China Largest Manufacturer factory sales 99.9% CP Grade Pyrogallol CAS 87-66-1 CAS NO.87-66-1

                                      PRODUCT DETAILS       

Product name: Pyrogallol

Alias: pyrogallic acid, pyrogallol, pyrogallol
Chemical name: 1,2,3-trihydroxybenzene
Molecular formula: C 6 H 3 (OH) 3
Molecular weight: 126.11

Structural formula:

Property: This product is a white shiny crystalline powder, soluble in 2 parts of water, 1 part of ethanol or 2 parts of ether.

Specifications: in line with the national industry standard LY-T 2862; in line with the US "chemical reagent standards"; Lawson V version and Japanese national standard K8780 reagent specifications.

Technical index:

Uses: Widely used in chemical reagents and chemicals, pharmaceutical intermediates, fine chemicals, new photosensitive materials, food preservation, textile printing and dyeing, light industrial daily chemicals, color printing and plate making, microelectronics industry, rare metal analysis, gas analysis, photo development It can also be used for the analysis and determination of oxygen, antimony, bismuth, cerium, iron, molybdenum, tantalum and niobium.

Storage: Avoid moisture and light, sealed tightly, no contact with metal.

Product validity: two years.

Packing: packed in cardboard drums, net weight 25 kg per drum.

