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Home > Products >  China Biggest Factory manufacturer supply Pyridoxal 5'-phosphate monohydrate

China Biggest Factory manufacturer supply Pyridoxal 5'-phosphate monohydrate CAS NO.41468-25-1

  • FOB Price: USD: 1.00-2.00 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,Other
  • Available Specifications:

    AAAAA(50-100)KilogramAAAAA(100-500)Kilogram

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Keywords

  • Pyridoxal 5'-phosphate monohydrate
  • Pyridoxal 5'-phosphate monohydrate
  • 41468-25-1

Quick Details

  • ProName: China Biggest Factory manufacturer sup...
  • CasNo: 41468-25-1
  • Molecular Formula: 41468-25-1
  • Appearance: white powder
  • Application: Pharm chemicals industry
  • DeliveryTime: 3-5 days
  • PackAge: 25KG/Drum
  • Port: Shanghai Guangzhou Qingdao Shenzhen
  • ProductionCapacity: 200 Metric Ton/Month
  • Purity: 99%
  • Storage: 2-8°C
  • Transportation: By air /Sea/ coruier
  • LimitNum: 1 Kilogram
  • Heavy metal: 10PPM
  • Color: white
  • Melting point: ≥350°C
  • Boiling point: 363.24°C (rough estimate)
  • density: 1.667
  • solubility: 1 M NaOH: 10 mg/mL, dark green
  • Water Solubility: <0.1 g/100 mL at 21 oC
  • Stability: Stable. Combustible. Incompatible with...

Superiority

                                PRODUCT DETAILS                           

Pyridoxal 5'-phosphate monohydrate Basic information
Product Name: Pyridoxal 5'-phosphate monohydrate
Synonyms: 3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehydemonohydr;3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehydmonoh;3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde5-phosphatemonohydrat;phosphopyridoxalmonohydrate;pyridoxal,5-(dihydrogenphosphate),monohydrate;5-Phosphate Monohydrate;PYRIDOXAL-5-PHOSPHATEextrapure;Codecarboxylase, PLP, Pyridoxal 5-phosphate, 3-Hydroxy-2-methyl-5-([phosphonooxy]methyl)-4-pyridinecarboxaldehyde
CAS: 41468-25-1
MF: C8H12NO7P
MW: 265.16
EINECS: 609-929-1
Product Categories: Aldehydes;Analytical Reagents;Analytical/Chromatography;Building Blocks;C8;Carbonyl Compounds;Chemical Synthesis;Derivatization Reagents;Derivatization Reagents HPLC;Fluorescence;Nutrition Research;Organic Building Blocks;Vitamin B;Vitamin B6;Biochemistry;Vitamin Derivatives;Vitamins
Mol File: 41468-25-1.mol
Pyridoxal 5'-phosphate monohydrate Structure
 
Pyridoxal 5'-phosphate monohydrate Chemical Properties
Melting point  140-143 °C(lit.)
storage temp.  2-8°C
solubility  Acetonitrile (Slightly), DMSO (Slightly)
form  Crystalline Powder
color  Pale yellow
Water Solubility  5 g/L (20 ºC)
Sensitive  Light Sensitive
Merck  14,7979
BRN  234749
Stability: Air Sensitive, Moisture Sensitive
InChIKey CEEQUQSGVRRXQI-UHFFFAOYSA-N
CAS DataBase Reference 41468-25-1(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-36-26
WGK Germany  2
RTECS  UV1208000
8-10-23
TSCA  Yes
HS Code  29333990
MSDS Information
Provider Language
3-Hydroxy-2-methyl-5-([phosphonooxy]methyl)-4-pyridinecarboxaldehyde English
ACROS English
SigmaAldrich English
ALFA English
 
