The world Biggest Manufacturer factory sales Cinnamaldehyde CAS 104-55-2 CAS NO.104-55-2

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Cinnamaldehyde Basic information Product Name: Cinnamaldehyde Synonyms: 3-PHENYLPROPENAL;AKOS B004060;AKOS BBS-00003207;CINNAMIC ALDEHYDE;CINNAMALDEHYDE;CINNAMALDEHYDE, TRANS-;LABOTEST-BB LT00939010;FEMA 2286 CAS: 104-55-2 MF: C9H8O MW: 132.16 EINECS: 203-213-9 Product Categories: chemical reagent;pharmaceutical intermediate;Aromatic Aldehydes & Derivatives (substituted);phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Pharmaceutical Intermediates;Alphabetical Listings;C-DFlavors and Fragrances;Certified Natural Products;Flavors and Fragrances;Cosmetics;104-55-2 Mol File: 104-55-2.mol   Cinnamaldehyde Chemical Properties Melting point  −9-−4 °C(lit.) Boiling point  248 °C (lit.) density  1.05 g/mL at 25 °C (lit.) vapor density  4.6 (vs air) vapor pressure  <0.1 hPa (20 °C) FEMA  2286 | CINNAMALDEHYDE refractive index  n20/D 1.622(lit.) Fp  160 °F storage temp.  Store below +30°C. solubility  1g/l soluble form  Liquid Specific Gravity 1.05 color  Clear yellow Odor Strong odor of cinnamon Water Solubility  Slightly soluble JECFA Number 656 Merck  13,2319 Stability: Stable. Combustible. Incompatible with strong oxidizing agents, strong bases. InChIKey KJPRLNWUNMBNBZ-QPJJXVBHSA-N CAS DataBase Reference 104-55-2(CAS DataBase Reference) NIST Chemistry Reference Cinnamylaldehyde(104-55-2) EPA Substance Registry System Cinnamaldehyde (104-55-2)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38-43 Safety Statements  26-36/37 RIDADR  UN8027 WGK Germany  3 RTECS  GD6476000 F  10-23 HS Code  29122900 Hazardous Substances Data 104-55-2(Hazardous Substances Data) Toxicity LD50 in rats (mg/kg): 2220 orally (Jenner) MSDS Information Provider Language Cinnamaldehyde English ACROS English SigmaAldrich English ALFA English   Cinnamaldehyde Usage And Synthesis Description Cinnamic aldehyde is used as a flavoring agent, ingredient of fragrance in soft drinks, ice creams, dentifrices, pastries, chewing-gum, etc. It can induce both contact urticaria and delayed-type reactions. It can be implicated in contact dermatitis in those who work in the perfume industry or food handlers. Cinnamic aldehyde is contained in the "fragrance mix". Chemical Properties Cinnamaldehyde exists as yellowish to greenish-yellow oily liquid with a Strong pungent, spicy, cinnamon odor. It is normally insoluble in water and many organic solvents but is miscible with alcohol and other flavoring oils. Exposure to air will result in thickening and oxidation. Cinnamaldehyde (cinnamic aldehyde, benzylideneactaldehyde, phenylacrolein, 3-phenylpropenal, 3-phenyl-2-propenal) is a saturated aldehyde with an aromatic ring that is a yellowish, oily liquid at room temperature. It is used as a flavoring and aromatic agent in a variety of food products, perfumes, and household products. It has also seen use as a rubber reinforcing agent. A burning taste that produces the odor and flavor of the spice may be found with this aromatic aldehyde. Cinnamaldehyde has also been used as an attractant for insect control, in the preparation of corrosion inhibitors, and as a coating for metals. Although extensively used in industry, it is also a natural constituent of cinnamon leaves and bark, some essential oils, and other plant products. Occurrence Reported found in celery seed, cinnamon, cinnamon leaf, cassia leaf, clove stem and lemon balm. Uses Cinnamaldehyde is used in flavor and perfumes.It occurs in cinnamon oils. Uses In the flavor and perfume industry. Uses Cinnamic aldehyde is a common ingredient in perfumes for household products like deodorizers, detergents, and soap; flavor in toothpaste, sweets, ice cream, soft drinks, chewing gums, and cakes; in balsam of Tolu and Peru, hyacinth plant, spices, cinnamon, Ceylon and cassia oil; some perfumery uses (Canoe; hyacinth; bubblegum; Balsam; Cassia); natural occurrence (cinnamon). Aroma threshold values Detection at 50 to 750 ppb. Taste threshold values Taste characteristics at 0.5 ppm: spicy, cinnamon and cinnamon bark. General Description Yellow