Pyrogallol Basic information Product Name: Pyrogallol Synonyms: 1,2,3-Trihydroxybenzen;1,2,3-trihydroxy-benzen;1,2,3-trihydroxybenzen(czech);1,2,3-trihydroxybenzene(pyrogallol);2,3-Dihydroxyphenol;Benzene, 1,2,3-trihydroxy-;benzene-1,2,3-triol;C.I. Oxidation Base 32 CAS: 87-66-1 MF: C6H6O3 MW: 126.11 EINECS: 201-762-9 Product Categories: ACS Grade;Building Blocks;Chemical Synthesis;Essential Chemicals;Inorganic Salts;Organic Building Blocks;FINE Chemical & INTERMEDIATES;Aromatic Hydrocarbons (substituted) & Derivatives;Oxygen Compounds;Hypericum perforatum (St John′;Nutrition Research;Phytochemicals by Plant (Food/Spice/Herb);s wort);Pharmacopoeia;Polyols;Research Essentials;Solutions and Reagents;Pharmacopoeia A-Z;Food additive , Antioxidant anticorrosive Mol File: 87-66-1.mol   Pyrogallol Chemical Properties Melting point  43-47 °C(lit.) Boiling point  309 °C density  1.112 g/mL at 25 °C(lit.) vapor density  4.4 (vs air) vapor pressure  10 mm Hg ( 167.7 °C) refractive index  n20/D 1.387 Fp  >230 °F storage temp.  Store below +30°C. solubility  water: soluble form  Very Fine Crystalline Powder pka pK1:9.03(0);pK2:11.63(+1) (25°C) color  White PH 4-5 (50g/l, H2O, 20℃) Water Solubility  400 g/L (25 ºC) Sensitive  Light Sensitive Merck  14,8000 BRN  907431 Stability: Stability Stable, but decolourises in light. Combustible. Incompatible with strong oxidising agents, alkalies, metal oxides, ammonia, antipyrine, phenol, iodine, lime water, menthol, potassium permanganate, strong bases. InChIKey WQGWDDDVZFFDIG-UHFFFAOYSA-N CAS DataBase Reference 87-66-1(CAS DataBase Reference) NIST Chemistry Reference 1,2,3-Benzenetriol(87-66-1) EPA Substance Registry System Pyrogallol (87-66-1)   Safety Information Hazard Codes  Xn Risk Statements  20/21/22-52/53-68-40-36/38 Safety Statements  22-24/25-61-36/37-26 RIDADR  UN 2811 6.1/PG 3 WGK Germany  3 RTECS  UX2800000 F  8 TSCA  Yes HS Code  2907 29 00 HazardClass  6.1 PackingGroup  III Hazardous Substances Data 87-66-1(Hazardous Substances Data) Toxicity LD50 orally in rabbits: 1.6 g/kg (Dollahite) MSDS Information Provider Language SigmaAldrich English ACROS English ALFA English   Pyrogallol Usage And Synthesis Description Pyrogallol is a natural oxidant that can generate superoxide (O2-) in alkaline solutions through autoxidation to a semiquinone radical. Importantly, the semiquinone radical can react with O2- in an acidic environment to produce a quinone and H2O2. Pyrogallol autoxidation is used in superoxide dismutase activity assays. It can also be used in assays to assess antioxidant capacity. Pyrogallol is used in some biological systems as an O2- scavenger. In other biological systems, it is used as an O2- generator. Pyrogallol effectively scavenges DPPH radical (Item No. 14805) and ABTS+ in vitro. Pyrogallol is a product of tannin degradation to gallic acid (Item No. 11846) by ruminant microbes and has hepatotoxic and nephrotoxic effects in vivo. Chemical Properties White or nearly white needle- or leaf-shaped crystals or crystalline powder.Pyrogallol is practically odorless. Chemical Properties white crystalline solid Uses Pyrogallol possesses importance as a spectrophotometric reagent in the determination of niobium and tantalum. The absorptions of niobium and tantalum complexes are usually measured at 340 and 335 nm, respectively. The niobium complex is formed in slightly acidic medium, and the tantalum complex in strongly acidic medium (4 N HC1). The absorption spectra are pH-dependen. Uses Complexing agent; reducing agent; alkaline solution indicator for gaseous oxygen. Uses Pyrogallol is used in the manufacture of various dyes; in dyeing furs, hairs, and feathers; for staining leather; in engraving;as a developer in photography; and as an analytical reagent.. Production Methods Pyrogallol is prepared by heating dried gallic acid at about 200°C with the loss of carbon dioxide or by the chlorination of cyclohexanol to tetrachlorocyclohexanone, followed by hydrolysis. Definition ChEBI: A benzenetriol carrying hydroxy groups at positions 1, 2 and 3. General Description Odorless white to gray solid. Sinks and mixes with water. Air & Water Reactions Turns gray on exposure to light or air. Water soluble. Reactivity Profile Pyrogallol is a strong reducing agent. Reacts with alkalis, NH3, antipyrine, camphor, phenol, iron and lead salts, iodine, lime water, menthol and KMnO4. Hazard Toxic by ingestion and skin absorption. Health Hazard The toxic symptoms are similar to those of phenol. It can enter the body by absorption through skin and ingestion. The poisoning effects are nausea, vomiting, gastritis, hemolysis, methemoglobinemia, kidney and liver damage, convulsions, and congestion of lungs. High doses can cause death. Ingestion of 2–3 g of solid can be fatal to humans. The LD50 values varied widely in species. The oral LD50 value in mice is about 300 mg/kg. Health Hazard Inhalation of dust causes irritation of nose and throat. Ingestion may cause severe gastrointestinal irritation, convulsions, circulatory collapse, and death. Contact with eyes causes irritation. Skin contact can cause local discoloration, irritation, eczema, and death; repeated contact can cause sensitization. Fire Hazard Pyrogallol is probably combustible. Contact allergens Pyrogallol belongs to the phenols group. It is an old photograph developer and a low sensitizer in hair dyes. Biochem/physiol Actions Pyrogallol also referred to as 1,2,3-trihydroxybenzene inhibits the response to nitric oxide (NO) in the rat anococcygeus muscle. Safety Profile Human poison by ingestion and subcutaneous routes. An experimental poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. 1 198 PPRSOO PYROSULFURYL CHLORIDE Readdy absorbed through the skin. Human systemic effects by ingestion: convulsions, dyspnea, gastrointestinal effects. A severe skin and eye irritant. Incompatible with alkalies, NH3, antipyrine, phenol, iron and lead salts, iodine, KMn04. When heated to decomposition it emits acrid smoke and irritating fumes. Used as a topical antibacterial agent, as an intermediate, hair dye component, and analytical reagent. Carcinogenicity Pyrogallol was not carcinogenic in mouse and rabbit chronic dermal studies. Mice were treated twice weekly with pyrogallol in acetone (50%) on the shaved flank for life. There was no increase in dermal or systemic tumors. A similar study in rabbits also revealed no skin tumors, although positive controls showed an increase in tumors in both mice and rabbits. Pyrogallol was considered to be cocarcinogenic when administered dermally three times a week together with the skin carcinogen benzo[a]pyrene for 440 days; pyrogallol administered alone caused no increase in skin tumors.   Pyrogallol Preparation Products And Raw materials Preparation Products Atracurium besylate-->1,2,3-Trimethoxybenzene-->Ubidecarenone-->1,4-BUTANEDIOL DIACRYLATE-->4-Hydroxybutyl acrylate-->7,8-DIHYDROXY-4-METHYLCOUMARIN-->Exifone-->BENDIOCARB-->1-CHLOROMETHYL-2,3,4-TRIMETHOXYBENZENE-->Gallamine triethiodide-->1,3-Benzenediol, 2,5-dimethoxy--->GALLEIN-->7,8-Dihydroxyflavone-->7,8-Dihydroxycoumarin-->2'-HYDROXY-3',4'-DIMETHOXYACETOPHENONE-->5-TERT-BUTYLPYROGALLOL-->C.I.Mordant Green 22-->GALLEIN

