China Largest Manufacturer factory sales Gentiobiose CAS 554-91-6 CAS NO.554-91-6

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GENTIOBIOSE Basic information Product Name: GENTIOBIOSE Synonyms: 6-O-beta-D-Glucopyranosyl-D-glucose, Amygdalose;BETA-GENTOBIOSE;BETA-GENTIOBIOSE;BETA-D-GENTIOBIOSE;B-D-GENTIOBIOSE;GENTIOBIOSE;Gentiobiose, for biochemistry, 95%;D-Glucose, 6-O-.beta.-D-glucopyranosyl- CAS: 554-91-6 MF: C12H22O11 MW: 342.3 EINECS: 209-074-0 Product Categories: Basic Sugars (Mono & Oligosaccharides);Biochemistry;Disaccharides;Sugars;Dextrins、Sugar & Carbohydrates;Other APIs;carbohydrate Mol File: 554-91-6.mol   GENTIOBIOSE Chemical Properties Melting point  195-197 °C (dec.) Boiling point  397.76°C (rough estimate) density  1.4149 (rough estimate) refractive index  9.5 ° (C=4, H2O) storage temp.  Sealed in dry,2-8°C form  Powder pka 12.45±0.20(Predicted) color  White to Off-white Water Solubility  Slightly soluble in water. Merck  14,4396 BRN  93354 CAS DataBase Reference 554-91-6(CAS DataBase Reference)   Safety Information WGK Germany  3 F  3-10 HS Code  29400090 MSDS Information Provider Language SigmaAldrich English   GENTIOBIOSE Usage And Synthesis Chemical Properties white to off-white fine crystalline powder Uses A disaccharide composed of two units of D-glucose Uses Gentiobiose was used in binding assays to determine if coelomic cytolytic factor 1 (CCF-1) binds to β-1,3-glucans to stimulate the pro-PO-activating system. Purification Methods -Gentiobiose is best purified via the octaacetate which is recrystallised from MeOH, EtOH or better from methyl cellosolve by heating at 80o. The octaacetate (15g) is hydrolysed by suspending it in dry 0.05N NaOMe in MeOH (180mL) for 1hour with occasional shaking at room temperature. Dilute this with H2O to dissolve suspended matter, pass through Amberlite IR-120 and Duolite A-4 columns and the eluate is evaporated under reduced pressure to a syrup. Residual H2O is removed by repeated distillation with absolute EtOH under reduced pressure. The syrup is dissolved in methyl cellosolve (~40mL), filtered, nucleated and placed in an oven at 80o. The crystals are filtered off, washed with absolute EtOH (yield 6.7g, 89%), dried and have m 187-189o. Further recrystallisation from methyl cellosolve gives m 190o, and mutarotates from [] D 28 -1.5o (initial) to +10.6o (final, c 4, H2O). The -octaacetate has m 193o (crystallised from 95% EtOH) and has [] D 20 -5o (c 1.8, CHCl3). [Goldstein & Whelan Methods in Carbohydrate Chemistry I 313 1962, Academic Press, Beilstein 17/7 V 203.]   GENTIOBIOSE Preparation Products And Raw materials

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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GENTIOBIOSE Basic information Product Name: GENTIOBIOSE Synonyms: 6-O-beta-D-Glucopyranosyl-D-glucose, Amygdalose;BETA-GENTOBIOSE;BETA-GENTIOBIOSE;BETA-D-GENTIOBIOSE;B-D-GENTIOBIOSE;GENTIOBIOSE;Gentiobiose, for biochemistry, 95%;D-Glucose, 6-O-.beta.-D-glucopyranosyl- CAS: 554-91-6 MF: C12H22O11 MW: 342.3 EINECS: 209-074-0 Product Categories: Basic Sugars (Mono & Oligosaccharides);Biochemistry;Disaccharides;Sugars;Dextrins、Sugar & Carbohydrates;Other APIs;carbohydrate Mol File: 554-91-6.mol   GENTIOBIOSE Chemical Properties Melting point  195-197 °C (dec.) Boiling point  397.76°C (rough estimate) density  1.4149 (rough estimate) refractive index  9.5 ° (C=4, H2O) storage temp.  Sealed in dry,2-8°C form  Powder pka 12.45±0.20(Predicted) color  White to Off-white Water Solubility  Slightly soluble in water. Merck  14,4396 BRN  93354 CAS DataBase Reference 554-91-6(CAS DataBase Reference)   Safety Information WGK Germany  3 F  3-10 HS Code  29400090 MSDS Information Provider Language SigmaAldrich English   GENTIOBIOSE Usage And Synthesis Chemical Properties white to off-white fine crystalline powder Uses A disaccharide composed of two units of D-glucose Uses Gentiobiose was used in binding assays to determine if coelomic cytolytic factor 1 (CCF-1) binds to β-1,3-glucans to stimulate the pro-PO-activating system. Purification Methods -Gentiobiose is best purified via the octaacetate which is recrystallised from MeOH, EtOH or better from methyl cellosolve by heating at 80o. The octaacetate (15g) is hydrolysed by suspending it in dry 0.05N NaOMe in MeOH (180mL) for 1hour with occasional shaking at room temperature. Dilute this with H2O to dissolve suspended matter, pass through Amberlite IR-120 and Duolite A-4 columns and the eluate is evaporated under reduced pressure to a syrup. Residual H2O is removed by repeated distillation with absolute EtOH under reduced pressure. The syrup is dissolved in methyl cellosolve (~40mL), filtered, nucleated and placed in an oven at 80o. The crystals are filtered off, washed with absolute EtOH (yield 6.7g, 89%), dried and have m 187-189o. Further recrystallisation from methyl cellosolve gives m 190o, and mutarotates from [] D 28 -1.5o (initial) to +10.6o (final, c 4, H2O). The -octaacetate has m 193o (crystallised from 95% EtOH) and has [] D 20 -5o (c 1.8, CHCl3). [Goldstein & Whelan Methods in Carbohydrate Chemistry I 313 1962, Academic Press, Beilstein 17/7 V 203.]   GENTIOBIOSE Preparation Products And Raw materials