China Largest Manufacturer factory sales Sulfogaiacol CAS 1321-14-8 CAS NO.1321-14-8

                                PRODUCT DETAILS       

Sulfogaiacol Basic information Product Name: Sulfogaiacol Synonyms: GUAIACOL SULFONIC ACID POTASSIUM;GUAIACOLSULFONIC ACID POTASSIUM SALT;4-HYDROXY-3-METHOXYBENZENESULFONIC ACID POTASSIUM SALT;sulfogaiacol;POTASSIUM GUAIACOLSULFONATE;potassium 2-(hydroxymethoxy)benzenesulfonate;potassium 4-hydroxy-3-methoxybenzenesulphonate--potassium 3-hydroxy-4-methoxybenzenesulphonate;Potassium guaiacol sulphonate CAS: 1321-14-8 MF: C7H7KO5S MW: 242.29 EINECS: 215-314-5 Product Categories: API;API's Mol File: 1321-14-8.mol   Sulfogaiacol Chemical Properties CAS DataBase Reference 1321-14-8(CAS DataBase Reference) EPA Substance Registry System Benzenesulfonic acid, hydroxymethoxy-, monopotassium salt (1321-14-8)   Safety Information WGK Germany  3 MSDS Information Provider Language SigmaAldrich English   Sulfogaiacol Usage And Synthesis Uses Expectorant.   Sulfogaiacol Preparation Products And Raw materials Raw materials Guaiacol

                                                              About US 
Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

                                                                       Group profiles

Our Factories production lines

                                                   Our Factories R&D ability

                        Our Factories warehouse 

                                                       Product information

UV Absorber 326 Basic information Characterization Physical Properties Features/Benefits Applications Guidelines for use Handling & Safety Product Name: UV Absorber 326 Synonyms: 2-T-BUTYL-6-(5-CHLORO-2 H-BENZOTRIAZOL-2-YL)-4-METHYLPHENOL;BUMETRIZOLE;LABOTEST-BB LT00138024;TINUVIN 326;ULTRA-VIOLET ABSORBER UV-326;ULTRAVIOLET ABSORBENT UV-326;2-(5-chloro-2h-benzotriazol-2-yl)-6-(1,1-dimethylethyl)-4-methyl-pheno;Phenol, 2-(5-chloro-2H-benzotriazol-2-yl)-6-(1,1-dimethylethyl)-4-methyl- CAS: 3896-11-5 MF: C17H18ClN3O MW: 315.8 EINECS: 223-445-4 Product Categories: Polymer Additives;Polymer Science;Industrial/Fine Chemicals;Polymer Additives;Polymer Science;Stabilizers Mol File: 3896-11-5.mol   UV Absorber 326 Chemical Properties Melting point  144-147 °C(lit.) Boiling point  460.4±55.0 °C(Predicted) density  1.26±0.1 g/cm3(Predicted) storage temp.  Sealed in dry,Room Temperature solubility  Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) pka 9.31±0.48(Predicted) form  Solid color  Pale Yellow to Light Yellow InChIKey OCWYEMOEOGEQAN-UHFFFAOYSA-N CAS DataBase Reference 3896-11-5(CAS DataBase Reference) EPA Substance Registry System 2-tert-Butyl-6-(5-chloro-2H-benzotriazol-2-yl)-p-cresol (3896-11-5)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38-53 Safety Statements  26-36-61 WGK Germany  1 HS Code  29339900 MSDS Information Provider Language SigmaAldrich English   UV Absorber 326 Usage And Synthesis Characterization UV Absorber 326 is a UV absorber of the hydroxyphenylbenzotriazole class, which imparts outstanding light stability to plastics and other organic substrates. Physical Properties Features/Benefits UV Absorber 326 has a wide range of indirect food approvals in polyolefins. It has a low volatility at high temperatures and high resistance to thermal degradation and can therefore be used without significant loss or decomposition in the polyolefin compounding and molding processes. In the use for the UV protection of polyester resins, TINUVIN 326 does not form colored complexes with the metallic salts used for the curing process of these resins. Applications UV Absorber 326 is especially suited for polyolefins and cold cured polyesters. Guidelines for use Handling & Safety In accordance with good industrial practice, handle with care and avoid unnecessary personal contact. Avoid continuous or repetitive breathing of dust. Use only with adequate ventilation. Prevent contamination of the environment. Avoid dust formation and ignition sources. For more detailed information please refer to the material safety data sheet. Chemical Properties Pale Yellow Solid Originator Bumetrizole,Onbio Inc. Uses Bumetrizole is an intermediate reactant in the synthesis of UV light absorbers for polyester fibers. Uses UV-326 can potentially be used as a UV light filter in cosmetics and sunscreens. It may also be used as a corrosion inhibitor for the protection of building materials and automobiles. Manufacturing Process To a 2000 ml 3-necked, round-bottomed flask equipped with an agitator, reflux condenser, nitrogen inlet and thermometer were charged 140.5 g of 2'- hydroxy-3'-t-butyl-5'-methyl-5-chloro-2-nitroazobenzene, 119 g of isopropanol and 80 g of Amsco mineral spirits. A stream of nitrogen was introduced over the surface of the contents of the flask and the nitrogen atmosphere was then maintained throughout the remainder of the reduction process. 13.7 g of 50% aqueous sodium hydroxide solution and 222 g of water were added and the temperature of the contents of the flask were adjusted to 55°C. The ratio of the moles of alkali to moles of o-nitroazobenzene intermediate used was is 0.848/1. 104 g of zinc dust was added in 5 portions over a 2 hours period with the temperature of the flask being held at 55-60°C with some slight external cooling. The total concentration of iron impurities from all reactants less than 150 ppm based on zinc used. After all the zinc was added, the temperature was raised to 60°C and held at this temperature until a spot test indicated no more o-nitroazobenzene intermediate was present. The temperature was then raised to 65°C and held there for 4 to 5 hours or until TLC analysis indicated that no more of the N-oxy-intermediate was present. 62.6 g of anhydrous sodium sulfate and 35.6 g of water were then added, the batch was heated to 70°C and stirred for 15 min. The material was then allowed to stand and separate into three liquid phases plus unreacted zinc dust. The top two layers containing the desired product were transferred to another flask. The remaining aqueous zinc slurry was washed at 65-70°C with three successive 16 g portions of Amsco mineral spirits: isopropanol 50:50. The combined product layers and wash liquids were then washed once at 70°C with an aqueous hydrochloric acid solution made from 130 g of water and 40 g of 32% hydrochloric acid to remove cleavage amine by-products. A second and third wash followed at 70°C with aqueous hydrochloric acid solutions made each from 65 g of water and 20 g of 32% hydrochloric acid. The last wash was essentially colorless. 14 g of 32% hydrochloric acid and 220 g of isopropanol were added to the solution of the product. The batch was allowed to crystallize slowly. The solid product form was filtered and washed with isopropanol at 0°C to give 110 g of 5-chloro-2-(2-hydroxy-3-t-butyl-5- methylphenyl)-2H-benzotriazole with a melting point of 140-141°C. Therapeutic Function Sunscreen agent General Description 2-tert-Butyl-6-(5-chloro-2H-benzotriazol-2-yl)-4-methylphenol (UV-326) is a benzotriazole based UV absorber that can be used in the photostabilization of industrial materials. It can absorb the harmful UV radiation for the wavelength of about 290 nm.   UV Absorber 326 Preparation Products And Raw materials Raw materials Sodium hydroxide-->Hydrochloric acid-->ZINC Preparation Products Deltamethrin