China Largest Manufacturer factory sales POTASSIUM ALGINATE CAS 9005-36-1 CAS NO.9005-36-1

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POTASSIUM ALGINATE Basic information Product Name: POTASSIUM ALGINATE Synonyms: kelmar;kelmarimproved;potassiumpolymannuronate;KF 200S;Kimica Algin K;Kimica Algin K 3;Kimitsu Algin K;Potassium polyalginate CAS: 9005-36-1 MF: C12H16K2O13 MW: 446.44424 EINECS:   Product Categories: VX:15689727968 Mol File: 9005-36-1.mol   POTASSIUM ALGINATE Chemical Properties solubility  Potassium alginate is soluble in water, dissolving to form a viscous hydrophilic colloidal solution. It is insoluble in ethanol (95%) and in hydroalcoholic solutions in which the alcohol content is greater than 30% by weight; also insoluble in chloroform, ether, and acids having a pH lower than about 3. When preparing solutions of potassium alginate it is important to ensure proper dispersion of the particles, as poor dispersion will lead to the formation of large lumps of unhydrated powder and significantly extended hydration times. EPA Substance Registry System Alginic acid, potassium salt (9005-36-1)   Safety Information HS Code  3913100000 Hazardous Substances Data 9005-36-1(Hazardous Substances Data) MSDS Information   POTASSIUM ALGINATE Usage And Synthesis Chemical Properties Occurs in filamentous, grainy, granular, and powdered forms. It is colorless or slightly yel- low and may have a slight characteristic smell and taste. Slowly soluble in water, forming a viscous solution; insoluble in alcohol. Chemical Properties Potassium alginate occurs as a white to yellowish, fibrous or granular powder; it is almost odorless and tasteless. Uses Potassium Alginate is a gum that is the potassium salt of alginic acid. It is soluble in cold water, forming a viscous colloidal solution. It functions as a stabilizer, thickener, and gelling agent. It is used in dietetic foods, low-sodium foods, dry mixes, and dental impression material. Typical usage levels range from 0.05 to 0.50%. Uses Thickening agent and stabilizer in dairy prod- ucts, canned fruits, and sausage casings; emulsifier. See alginic acid. Definition Hydrophilic colloid having a molecular weight of 32,000–250,000. Production Methods Alginate obtained from brown seaweed is subjected to demineralization, extraction, and precipitation of alginic acid. Following neutralization, the potassium alginate obtained is dried and milled. Pharmaceutical Applications Potassium alginate is widely used in foods as a stabilizer, thickener, and emulsifier; however, its use as a pharmaceutical excipient is currently limited to experimental hydrogel systems. The viscosity, adhesiveness, elasticity, stiffness, and cohesiveness of potassium alginate hydrogels have been determined and compared with values from a range of other hydrogel-forming materials.The effect of calcium ions on the rheological properties of procyanidin hydrogels containing potassium alginate and intended for oral administration has also been investigated. Safety Potassium alginate is widely used in food products. It is currently used as an excipient only in experimental pharmaceutical formulations. storage In the solid state, potassium alginate is a stable material that is not prone to microbial spoilage. Over time, a slow reduction in the degree of polymerization can occur, which may be reflected in a reduction in the viscosity of solutions. As both temperature and moisture can impair the performance of potassium alginate, storage below 25°C is recommended. Potassium alginate solutions are stable at pH 4–10; long-term storage outside this range can result in depolymerization of the polymer through hydrolysis. Gelation or precipitation of the alginate can occur at pH values less than 4. Liquid or semisolid alginate formulations should be preserved: suitable preservatives are sodium benzoate, potassium sorbate, or parabens. Potassium alginate should be stored under cool, dry conditions in a well-closed container. Incompatibilities Incompatible with strong oxidizers. Regulatory Status GRAS listed. Accepted for use in foods in the USA and Europe.   