Solubility  0.15 g/L (20 º C) Merck  14,1758 JECFA Number 105 BRN  1754556 Stability: Stable. Incompatible with bases, reducing agents, oxidizing agents. CAS DataBase Reference 334-48-5(CAS DataBase Reference) NIST Chemistry Reference Decanoic acid(334-48-5) EPA Substance Registry System Decanoic acid (334-48-5)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38-36/38 Safety Statements  26-36-37/39 WGK Germany  1 RTECS  HD9100000 Hazard Note  Irritant TSCA  Yes HS Code  29159080 Hazardous Substances Data 334-48-5(Hazardous Substances Data) Toxicity LD50 i.v. in mice: 129 ±5.4 mg/kg (Or, Wretlind) MSDS Information Provider Language Capric acid English SigmaAldrich English ACROS English ALFA English   Decanoic acid Usage And Synthesis Description Decanoic acid (capric acid) is a saturated fatty acid with a 10-carbon backbone. It occurs naturally in coconut oils, palm kernel oil, and the milk of cow/goat. Capric acid is most commonly used in the cosmetic and personal care, food/beverage, and pharmaceutical industries. It is also used as an intermediate in chemical syntheses. Furthermore, it is used in organic synthesis and in the manufacture of lubricants, greases, rubber, plastics, and dyes. References [1] # [2] # [3] # [4] #   Description Decanoic acid, or capric acid, is a saturated fatty acid. Its formula is CH3(CH2)8COOH. Salts and esters of decanoic acid are called decanoates or "caprates". The term capric acid arises from the Latin "capric" which pertains to goats due to their olfactory similarities. Capric acid occurs naturally in coconut oil (about 10%) and palm kernel oil (about 4 %), otherwise it is uncommon in typical seed oils. It is found in the milk of various mammals and to a lesser extent in other animal fats. Two other acids are named after goats: caproic (a C6 fatty acid) and caprylic (a C8 fatty acid). Along with decanoic acid, these total 15 % in goat milk fat. Chemical Properties White crystalline solid or needles. Unpleasant, rancid odor. Chemical Properties white crystals with an unpleasant odour Chemical Properties Fatty, unpleasant, rancid odor. Occurrence Reported found in apple, beer, preferments of bread, butter, oil, cheese, blue cheese, Romano cheese, cheddar cheese, Roquefort cheese, roasted cocoa bean, cognac, muscat grape, grape musts and wine, and other natural sources. Also reported in citrus peel oils, orange juice, apricots, guava, papaya, strawberry, butter, yogurt, milk, mutton, hop oil, Bourbon and Scotch whiskey, rum, coffee, mango and tea. Uses Manufacturing of esters for artificial fruit flavors and perfumes. Also as an intermediate in chemical syntheses. It is used in organic synthesis and industrially in the manufacture of perfumes, lubricants, greases, rubber, dyes, plastics, food additives and pharmaceuticals. Pharmaceuticals Decanoate salts and esters of various drugs are available. Since decanoic acid is a fatty acid, forming a salt or ester with a drug will increase its lipophilicity and its affinity for fatty tissue. Since distribution of a drug from fatty tissue is usually slow, one may develop a long-acting injectable form of a drug (called a Depot injection) by using its decanoate form. Some examples of drugs available as a decanoate ester or salt include nandrolone, fluphenazine, bromperidol, haloperidol and vanoxerine. Uses Decanoic acid is used in manufacturing of esters for artificial fruit flavors and perfumes. Uses manufacture of esters for artificial fruit flavors and perfumes; as an intermediate in other chemical syntheses. Uses Intermediates of Liquid Crystals Production Methods Decanoic acid can be prepared from oxidation of primary alcohol decanol, by using chromium trioxide (CrO3) oxidant under acidic conditions. Neutralization of decanoic acid or saponification of its esters, typically triglycerides, with sodium hydroxide will give sodium decanoate. This salt (CH3(CH2)8COO-Na+) is a component of some types of soap. Definition ChEBI: A C10, straight-chain saturated fatty acid. Preparation