Pyridoxal 5'-phosphate monohydrate Usage And Synthesis
Chemical Properties Pyridoxal Phosphate Hydrate occurs as a pale yellow-white to light yellow crystalline powder.
It is slightly soluble in water, and practically insoluble in ethanol (99.5).
It dissolves in dilute hydrochloric acid and in sodium hydroxide TS.
The pH of a solution prepared by dissolving 0.1 g of Pyridoxal Phosphate Hydrate in 200 mL of water is between 3.0 and 3.5.
Pyridoxal Phosphate Hydrate is colored to light red by light.
Uses Pyridoxal 5-phosphate (PLP) (active form of Vitamin B6) is an enzyme prosthetic group that acts as a coenzyme in transamination, decarboxylation and deamination reactions such as the conversion of dopa into dopamine; of glutamate into GABA; of histidine to histamine. PLP works mechanistically through formation of a Schiff-base.
Uses Active form of Vitamin B-6Pyridoxal-5 -phosphate monohydrate is used to modify the lysyl and valyl residues in proteins. It acts as a coenzyme in transamination reactions and as an inhibitor for purinergic receptors and intracellular. It is involved in decarboxylation and deamination reactions viz. the conversion of dopa into dopamine of glutamate into GABA and histidine to histamine.
Application Pyridoxal 5′-phosphate (PLP), an active form of vitamin B6/ pyridoxine is the coenzyme of amino acid metabolism.
Pyridoxal 5′-phosphate monohydrate has been used:
as a component in the reaction mixture for ornithine decarboxylase (ODC) activity assay
as a standard to quantify the concentration of pyridoxal 5′-phosphate (PLP) in cerebrospinal fluid (CSF) of children
as a dietary supplement to study its effects on the lethal phenotype of mutant flies.
General Description

Pyridoxal 5′-phosphate (PLP), an active form of vitamin B6/ pyridoxine is the coenzyme of amino acid metabolism.

Biological Activity Pyridoxine participates in the production of lipid and neurotransmitters. Pyridoxal 5′-phosphate (PLP) serves as a cofactor to stabilize carbanions at Cα of amino acids. Pyridoxine deficiency results in peripheral neuropathy. Absence of PLP leads to neonatal epileptic encephalopathy. PLP acts as a coenzyme in transamination, decarboxylation and deamination reactions such as the conversion of dopa into dopamine; of glutamate into γ aminobutyric acid (GABA); of histidine to histamine. PLP works mechanistically through formation of a Schiff-base.
Biochem/physiol Actions Pyridoxine participates in the production of lipid and neurotransmitters. Pyridoxal 5′-phosphate (PLP) serves as a cofactor to stabilize carbanions at Cα of amino acids. Pyridoxine deficiency results in peripheral neuropathy. Absence of PLP leads to neonatal epileptic encephalopathy. PLP acts as a coenzyme in transamination, decarboxylation and deamination reactions such as the conversion of dopa into dopamine; of glutamate into γ aminobutyric acid (GABA); of histidine to histamine. PLP works mechanistically through formation of a Schiff-base.
 
Pyridoxal 5'-phosphate monohydrate Preparation Products And Raw materials
Preparation Products DL-Tryptophan


                                Group profiles

Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

 

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                                                       Product information

Pyridoxal 5'-phosphate monohydrate Basic information
Product Name: Pyridoxal 5'-phosphate monohydrate
Synonyms: 3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehydemonohydr;3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehydmonoh;3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde5-phosphatemonohydrat;phosphopyridoxalmonohydrate;pyridoxal,5-(dihydrogenphosphate),monohydrate;5-Phosphate Monohydrate;PYRIDOXAL-5-PHOSPHATEextrapure;Codecarboxylase, PLP, Pyridoxal 5-phosphate, 3-Hydroxy-2-methyl-5-([phosphonooxy]methyl)-4-pyridinecarboxaldehyde
CAS: 41468-25-1
MF: C8H12NO7P
MW: 265.16
EINECS: 609-929-1
Product Categories: Aldehydes;Analytical Reagents;Analytical/Chromatography;Building Blocks;C8;Carbonyl Compounds;Chemical Synthesis;Derivatization Reagents;Derivatization Reagents HPLC;Fluorescence;Nutrition Research;Organic Building Blocks;Vitamin B;Vitamin B6;Biochemistry;Vitamin Derivatives;Vitamins
Mol File: 41468-25-1.mol
Pyridoxal 5'-phosphate monohydrate Structure
 