POTASSIUM ALGINATE Preparation Products And Raw materials Raw materials Potassium hydroxide solution-->Sodium alginate   Product Name: 3-Hydroxybutyric acid Synonyms: RARECHEM AL BO 1231;(+/-)-3-HYDROXYBUTANOIC ACID;(+/-)-3-HYDROXYBUTYRIC ACID;3-HYDROXYBUTYRIC ACID;DL-3-HYDROXY-N-BUTYRIC ACID;DL-BETA-HYDROXYBUTYRIC ACID;BETA-HYDROXY-N-BUTYRIC ACID;dl-3-hydroxybutyric acid CAS: 625-71-8 MF: C4H8O3 MW: 104.1 EINECS: 206-099-9 Product Categories:   Mol File: 625-71-8.mol   3-Hydroxybutyric acid Chemical Properties Melting point  49°C Boiling point  118-120 °C/2 mmHg (lit.) density  1.126 g/mL at 25 °C (lit.) refractive index  n20/D 1.443(lit.) Fp  >230 °F storage temp.  2-8°C pka 4.70(at 25℃) CAS DataBase Reference 625-71-8(CAS DataBase Reference) EPA Substance Registry System Butanoic acid, 3-hydroxy-(625-71-8)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  26-36 WGK Germany  3 F  10 MSDS Information Provider Language 3-Hydroxybutanoic acid English SigmaAldrich English ACROS English ALFA English   3-Hydroxybutyric acid Usage And Synthesis Description In human, 3-hydroxylbutyric acid (ß-Hydroxybutyric acid or 3-hydrobutanoic acid) is one of the two primary endogenous agonists of hydroxycarboxylic acid receptor 2 (HCA2), a Gi/o-coupled G protein-coupled receptor (GPCR).1 It can be used for synthesis of biodegradable polymer, polyhydroxybutyrate.2 Reference H. Traussnig, E. Kloimstein, Extraktionsmittel für Poly-D(-)-3-hydroxybuttersäure, Patent EP0355307A2 Uses 3-Hydroxybutyric acid was used in enantioselective synthesis of D-(-)-3-hydroxybutyric acid by Escherichia coli. General Description 3-Hydroxybutyric acid forms films of random copolymer with (R)-3-hydroxypentanoic acid, (R)-3-hydroxyhexanoic acid, 4-hydroxybutyric acid, 6-hydroxyhexanoic acid and (S,S)-lactide by the melt-crystallized method. It is an important intermediate for the fine chemical industry.   3-Hydroxybutyric acid Preparation Products And Raw materials

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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POTASSIUM ALGINATE Basic information Product Name: POTASSIUM ALGINATE Synonyms: kelmar;kelmarimproved;potassiumpolymannuronate;KF 200S;Kimica Algin K;Kimica Algin K 3;Kimitsu Algin K;Potassium polyalginate CAS: 9005-36-1 MF: C12H16K2O13 MW: 446.44424 EINECS:   Product Categories: VX:15689727968 Mol File: 9005-36-1.mol   POTASSIUM ALGINATE Chemical Properties solubility  Potassium alginate is soluble in water, dissolving to form a viscous hydrophilic colloidal solution. It is insoluble in ethanol (95%) and in hydroalcoholic solutions in which the alcohol content is greater than 30% by weight; also insoluble in chloroform, ether, and acids having a pH lower than about 3. When preparing solutions of potassium alginate it is important to ensure proper dispersion of the particles, as poor dispersion will lead to the formation of large lumps of unhydrated powder and significantly extended hydration times. EPA Substance Registry System Alginic acid, potassium salt (9005-36-1)   Safety Information HS Code  3913100000 Hazardous Substances Data 9005-36-1(Hazardous Substances Data) MSDS Information   POTASSIUM ALGINATE Usage And Synthesis Chemical Properties Occurs in filamentous, grainy, granular, and powdered forms. It is colorless or slightly yel- low and may