China Biggest Manufacturer factory sales Cytidine CAS 65-46-3 CAS NO.65-46-3

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Cytidine Basic information Product Name: Cytidine Synonyms: Cytidine,Cytosine β-D-riboside, Cytosine-1-β-D-ribofuranoside;Cytidine, 99+% 10GR;Cytidine, 99+% 50GR;1-β-D-ribosylcytosine;4-aMino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)pyriMidin-2(1H)-one;Cytidin;Cytosine, 1-beta-D-ribofuranosyl-;Cytosine β-D-riboside CAS: 65-46-3 MF: C9H13N3O5 MW: 243.22 EINECS: 200-610-9 Product Categories: Biochemistry;Nucleosides and their analogs;FINE Chemical & INTERMEDIATES;Pyridines, Pyrimidines, Purines and Pteredines;Nucleosides, Nucleotides & Related Reagents;Nucleic acids;Pharmaceutical Intermediates;Bases & Related Reagents;Carbohydrates & Derivatives;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;nucleoside;Inhibitors Mol File: 65-46-3.mol   Cytidine Chemical Properties Melting point  210-220 °C (dec.) (lit.) alpha  31.5 º (c=0.6, H2O 25 ºC) Boiling point  386.09°C (rough estimate) density  1.3686 (rough estimate) refractive index  34 ° (C=0.7, H2O) storage temp.  2-8°C solubility  H2O: 50 mg/mL pka 4.22, 12.5(at 25℃) form  powder color  White to almost white optical activity [α]20/D +33°, c = 2 in H2O Water Solubility  SOLUBLE Sensitive  Hygroscopic Merck  14,2786 BRN  89173 Stability: Stable. Incompatible with strong oxidizing agents. Protect from moisture. CAS DataBase Reference 65-46-3(CAS DataBase Reference) NIST Chemistry Reference Cytidine(65-46-3) EPA Substance Registry System Cytidine (65-46-3)   Safety Information Risk Statements  68 Safety Statements  24/25 WGK Germany  3 RTECS  UW7370000 F  10-23 TSCA  Yes HS Code  29349990 Toxicity LD50 intraperitoneal in mouse: 2700mg/kg MSDS Information Provider Language Cytidine English   Cytidine Usage And Synthesis Description Cytidine is a pyrimidine nucleoside that is composed of the pyrimidine base cytosine attached to the sugar ribose. As a constituent of RNA, cytidine pairs with guanine, and it is a precursor of uridine. Cytidine can incur several modifications in mRNA, including methylation and acetylation, that function to regulate translation. Cytidine can also be formylated to 5-formylcytidine in mitochondrial methionine transfer RNA (tRNAMet). Chemical Properties White crystalline powder Uses A constituent of nucleic acids. It was isolated from yeast nucleic acid. Uses Cytidine is a nucleoside molecule that is formed when cytosine is attached to a ribose ring, cytidine is a component of RNA. Uses increases cell membrane phospholipids Definition ChEBI: A pyrimidine nucleoside in which cytosine is attached to ribofuranose via a beta-N1-glycosidic bond. Definition A NUCLEOSIDE formed when cytosine is linked to D-ribose via a β-glycosidic bond. Definition cytidine: A nucleoside comprisingone cytosine molecule linked to a dribosesugar molecule. The derivednucleotides, cytidine mono-, di-, andtriphosphate (CMP, CDP, and CTP respectively)participate in various biochemicalreactions, notably inphospholipid synthesis. General Description White crystalline powder. Air & Water Reactions Cytidine is hygroscopic. Water soluble. Reactivity Profile Cytidine is incompatible with strong oxidizing agents. . Will react as a weak base. Fire Hazard Flash point data for Cytidine are not available; however, Cytidine is probably combustible. Purification Methods Cytidine crystallises from 90% aqueous EtOH. It has also been converted to sulfate by dissolving (~200mg) in a solution of EtOH (10mL) containing H2SO4 (50mg), whereby the salt crystallises out. It is collected, washed with EtOH and dried for 5hours at 120o/0.1mm. The sulfate has m 225o. The free base is obtained by shaking the salt solution with a weak ion-exchange resin, filtering, evaporating and recrystallising the residue from EtOH as before. [Fox & Goodman J Am Chem Soc 73 3256 1956, Fox & Shugar Biochim Biophys Acta 9 369 1952; see Prytsas & Sorm in Synthetic Procedures in Nucleic Acid Chemistry (Zorbach & Tipson Eds) Vol 1 404 1973.] [Beilstein 25 III/IV 3667.]   Cytidine Preparation Products And Raw materials Preparation Products Calcium 5'-ribonucleotide-->1-beta-D-Arabinofuranosylcytosine hydrochloride-->Zalcitabine-->N4-Benzoylcytidine-->CYTIDINE 3'-MONOPHOSPHATE-->3-METHYL URIDINE-->5-Iodocytidine-->N4-Acetylcytidine-->(+)-3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)cytidine

