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China Biggest Factory Manufacturer supply Chromium Picolinate CAS 14639-25-9 500MT/Year CAS NO.14639-25-9
- FOB Price: USD: 1.00-2.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,MoneyGram,Other
- Available Specifications:
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- Product Details
Keywords
- Chromium Picolinate
- Chromium Picolinate
- 14639-25-9
Quick Details
- ProName: China Biggest Factory Manufacturer sup...
- CasNo: 14639-25-9
- Molecular Formula: 14639-25-9
- Appearance: white powder
- Application: Pharm chemicals industry
- DeliveryTime: 3-5 days
- PackAge: 25KG/Drum
- Port: Shanghai Guangzhou Qingdao Shenzhen
- ProductionCapacity: 20 Metric Ton/Month
- Purity: 99%
- Storage: 2-8°C
- Transportation: By air /Sea/ coruier
- LimitNum: 1 Kilogram
- Heavy Metal: 1
- Limited Quantity: 1
- Valid Period: 2
- Color: Red
- Melting point: ≥350°C
- Boiling point: 363.24°C (rough estimate)
- density: 1.667
- solubility: 1 M NaOH: 10 mg/mL, dark green
- Water Solubility: <0.1 g/100 mL at 21 oC
- Stability: Stable. Combustible. Incompatible with...
Superiority
| Chromium picolinate Basic information |
| Product Name: | Chromium picolinate |
| Synonyms: | facial chromium(III) picolinate;ChroChromium(III) picolinateChromium(III) picolinateChromium(III) picolinatemium(III) picolinate;CrPic;Picolinic acid chromium;CHROMIUM PICOLINATE NF;Picolinic Acid Chromium(III) Salt Chromium(III) Pyridine-2-carboxylate Pyridine-2-carboxylic Acid Chromium(III) Salt;ChromiumPiconilate;Chromium, tris(2-pyridinecarboxylato-.kappa.N1,.kappa.O2)- |
| CAS: | 14639-25-9 |
| MF: | C18H12CrN3O6 |
| MW: | 418.31 |
| EINECS: | 1592732-453-0 |
| Product Categories: | Food additives;Classes of Metal Compounds;Cr (Chromium) Compounds;Transition Metal Compounds;14639-25-9 |
| Mol File: | 14639-25-9.mol |
| Chromium picolinate Chemical Properties |
| Melting point | >300°C |
| storage temp. | room temp |
| solubility | DMSO (Slightly, Heated) |
| form | Solid |
| color | Dark Red |
| Merck | 14,2236 |
| InChIKey | CBDQOLKNTOMMTL-UHFFFAOYSA-K |
| CAS DataBase Reference | 14639-25-9(CAS DataBase Reference) |
| EPA Substance Registry System | Chromium, tris(2-pyridinecarboxylato-.kappa.N1,.kappa.O2)- (14639-25-9) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 22-36/37/39-36-26 |
| WGK Germany | 3 |
| RTECS | US5647790 |
| HS Code | 29333990 |
| MSDS Information |
| Provider | Language |
|---|---|
| Picolinic acid chromium(III) salt | English |
| Chromium picolinate Usage And Synthesis |
| Benefits | chromium Picolinate is a nutritional supplement that is needed in the body but in small amounts. It gives the body the muscle mass that it needs. It also ebbs out the bad fat as it increases muscle mass. Chromium Picolinate, like all herbs and minerals, it would be taken with the needed herbs to ensure proper function and good health in the body. Chromium Picolinate maintains the bodybuilding effect and nourishes the blood system. Chromium Picolinate helps maintain the good condition of a body that is gaining muscle, it helps maintain the blood pressure and blood sugar. After a hard day,Chromium Picolinate relaxes the muscle as it gains strength. stress is a daily occurrence in life,working out is work and may even tear muscles. Taking the Chromium Picolinate gives more of an assurance to the body muscles than not taking it at all. The Chromium Picolinate removes metals and toxins from the body system. It also removes mercury that may have been digested while eating, if there is a mercury filled metal inside the teeth. Gaining muscles also means having the need for energy.Moving about daily is so stressful it can cause the blood sugar to rise. It can cause blood pressure too. The Chromium Picolinate regulates the blood pressure, blood sugar and maintains the insulin in the body system to avoid any type of diabetes. |
| Chemical properties | Chromium picolinate appears as fine purple crystalline powder with good fluidity. It is chemically stable at room temperature and is slightly soluble in water but insoluble in ethanol, wherein the chromium is in the trivalent form. The whole molecule structure is electrically neutral and has hydrophobic properties. Therefore, it is possible to perform the trans-membrane absorption on the intact structure with the molecular structure being similar to the GTF part. |
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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research. Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products. Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation. We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.