Pyridoxal 5'-phosphate monohydrate Chemical Properties
Melting point  140-143 °C(lit.)
storage temp.  2-8°C
solubility  Acetonitrile (Slightly), DMSO (Slightly)
form  Crystalline Powder
color  Pale yellow
Water Solubility  5 g/L (20 ºC)
Sensitive  Light Sensitive
Merck  14,7979
BRN  234749
Stability: Air Sensitive, Moisture Sensitive
InChIKey CEEQUQSGVRRXQI-UHFFFAOYSA-N
CAS DataBase Reference 41468-25-1(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-36-26
WGK Germany  2
RTECS  UV1208000
8-10-23
TSCA  Yes
HS Code  29333990
MSDS Information
Provider Language
3-Hydroxy-2-methyl-5-([phosphonooxy]methyl)-4-pyridinecarboxaldehyde English
ACROS English
SigmaAldrich English
ALFA English
 
Pyridoxal 5'-phosphate monohydrate Usage And Synthesis
Chemical Properties Pyridoxal Phosphate Hydrate occurs as a pale yellow-white to light yellow crystalline powder.
It is slightly soluble in water, and practically insoluble in ethanol (99.5).
It dissolves in dilute hydrochloric acid and in sodium hydroxide TS.
The pH of a solution prepared by dissolving 0.1 g of Pyridoxal Phosphate Hydrate in 200 mL of water is between 3.0 and 3.5.
Pyridoxal Phosphate Hydrate is colored to light red by light.
Uses Pyridoxal 5-phosphate (PLP) (active form of Vitamin B6) is an enzyme prosthetic group that acts as a coenzyme in transamination, decarboxylation and deamination reactions such as the conversion of dopa into dopamine; of glutamate into GABA; of histidine to histamine. PLP works mechanistically through formation of a Schiff-base.
Uses Active form of Vitamin B-6Pyridoxal-5 -phosphate monohydrate is used to modify the lysyl and valyl residues in proteins. It acts as a coenzyme in transamination reactions and as an inhibitor for purinergic receptors and intracellular. It is involved in decarboxylation and deamination reactions viz. the conversion of dopa into dopamine of glutamate into GABA and histidine to histamine.
Application Pyridoxal 5′-phosphate (PLP), an active form of vitamin B6/ pyridoxine is the coenzyme of amino acid metabolism.
Pyridoxal 5′-phosphate monohydrate has been used:
as a component in the reaction mixture for ornithine decarboxylase (ODC) activity assay
as a standard to quantify the concentration of pyridoxal 5′-phosphate (PLP) in cerebrospinal fluid (CSF) of children
as a dietary supplement to study its effects on the lethal phenotype of mutant flies.
General Description

Pyridoxal 5′-phosphate (PLP), an active form of vitamin B6/ pyridoxine is the coenzyme of amino acid metabolism.

Biological Activity Pyridoxine participates in the production of lipid and neurotransmitters. Pyridoxal 5′-phosphate (PLP) serves as a cofactor to stabilize carbanions at Cα of amino acids. Pyridoxine deficiency results in peripheral neuropathy. Absence of PLP leads to neonatal epileptic encephalopathy. PLP acts as a coenzyme in transamination, decarboxylation and deamination reactions such as the conversion of dopa into dopamine; of glutamate into γ aminobutyric acid (GABA); of histidine to histamine. PLP works mechanistically through formation of a Schiff-base.
Biochem/physiol Actions Pyridoxine participates in the production of lipid and neurotransmitters. Pyridoxal 5′-phosphate (PLP) serves as a cofactor to stabilize carbanions at Cα of amino acids. Pyridoxine deficiency results in peripheral neuropathy. Absence of PLP leads to neonatal epileptic encephalopathy. PLP acts as a coenzyme in transamination, decarboxylation and deamination reactions such as the conversion of dopa into dopamine; of glutamate into γ aminobutyric acid (GABA); of histidine to histamine. PLP works mechanistically through formation of a Schiff-base.
 
Pyridoxal 5'-phosphate monohydrate Preparation Products And Raw materials
Preparation Products DL-Tryptophan

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