China Manufacturer factory sales Hydroxyecdysone CAS 5289-74-7 CAS NO.5289-74-7

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Hydroxyecdysone Basic information Product Name: Hydroxyecdysone Synonyms: BETA-ECDYSONE;BETA-ECDYSONE,2,3,14,20,22,25-HEXAHYDROXY-7-CHOLESTEN-6-ONE;BETA-ECDYSTERONE;7,(5B)-CHOLESTEN-2BETA, 3BETA, 14ALPHA, 20BETA, 22R, 25-HEXOL-6-ONE;2B,3B,14A,20,22[R],25-HEXAHYDROXY-7-CHOLESTEN-6-ONE;2b,3b,14a,20b,22,25-hexahydroxycholest-7-en-6-one;2BETA,3BETA,14ALPHA,20BETA,22,25-HEXAHYDROXY-7-CHOLESTEN-6-ONE;(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-TRIHYDROXY-10,13-DIMETHYL-17-((1R,2R)-1,2,5-TRIHYDROXY-1,5-DIMETHYL-HEXYL)-1,2,3,4,5,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-6-ONE CAS: 5289-74-7 MF: C27H44O7 MW: 480.64 EINECS: 811-097-1 Product Categories: Miscellaneous Natural Products;Steroids;Natural Plant Extract;sy;Herb extract;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors Mol File: 5289-74-7.mol   Hydroxyecdysone Chemical Properties Melting point  242-244 °C Boiling point  498.63°C (rough estimate) density  1.0760 (rough estimate) refractive index  1.5800 (estimate) storage temp.  Sealed in dry,Store in freezer, under -20°C solubility  alcohol: soluble form  powder pka 14.13±0.70(Predicted) color  white Merck  13,3525 BRN  1917578 InChIKey NKDFYOWSKOHCCO-YPVLXUMRSA-N CAS DataBase Reference 5289-74-7(CAS DataBase Reference)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  22-24/25-36-26 WGK Germany  2 RTECS  FZ8060000 F  10 HS Code  29372900 MSDS Information Provider Language 20-Hydroxyecdysone English SigmaAldrich English   Hydroxyecdysone Usage And Synthesis Chemical Properties White or off-white powder Uses insect molting hormone Uses 20-Hydroxyecdysone has been used: in Leibovitz′s dissecting medium for culturing sorting zone and neuropil-associated glia and antennal lobes of Manduca sexta in Schneider′s medium to reproduce ex-vivo imaginal disc eversion as a supplement in Mcl8 medium for culturing Drosophila wing imaginal discs Definition ChEBI: An ecdysteroid that is ecdysone substituted by a hydroxy group at position 20. Biochem/physiol Actions 20-Hydroxyecdysone is an ecdysteroid hormone that plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene expression involved in molting and metamorphosis. It acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins (USP). Purification Methods Crystallise -ecdyson from water, tetrahydrofuran/pet ether, MeOH and EtOAc after chromatographic purification. It has max (EtOH) at 240nm ( 12,670 M-1cm-1). [Also IR & NMR: Hüppi & Siddall J Am Chem Soc 89 6799 1967, Kametani et al. Tetrahedron Lett 21 4855 1980, Beilstein 8 IV 343.]   Hydroxyecdysone Preparation Products And Raw materials

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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Hydroxyecdysone Basic information Product Name: Hydroxyecdysone Synonyms: BETA-ECDYSONE;BETA-ECDYSONE,2,3,14,20,22,25-HEXAHYDROXY-7-CHOLESTEN-6-ONE;BETA-ECDYSTERONE;7,(5B)-CHOLESTEN-2BETA, 3BETA, 14ALPHA, 20BETA, 22R, 25-HEXOL-6-ONE;2B,3B,14A,20,22[R],25-HEXAHYDROXY-7-CHOLESTEN-6-ONE;2b,3b,14a,20b,22,25-hexahydroxycholest-7-en-6-one;2BETA,3BETA,14ALPHA,20BETA,22,25-HEXAHYDROXY-7-CHOLESTEN-6-ONE;(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-TRIHYDROXY-10,13-DIMETHYL-17-((1R,2R)-1,2,5-TRIHYDROXY-1,5-DIMETHYL-HEXYL)-1,2,3,4,5,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-6-ONE CAS: 5289-74-7 MF: C27H44O7 MW: 480.64 EINECS: 811-097-1 Product Categories: Miscellaneous Natural Products;Steroids;Natural Plant Extract;sy;Herb extract;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors Mol File: 5289-74-7.mol   Hydroxyecdysone Chemical Properties Melting point  242-244 °C Boiling point  498.63°C (rough estimate) density  1.0760 (rough estimate) refractive index  1.5800 (estimate) storage temp.  Sealed in dry,Store in freezer, under -20°C solubility  alcohol: soluble form  powder pka 14.13±0.70(Predicted) color  white Merck  13,3525 BRN  1917578 InChIKey NKDFYOWSKOHCCO-YPVLXUMRSA-N CAS DataBase Reference 5289-74-7(CAS DataBase Reference)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  22-24/25-36-26 WGK Germany  2 RTECS  FZ8060000 F  10 HS Code  29372900 MSDS Information Provider Language 20-Hydroxyecdysone English SigmaAldrich English   Hydroxyecdysone Usage And Synthesis Chemical Properties White or off-white powder Uses insect molting hormone Uses 20-Hydroxyecdysone has been used: in Leibovitz′s dissecting medium for culturing sorting zone and neuropil-associated glia and antennal lobes of Manduca sexta in Schneider′s medium to reproduce ex-vivo imaginal disc eversion as a supplement in Mcl8 medium for culturing Drosophila wing imaginal discs Definition ChEBI: An ecdysteroid that is ecdysone substituted by a hydroxy group at position 20. Biochem/physiol Actions 20-Hydroxyecdysone is an ecdysteroid hormone that plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene expression involved in molting and metamorphosis. It acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins (USP). Purification Methods Crystallise -ecdyson from water, tetrahydrofuran/pet ether, MeOH and EtOAc after chromatographic purification. It has max (EtOH) at 240nm ( 12,670 M-1cm-1). [Also IR & NMR: Hüppi & Siddall J Am Chem Soc 89 6799 1967, Kametani et al. Tetrahedron Lett 21 4855 1980, Beilstein 8 IV 343.]   Hydroxyecdysone Preparation Products And Raw materials