China Original Largest Manufacturer sales N4-Acetylcytosine CAS 14631-20-0 CAS NO.14631-20-0

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N4-Acetylcytosine Basic information Product Name: N4-Acetylcytosine Synonyms: n-(1,2-dihydro-2-oxo-4-pyrimidinyl)-acetamid;N-ACETYLCYTOSINE;N4-ACETYLCYTOSINE;LABOTEST-BB LT00012625;4-Acetylamino-2-hydroxypyrimidine;N-Acetocytosine;N(4)-Acetylcytosine,98%;N-Actyl cytosine CAS: 14631-20-0 MF: C6H7N3O2 MW: 153.14 EINECS: 619-683-7 Product Categories: Heterocyclic Compounds;Building Blocks;Biochemistry;Nucleobases and their analogs;Heterocyclic Building Blocks;Pyrimidines;Nucleosides, Nucleotides & Related Reagents Mol File: 14631-20-0.mol   N4-Acetylcytosine Chemical Properties Melting point  >300 °C (lit.) density  1.41±0.1 g/cm3(Predicted) storage temp.  Sealed in dry,Room Temperature solubility  DMSO (Sparingly), Methanol (Very Slightly) form  Solid pka 7.60±0.10(Predicted) color  Off-White to Pale Beige BRN  138451 CAS DataBase Reference 14631-20-0(CAS DataBase Reference)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  22-24/25-37/39-26-37 WGK Germany  3 HS Code  29335995 MSDS Information Provider Language SigmaAldrich English ALFA English   N4-Acetylcytosine Usage And Synthesis Chemical Properties Crstalline powder Uses N4-Acetylcytosine may be used in the preparation of cytidine. It may be used in the preparation of 1-(4-azido-4-deoxy-β-D-glucopyranosyl)cytosine. General Description Four stable conformers of N4-acetylcytosine, and the one of the stable form containing an intramoleuclar six-membered ring have been reported by theoretical calculations.The infrared and FT-Raman spectra of N4-acetylcytosine in the solid phase has been reported. Purification Methods If TLC or paper chromatography shows that it contains unacetylated cytosine, then reflux it in Ac2O for 4hours, cool at 3-4o for a few days, collect the crystals, wash them with cold H2O, then EtOH and dry at 100o. It is insoluble in EtOH and dissolves in H2O with difficulty, but crystallises in prisms from hot H2O. It is hydrolysed by 80% aqueous AcOH at 100o/1hour. [UV: Brown et al. J Chem Soc 2384 1956, Codington et al. J Am Chem Soc 80 5164 1958.] It forms an Hg salt [Fox et al. J Am Chem Soc 79 5060 1957]. [Beilstein 25 III/IV 3657.]   N4-Acetylcytosine Preparation Products And Raw materials Preparation Products 4-Amino-1-(2-deoxy-2,2-difluoro-a-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone Hydrochloride

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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N4-Acetylcytosine Basic information Product Name: N4-Acetylcytosine Synonyms: n-(1,2-dihydro-2-oxo-4-pyrimidinyl)-acetamid;N-ACETYLCYTOSINE;N4-ACETYLCYTOSINE;LABOTEST-BB LT00012625;4-Acetylamino-2-hydroxypyrimidine;N-Acetocytosine;N(4)-Acetylcytosine,98%;N-Actyl cytosine CAS: 14631-20-0 MF: C6H7N3O2 MW: 153.14 EINECS: 619-683-7 Product Categories: Heterocyclic Compounds;Building Blocks;Biochemistry;Nucleobases and their analogs;Heterocyclic Building Blocks;Pyrimidines;Nucleosides, Nucleotides & Related Reagents Mol File: 14631-20-0.mol   N4-Acetylcytosine Chemical Properties Melting point  >300 °C (lit.) density  1.41±0.1 g/cm3(Predicted) storage temp.  Sealed in dry,Room Temperature solubility  DMSO (Sparingly), Methanol (Very Slightly) form  Solid pka 7.60±0.10(Predicted) color  Off-White to Pale Beige BRN  138451 CAS DataBase Reference 14631-20-0(CAS DataBase Reference)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  22-24/25-37/39-26-37 WGK Germany  3 HS Code  29335995 MSDS Information Provider Language SigmaAldrich English ALFA English   N4-Acetylcytosine Usage And Synthesis Chemical Properties Crstalline powder Uses N4-Acetylcytosine may be used in the preparation of cytidine. It may be used in the preparation of 1-(4-azido-4-deoxy-β-D-glucopyranosyl)cytosine. General Description Four stable conformers of N4-acetylcytosine, and the one of the stable form containing an intramoleuclar six-membered ring have been reported by theoretical calculations.The infrared and FT-Raman spectra of N4-acetylcytosine in the solid phase has been reported. Purification Methods If TLC or paper chromatography shows that it contains unacetylated cytosine, then reflux it in Ac2O for 4hours, cool at 3-4o for a few days, collect the crystals, wash them with cold H2O, then EtOH and dry at 100o. It is insoluble in EtOH and dissolves in H2O with difficulty, but crystallises in prisms from hot H2O. It is hydrolysed by 80% aqueous AcOH at 100o/1hour. [UV: Brown et al. J Chem Soc 2384 1956, Codington et al. J Am Chem Soc 80 5164 1958.] It forms an Hg salt [Fox et al. J Am Chem Soc 79 5060 1957]. [Beilstein 25 III/IV 3657.]   N4-Acetylcytosine Preparation Products And Raw materials Preparation Products 4-Amino-1-(2-deoxy-2,2-difluoro-a-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone Hydrochloride