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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                                                                  Product information

Product name: Pyrogallol

Alias: pyrogallic acid, pyrogallol, pyrogallol
Chemical name: 1,2,3-trihydroxybenzene
Molecular formula: C 6 H 3 (OH) 3
Molecular weight: 126.11

Structural formula:

Property: This product is a white shiny crystalline powder, soluble in 2 parts of water, 1 part of ethanol or 2 parts of ether.

Specifications: in line with the national industry standard LY-T 2862; in line with the US "chemical reagent standards"; Lawson V version and Japanese national standard K8780 reagent specifications.

Technical index:

Pyrogallol Basic information Product Name: Pyrogallol Synonyms: 1,2,3-Trihydroxybenzen;1,2,3-trihydroxy-benzen;1,2,3-trihydroxybenzen(czech);1,2,3-trihydroxybenzene(pyrogallol);2,3-Dihydroxyphenol;Benzene, 1,2,3-trihydroxy-;benzene-1,2,3-triol;C.I. Oxidation Base 32 CAS: 87-66-1 MF: C6H6O3 MW: 126.11 EINECS: 201-762-9 Product Categories: ACS Grade;Building Blocks;Chemical Synthesis;Essential Chemicals;Inorganic Salts;Organic Building Blocks;FINE Chemical & INTERMEDIATES;Aromatic Hydrocarbons (substituted) & Derivatives;Oxygen Compounds;Hypericum perforatum (St John′;Nutrition Research;Phytochemicals by Plant (Food/Spice/Herb);s wort);Pharmacopoeia;Polyols;Research Essentials;Solutions and Reagents;Pharmacopoeia A-Z;Food additive , Antioxidant anticorrosive Mol File: 87-66-1.mol   Pyrogallol Chemical Properties Melting point  43-47 °C(lit.) Boiling point  309 °C density  1.112 g/mL at 25 °C(lit.) vapor density  4.4 (vs air) vapor pressure  10 mm Hg ( 167.7 °C) refractive index  n20/D 1.387 Fp  >230 °F storage temp.  Store below +30°C. solubility  water: soluble form  Very Fine Crystalline Powder pka pK1:9.03(0);pK2:11.63(+1) (25°C) color  White PH 4-5 (50g/l, H2O, 20℃) Water Solubility  400 g/L (25 ºC) Sensitive  Light Sensitive Merck  14,8000 BRN  907431 Stability: Stability Stable, but decolourises in light. Combustible. Incompatible with strong oxidising agents, alkalies, metal oxides, ammonia, antipyrine, phenol, iodine, lime water, menthol, potassium permanganate, strong bases. InChIKey WQGWDDDVZFFDIG-UHFFFAOYSA-N CAS DataBase Reference 87-66-1(CAS DataBase Reference) NIST Chemistry Reference 1,2,3-Benzenetriol(87-66-1) EPA Substance Registry System Pyrogallol (87-66-1)   Safety Information Hazard Codes  Xn Risk Statements  20/21/22-52/53-68-40-36/38 Safety Statements  22-24/25-61-36/37-26 RIDADR  UN 2811 6.1/PG 3 WGK Germany  3 RTECS  UX2800000 F  8 TSCA  Yes HS Code  2907 29 00 HazardClass  6.1 PackingGroup  III Hazardous Substances Data 87-66-1(Hazardous Substances Data) Toxicity LD50 orally in rabbits: 1.6 g/kg (Dollahite) MSDS Information Provider Language SigmaAldrich English ACROS English ALFA English   Pyrogallol Usage And Synthesis Description Pyrogallol is a natural oxidant that can generate superoxide (O2-) in alkaline solutions through autoxidation to a semiquinone radical. Importantly, the semiquinone radical can react with O2- in an acidic environment to produce a quinone and H2O2. Pyrogallol autoxidation is used in superoxide dismutase activity assays. It can also be used in assays to assess antioxidant capacity. Pyrogallol is used in some biological systems as an O2- scavenger. In other biological systems, it is used as an O2- generator. Pyrogallol effectively scavenges DPPH radical (Item No. 14805) and ABTS+ in vitro. Pyrogallol is a product of tannin degradation to gallic acid (Item No. 11846) by ruminant microbes and has hepatotoxic and nephrotoxic effects in vivo. Chemical Properties White or nearly white needle- or leaf-shaped crystals or crystalline powder.Pyrogallol is practically odorless. Chemical Properties white crystalline solid Uses Pyrogallol possesses importance as a spectrophotometric reagent in the determination of niobium and tantalum. The absorptions of