Details
| Chromium picolinate Basic information |
| Product Name: | Chromium picolinate |
| Synonyms: | facial chromium(III) picolinate;ChroChromium(III) picolinateChromium(III) picolinateChromium(III) picolinatemium(III) picolinate;CrPic;Picolinic acid chromium;CHROMIUM PICOLINATE NF;Picolinic Acid Chromium(III) Salt Chromium(III) Pyridine-2-carboxylate Pyridine-2-carboxylic Acid Chromium(III) Salt;ChromiumPiconilate;Chromium, tris(2-pyridinecarboxylato-.kappa.N1,.kappa.O2)- |
| CAS: | 14639-25-9 |
| MF: | C18H12CrN3O6 |
| MW: | 418.31 |
| EINECS: | 1592732-453-0 |
| Product Categories: | Food additives;Classes of Metal Compounds;Cr (Chromium) Compounds;Transition Metal Compounds;14639-25-9 |
| Mol File: | 14639-25-9.mol |
| Chromium picolinate Chemical Properties |
| Melting point | >300°C |
| storage temp. | room temp |
| solubility | DMSO (Slightly, Heated) |
| form | Solid |
| color | Dark Red |
| Merck | 14,2236 |
| InChIKey | CBDQOLKNTOMMTL-UHFFFAOYSA-K |
| CAS DataBase Reference | 14639-25-9(CAS DataBase Reference) |
| EPA Substance Registry System | Chromium, tris(2-pyridinecarboxylato-.kappa.N1,.kappa.O2)- (14639-25-9) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 22-36/37/39-36-26 |
| WGK Germany | 3 |
| RTECS | US5647790 |
| HS Code | 29333990 |
| MSDS Information |
| Provider | Language |
|---|---|
| Picolinic acid chromium(III) salt | English |
| Chromium picolinate Usage And Synthesis |
| Benefits | chromium Picolinate is a nutritional supplement that is needed in the body but in small amounts. It gives the body the muscle mass that it needs. It also ebbs out the bad fat as it increases muscle mass. Chromium Picolinate, like all herbs and minerals, it would be taken with the needed herbs to ensure proper function and good health in the body. Chromium Picolinate maintains the bodybuilding effect and nourishes the blood system. Chromium Picolinate helps maintain the good condition of a body that is gaining muscle, it helps maintain the blood pressure and blood sugar. After a hard day,Chromium Picolinate relaxes the muscle as it gains strength. stress is a daily occurrence in life,working out is work and may even tear muscles. Taking the Chromium Picolinate gives more of an assurance to the body muscles than not taking it at all. The Chromium Picolinate removes metals and toxins from the body system. It also removes mercury that may have been digested while eating, if there is a mercury filled metal inside the teeth. Gaining muscles also means having the need for energy.Moving about daily is so stressful it can cause the blood sugar to rise. It can cause blood pressure too. The Chromium Picolinate regulates the blood pressure, blood sugar and maintains the insulin in the body system to avoid any type of diabetes. |
| Chemical properties | Chromium picolinate appears as fine purple crystalline powder with good fluidity. It is chemically stable at room temperature and is slightly soluble in water but insoluble in ethanol, wherein the chromium is in the trivalent form. The whole molecule structure is electrically neutral and has hydrophobic properties. Therefore, it is possible to perform the trans-membrane absorption on the intact structure with the molecular structure being similar to the GTF part. |
| Chromium picolinate Basic information |
| Product Name: | Chromium picolinate |
| Synonyms: | facial chromium(III) picolinate;ChroChromium(III) picolinateChromium(III) picolinateChromium(III) picolinatemium(III) picolinate;CrPic;Picolinic acid chromium;CHROMIUM PICOLINATE NF;Picolinic Acid Chromium(III) Salt Chromium(III) Pyridine-2-carboxylate Pyridine-2-carboxylic Acid Chromium(III) Salt;ChromiumPiconilate;Chromium, tris(2-pyridinecarboxylato-.kappa.N1,.kappa.O2)- |
| CAS: | 14639-25-9 |
| MF: | C18H12CrN3O6 |
| MW: | 418.31 |
| EINECS: | 1592732-453-0 |
| Product Categories: | Food additives;Classes of Metal Compounds;Cr (Chromium) Compounds;Transition Metal Compounds;VX:15689727968 |
| Mol File: | 14639-25-9.mol |
| Chromium picolinate Chemical Properties |
| Melting point | >300°C |
| storage temp. | room temp |
| solubility | DMSO (Slightly, Heated) |
| form | Solid |
| color | Dark Red |
| Merck | 14,2236 |
| InChIKey | CBDQOLKNTOMMTL-UHFFFAOYSA-K |
| CAS DataBase Reference | 14639-25-9(CAS DataBase Reference) |
| EPA Substance Registry System | Chromium, tris(2-pyridinecarboxylato-.kappa.N1,.kappa.O2)- (14639-25-9) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 22-36/37/39-36-26 |
| WGK Germany | 3 |
| RTECS | US5647790 |
| HS Code | 29333990 |
| MSDS Information |
| Provider | Language |
|---|---|
| Picolinic acid chromium(III) salt | English |
| Chromium picolinate Usage And Synthesis |
| Benefits | chromium Picolinate is a nutritional supplement that is needed in the body but in small amounts. It gives the body the muscle mass that it needs. It also ebbs out the bad fat as it increases muscle mass. Chromium Picolinate, like all herbs and minerals, it would be taken with the needed herbs to ensure proper function and good health in the body. Chromium Picolinate maintains the bodybuilding effect and nourishes the blood system. Chromium Picolinate helps maintain the good condition of a body that is gaining muscle, it helps maintain the blood pressure and blood sugar. After a hard day,Chromium Picolinate relaxes the muscle as it gains strength. stress is a daily occurrence in life,working out is work and may even tear muscles. Taking the Chromium Picolinate gives more of an assurance to the body muscles than not taking it at all. The Chromium Picolinate removes metals and toxins from the body system. It also removes mercury that may have been digested while eating, if there is a mercury filled metal inside the teeth. Gaining muscles also means having the need for energy.Moving about daily is so stressful it can cause the blood sugar to rise. It can cause blood pressure too. The Chromium Picolinate regulates the blood pressure, blood sugar and maintains the insulin in the body system to avoid any type of diabetes. |