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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Cytidine Basic information Product Name: Cytidine Synonyms: Cytidine,Cytosine β-D-riboside, Cytosine-1-β-D-ribofuranoside;Cytidine, 99+% 10GR;Cytidine, 99+% 50GR;1-β-D-ribosylcytosine;4-aMino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)pyriMidin-2(1H)-one;Cytidin;Cytosine, 1-beta-D-ribofuranosyl-;Cytosine β-D-riboside CAS: 65-46-3 MF: C9H13N3O5 MW: 243.22 EINECS: 200-610-9 Product Categories: Biochemistry;Nucleosides and their analogs;FINE Chemical & INTERMEDIATES;Pyridines, Pyrimidines, Purines and Pteredines;Nucleosides, Nucleotides & Related Reagents;Nucleic acids;Pharmaceutical Intermediates;Bases & Related Reagents;Carbohydrates & Derivatives;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;nucleoside;Inhibitors Mol File: 65-46-3.mol   Cytidine Chemical Properties Melting point  210-220 °C (dec.) (lit.) alpha  31.5 º (c=0.6, H2O 25 ºC) Boiling point  386.09°C (rough estimate) density  1.3686 (rough estimate) refractive index  34 ° (C=0.7, H2O) storage temp.  2-8°C solubility  H2O: 50 mg/mL pka 4.22, 12.5(at 25℃) form  powder color  White to almost white optical activity [α]20/D +33°, c = 2 in H2O Water Solubility  SOLUBLE Sensitive  Hygroscopic Merck  14,2786 BRN  89173 Stability: Stable. Incompatible with strong oxidizing agents. Protect from moisture. CAS DataBase Reference 65-46-3(CAS DataBase Reference) NIST Chemistry Reference Cytidine(65-46-3) EPA Substance Registry System Cytidine (65-46-3)   Safety Information Risk Statements  68 Safety Statements  24/25 WGK Germany  3 RTECS  UW7370000 F  10-23 TSCA  Yes HS Code  29349990 Toxicity LD50 intraperitoneal in mouse: 2700mg/kg MSDS Information Provider Language Cytidine English   Cytidine Usage And Synthesis Description Cytidine is a pyrimidine nucleoside that is composed of the pyrimidine base cytosine attached to the sugar ribose. As a constituent of RNA, cytidine pairs with guanine, and it is a precursor of uridine. Cytidine can incur several modifications in mRNA, including methylation and acetylation, that function to regulate translation. Cytidine can also be formylated to 5-formylcytidine in mitochondrial methionine transfer RNA (tRNAMet). Chemical Properties White crystalline powder Uses A constituent of nucleic acids. It was isolated from yeast nucleic acid. Uses Cytidine is a nucleoside molecule that is formed when cytosine is attached to a ribose ring, cytidine is a component of RNA. Uses increases cell membrane phospholipids Definition ChEBI: A pyrimidine nucleoside in which cytosine is attached to ribofuranose via a beta-N1-glycosidic bond. Definition A NUCLEOSIDE formed when cytosine is linked to D-ribose via a β-glycosidic bond. Definition cytidine: A nucleoside comprisingone cytosine molecule linked to a dribosesugar molecule. The derivednucleotides, cytidine mono-, di-, andtriphosphate (CMP, CDP, and CTP respectively)participate in various biochemicalreactions, notably inphospholipid synthesis. General Description White crystalline powder. Air & Water Reactions Cytidine is hygroscopic. Water soluble. Reactivity Profile Cytidine is incompatible with strong oxidizing agents. . Will react as a weak base. Fire Hazard Flash point data for Cytidine are not available; however, Cytidine is probably combustible. Purification Methods Cytidine crystallises from 90% aqueous EtOH. It has also been converted to sulfate by dissolving (~200mg) in a solution of EtOH (10mL) containing H2SO4 (50mg), whereby the salt crystallises out. It is collected, washed with EtOH and dried for 5hours at 120o/0.1mm. The sulfate has m 225o. The free base is obtained by shaking the salt solution with a weak ion-exchange resin, filtering, evaporating and recrystallising the residue from EtOH as before. [Fox & Goodman J Am Chem Soc 73 3256 1956, Fox & Shugar Biochim Biophys Acta 9 369 1952; see Prytsas & Sorm in Synthetic Procedures in Nucleic Acid Chemistry (Zorbach & Tipson Eds) Vol 1 404 1973.] [Beilstein 25 III/IV 3667.]   Cytidine Preparation Products And Raw materials Preparation Products Calcium 5'-ribonucleotide-->1-beta-D-Arabinofuranosylcytosine hydrochloride-->Zalcitabine-->N4-Benzoylcytidine-->CYTIDINE 3'-MONOPHOSPHATE-->3-METHYL URIDINE-->5-Iodocytidine-->N4-Acetylcytidine-->(+)-3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)cytidine