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Home > Products >  China Biggest Factory manufacturer supply Neohesperidin

China Biggest Factory manufacturer supply Neohesperidin CAS NO.13241-33-3

  • FOB Price: USD: 1.00-2.00 /Kilogram Get Latest Price
  • Min.Order: 500 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,MoneyGram,Other
  • Available Specifications:

    AAAAA(50-100)KilogramAAAAA(100-500)Kilogram

  • Product Details

Keywords

  • Neohesperidin
  • Neohesperidin
  • 13241-33-3

Quick Details

  • ProName: China Biggest Factory manufacturer sup...
  • CasNo: 13241-33-3
  • Molecular Formula: 13241-33-3
  • Appearance: white powder
  • Application: Pharm chemicals industry
  • DeliveryTime: 3-5 days
  • PackAge: 25KG/Drum
  • Port: Shanghai Guangzhou Qingdao Shenzhen
  • ProductionCapacity: 200 Metric Ton/Month
  • Purity: 99%
  • Storage: 2-8°C
  • Transportation: By air /Sea/ coruier
  • LimitNum: 500 Kilogram
  • Ash Content: 10
  • Heavy Metal: 10
  • Voluntary Standards: QS
  • Valid Period: 2
  • Color: white
  • Melting point: ≥350°C
  • Boiling point: 363.24°C (rough estimate)
  • density: 1.667
  • solubility: 1 M NaOH: 10 mg/mL, dark green
  • Water Solubility: <0.1 g/100 mL at 21 oC
  • Stability: Stable. Combustible. Incompatible with...

Superiority

                                PRODUCT DETAILS                           

Neohesperidin Basic information
Product Name: Neohesperidin
Synonyms: HESPERETIN-7-NEOHESPERIDOSIDE;HESPERETIN-7-O-NEOHESPERIDOSIDE;Neohesperidin HPLC 96% Min;(s)-a-d-glucopyranosyl)oxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl);4h-1-benzopyran-4-one,2,3-dihydro-7-((2-o-(6-deoxy-alpha-l-mannopyranosyl)-bet;Neohesperidin≥ 98% (HPLC);7-[[4,5-dihydroxy-6-(hydroxymethyl)-3-[(3,4,5-trihydroxy-6-methyl-2-oxanyl)oxy]-2-oxanyl]oxy]-5-hydroxy-2-(3-hydroxy-5-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one;Neohesperidin 95% HPLC
CAS: 13241-33-3
MF: C28H34O15
MW: 610.56
EINECS: 236-216-9
Product Categories: CITRIMORE;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Flavanones;Inhibitors
Mol File: 13241-33-3.mol
Neohesperidin Structure
 
Neohesperidin Chemical Properties
Melting point  239-243°C
Boiling point  933.7±65.0 °C(Predicted)
density  1.65±0.1 g/cm3(Predicted)
storage temp.  Sealed in dry,2-8°C
solubility  DMSO (Slightly), Pyridine (Slightly)
pka 7.14±0.40(Predicted)
form  neat
color  White to Off-White
BRN  74945
InChIKey ARGKVCXINMKCAZ-RTFRIYMLSA-N
CAS DataBase Reference 13241-33-3(CAS DataBase Reference)
 
Safety Information
Safety Statements  22-24/25
WGK Germany  3
RTECS  DJ2981400
10-21
HS Code  29389090
MSDS Information
Provider Language
SigmaAldrich English
 
Neohesperidin Usage And Synthesis
Description Neohesperidin is a flavonoid found in citrus fruit peel that has diverse biological activities. In vitro, it inhibits osteoclast differentiation, bone resorption, calcium oscillations, and activation of NF-κB and nuclear factor of activated T cells (NFAT) by receptor activator of NF-κB ligand (RANKL). In vivo, neohesperidin administration protects ovariectomized mice from bone loss. Neohesperidin acts as a hypolipidemic agent, reducing lipid accumulation in HepG2 cells and reversing hyperlipidemia in a mouse model of diet-induced obesity. In a mouse model of diabetes, neohesperidin increases glucose tolerance and decreases insulin resistance while simultaneously decreasing serum triglycerides and total cholesterol and inhibiting lipid accumulation in livers in vivo.
Chemical Properties White powder
Uses Neohesperidin can be used in cosmetic products and as a sweetening agent in food & beverages, an antioxidant flavanone glycoside
Uses An antioxidant flavanone glycoside
Uses Neohesperidin exhibits lipid-regulating effects in vivo and in vitro. It is a main flavonoid in citrus byproducts (CBP) which possesses anti-oxidant activity.
Definition ChEBI: A flavanone glycoside that is hesperitin having an 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety attached to the 7-hydroxy group.
 