have a slight characteristic smell and taste. Slowly soluble in water, forming a viscous solution; insoluble in alcohol. Chemical Properties Potassium alginate occurs as a white to yellowish, fibrous or granular powder; it is almost odorless and tasteless. Uses Potassium Alginate is a gum that is the potassium salt of alginic acid. It is soluble in cold water, forming a viscous colloidal solution. It functions as a stabilizer, thickener, and gelling agent. It is used in dietetic foods, low-sodium foods, dry mixes, and dental impression material. Typical usage levels range from 0.05 to 0.50%. Uses Thickening agent and stabilizer in dairy prod- ucts, canned fruits, and sausage casings; emulsifier. See alginic acid. Definition Hydrophilic colloid having a molecular weight of 32,000–250,000. Production Methods Alginate obtained from brown seaweed is subjected to demineralization, extraction, and precipitation of alginic acid. Following neutralization, the potassium alginate obtained is dried and milled. Pharmaceutical Applications Potassium alginate is widely used in foods as a stabilizer, thickener, and emulsifier; however, its use as a pharmaceutical excipient is currently limited to experimental hydrogel systems. The viscosity, adhesiveness, elasticity, stiffness, and cohesiveness of potassium alginate hydrogels have been determined and compared with values from a range of other hydrogel-forming materials.The effect of calcium ions on the rheological properties of procyanidin hydrogels containing potassium alginate and intended for oral administration has also been investigated. Safety Potassium alginate is widely used in food products. It is currently used as an excipient only in experimental pharmaceutical formulations. storage In the solid state, potassium alginate is a stable material that is not prone to microbial spoilage. Over time, a slow reduction in the degree of polymerization can occur, which may be reflected in a reduction in the viscosity of solutions. As both temperature and moisture can impair the performance of potassium alginate, storage below 25°C is recommended. Potassium alginate solutions are stable at pH 4–10; long-term storage outside this range can result in depolymerization of the polymer through hydrolysis. Gelation or precipitation of the alginate can occur at pH values less than 4. Liquid or semisolid alginate formulations should be preserved: suitable preservatives are sodium benzoate, potassium sorbate, or parabens. Potassium alginate should be stored under cool, dry conditions in a well-closed container. Incompatibilities Incompatible with strong oxidizers. Regulatory Status GRAS listed. Accepted for use in foods in the USA and Europe.   POTASSIUM ALGINATE Preparation Products And Raw materials Raw materials Potassium hydroxide solution-->Sodium alginate   Product Name: 3-Hydroxybutyric acid Synonyms: RARECHEM AL BO 1231;(+/-)-3-HYDROXYBUTANOIC ACID;(+/-)-3-HYDROXYBUTYRIC ACID;3-HYDROXYBUTYRIC ACID;DL-3-HYDROXY-N-BUTYRIC ACID;DL-BETA-HYDROXYBUTYRIC ACID;BETA-HYDROXY-N-BUTYRIC ACID;dl-3-hydroxybutyric acid CAS: 625-71-8 MF: C4H8O3 MW: 104.1 EINECS: 206-099-9 Product Categories:   Mol File: 625-71-8.mol   3-Hydroxybutyric acid Chemical Properties Melting point  49°C Boiling point  118-120 °C/2 mmHg (lit.) density  1.126 g/mL at 25 °C (lit.) refractive index  n20/D 1.443(lit.) Fp  >230 °F storage temp.  2-8°C pka 4.70(at 25℃) CAS DataBase Reference 625-71-8(CAS DataBase Reference) EPA Substance Registry System Butanoic acid, 3-hydroxy-(625-71-8)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  26-36 WGK Germany  3 F  10 MSDS Information Provider Language 3-Hydroxybutanoic acid English SigmaAldrich English ACROS English ALFA English   