niobium and tantalum complexes are usually measured at 340 and 335 nm, respectively. The niobium complex is formed in slightly acidic medium, and the tantalum complex in strongly acidic medium (4 N HC1). The absorption spectra are pH-dependen. Uses Complexing agent; reducing agent; alkaline solution indicator for gaseous oxygen. Uses Pyrogallol is used in the manufacture of various dyes; in dyeing furs, hairs, and feathers; for staining leather; in engraving;as a developer in photography; and as an analytical reagent.. Production Methods Pyrogallol is prepared by heating dried gallic acid at about 200°C with the loss of carbon dioxide or by the chlorination of cyclohexanol to tetrachlorocyclohexanone, followed by hydrolysis. Definition ChEBI: A benzenetriol carrying hydroxy groups at positions 1, 2 and 3. General Description Odorless white to gray solid. Sinks and mixes with water. Air & Water Reactions Turns gray on exposure to light or air. Water soluble. Reactivity Profile Pyrogallol is a strong reducing agent. Reacts with alkalis, NH3, antipyrine, camphor, phenol, iron and lead salts, iodine, lime water, menthol and KMnO4. Hazard Toxic by ingestion and skin absorption. Health Hazard The toxic symptoms are similar to those of phenol. It can enter the body by absorption through skin and ingestion. The poisoning effects are nausea, vomiting, gastritis, hemolysis, methemoglobinemia, kidney and liver damage, convulsions, and congestion of lungs. High doses can cause death. Ingestion of 2–3 g of solid can be fatal to humans. The LD50 values varied widely in species. The oral LD50 value in mice is about 300 mg/kg. Health Hazard Inhalation of dust causes irritation of nose and throat. Ingestion may cause severe gastrointestinal irritation, convulsions, circulatory collapse, and death. Contact with eyes causes irritation. Skin contact can cause local discoloration, irritation, eczema, and death; repeated contact can cause sensitization. Fire Hazard Pyrogallol is probably combustible. Contact allergens Pyrogallol belongs to the phenols group. It is an old photograph developer and a low sensitizer in hair dyes. Biochem/physiol Actions Pyrogallol also referred to as 1,2,3-trihydroxybenzene inhibits the response to nitric oxide (NO) in the rat anococcygeus muscle. Safety Profile Human poison by ingestion and subcutaneous routes. An experimental poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. 1 198 PPRSOO PYROSULFURYL CHLORIDE Readdy absorbed through the skin. Human systemic effects by ingestion: convulsions, dyspnea, gastrointestinal effects. A severe skin and eye irritant. Incompatible with alkalies, NH3, antipyrine, phenol, iron and lead salts, iodine, KMn04. When heated to decomposition it emits acrid smoke and irritating fumes. Used as a topical antibacterial agent, as an intermediate, hair dye component, and analytical reagent. Carcinogenicity Pyrogallol was not carcinogenic in mouse and rabbit chronic dermal studies. Mice were treated twice weekly with pyrogallol in acetone (50%) on the shaved flank for life. There was no increase in dermal or systemic tumors. A similar study in rabbits also revealed no skin tumors, although positive controls showed an increase in tumors in both mice and rabbits. Pyrogallol was considered to be cocarcinogenic when administered dermally three times a week together with the skin carcinogen benzo[a]pyrene for 440 days; pyrogallol administered alone caused no increase in skin tumors.   Pyrogallol Preparation Products And Raw materials Preparation Products Atracurium besylate-->1,2,3-Trimethoxybenzene-->Ubidecarenone-->1,4-BUTANEDIOL DIACRYLATE-->4-Hydroxybutyl acrylate-->7,8-DIHYDROXY-4-METHYLCOUMARIN-->Exifone-->BENDIOCARB-->1-CHLOROMETHYL-2,3,4-TRIMETHOXYBENZENE-->Gallamine triethiodide-->1,3-Benzenediol, 2,5-dimethoxy--->GALLEIN-->7,8-Dihydroxyflavone-->7,8-Dihydroxycoumarin-->2'-HYDROXY-3',4'-DIMETHOXYACETOPHENONE-->5-TERT-BUTYLPYROGALLOL-->C.I.Mordant Green 22-->GALLEIN