Neohesperidin Preparation Products And Raw materials
Preparation Products Neosperidin dihydrochalcone
.

 

                                Group profiles

Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

 

Our Factories production lines

                                                   Our Factories R&D ability

                        Our Factories warehouse 

                

Details

                                                       Product information

Neohesperidin Basic information
Product Name: Neohesperidin
Synonyms: HESPERETIN-7-NEOHESPERIDOSIDE;HESPERETIN-7-O-NEOHESPERIDOSIDE;Neohesperidin HPLC 96% Min;(s)-a-d-glucopyranosyl)oxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl);4h-1-benzopyran-4-one,2,3-dihydro-7-((2-o-(6-deoxy-alpha-l-mannopyranosyl)-bet;Neohesperidin≥ 98% (HPLC);7-[[4,5-dihydroxy-6-(hydroxymethyl)-3-[(3,4,5-trihydroxy-6-methyl-2-oxanyl)oxy]-2-oxanyl]oxy]-5-hydroxy-2-(3-hydroxy-5-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one;Neohesperidin 95% HPLC
CAS: 13241-33-3
MF: C28H34O15
MW: 610.56
EINECS: 236-216-9
Product Categories: CITRIMORE;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Flavanones;Inhibitors
Mol File: 13241-33-3.mol
Neohesperidin Structure
 
Neohesperidin Chemical Properties
Melting point  239-243°C
Boiling point  933.7±65.0 °C(Predicted)
density  1.65±0.1 g/cm3(Predicted)
storage temp.  Sealed in dry,2-8°C
solubility  DMSO (Slightly), Pyridine (Slightly)
pka 7.14±0.40(Predicted)
form  neat
color  White to Off-White
BRN  74945
InChIKey ARGKVCXINMKCAZ-RTFRIYMLSA-N
CAS DataBase Reference 13241-33-3(CAS DataBase Reference)
 
Safety Information
Safety Statements  22-24/25
WGK Germany  3
RTECS  DJ2981400
10-21
HS Code  29389090
MSDS Information
Provider Language
SigmaAldrich English
 
Neohesperidin Usage And Synthesis
Description Neohesperidin is a flavonoid found in citrus fruit peel that has diverse biological activities. In vitro, it inhibits osteoclast differentiation, bone resorption, calcium oscillations, and activation of NF-κB and nuclear factor of activated T cells (NFAT) by receptor activator of NF-κB ligand (RANKL). In vivo, neohesperidin administration protects ovariectomized mice from bone loss. Neohesperidin acts as a hypolipidemic agent, reducing lipid accumulation in HepG2 cells and reversing hyperlipidemia in a mouse model of diet-induced obesity. In a mouse model of diabetes, neohesperidin increases glucose tolerance and decreases insulin resistance while simultaneously decreasing serum triglycerides and total cholesterol and inhibiting lipid accumulation in livers in vivo.
Chemical Properties White powder
Uses Neohesperidin can be used in cosmetic products and as a sweetening agent in food & beverages, an antioxidant flavanone glycoside
Uses An antioxidant flavanone glycoside
Uses Neohesperidin exhibits lipid-regulating effects in vivo and in vitro. It is a main flavonoid in citrus byproducts (CBP) which possesses anti-oxidant activity.
Definition ChEBI: A flavanone glycoside that is hesperitin having an 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety attached to the 7-hydroxy group.
 
Neohesperidin Preparation Products And Raw materials
Preparation Products Neosperidin dihydrochalcone

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