3-Hydroxybutyric acid Usage And Synthesis Description In human, 3-hydroxylbutyric acid (ß-Hydroxybutyric acid or 3-hydrobutanoic acid) is one of the two primary endogenous agonists of hydroxycarboxylic acid receptor 2 (HCA2), a Gi/o-coupled G protein-coupled receptor (GPCR).1 It can be used for synthesis of biodegradable polymer, polyhydroxybutyrate.2 Reference H. Traussnig, E. Kloimstein, Extraktionsmittel für Poly-D(-)-3-hydroxybuttersäure, Patent EP0355307A2 Uses 3-Hydroxybutyric acid was used in enantioselective synthesis of D-(-)-3-hydroxybutyric acid by Escherichia coli. General Description 3-Hydroxybutyric acid forms films of random copolymer with (R)-3-hydroxypentanoic acid, (R)-3-hydroxyhexanoic acid, 4-hydroxybutyric acid, 6-hydroxyhexanoic acid and (S,S)-lactide by the melt-crystallized method. It is an important intermediate for the fine chemical industry.   3-Hydroxybutyric acid Preparation Products And Raw materials Product Name: Indole-6-carboxylic acid Synonyms: 6-INDOLECARBOXYLIC ACID;Indole-6-carboxylic acid in stock Factory;6-CARBOXYINDOLE;4-CARBOXAMIDOBENZOIC ACID;1H-INDOLE-6-CARBOXYLIC ACID;LABOTEST-BB LT00441293;INDOLE-6-CARBOXYLIC ACID;RARECHEM AL BE 1265 CAS: 1670-82-2 MF: C9H7NO2 MW: 161.16 EINECS: 605-464-3 Product Categories: Heterocycle-Indole series;Heterocyclic Building Blocks;Simple Indoles;Building Blocks;C7 to C9;Chemical Synthesis;blocks;Carboxes;IndolesOxindoles;Indole;Carboxylic Acids;Pyrroles & Indoles;Building Blocks;Heterocyclic Building Blocks;Indole/indoline/oxindole;Indole and Indoline;Indoles and derivatives;Carboxylic Acids;Pyrroles & Indoles;Organic acids;Indoles Mol File: 1670-82-2.mol   Indole-6-carboxylic acid Chemical Properties Melting point  249-253 °C(lit.) Boiling point  287.44°C (rough estimate) density  1.2480 (rough estimate) refractive index  1.5050 (estimate) storage temp.  Keep in dark place,Sealed in dry,Room Temperature pka 4.44±0.30(Predicted) form  Powder color  Yellow-beige to orange-brown BRN  123991 CAS DataBase Reference 1670-82-2(CAS DataBase Reference)   Safety Information Hazard Codes  Xn,Xi Risk Statements  36/37/38-21/22-20/21/22-51-36-22 Safety Statements  22-24/25-37/39-26 WGK Germany  3 Hazard Note  Irritant HS Code  29339900 MSDS Information Provider Language SigmaAldrich English ACROS English ALFA English   Indole-6-carboxylic acid Usage And Synthesis Chemical Properties yellow-beige to orange-brown powder Uses • ;Reactant for preparation of D-glutamic acid-based inhibitors of E. coli MurD ligase1• ;Reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors2• ;Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway3• ;Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity4• ;Reactant for preparation of pyridinyl carboxylates via esterification with chlorohyd Uses Reactant for preparation of D-glutamic acid-based inhibitors of E. coli MurD ligase Reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors Reactant for preparation of amide conju Uses Reactant for preparation of D-glutamic acid-based inhibitors of E. coli MurD ligase Reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity Reactant for preparation of pyridinyl carboxylates via esterification with chlorohydroxypyridine as SARS-CoV 3CL proinhibitors Reactant for preparation of (indolecarbonyl)-D-phenylglycinamide amides as factor Xa inhibitors Synthesis Reference(s) Journal of Medicinal Chemistry, 35, p. 2419, 1992 DOI: 10.1021/jm00091a010   Indole-6-carboxylic acid Preparation Products And Raw materials Raw materials Sodium hydroxide-->Hydrochloric acid-->Methanol-->Tetrahydrofuran-->N,N-Dimethylformamide-->Palladium-->N,N-Dimethylformamide dimethyl acetal-->Pyrrolidine-->4-Methyl-3-nitrobenzoic acid Preparation Products AKOS B006681