China Largest Factory Manufacturer sales 4-Hydroxybenzylamine CAS 696-60-6 CAS NO.696-60-6

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4-Hydroxybenzylamine Basic information Product Name: 4-Hydroxybenzylamine Synonyms: RARECHEM AL BW 0048;4-HYDROXYBENZYLAMINE[4-(AMINOMETHYL)PHENOL];4-(AMINOMETHYL)PHENOL;4-HYDROXYBENZYLAMINE;4-Hydroxybenzylamine, (4-Hydroxyphenyl)methylamine;4-(aminomethyl)phenol hydrochloride;4-Hydroxybenzylamine monohydrate, 97%;[(4-Hydroxyphenyl)Methyl]aMine CAS: 696-60-6 MF: C7H9NO MW: 123.15 EINECS:   Product Categories: Amines;Aromatics;Anilines, Aromatic Amines and Nitro Compounds;Intermediates Mol File: 696-60-6.mol   4-Hydroxybenzylamine Chemical Properties Melting point  123-128 °C Boiling point  262.4±15.0 °C(Predicted) density  1.141±0.06 g/cm3(Predicted) storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C solubility  DMSO (Slightly), Water (Slightly, Heated) pka 8.93±0.26(Predicted) form  Powder color  Off-white to pale yellow InChIKey RQJDUEKERVZLLU-UHFFFAOYSA-N CAS DataBase Reference 696-60-6(CAS DataBase Reference)   Safety Information Hazard Codes  Xi Risk Statements  34-36/37/38 Safety Statements  26-36/37/39-24/25 RIDADR  2735 WGK Germany  3 Hazard Note  Irritant HazardClass  IRRITANT, CORROSIVE HS Code  29214990 MSDS Information   4-Hydroxybenzylamine Usage And Synthesis Description 4-HOBA is an isomer of the isoketal scavenger 2-HOBA (Item No. 25357) that has reduced efficacy as an isoketal scavenger. Unlike 2-HOBA, 4-HOBA has no effect on hypertension induced by angiotensin II (Item No. 17150) in mice. 4-HOBA has been used as a negative control for the activity of 2-HOBA and related compounds in a mouse model of hypertension. Chemical Properties 4-Hydroxybenzylamine, also known as tyramine and p-hydroxyphenethylamine, is a white or off-white or light green solid. Tyramine, a compound originally isolated from ergot alkaloids and decomposed animal tissues, is an important synthetic drug intermediate. Uses 4-Hydroxybenzylamine (cas# 696-60-6) is a compound useful in organic synthesis. Preparation Synthesis of 4-Hydroxybenzylamine:Ammonia is passed into 500 ml of ethanol at 10° C. until saturation is reached, 122.1 g=1 mole of p-hydroxybenzaldehyde, 20 g of Raney nickel and 0.1 ml of concentrated sulfuric acid are added and the mixture is stirred in an autoclave for 6 hours at room temperature and under a hydrogen pressure of 100 atmospheres. After releasing the pressure, the catalyst is filtered off and the filtrate is boiled up with active charcoal, filtered and concentrated. The residue is recrystallized from a mixture of ethanol and ether. This gives 104 g (85% of theory), melting point: 104° C. Literature source US04391805   4-Hydroxybenzylamine Preparation Products And Raw materials Preparation Products 4-[2-(DIMETHYLAMINO)ETHOXY]BENZYLAMINE

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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4-Hydroxybenzylamine Basic information Product Name: 4-Hydroxybenzylamine Synonyms: RARECHEM AL BW 0048;4-HYDROXYBENZYLAMINE[4-(AMINOMETHYL)PHENOL];4-(AMINOMETHYL)PHENOL;4-HYDROXYBENZYLAMINE;4-Hydroxybenzylamine, (4-Hydroxyphenyl)methylamine;4-(aminomethyl)phenol hydrochloride;4-Hydroxybenzylamine monohydrate, 97%;[(4-Hydroxyphenyl)Methyl]aMine CAS: 696-60-6 MF: C7H9NO MW: 123.15 EINECS:   Product Categories: Amines;Aromatics;Anilines, Aromatic Amines and Nitro Compounds;Intermediates Mol File: 696-60-6.mol   4-Hydroxybenzylamine Chemical Properties Melting point  123-128 °C Boiling point  262.4±15.0 °C(Predicted) density  1.141±0.06 g/cm3(Predicted) storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C solubility  DMSO (Slightly), Water (Slightly, Heated) pka 8.93±0.26(Predicted) form  Powder color  Off-white to pale yellow InChIKey RQJDUEKERVZLLU-UHFFFAOYSA-N CAS DataBase Reference 696-60-6(CAS DataBase Reference)   Safety Information Hazard Codes  Xi Risk Statements  34-36/37/38 Safety Statements  26-36/37/39-24/25 RIDADR  2735 WGK Germany  3 Hazard Note  Irritant HazardClass  IRRITANT, CORROSIVE HS Code  29214990 MSDS Information   4-Hydroxybenzylamine Usage And Synthesis Description 4-HOBA is an isomer of the isoketal scavenger 2-HOBA (Item No. 25357) that has reduced efficacy as an isoketal scavenger. Unlike 2-HOBA, 4-HOBA has no effect on hypertension induced by angiotensin II (Item No. 17150) in mice. 4-HOBA has been used as a negative control for the activity of 2-HOBA and related compounds in a mouse model of hypertension. Chemical Properties 4-Hydroxybenzylamine, also known as tyramine and p-hydroxyphenethylamine, is a white or off-white or light green solid. Tyramine, a compound originally isolated from ergot alkaloids and decomposed animal tissues, is an important synthetic drug intermediate. Uses 4-Hydroxybenzylamine (cas# 696-60-6) is a compound useful in organic synthesis. Preparation Synthesis of 4-Hydroxybenzylamine:Ammonia is passed into 500 ml of ethanol at 10° C. until saturation is reached, 122.1 g=1 mole of p-hydroxybenzaldehyde, 20 g of Raney nickel and 0.1 ml of concentrated sulfuric acid are added and the mixture is stirred in an autoclave for 6 hours at room temperature and under a hydrogen pressure of 100 atmospheres. After releasing the pressure, the catalyst is filtered off and the filtrate is boiled up with active charcoal, filtered and concentrated. The residue is recrystallized from a mixture of ethanol and ether. This gives 104 g (85% of theory), melting point: 104° C. Literature source US04391805   4-Hydroxybenzylamine Preparation Products And Raw materials Preparation Products 4-[2-(DIMETHYLAMINO)ETHOXY]BENZYLAMINE