oily liquid with a cinnamon odor and sweet taste. Air & Water Reactions Thickens on exposure to air. May be unstable to prolonged exposure to air. Slightly water soluble . Reactivity Profile Cinnamaldehyde reacts with sodium hydroxide owing to aerobic oxidation. Health Hazard Cinnamaldehyde can cause moderate to severeskin irritation. Exposure to 40 mg in48 hours produced a severe irritation effecton human skin. The toxicity of this compoundwas low to moderate on test subjects,depending on the species and the toxicroutes. However, when given by oral routein large amounts, its poisoning effect wassevere. Amounts greater than 1500 mg/kghave produced a wide range of toxic effectsin rats, mice, and guinea pigs. The symptomswere respiratory stimulation, somnolence,convulsion, ataxia, coma, hypermotility, anddiarrhea. LD50 value, oral (guinea pigs): 1150 mg/kg Cinnamaldehyde is a mutagen. Its carcinogeniceffect is not established. Fire Hazard Cinnamaldehyde is combustible. Agricultural Uses Fungicide, Insecticide: Used as an antifungal agent, corn rootworm attractant, and dog and cat repellent. Can be used on soil casing for mushrooms, row crops, turf and all food commodities. Not listed for use in EU countries. Trade name ADIOS®; ZIMTALDEHYDE®; ZIMTALDEHYDE® LIGHT Contact allergens This perfumed molecule is used as a fragrance in perfumes, a flavoring agent in soft drinks, ice creams, dentifrices, pastries, chewing-gum, etc. It can induce both contact urticaria and delayed-type reactions. It can be responsible for dermatitis in the perfume industry or in food handlers. Cinnamic aldehyde is contained in “fragrance mix.” As a fragrance allergen, it has to be mentioned by name in cosmetics within the EU. Anticancer Research This is promising in antitumor activity against NSCLC cells. The cells were inducedin apoptosis and also the epithelial-mesenchymal transition was reversed affectingthe Wnt/b-catenin pathway (Bouyahya et al. 2016). Safety Profile Poison by intravenous and parenteral routes. Moderately toxic by ingestion and intraperitoneal routes. A severe human skin irritant. Mutation data reported. Combustible liquid. May ipte after a delay period in contact with NaOH. When heated to decomposition it emits acrid smoke and fumes. See also ALDEHYDES. Chemical Synthesis By isolation from natural sources; synthetically, by condensation of benzaldehyde with acetaldehyde in the presence of sodium or calcium hydroxide. Potential Exposure Botanical fungicide and insecticide. Used as an antifungal agent, corn rootworm attractant, and dog and cat repellent. Can be used on soil casing for mushrooms, row crops, turf, and all food commodities. Not listed for use in EU countries. Shipping UN1989 Aldehydes, n.o.s., Hazard Class: 3; Labels: 3-Flammable liquid Incompatibilities Aldehydes are frequently involved in selfcondensation or polymerization reactions. These reactions are exothermic; they are often catalyzed by acid. Aldehydes are readily oxidized to give carboxylic acids. Flammable and/or toxic gases are generated by the combination of aldehydes with azo, diazo compounds, dithiocarbamates, nitrides, and strong reducing agents. Aldehydes can react with air to give first peroxo acids, and ultimately carboxylic acids. These autoxidation reactions are activated by light, catalyzed by salts of transition metals, and are autocatalytic (catalyzed by the products of the reaction). The addition of stabilizers (antioxidants) to shipments of aldehydes retards autoxidation. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, ketones, azo dyes, caustics, boranes, hydrazines Waste Disposal Incineration. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers.   Cinnamaldehyde Preparation Products And Raw materials Raw materials Benzaldehyde-->Sulfurous Acid-->trans-Cinnamaldehyde-->Cinnamon oil Preparation Products Cinnamyl alcohol-->trans-Cinnamaldehyde-->Epalrestat-->α-Bromocinnamaldehyde-->Toremifene-->1,4-DIPHENYLBUTADIYNE-->1-Hydroxy-3-phenyl-1,3-propanedisulfonic acid disodium salt-->METHYL BIPHENYL-2-CARBOXYLATE-->Cyclohexanepropionic acid-->4,6-DIPHENYL-2-PYRONE-->CINNAMONITRILE-->CINNAMALDEHYDE DIETHYL ACETAL

