China Largest Manufacturer factory Supply n-Docosanol/Behenyl Alcohol/1-Docosanol CAS 661-19-8 CAS NO.661-19-8

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n-Docosanol Basic information Product Name: n-Docosanol Synonyms: ALCOHOL C22;BEHENYLIC ALCOHOL;Behenic alcohol;behenicalcohol;Cachalot BE-22;Dehydag wax 22 (lanette);Docosan-1-ol;Docosanol-(1) CAS: 661-19-8 MF: C22H46O MW: 326.6 EINECS: 211-546-6 Product Categories: ABREVA;Pharmaceutical Raw Materials;Saturated Higher Alcohols;1-Alkanols;Antivirals for Research and Experimental Use;Biochemistry;Higher Fatty Acids & Higher Alcohols;Monofunctional & alpha,omega-Bifunctional Alkanes;Monofunctional Alkanes;Pharma material;fine chemicals;Inhibitors;661-19-8 Mol File: 661-19-8.mol   n-Docosanol Chemical Properties Melting point  65-72 °C(lit.) Boiling point  180 °C0.22 mm Hg(lit.) density  d75 0.8063 g/ml; d85 0.7986 g/ml; d95 0.7911 g/ml refractive index  n75 1.4360 storage temp.  Store below +30°C. solubility  Chloroform (Slightly), Ethyl Acetate (Slightly) pka 15.20±0.10(Predicted) form  Pellets or Tablets color  White Water Solubility  Insoluble Merck  13,3433 BRN  1770470 Stability: Stable. Combustible. Incompatible with strong oxidizing agents. CAS DataBase Reference 661-19-8(CAS DataBase Reference) NIST Chemistry Reference 1-Docosanol(661-19-8) EPA Substance Registry System 1-Docosanol (661-19-8)   Safety Information Safety Statements  24/25 WGK Germany  - RTECS  JR1315000 TSCA  Yes HS Code  29051900 Hazardous Substances Data 661-19-8(Hazardous Substances Data) Toxicity LD50 intraperitoneal in mouse: > 800mg/kg MSDS Information Provider Language 1-Docosanol English ACROS English SigmaAldrich English ALFA English   n-Docosanol Usage And Synthesis Chemical Properties 1-DOCOSANOL is white powder Uses antiviral Uses n-Docosanol is a binder and an emulsion stabilizer. It is also used to increase a formulation’s viscosity. This is a mixture of fatty alcohols. behenyl alcohol may be used for any number of purposes in a cosmetic formulation, including as an emollient, a binder, an emulsion stabilizer, or to increase a product’s viscosity. It may be derived either synthetically or from plants. Uses 1-Docosanol works as a surfactant in cosmetics. 1-Docosanol cream has also been approved by the US Food and Drug Administration as a safe and effective topical treatment for herpes labialis Indications Docosanol (Abreva) is a long-chain saturated alcohol that is clinically effective against HSV. It has in vitro activity against many enveloped viruses, including CMV, influenzavirus, and respiratory syncytial virus. Docosanol is not directly virucidal; instead, it blocks the entry of the virion into the host cell by inhibiting the fusion of the viral envelope with the host plasma membrane. Because it does not affect viral replication or protein production, it may be less susceptible to the development of resistance than other antiviral drugs. Definition 1-DOCOSANOL is a  long-chain, saturated fatty alcohol. General Description 1-Docosanol inhibits replication of certain viruses (herpes simplex virus and respiratory syncytial virus) within primary target cells in vitro. It has been isolated from Clematis brevicaudata. Pharmaceutical Applications 1-DOCOSANOL is a 22-carbon straight chain alcohol licensed for over-thecounter sales for the topical treatment of herpes labialis. It is thought to act by blocking viral fusion with the host cell, although definitive studies are lacking. The clinical relevance of the antiviral activity has been debated and the place of this medication as a treatment of herpes labialis remains to be established. Clinical Use Docosanol cream is approved for the over-the-counter treatment of herpes labialis. It shortens the duration of symptoms of cold sores and fever blisters but does not provide symptomatic relief. Side effects Adverse effects of docosanol are minimal. Skin irritation occurs infrequently. Drug interactions are not anticipated. Purification Methods Crystallise docosanol from ether or chloroform/ether. [Beilstein 1 IV 1906.]   n-Docosanol Preparation Products And Raw materials Preparation Products N-TETRATETRACONTANE

