Hot Sales!!!!!!!!!+China Biggest Manufacturer supply Fusidic Acid CAS NO.6990-06-3

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Fusidine Basic information Mode of action Product Name: Fusidine Synonyms: 4-alpha,8-alpha,9-beta,11-alpha,13-alpha,14-beta,16-beta,17z)-ph;ramycin;sq16603;(3ALPHA,4ALPHA,8ALPHA,9BETA,11ALPHA,13ALPHA,14BETA,16BETA,17Z)-16-(ACETYLOXY)-3,11-DIHYDROXY-29-NORDAMMARA-17(20),24-DIEN-21-OIC ACID;FUSIDIC ACID;29-NordaMMara-17(20),24-dien-21-oicacid, 16-(acetyloxy)-3,11-dihydroxy-, (3a,4a,8a,9b,11a,13a,14b,16b,17Z)-;Fusidic acid for peak identification;Fusidic acid, 98.5% CAS: 6990-06-3 MF: C31H48O6 MW: 516.72 EINECS: 230-256-0 Product Categories: Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;API;FUCIDINE;antibiotic;Steroids;E-FCell Signaling and Neuroscience;Gene Regulation and Expression;RNA-Protein Translation Inhibitors;Stains and Dyes;Stains&Dyes, A to Mol File: 6990-06-3.mol   Fusidine Chemical Properties Melting point  190-192°C alpha  D20 -9° (chloroform) Boiling point  521.49°C (rough estimate) density  1.0389 (rough estimate) refractive index  1.4890 (estimate) storage temp.  Sealed in dry,2-8°C solubility  Practically insoluble in water, freely soluble in ethanol (96 per cent) form  neat pka pK: 5.35 in water color  White to Off-White λmax 204nm(H2O)(lit.) Merck  14,4317 Stability: Hygroscopic CAS DataBase Reference 6990-06-3(CAS DataBase Reference)   Safety Information Hazard Codes  Xn Risk Statements  22 Safety Statements  36 WGK Germany  3 RTECS  RC1350000 HS Code  29419000 Toxicity LD50 in mice (g/kg): 1.2 s.c.; 1.5 orally (Godtfredsen) MSDS Information Provider Language Fusidine English   Fusidine Usage And Synthesis Mode of action Fusidic acid forms a stable complex with an elongation factor (EF-G) involved in translocation and with guanosine triphosphate (GTP), which provides energy for the translocation process. One round of translocation occurs, with hydrolysis of GTP, but the fusidic acid–EF-G–GDP complex cannot dissociate from the ribosome, thereby blocking further chain elongation and leaving peptidyl-tRNA in the P site. Although protein synthesis in Gram-negative bacilli–and, indeed, mammalian cells–is susceptible to fusidic acid, the antibiotic penetrates poorly into these cells and the spectrum of action is virtually restricted to Gram-positive bacteria, notably staphylococci. Chemical Properties White Solid Uses Fusidic acid is a bacteriostatic antibiotic. Fusidic Acid suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA. Uses antibacterial Uses Fusidic acid is a bacteriostatic antibiotic. Fusidic Acid suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA. Dyes and metabolites. Definition ChEBI: A steroid antibiotic that is isolated from the fermentation broth of Fusidium coccineum. Brand name Fucidine (Bristol-Myers Squibb). Hazard Moderately toxic inhibitor of translocation during protein synthesis. Biochem/physiol Actions Fusidic acid is a tetracyclic triterpenoid with antibiotic activity against Gram-positive bacteria. It is derived from Fusidium coccineum. It shows its activity against anaerobes, corynebacterial, Nocardia, and Neisseria species. Fusidic acid exhibits therapeutic effects against Staphylococcal infections, skin infections.   Fusidine Preparation Products And Raw materials

                                Group profiles

Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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                                                       Product information

Fusidine Basic information Mode of action Product Name: Fusidine Synonyms: 4-alpha,8-alpha,9-beta,11-alpha,13-alpha,14-beta,16-beta,17z)-ph;ramycin;sq16603;(3ALPHA,4ALPHA,8ALPHA,9BETA,11ALPHA,13ALPHA,14BETA,16BETA,17Z)-16-(ACETYLOXY)-3,11-DIHYDROXY-29-NORDAMMARA-17(20),24-DIEN-21-OIC ACID;FUSIDIC ACID;29-NordaMMara-17(20),24-dien-21-oicacid, 16-(acetyloxy)-3,11-dihydroxy-, (3a,4a,8a,9b,11a,13a,14b,16b,17Z)-;Fusidic acid for peak identification;Fusidic acid, 98.5% CAS: 6990-06-3 MF: C31H48O6 MW: 516.72 EINECS: 230-256-0 Product Categories: Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;API;FUCIDINE;antibiotic;Steroids;E-FCell Signaling and Neuroscience;Gene Regulation and Expression;RNA-Protein Translation Inhibitors;Stains and Dyes;Stains&Dyes, A to Mol File: 6990-06-3.mol   Fusidine Chemical Properties Melting point  190-192°C alpha  D20 -9° (chloroform) Boiling point  521.49°C (rough estimate) density  1.0389 (rough estimate) refractive index  1.4890 (estimate) storage temp.  Sealed in dry,2-8°C solubility  Practically insoluble in water, freely soluble in ethanol (96 per cent) form  neat pka pK: 5.35 in water color  White to Off-White λmax 204nm(H2O)(lit.) Merck  14,4317 Stability: Hygroscopic CAS DataBase Reference 6990-06-3(CAS DataBase Reference)   Safety Information Hazard Codes  Xn Risk Statements  22 Safety Statements  36 WGK Germany  3 RTECS  RC1350000 HS Code  29419000 Toxicity LD50 in mice (g/kg): 1.2 s.c.; 1.5 orally (Godtfredsen) MSDS Information Provider Language Fusidine English   Fusidine Usage And Synthesis Mode of action Fusidic acid forms a stable complex with an elongation factor (EF-G) involved in translocation and with guanosine triphosphate (GTP), which provides energy for the translocation process. One round of translocation occurs, with hydrolysis of GTP, but the fusidic acid–EF-G–GDP complex cannot dissociate from the ribosome, thereby blocking further chain elongation and leaving peptidyl-tRNA in the P site. Although protein synthesis in Gram-negative bacilli–and, indeed, mammalian cells–is susceptible to fusidic acid, the antibiotic penetrates poorly into these cells and the spectrum of action is virtually restricted to Gram-positive bacteria, notably staphylococci. Chemical Properties White Solid Uses Fusidic acid is a bacteriostatic antibiotic. Fusidic Acid suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA. Uses antibacterial Uses Fusidic acid is a bacteriostatic antibiotic. Fusidic Acid suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA. Dyes and metabolites. Definition ChEBI: A steroid antibiotic that is isolated from the fermentation broth of Fusidium coccineum. Brand name Fucidine (Bristol-Myers Squibb). Hazard Moderately toxic inhibitor of translocation during protein synthesis. Biochem/physiol Actions Fusidic acid is a tetracyclic triterpenoid with antibiotic activity against Gram-positive bacteria. It is derived from Fusidium coccineum. It shows its activity against anaerobes, corynebacterial, Nocardia, and Neisseria species. Fusidic acid exhibits therapeutic effects against Staphylococcal infections, skin infections.   Fusidine Preparation Products And Raw materials