Prepared by oxidation of decanol. Aroma threshold values Detection: 2.2 to 102 ppm Synthesis Reference(s) Synthetic Communications, 20, p. 1617, 1990 DOI: 10.1080/00397919008053081 Synthesis, p. 99, 1970 General Description White crystalline solid with a rancid odor. Melting point 31.5°C. Soluble in most organic solvents and in dilute nitric acid; non-toxic. Used to make esters for perfumes and fruit flavors and as an intermediate for food-grade additives. Air & Water Reactions Insoluble in water. Reactivity Profile Capric acid reacts exothermically to neutralize bases. Can react with active metals to form gaseous hydrogen and a metal salt. May absorb enough water from the air and dissolve sufficiently in Capric acid to corrode or dissolve iron, steel, and aluminum parts and containers. Reacts with cyanide salts or solutions of cyanide salts to generate gaseous hydrogen cyanide. Reacts exothermically with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides to generate flammable and/or toxic gases. Can react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Reacts with carbonates and bicarbonates to generate a harmless gas (carbon dioxide). Can be oxidized exothermically by strong oxidizing agents and reduced by strong reducing agents; a wide variety of products is possible. May initiate polymerization reactions or catalyze (increase the rate of) reactions among other materials. Health Hazard Harmful if swallowed or inhaled. Material is irritating to tissues of mucous membranes, and upper respiratory tract, eyes and skin. Fire Hazard Capric acid is combustible. Biochem/physiol Actions Decanoic acid is helpful in the attenuation of oxidative stress. Decanoic acid in ketogenic diet is involved in mitochondrial biogenesis thereby enhancing the citrate synthase and complex I activity of electron transport chain. Safety Profile Poison by intravenous route. Mutation data reported. A moderate skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes. Potential Exposure Deconoic acid (fatty acids, saturated, linear, number of C-atoms ≥8 and ≤12, with termi- nating carboxyl group) is a carboxylic acid microbiocide used in cleaning, sanitizing and disinfecting applications for food processors and dairy farmers. Shipping UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required. Purification Methods The acid is best purified by conversion into its methyl ester, b 114.0o/15mm (using excess MeOH, in the presence of H2SO4). The H2SO4 and MeOH are removed, the ester is distilled in vacuo through a 3ft column packed with glass helices. The acid is then obtained from the ester by saponification and vacuum distillation. [Trachtman & Miller J Am Chem Soc 84 4828 1962, Beilstein 2 IV 1041.] Incompatibilities An organic carboxylic acid. Keep away from oxidizers, sulfuric acid, caustics, ammonia, aliphatic amines, alkanolamines, isocyanates, alkylene oxides, and epichlorohydrin. Corrosive solution; attacks most common metals. React violently with strong oxidizers, bromine, 90% hydrogen peroxide, phosphorus trichloride, silver powders or dust. Mixture with some silver compounds forms explosive salts of silver oxalate. Incompatible with silver compounds. Waste Disposal Recycle any unused portion of the material for its approved use or return it to the manu- facturer or supplier. Ultimate disposal of the chemical must consider: the material’s impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations .   Decanoic acid Preparation Products And Raw materials Raw materials Lauric acid-->Coconut oil-->Litsea cubeba oil-->LAUREL OIL FROM LAURUS NOBILIS-->COCONUT OIL FATTY ACIDS-->Tris(4-bromophenyl)amine-->2,4-Dimethoxybenzaldehyde Preparation Products TETRAKIS(DECYL)AMMONIUM BROMIDE-->Decyl aldehyde-->Misoprostol-->Decylamine-->2-Nitroacetophenone-->SEBACIC ACID DI-N-OCTYL ESTER-->2-Undecanone-->Diisooctyl sebacate-->MONOCAPRYLIN-->Ethyl caprate-->Emollient for chewing gums-->Decanoyl/octanoyl-glycerides-->5-Decanolide-->Decanoyl chloride-->1,2-DIDECANOYL-SN-GLYCEROL