PRODUCT DETAILS
| 5-Bromouracil Basic information |
| Product Name: |
5-Bromouracil |
| Synonyms: |
BROMOURACIL;BROMOURACIL, 5-;BUTTPARK 48\06-06;5-BROMO-2,4-DIHYDROXYPYRIMIDINE;5-BROMO-2,3-DIHYDROXYPYRIMIDINE;5-BROMO-2,4-(1H,3H)-PYRIMIDINEDIONE;5-BROMO-1H-PYRIMIDINE-2,4-DIONE;2,4(1H,3H)-Pyrimidinedione, 5-bromo- |
| CAS: |
51-20-7 |
| MF: |
C4H3BrN2O2 |
| MW: |
190.98 |
| EINECS: |
200-084-0 |
| Product Categories: |
Detergents;Biochemistry;Nucleobases and their analogs;Nucleosides, Nucleotides & Related Reagents;Nucleic acids;Bases & Related Reagents;Pyrimidine series;Mutagenesis Research Chemicals;Nucleotides |
| Mol File: |
51-20-7.mol |
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| 5-Bromouracil Chemical Properties |
| Melting point |
>300 °C (lit.) |
| density |
1.8710 (rough estimate) |
| refractive index |
1.6200 (estimate) |
| storage temp. |
Keep in dark place,Sealed in dry,Room Temperature |
| solubility |
<1g/l |
| form |
Solid |
| pka |
6.77±0.10(Predicted) |
| color |
White |
| Water Solubility |
SOLUBLE IN COLD WATER |
| Merck |
14,1445 |
| BRN |
127176 |
| InChIKey |
LQLQRFGHAALLLE-UHFFFAOYSA-N |
| CAS DataBase Reference |
51-20-7(CAS DataBase Reference) |
| NIST Chemistry Reference |
5-Bromouracil(51-20-7) |
| EPA Substance Registry System |
5-Bromouracil (51-20-7) |
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| 5-Bromouracil Usage And Synthesis |
| Chemical Properties |
Prisms from H 2 O. |
| Uses |
A major chemical mutagen. Incorporates into DNA, altering base-pair sequencing by replacing thymine |
| Definition |
ChEBI: A pyrimidine having keto groups at the 2- and 4-positions and a bromo group at the 5-position. |
| General Description |
White powder. |
| Air & Water Reactions |
Insoluble in water. |
| Reactivity Profile |
A halogenated amide. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx). |
| Hazard |
Moderately toxic, alters DNA by replacing thymine. |
| Health Hazard |
ACUTE/CHRONIC HAZARDS: When heated to decomposition 5-Bromouracil emits very toxic fumes of bromide ion and NOx. |
| Fire Hazard |
Flash point data for 5-Bromouracil are not available, but 5-Bromouracil is probably combustible. |
| Safety Profile |
Moderately toxic by intraperitoneal route. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of Brand NOx. |
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| 5-Bromouracil Preparation Products And Raw materials |
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About US
Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research. Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products. Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation. We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.
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