ISO.HACCP.GMP.FDA.SGS.BV-China Largest Manufacturer factory Supply 2,4,5-Triamino-6-hydroxypyrimidine sulfate CAS 35011-47-3 CAS NO.35011-47-3

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Product Name: 2,4,5-Triamino-6-hydroxypyrimidine sulfate Synonyms: 6-HYDROXY-2,4,5-TRIAMINOPYRIMIDINE SULFATE HYDRATE;2,5,6-TRIAMINO-4-PYRIMIDINOL SULFATE HYDRATE;2,5,6-TRIAMINO-4(1H)-PYRIMIDINONE SULFATE HYDRATE;4-HYDROXY-2,5,6-TRIAMINOPYRIMIDINE;2,5,6-Triamino-4(1H)-pyrimidinone sulfate;4-hydroxy-2,5,6-triaminopyrimidine sulf. monohydr. (6-2,4,5);2,5,6-triamino-4-pyrimidol sulfate salt;4-hydroxy-2,5,6-triaminopyrimidine sulfate salt CAS: 35011-47-3 MF: C4H9N5O5S MW: 239.21 EINECS: 609-054-5 Product Categories: Heterocyclic Compounds Mol File: 35011-47-3.mol   2,4,5-Triamino-6-hydroxypyrimidine sulfate Chemical Properties Melting point  ≥300 °C(lit.) RTECS  UW7175000 storage temp.  Inert atmosphere,Room Temperature solubility  Soluble in DMSO. form  Solid color  Pale Yellow CAS DataBase Reference 35011-47-3(CAS DataBase Reference)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  26-36 WGK Germany  3 HS Code  29349990 MSDS Information Provider Language ACROS English   2,4,5-Triamino-6-hydroxypyrimidine sulfate Usage And Synthesis 用途 6-Hydroxy-2,4,5-triaminopyrimidine, Sulfate (cas# 35011-47-3) is a compound useful in organic synthesis. Chemical Properties yellow-beige crystalline powder Uses 2,4,5-Triamino-6-hydroxypyrimidine sulfate is used in the preparation of guanines and other purine derivatives with antiviral activities. Uses 2,4,5-Triamino-6-hydroxypyrimidine Sulfate Salt is an intermediate used in the preparation of labelled 2-Amino-6,8-dihydroxypurine Hydrochloride (A604920). A labelled substituted 5-aminopyrimidines with antioxidative activity. Purification Methods This salt has very low solubility in H2O. It is best purified by conversion into the dihydrochloride salt, which is then re-converted to the insoluble sulfate salt. The sulfate salt (2.57g, 10mmoles) is suspended in H2O (20mL) containing BaCl2 (10mmoles) and stirred in a boiling water bath for 15minutes. After cooling, the insoluble BaSO4 is filtered off and washed with boiling H2O (10mL). The combined filtrate and washings are made acidic with HCl and evaporated to dryness. The residual hydrochloride salt is recrystallised from H2O by adding conc HCl whereby the dihydrochloride salt separates as clusters which darken at 260o and dec > 300o[darkening > 360o]. [Baugh & Shaw J Org Chem 29 3610 1964, King & Spengley J Chem Soc 2144 1952]. The hydrochloride is then dissolved in H2O, and while hot an equivalent of H2SO4 is added when the sulfate separates as a white microcrystalline solid which is filtered off washed liberally with H2O and dried in vacuum over P2O5. [Albert & Wood J Appl Chem London 3 521 1953, UV: Cavalieri et al. J Am Chem Soc 70 3875 1948; see also Pfleiderer Chem Ber 90 2272 1957, Traube Chem Ber 33 1371 1900.] The hydrochloride has m > 300o. [Beilstein 25 II 384, 25 III/IV 3648.]   2,4,5-Triamino-6-hydroxypyrimidine sulfate Preparation Products And Raw materials

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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Product Name: 2,4,5-Triamino-6-hydroxypyrimidine sulfate Synonyms: 6-HYDROXY-2,4,5-TRIAMINOPYRIMIDINE SULFATE HYDRATE;2,5,6-TRIAMINO-4-PYRIMIDINOL SULFATE HYDRATE;2,5,6-TRIAMINO-4(1H)-PYRIMIDINONE SULFATE HYDRATE;4-HYDROXY-2,5,6-TRIAMINOPYRIMIDINE;2,5,6-Triamino-4(1H)-pyrimidinone sulfate;4-hydroxy-2,5,6-triaminopyrimidine sulf. monohydr. (6-2,4,5);2,5,6-triamino-4-pyrimidol sulfate salt;4-hydroxy-2,5,6-triaminopyrimidine sulfate salt CAS: 35011-47-3 MF: C4H9N5O5S MW: 239.21 EINECS: 609-054-5 Product Categories: Heterocyclic Compounds Mol File: 35011-47-3.mol   2,4,5-Triamino-6-hydroxypyrimidine sulfate Chemical Properties Melting point  ≥300 °C(lit.) RTECS  UW7175000 storage temp.  Inert atmosphere,Room Temperature solubility  Soluble in DMSO. form  Solid color  Pale Yellow CAS DataBase Reference 35011-47-3(CAS DataBase Reference)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  26-36 WGK Germany  3 HS Code  29349990 MSDS Information Provider Language ACROS English   2,4,5-Triamino-6-hydroxypyrimidine sulfate Usage And Synthesis 用途 6-Hydroxy-2,4,5-triaminopyrimidine, Sulfate (cas# 35011-47-3) is a compound useful in organic synthesis. Chemical Properties yellow-beige crystalline powder Uses 2,4,5-Triamino-6-hydroxypyrimidine sulfate is used in the preparation of guanines and other purine derivatives with antiviral activities. Uses 2,4,5-Triamino-6-hydroxypyrimidine Sulfate Salt is an intermediate used in the preparation of labelled 2-Amino-6,8-dihydroxypurine Hydrochloride (A604920). A labelled substituted 5-aminopyrimidines with antioxidative activity. Purification Methods This salt has very low solubility in H2O. It is best purified by conversion into the dihydrochloride salt, which is then re-converted to the insoluble sulfate salt. The sulfate salt (2.57g, 10mmoles) is suspended in H2O (20mL) containing BaCl2 (10mmoles) and stirred in a boiling water bath for 15minutes. After cooling, the insoluble BaSO4 is filtered off and washed with boiling H2O (10mL). The combined filtrate and washings are made acidic with HCl and evaporated to dryness. The residual hydrochloride salt is recrystallised from H2O by adding conc HCl whereby the dihydrochloride salt separates as clusters which darken at 260o and dec > 300o[darkening > 360o]. [Baugh & Shaw J Org Chem 29 3610 1964, King & Spengley J Chem Soc 2144 1952]. The hydrochloride is then dissolved in H2O, and while hot an equivalent of H2SO4 is added when the sulfate separates as a white microcrystalline solid which is filtered off washed liberally with H2O and dried in vacuum over P2O5. [Albert & Wood J Appl Chem London 3 521 1953, UV: Cavalieri et al. J Am Chem Soc 70 3875 1948; see also Pfleiderer Chem Ber 90 2272 1957, Traube Chem Ber 33 1371 1900.] The hydrochloride has m > 300o. [Beilstein 25 II 384, 25 III/IV 3648.]   2,4,5-Triamino-6-hydroxypyrimidine sulfate Preparation Products And Raw materials