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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n-Docosanol Basic information Product Name: n-Docosanol Synonyms: ALCOHOL C22;BEHENYLIC ALCOHOL;Behenic alcohol;behenicalcohol;Cachalot BE-22;Dehydag wax 22 (lanette);Docosan-1-ol;Docosanol-(1) CAS: 661-19-8 MF: C22H46O MW: 326.6 EINECS: 211-546-6 Product Categories: ABREVA;Pharmaceutical Raw Materials;Saturated Higher Alcohols;1-Alkanols;Antivirals for Research and Experimental Use;Biochemistry;Higher Fatty Acids & Higher Alcohols;Monofunctional & alpha,omega-Bifunctional Alkanes;Monofunctional Alkanes;Pharma material;fine chemicals;Inhibitors;661-19-8 Mol File: 661-19-8.mol   n-Docosanol Chemical Properties Melting point  65-72 °C(lit.) Boiling point  180 °C0.22 mm Hg(lit.) density  d75 0.8063 g/ml; d85 0.7986 g/ml; d95 0.7911 g/ml refractive index  n75 1.4360 storage temp.  Store below +30°C. solubility  Chloroform (Slightly), Ethyl Acetate (Slightly) pka 15.20±0.10(Predicted) form  Pellets or Tablets color  White Water Solubility  Insoluble Merck  13,3433 BRN  1770470 Stability: Stable. Combustible. Incompatible with strong oxidizing agents. CAS DataBase Reference 661-19-8(CAS DataBase Reference) NIST Chemistry Reference 1-Docosanol(661-19-8) EPA Substance Registry System 1-Docosanol (661-19-8)   Safety Information Safety Statements  24/25 WGK Germany  - RTECS  JR1315000 TSCA  Yes HS Code  29051900 Hazardous Substances Data 661-19-8(Hazardous Substances Data) Toxicity LD50 intraperitoneal in mouse: > 800mg/kg MSDS Information Provider Language 1-Docosanol English ACROS English SigmaAldrich English ALFA English   n-Docosanol Usage And Synthesis Chemical Properties 1-DOCOSANOL is white powder Uses antiviral Uses n-Docosanol is a binder and an emulsion stabilizer. It is also used to increase a formulation’s viscosity. This is a mixture of fatty alcohols. behenyl alcohol may be used for any number of purposes in a cosmetic formulation, including as an emollient, a binder, an emulsion stabilizer, or to increase a product’s viscosity. It may be derived either synthetically or from plants. Uses 1-Docosanol works as a surfactant in cosmetics. 1-Docosanol cream has also been approved by the US Food and Drug Administration as a safe and effective topical treatment for herpes labialis Indications Docosanol (Abreva) is a long-chain saturated alcohol that is clinically effective against HSV. It has in vitro activity against many enveloped viruses, including CMV, influenzavirus, and respiratory syncytial virus. Docosanol is not directly virucidal; instead, it blocks the entry of the virion into the host cell by inhibiting the fusion of the viral envelope with the host plasma membrane. Because it does not affect viral replication or protein production, it may be less susceptible to the development of resistance than other antiviral drugs. Definition 1-DOCOSANOL is a  long-chain, saturated fatty alcohol. General Description 1-Docosanol inhibits replication of certain viruses (herpes simplex virus and respiratory syncytial virus) within primary target cells in vitro. It has been isolated from Clematis brevicaudata. Pharmaceutical Applications 1-DOCOSANOL is a 22-carbon straight chain alcohol licensed for over-thecounter sales for the topical treatment of herpes labialis. It is thought to act by blocking viral fusion with the host cell, although definitive studies are lacking. The clinical relevance of the antiviral activity has been debated and the place of this medication as a treatment of herpes labialis remains to be established. Clinical Use Docosanol cream is approved for the over-the-counter treatment of herpes labialis. It shortens the duration of symptoms of cold sores and fever blisters but does not provide symptomatic relief. Side effects Adverse effects of docosanol are minimal. Skin irritation occurs infrequently. Drug interactions are not anticipated. Purification Methods Crystallise docosanol from ether or chloroform/ether. [Beilstein 1 IV 1906.]   n-Docosanol Preparation Products And Raw materials Preparation Products N-TETRATETRACONTANE