China Largest Manufacturer factory sales 6-Azauracil CAS 461-89-2 CAS NO.461-89-2

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6-Azauracil Basic information Product Name: 6-Azauracil Synonyms: 4(6)-Azauracil;As-Triazine-3,5(2H,4H)-dione;As-Triazine-3,5-diol;Azauracil;AZU;IPO 3834;ipo3834;NSC 3425 CAS: 461-89-2 MF: C3H3N3O2 MW: 113.07 EINECS: 207-318-0 Product Categories: Biochemistry;Nucleobases and their analogs;Pyridines, Pyrimidines, Purines and Pteredines;Nucleosides, Nucleotides & Related Reagents;Nucleic acids Mol File: 461-89-2.mol   6-Azauracil Chemical Properties Melting point  274-275 °C(lit.) Boiling point  211.75°C (rough estimate) density  1.5988 (rough estimate) refractive index  1.4264 (estimate) storage temp.  Store below +30°C. form  Fine Crystalline Powder pka 7.78±0.20(Predicted) color  White to light yellow Water Solubility  Partly soluble in water, ethanol, DMSO, and 1 M NH4OH (50 mg/ml). BRN  116472 CAS DataBase Reference 461-89-2(CAS DataBase Reference) NIST Chemistry Reference 1,2,4-Triazine-3,5(2H,4H)-dione(461-89-2) EPA Substance Registry System 1,2,4-Triazine-3,5(2H,4H)-dione (461-89-2)   Safety Information Hazard Codes  Xi,T Risk Statements  36/37/38-63-25 Safety Statements  26-36-45-38-36/37/39 WGK Germany  3 RTECS  XY7700000 F  10-23 TSCA  Yes HazardClass  IRRITANT HS Code  29336980 MSDS Information Provider Language 1,2,4-Triazine-3,5-dione English SigmaAldrich English ACROS English ALFA English   6-Azauracil Usage And Synthesis Chemical Properties white to light yellow fine crystalline powder Uses 6-Azauracil (6-AU) is used as a growth inhibitor of various microorganisms via depletion of intracellular GTP and UTP nucleotide pools. 6-Azauracil has been widely used in investigations on modulation of transcription, especially in yeast models. Definition ChEBI: A 1,2,4-triazine compound having oxo-substituents at the 3- and 5-positions. Synthesis Reference(s) The Journal of Organic Chemistry, 23, p. 1522, 1958 DOI: 10.1021/jo01104a033 Biochem/physiol Actions 6-Azauracil (6-AU) is a pyrimidine analog of uracil and exhibits antitumor activity. It inhibits the growth of various microorganisms by depleting intracellular guanosine triphosphate (GTP) and uridine triphosphate (UTP) nucleotide pools. Safety Profile Poison by intraperitoneal route. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.   6-Azauracil Preparation Products And Raw materials Raw materials [(aminocarbonyl)hydrazono]acetic acid-->3,5-Dihydroxy-[1,2,4]triazine-6-carboxylic acid-->6-AZA-2-THIOURACIL-->6-AZAURACIL-->Benzonitrile Preparation Products PARABANIC ACID-->5-Bromo-6-azauracil

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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6-Azauracil Basic information Product Name: 6-Azauracil Synonyms: 4(6)-Azauracil;As-Triazine-3,5(2H,4H)-dione;As-Triazine-3,5-diol;Azauracil;AZU;IPO 3834;ipo3834;NSC 3425 CAS: 461-89-2 MF: C3H3N3O2 MW: 113.07 EINECS: 207-318-0 Product Categories: Biochemistry;Nucleobases and their analogs;Pyridines, Pyrimidines, Purines and Pteredines;Nucleosides, Nucleotides & Related Reagents;Nucleic acids Mol File: 461-89-2.mol   6-Azauracil Chemical Properties Melting point  274-275 °C(lit.) Boiling point  211.75°C (rough estimate) density  1.5988 (rough estimate) refractive index  1.4264 (estimate) storage temp.  Store below +30°C. form  Fine Crystalline Powder pka 7.78±0.20(Predicted) color  White to light yellow Water Solubility  Partly soluble in water, ethanol, DMSO, and 1 M NH4OH (50 mg/ml). BRN  116472 CAS DataBase Reference 461-89-2(CAS DataBase Reference) NIST Chemistry Reference 1,2,4-Triazine-3,5(2H,4H)-dione(461-89-2) EPA Substance Registry System 1,2,4-Triazine-3,5(2H,4H)-dione (461-89-2)   Safety Information Hazard Codes  Xi,T Risk Statements  36/37/38-63-25 Safety Statements  26-36-45-38-36/37/39 WGK Germany  3 RTECS  XY7700000 F  10-23 TSCA  Yes HazardClass  IRRITANT HS Code  29336980 MSDS Information Provider Language 1,2,4-Triazine-3,5-dione English SigmaAldrich English ACROS English ALFA English   6-Azauracil Usage And Synthesis Chemical Properties white to light yellow fine crystalline powder Uses 6-Azauracil (6-AU) is used as a growth inhibitor of various microorganisms via depletion of intracellular GTP and UTP nucleotide pools. 6-Azauracil has been widely used in investigations on modulation of transcription, especially in yeast models. Definition ChEBI: A 1,2,4-triazine compound having oxo-substituents at the 3- and 5-positions. Synthesis Reference(s) The Journal of Organic Chemistry, 23, p. 1522, 1958 DOI: 10.1021/jo01104a033 Biochem/physiol Actions 6-Azauracil (6-AU) is a pyrimidine analog of uracil and exhibits antitumor activity. It inhibits the growth of various microorganisms by depleting intracellular guanosine triphosphate (GTP) and uridine triphosphate (UTP) nucleotide pools. Safety Profile Poison by intraperitoneal route. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.   6-Azauracil Preparation Products And Raw materials Raw materials [(aminocarbonyl)hydrazono]acetic acid-->3,5-Dihydroxy-[1,2,4]triazine-6-carboxylic acid-->6-AZA-2-THIOURACIL-->6-AZAURACIL-->Benzonitrile Preparation Products PARABANIC ACID-->5-Bromo-6-azauracil