China Biggest Factory manufacturer supply Sodium Ascorbate/SODIUM L-ASCORBATE CAS NO.134-03-2

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

Product information

Sodium ascorbate Basic information Description References Product Name: Sodium ascorbate Synonyms: ASCORBIC ACID SODIUM SALT;L(+)-ASCORBIC ACID SODIUM SALT;L-ASCORBIC ACID SODIUM SALT;L-ASCORBIC ACID NA-SALT;SODIUMASCORBATE,GRANULAR,FCC;SODIUMASCORBATE,GRANULAR,USP;SODIUMASCORBATE,POWDER,USP;SODIUM ASCORBATE (VC-NA) AND ITS DIRECTLY-COMPRESSION GRANULE CAS: 134-03-2 MF: C6H7NaO6 MW: 198.11 EINECS: 205-126-1 Product Categories: Vitamins and derivatives;Antioxidant;Biochemistry;Sugar Acids;Sugars;Vitamins;Food and Feed Additive;Inhibitors Mol File: 134-03-2.mol   Sodium ascorbate Chemical Properties Melting point  220 °C (dec.)(lit.) alpha  104 º (c=1, H2O 25 ºC) Boiling point  235 °C density  1.66 refractive index  105.5 ° (C=10, H2O) storage temp.  2-8°C solubility  H2O: 50 mg/mL form  powder color  white to slightly yellow Odor odorless PH 7.48(1 mM solution);7.71(10 mM solution);7.64(100 mM solution);7.62(1000 mM solution) optical activity [α]20/D +105±2°, c = 5% in H2O Water Solubility  620 g/L (20 ºC) Merck  14,830 BRN  3767246 Stability: Stable. Incompatible with strong oxidizing agents. CAS DataBase Reference 134-03-2(CAS DataBase Reference) EPA Substance Registry System Sodium ascorbate (134-03-2)   Safety Information Risk Statements  68 Safety Statements  24/25 WGK Germany  1 RTECS  CI7671000 TSCA  Yes HS Code  29362700 Hazardous Substances Data 134-03-2(Hazardous Substances Data) Toxicity sce-hmn:lym 100 mmol/L MUREAV 60,321,79 MSDS Information Provider Language L-Ascorbic acid sodium salt English SigmaAldrich English ACROS English ALFA English   Sodium ascorbate Usage And Synthesis Description Sodium ascorbate is sodium salt of ascorbic acid (commonly known as vitamin C), which is approved for use as a food additive in many countries. Sodium ascorbate is consisted of a combination of sodium and vitamin C, which commonly serve as an antioxidant and an acidity regulator in pharmaceutical manufacturing and in the food industry. In this mixture, sodium acts as a buffer, creating a less acidic supplement than those made entirely from vitamin C. It can be easier to tolerate if the digestive system is sensitive to acid. As a vitamin C supplement, it provides both sodium and vitamin C for human body, which is effective to prevent or treat vitamin C deficiency. Besides, studies have shown that taking sodium ascorbate is helpful with cancer prevention and treatment. References # # # Chemical Properties Sodium ascorbate occurs as a white or slightly yellow-colored, practically odorless, crystalline powder with a pleasant saline taste. Uses Sodium Ascorbate is an antioxidant that is the sodium form of ascorbic acid. it is soluble in water and provides a nonacidic taste. a 10% aqueous solution has a ph of 7.3–7.6. in water, it readily reacts with atmospheric oxygen and other oxidizing agents, making it valuable as an antioxidant. one part sodium ascorbate is equivalent to 1.09 parts of sodium erythorbate. see ascorbic acid. Uses L-Ascorbic acid (Vitamin C) is a water soluble molecule used in a wide variety of applications, including cell culture, as a reducing agent that helps reduce oxidative stress. Uses As antimicrobial and antioxidant in foodstuffs. Definition ChEBI: Sodium ascorbate is an organic sodium salt resulting from the replacement of the proton from the 3-hydroxy group of ascorbic acid by a sodium ion. It has a role as a food antioxidant, a flour treatment agent, a coenzyme, a plant metabolite, a human metabolite, a Daphnia magna metabolite and a reducing agent. It is an organic sodium salt and a vitamin C. It contains a L-ascorbate. Production Methods An equivalent amount of sodium bicarbonate is added to a solution of ascorbic acid in water. Following the cessation of effervescence, the addition of propan-2-ol precipitates sodium ascorbate. Brand name Ascorbin (Marion Merrell Dow). General Description Minute crystals or white powder. pH of aqueous solutions 5.6 to 7.0 or even higher (a 10% solution, made from a commercial grade, may have a pH of 7.4 to 7.7). Air & Water Reactions Water soluble. Aqueous solutions are subject to quick air oxidation at pH greater than 6.0. Reactivity Profile A weak base. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydroxide ions and have pH's greater than 7.0. They react as bases to neutralize acids. These neutralizations generate heat, but less or far less than is generated by neutralization of the bases in reactivity group 10 (Bases) and the neutralization of amines. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Health Hazard SYMPTOMS: Ingestion of 10 grams or more of this type of compound may cause diarrhea. Fire Hazard Flash point data for Sodium ascorbate are not available. Sodium ascorbate is probably combustible. Pharmaceutical Applications Sodium ascorbate is used as an antioxidant in pharmaceutical formulations, and also in food products where it increases the effectiveness of sodium nitrite against growth of Listeria monocytogenes in cooked meats. It improves gel cohesiveness and sensory firmness of fiberized products regardless of vacuum treatment. It is also used therapeutically as a source of vitamin C in tablets and parenteral preparations. Biochem/physiol Actions Ascorbic acid exhibits anti-oxidant properties. It is a primary substrate for detoxifying hydrogen peroxide. Ascorbic acid is a co-factor for the synthesis of adrenal steroids and catecholamines. L-Ascorbic acid (Vitamin C) is a water soluble molecule used in a wide variety of applications, including cell culture, as a reducing agent that helps reduce oxidative stress. L-Ascorbate can be regenerated by biological systems. Safety Profile Human mutation data reported. When heated to decomposition it emits toxic fumes of Na2O. Safety The parenteral administration of 0.25-1.00 g of sodium ascorbate, given daily in divided doses, is recommended in the treatment of vitamin C deficiencies. Various adverse reactions have been reported following the administration of 1 g or more of sodium ascorbate, although ascorbic acid and sodium ascorbate are usually well tolerated; see Ascorbic acid. There have been no reports of adverse effects associated with the much lower concentrations of sodium ascorbate and ascorbic acid, which are employed as antioxidants. The WHO has set an acceptable daily intake of ascorbic acid, potassium ascorbate, and sodium ascorbate, as antioxidants in food, at up to 15 mg/kg body-weight in addition to that naturally present in food. storage Sodium ascorbate is relatively stable in air, although it gradually darkens on exposure to light. Aqueous solutions are unstable and subject to rapid oxidation in air at pH > 6.0. The bulk material should be stored in a well-closed nonmetallic container, protected from light, in a cool, dry place. Incompatibilities Incompatible with oxidizing agents, heavy metal ions, especially copper and iron, methenamine, sodium nitrite, sodium salicylate, and theobromine salicylate. The aqueous solution is reported to be incompatible with stainless steel filters. Regulatory Status GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (IV preparations; oral tablets). Included in nonparenteral and parenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.   Sodium ascorbate Preparation Products And Raw materials Raw materials L(+)-Ascorbic acid Preparation Products L(+)-Ascorbic acid