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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Cinnamaldehyde Basic information Product Name: Cinnamaldehyde Synonyms: 3-PHENYLPROPENAL;AKOS B004060;AKOS BBS-00003207;CINNAMIC ALDEHYDE;CINNAMALDEHYDE;CINNAMALDEHYDE, TRANS-;LABOTEST-BB LT00939010;FEMA 2286 CAS: 104-55-2 MF: C9H8O MW: 132.16 EINECS: 203-213-9 Product Categories: chemical reagent;pharmaceutical intermediate;Aromatic Aldehydes & Derivatives (substituted);phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Pharmaceutical Intermediates;Alphabetical Listings;C-DFlavors and Fragrances;Certified Natural Products;Flavors and Fragrances;Cosmetics;104-55-2 Mol File: 104-55-2.mol   Cinnamaldehyde Chemical Properties Melting point  −9-−4 °C(lit.) Boiling point  248 °C (lit.) density  1.05 g/mL at 25 °C (lit.) vapor density  4.6 (vs air) vapor pressure  <0.1 hPa (20 °C) FEMA  2286 | CINNAMALDEHYDE refractive index  n20/D 1.622(lit.) Fp  160 °F storage temp.  Store below +30°C. solubility  1g/l soluble form  Liquid Specific Gravity 1.05 color  Clear yellow Odor Strong odor of cinnamon Water Solubility  Slightly soluble JECFA Number 656 Merck  13,2319 Stability: Stable. Combustible. Incompatible with strong oxidizing agents, strong bases. InChIKey KJPRLNWUNMBNBZ-QPJJXVBHSA-N CAS DataBase Reference 104-55-2(CAS DataBase Reference) NIST Chemistry Reference Cinnamylaldehyde(104-55-2) EPA Substance Registry System Cinnamaldehyde (104-55-2)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38-43 Safety Statements  26-36/37 RIDADR  UN8027 WGK Germany  3 RTECS  GD6476000 F  10-23 HS Code  29122900 Hazardous Substances Data 104-55-2(Hazardous Substances Data) Toxicity LD50 in rats (mg/kg): 2220 orally (Jenner) MSDS Information Provider Language Cinnamaldehyde English ACROS English SigmaAldrich English ALFA English   Cinnamaldehyde Usage And Synthesis Description Cinnamic aldehyde is used as a flavoring agent, ingredient of fragrance in soft drinks, ice creams, dentifrices, pastries, chewing-gum, etc. It can induce both contact urticaria and delayed-type reactions. It can be implicated in contact dermatitis in those who work in the perfume industry or food handlers. Cinnamic aldehyde is contained in the "fragrance mix". Chemical Properties Cinnamaldehyde exists as yellowish to greenish-yellow oily liquid with a Strong pungent, spicy, cinnamon odor. It is normally insoluble in water and many organic solvents but is miscible with alcohol and other flavoring oils. Exposure to air will result in thickening and oxidation. Cinnamaldehyde (cinnamic aldehyde, benzylideneactaldehyde, phenylacrolein, 3-phenylpropenal, 3-phenyl-2-propenal) is a saturated aldehyde with an aromatic ring that is a yellowish, oily liquid at room temperature. It is used as a flavoring and aromatic agent in a variety of food products, perfumes, and household products. It has also seen use as a rubber reinforcing agent. A burning taste that produces the odor and flavor of the spice may be found with this aromatic aldehyde. Cinnamaldehyde has also been used as an attractant for insect control, in the preparation of corrosion inhibitors, and as a coating for metals. Although extensively used in industry, it is also a natural constituent of cinnamon leaves and bark, some essential oils, and other plant products. Occurrence Reported found in celery seed, cinnamon, cinnamon leaf, cassia leaf, clove stem and lemon balm. Uses Cinnamaldehyde is used in flavor and perfumes.It occurs in cinnamon oils. Uses In the flavor and perfume industry. Uses Cinnamic aldehyde is a common ingredient in perfumes for household products like deodorizers, detergents, and soap; flavor in toothpaste, sweets, ice cream, soft drinks, chewing gums, and cakes; in balsam of Tolu and Peru, hyacinth plant, spices, cinnamon, Ceylon and cassia oil; some perfumery uses (Canoe; hyacinth; bubblegum; Balsam; Cassia); natural occurrence (cinnamon). Aroma threshold values Detection at 50 to 750 ppb. Taste threshold values Taste characteristics at 0.5 ppm: spicy, cinnamon and cinnamon bark. General Description Yellow oily liquid with