| Chemical properties | Chromium picolinate appears as fine purple crystalline powder with good fluidity. It is chemically stable at room temperature and is slightly soluble in water but insoluble in ethanol, wherein the chromium is in the trivalent form. The whole molecule structure is electrically neutral and has hydrophobic properties. Therefore, it is possible to perform the trans-membrane absorption on the intact structure with the molecular structure being similar to the GTF part. In 1977, Toepfer thought that GTF is the biologically active form of chromium with its structure being the complex formed between nicotinic acid chromium and aspartic acid, glutamic acid, glycine and cysteine. The GTF-like structure of chromium picolinate class determines its own excellent absorption rate and can more effectively play its biological function. It is reported that the absorption rate of formulation of ordinary chromium was about 0.5% while the absorption rate of chromium is 2%-5% (Anderson, 1996). |
| Uses | Chromium picolinate, a complex of trivalent chromium and picolinic acid, is better absorbed (2-5%) than dietary chromium.It is widely included in dietary supplements, espe-cially in multivitamin, multimineral products. These supplements are usu-ally available in capsule or tablet form. Typical amounts of chromium picolinate used in multivitamin,multimineral dietary supplements range from 50 to 400 uglday. Specialtydietary supplements may contain much more chromium picolinate and mayinclude other forms of both chromium and picolinate.Chromium picolinateis also readily available in single-ingredient preparations or in combinationwith a few ingredients. Chromium picolinate has been used successfully to control blood cholesterol and blood glucose levels. It also promotes the loss of fat and an increase in lean muscle tissue.Studies show it may increase longevity and help to fight osteoporosis. Chromium picolinate (CrPic) is taken as the supplement or alternative medicine for type 2 diabetes. Experimental evidence has indicated CrPic boost glucose uptake via activating P38 MAPK. Chromium is thought to be able to enhance the action of insulin, thereby increasing insulin sensitivity in type 2 diabetes patients. |
| Side effects | Chromium picolinate has been associated with adverse effects. Unlike other forms of chromium,chromium picolinate moves from the bloodstream into cells intact, and then dissociates, and toxicity may be related to accumulation of intracellular chromium III ions or accumulation of picolinic acid. It has been associated with enhanced production of hydroxyl radicals,depletion of antioxidant enzymes,DNA damage and mutagenesis.Comparative cell studies of chromium picolinate and niacin-bound chromium have shown that chromium picolinate produces a greater amountof oxidative stress and DNA damage, and the picolinic acid component is believed to be largely responsible.In animals, it has been found to cause oxidative damage to lipids and DNA.However, in a short-term study, animals given 33,250 or 2000 mg/kg of chromium picolinate,equivalent to 4.1,30.8 and 246 mg/kg of chromium,showed no evidence of chromosomal damage in their bone marrow cells. Chromium picolinate has been implicated in a variety of adverse effects，including kidney and liver dysfunction, skin blisters and pustules,anaemia, haemolysis, tissue oedema and nerve damage.Many of the proposed adverse effects in humans are based on case reports in which chromium picolinate has not been proven to be the causative factor.In 2004,the UK Committee on Mutagenicity of Chemicals in Food，Consumer Products and the Environment reviewed the evidence, and concluded that the balance of the evidence suggested that chromium picolinate was not genotoxic, and that its use should not be restricted. |
| Chemical Properties | Dark violet crystal |
| Uses |
Chromium picolinate (CrPic), a dietay supplement, may be used to study its potential as a modulator of glucose uptake and the activity of insulin. CrPic is used to study its effects on nuclear factor-κ B (NF-κB) and nuclear factor-E2-related factor-2 (Nrf2) pathways in animals. |
| General Description |
Chromium picolinate is a supplemental or alternative medication for type 2 diabetes and an anti-diabetic mechanisms of CrPic in insulin-resistant 3T3-L1 adipocytes. |
| Biochem/physiol Actions | Chromium picolinate (CrPic) is a supplemental or alternative medication for type 2 diabetes. Experimental evidence shows the effect of CrPic on glucose uptake through the activation of p38 MAPK. Chromium is thought to potentiate the action of insulin, leading to increased insulin sensitivity in type 2 diabetes. |
| Chromium picolinate Preparation Products And Raw materials |