China Largest Factory Manufacturer sales L-LEUCIC ACID CAS 13748-90-8 CAS NO.13748-90-8

                                PRODUCT DETAILS       

L-LEUCIC ACID Basic information Product Name: L-LEUCIC ACID Synonyms: (s)-pentanoicaci;(S)-(-)-2-HYDROXYISOCAPROIC ACID;(S)-2-HYDROXY-4-METHYLVALERIC ACID;2-HYDROXY-3-METHYLVALERIC ACID;2-HYDROXY-3-METHYLPENTANOIC ACID;L-2-hydroxy-4-methylvaleric acid;LEUCIC ACID;L-LEUCIC ACID CAS: 13748-90-8 MF: C6H12O3 MW: 132.16 EINECS: 237-329-6 Product Categories: API intermediates;Carboxylic Acids (Chiral);chiral;Chiral Building Blocks;Synthetic Organic Chemistry Mol File: 13748-90-8.mol   L-LEUCIC ACID Chemical Properties Melting point  78-80 °C(lit.) Boiling point  277.83°C (rough estimate) density  1.0160 (rough estimate) refractive index  -26 ° (C=2, 1 %NaOH) storage temp.  Sealed in dry,Room Temperature solubility  Aqueous Base (Slightly), DMSO (Sparingly), Water (Slightly) form  Solid pka 3.86±0.21(Predicted) color  White to Off-White optical activity [α]22/D 26.3°, c = 1 in 1 M NaOH Water Solubility  almost transparency CAS DataBase Reference 13748-90-8(CAS DataBase Reference) EPA Substance Registry System Pentanoic acid, 2-hydroxy-4-methyl-, (2S)- (13748-90-8)   Safety Information Safety Statements  24/25 WGK Germany  3 HS Code  29181990 MSDS Information Provider Language SigmaAldrich English   L-LEUCIC ACID Usage And Synthesis Chemical Properties white to light yellow crystal powde Uses L-Leucic Acid is a reagent in the synthesis of cryptophycins based macrocyclic depsipeptides which are used as tubulin inhibitors. Definition ChEBI: The (S)-enantiomer of 2-hydroxy-4-methylpentanoic acid. Derived from the metabolism of the branched-chain amino acids, it belongs to the 2-hydroxycarboxylic acid group of amino acid metabolites.   L-LEUCIC ACID Preparation Products And Raw materials Raw materials Pentanoic acid, 2-bromo-4-methyl-, ethyl ester, (S)- (9CI)-->4-Methyl-2-oxovaleric acid-->L-Tyrosine-->β-Alanine-->L-Leucine-->Isovaleraldehyde Preparation Products (R)-2-HYDROXY-4-METHYLPENTANOIC ACID-->R-b-aminoisobutyric acid

                                                                About Our Group

Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

                                                                      Our Group profiles

Our Factories production lines

                                                   Our Factories R&D ability

                        Our Factories warehouse 

                                                       Product information

L-LEUCIC ACID Basic information Product Name: L-LEUCIC ACID Synonyms: (s)-pentanoicaci;(S)-(-)-2-HYDROXYISOCAPROIC ACID;(S)-2-HYDROXY-4-METHYLVALERIC ACID;2-HYDROXY-3-METHYLVALERIC ACID;2-HYDROXY-3-METHYLPENTANOIC ACID;L-2-hydroxy-4-methylvaleric acid;LEUCIC ACID;L-LEUCIC ACID CAS: 13748-90-8 MF: C6H12O3 MW: 132.16 EINECS: 237-329-6 Product Categories: API intermediates;Carboxylic Acids (Chiral);chiral;Chiral Building Blocks;Synthetic Organic Chemistry Mol File: 13748-90-8.mol   L-LEUCIC ACID Chemical Properties Melting point  78-80 °C(lit.) Boiling point  277.83°C (rough estimate) density  1.0160 (rough estimate) refractive index  -26 ° (C=2, 1 %NaOH) storage temp.  Sealed in dry,Room Temperature solubility  Aqueous Base (Slightly), DMSO (Sparingly), Water (Slightly) form  Solid pka 3.86±0.21(Predicted) color  White to Off-White optical activity [α]22/D 26.3°, c = 1 in 1 M NaOH Water Solubility  almost transparency CAS DataBase Reference 13748-90-8(CAS DataBase Reference) EPA Substance Registry System Pentanoic acid, 2-hydroxy-4-methyl-, (2S)- (13748-90-8)   Safety Information Safety Statements  24/25 WGK Germany  3 HS Code  29181990 MSDS Information Provider Language SigmaAldrich English   L-LEUCIC ACID Usage And Synthesis Chemical Properties white to light yellow crystal powde Uses L-Leucic Acid is a reagent in the synthesis of cryptophycins based macrocyclic depsipeptides which are used as tubulin inhibitors. Definition ChEBI: The (S)-enantiomer of 2-hydroxy-4-methylpentanoic acid. Derived from the metabolism of the branched-chain amino acids, it belongs to the 2-hydroxycarboxylic acid group of amino acid metabolites.   L-LEUCIC ACID Preparation Products And Raw materials Raw materials Pentanoic acid, 2-bromo-4-methyl-, ethyl ester, (S)- (9CI)-->4-Methyl-2-oxovaleric acid-->L-Tyrosine-->β-Alanine-->L-Leucine-->Isovaleraldehyde Preparation Products (R)-2-HYDROXY-4-METHYLPENTANOIC ACID-->R-b-aminoisobutyric acid