a cinnamon odor and sweet taste. Air & Water Reactions Thickens on exposure to air. May be unstable to prolonged exposure to air. Slightly water soluble . Reactivity Profile Cinnamaldehyde reacts with sodium hydroxide owing to aerobic oxidation. Health Hazard Cinnamaldehyde can cause moderate to severeskin irritation. Exposure to 40 mg in48 hours produced a severe irritation effecton human skin. The toxicity of this compoundwas low to moderate on test subjects,depending on the species and the toxicroutes. However, when given by oral routein large amounts, its poisoning effect wassevere. Amounts greater than 1500 mg/kghave produced a wide range of toxic effectsin rats, mice, and guinea pigs. The symptomswere respiratory stimulation, somnolence,convulsion, ataxia, coma, hypermotility, anddiarrhea. LD50 value, oral (guinea pigs): 1150 mg/kg Cinnamaldehyde is a mutagen. Its carcinogeniceffect is not established. Fire Hazard Cinnamaldehyde is combustible. Agricultural Uses Fungicide, Insecticide: Used as an antifungal agent, corn rootworm attractant, and dog and cat repellent. Can be used on soil casing for mushrooms, row crops, turf and all food commodities. Not listed for use in EU countries. Trade name ADIOS®; ZIMTALDEHYDE®; ZIMTALDEHYDE® LIGHT Contact allergens This perfumed molecule is used as a fragrance in perfumes, a flavoring agent in soft drinks, ice creams, dentifrices, pastries, chewing-gum, etc. It can induce both contact urticaria and delayed-type reactions. It can be responsible for dermatitis in the perfume industry or in food handlers. Cinnamic aldehyde is contained in “fragrance mix.” As a fragrance allergen, it has to be mentioned by name in cosmetics within the EU. Anticancer Research This is promising in antitumor activity against NSCLC cells. The cells were inducedin apoptosis and also the epithelial-mesenchymal transition was reversed affectingthe Wnt/b-catenin pathway (Bouyahya et al. 2016). Safety Profile Poison by intravenous and parenteral routes. Moderately toxic by ingestion and intraperitoneal routes. A severe human skin irritant. Mutation data reported. Combustible liquid. May ipte after a delay period in contact with NaOH. When heated to decomposition it emits acrid smoke and fumes. See also ALDEHYDES. Chemical Synthesis By isolation from natural sources; synthetically, by condensation of benzaldehyde with acetaldehyde in the presence of sodium or calcium hydroxide. Potential Exposure Botanical fungicide and insecticide. Used as an antifungal agent, corn rootworm attractant, and dog and cat repellent. Can be used on soil casing for mushrooms, row crops, turf, and all food commodities. Not listed for use in EU countries. Shipping UN1989 Aldehydes, n.o.s., Hazard Class: 3; Labels: 3-Flammable liquid Incompatibilities Aldehydes are frequently involved in selfcondensation or polymerization reactions. These reactions are exothermic; they are often catalyzed by acid. Aldehydes are readily oxidized to give carboxylic acids. Flammable and/or toxic gases are generated by the combination of aldehydes with azo, diazo compounds, dithiocarbamates, nitrides, and strong reducing agents. Aldehydes can react with air to give first peroxo acids, and ultimately carboxylic acids. These autoxidation reactions are activated by light, catalyzed by salts of transition metals, and are autocatalytic (catalyzed by the products of the reaction). The addition of stabilizers (antioxidants) to shipments of aldehydes retards autoxidation. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, ketones, azo dyes, caustics, boranes, hydrazines Waste Disposal Incineration. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers.   Cinnamaldehyde Preparation Products And Raw materials Raw materials Benzaldehyde-->Sulfurous Acid-->trans-Cinnamaldehyde-->Cinnamon oil Preparation Products Cinnamyl alcohol-->trans-Cinnamaldehyde-->Epalrestat-->α-Bromocinnamaldehyde-->Toremifene-->1,4-DIPHENYLBUTADIYNE-->1-Hydroxy-3-phenyl-1,3-propanedisulfonic acid disodium salt-->METHYL BIPHENYL-2-CARBOXYLATE-->Cyclohexanepropionic acid-->4,6-DIPHENYL-2-PYRONE-->CINNAMONITRILE-->CINNAMALDEHYDE DIETHYL ACETAL