ISO.HACCP.GMP.FDA.SGS.BV-China Largest Manufacturer factory Supply Cysteamine Hydrochloride CAS 156-57-0 CAS NO.156-57-0

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Cysteamine hydrochloride Basic information Product Name: Cysteamine hydrochloride Synonyms: mercaptoethylammonium chloride;Mercaptamine hydrochloride;DECARBOXYCYSTEINE HCL;DECARBOXYCYSTEINE HYDROCHLORIDE;CYSTEAMINIUM CHLORIDE;CYSTEAMINE HCL;CYSTEAMINE HYDROCHLORIDE;BETA-MERCAPTOETHYLAMINE HYDROCHLORIDE CAS: 156-57-0 MF: C2H8ClNS MW: 113.61 EINECS: 205-858-1 Product Categories: API intermediates;Antioxidant;Biochemistry;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Pharmaceutical Intermediates;Sulfur compounds;Starting Raw Materials & Intermediates;Anilines, Aromatic Amines and Nitro Compounds;proteinmod;produce cosmetics,feed additive,biochemical reagent;Inhibitors Mol File: 156-57-0.mol   Cysteamine hydrochloride Chemical Properties Melting point  67-71 °C density  0.75 refractive index  1.6100 (estimate) storage temp.  2-8°C solubility  H2O: 1 m at 20 °C, clear, colorless form  Crystalline Powder or Pellets color  White PH 3.3-5.0 (400g/l, H2O, 20℃) Water Solubility  VERY SOLUBLE λmax λ: 280 nm Amax: ≤0.3 Sensitive  Hygroscopic Merck  14,2779 BRN  3590083 Stability: Stable, but hygroscopic. Incompatible with strong oxidizing agents. InChIKey OGMADIBCHLQMIP-UHFFFAOYSA-N CAS DataBase Reference 156-57-0(CAS DataBase Reference) EPA Substance Registry System Cysteamine hydrochloride (156-57-0)   Safety Information Hazard Codes  Xn,Xi Risk Statements  22-36/37/38 Safety Statements  36/37/39-26-36 RIDADR  UN 3335 WGK Germany  3 RTECS  KJ0200000 F  1-3-10-13 TSCA  Yes HS Code  29309070 Toxicity LD50 orally in Rabbit: 642 mg/kg MSDS Information Provider Language Cysteamine hydrochloride English ACROS English SigmaAldrich English ALFA English   Cysteamine hydrochloride Usage And Synthesis Description Cysteamine is a stable aminothiol with radioprotective activities. It reduces ionizing radiation-induced death and chromosomal damage in mice in a dose-dependent manner. Cysteamine binds rapidly and temporarily to plasma proteins upon administration and this activity is directly correlated to its radioprotective effects. In vitro, 0.1 mM cysteamine depletes 90% of free cystine from cystinotic fibroblasts. Formulations containing cysteamine have been used to treat nephropathic cystinosis and reduce glomerular deterioration in humans. Chemical Properties White Solid Uses Cysteamine hydrochloride is used as an antioxidant and in radiation therapy. Uses Cysteamine hydrochloride has been used in the in-situ generation of chiral cysteamine-capped cadmium sulfide quantum dots (CA-CdS QDs) for the sensing of Cd2+ and S2-. Uses An inhibitor of DMBA-induced mammary tumors2-Mercaptoethylamine hydrochloride acts as a precursor in taurine biosynthesis and component of coenzyme A. It is involved in the preparation of active pharmaceutical ingredients like ranitidine and nizatidine. It acts as an antidote for acetaminophen poisoning. Further, it is used in the oral treatment of nephropathic cystinosis, radiation sickness and disorders of cysteine excretion. In addition to this, it serves as an antioxidant and an inhibitor of 7,12-Dimethylbenz[a]anthracene (DMBA)-induced tumors. General Description Cysteamine is an aminothiol that can reduce important oxidized disulfide molecules such as cystine to yield cysteine. Hazard Toxic by inhalation and ingestion. Biochem/physiol Actions Cysteamine is an aminothiol that can reduce important oxidized disulfide molecules such as cystine to yield cysteine. Cysteamine is used in a wide range of applications from regulation of gene expression, to depletion of somatostatin, to coating of nanoparticles. Purification Methods Purify the salt by recrystallisation from EtOH. It is freely soluble in H2O and should be stored in a dry atmosphere. [Mills & Bogert J Am Chem Soc 62 1177 1940.] The picrate has m 125-126o; see previous entry for free base. [Beilstein 4 IV 1570.]   Cysteamine hydrochloride Preparation Products And Raw materials Raw materials Hydrochloric acid-->Sulfuric acid-->Carbon disulfide-->Ethanolamine Preparation Products 1,3-THIAZOLIDIN-2-ONE-->2-AMINOETHYLMETHYLSULFONE HYDROCHLORIDE-->THIAZOLIDINE-->Cystamine dihydrochloride-->N-(2-MERCAPTOETHYL)ACETAMIDE-->Thiazolidine, hydrochloride (1:1)-->2-METHYLTHIAZOLIDINE

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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Cysteamine hydrochloride Basic information Product Name: Cysteamine hydrochloride Synonyms: mercaptoethylammonium chloride;Mercaptamine hydrochloride;DECARBOXYCYSTEINE HCL;DECARBOXYCYSTEINE HYDROCHLORIDE;CYSTEAMINIUM CHLORIDE;CYSTEAMINE HCL;CYSTEAMINE HYDROCHLORIDE;BETA-MERCAPTOETHYLAMINE HYDROCHLORIDE CAS: 156-57-0 MF: C2H8ClNS MW: 113.61 EINECS: 205-858-1 Product Categories: API intermediates;Antioxidant;Biochemistry;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Pharmaceutical Intermediates;Sulfur compounds;Starting Raw Materials & Intermediates;Anilines, Aromatic Amines and Nitro Compounds;proteinmod;produce cosmetics,feed additive,biochemical reagent;Inhibitors Mol File: 156-57-0.mol   Cysteamine hydrochloride Chemical Properties Melting point  67-71 °C density  0.75 refractive index  1.6100 (estimate) storage temp.  2-8°C solubility  H2O: 1 m at 20 °C, clear, colorless form  Crystalline Powder or Pellets color  White PH 3.3-5.0 (400g/l, H2O, 20℃) Water Solubility  VERY SOLUBLE λmax λ: 280 nm Amax: ≤0.3 Sensitive  Hygroscopic Merck  14,2779 BRN  3590083 Stability: Stable, but hygroscopic. Incompatible with strong oxidizing agents. InChIKey OGMADIBCHLQMIP-UHFFFAOYSA-N CAS DataBase Reference 156-57-0(CAS DataBase Reference) EPA Substance Registry System Cysteamine hydrochloride (156-57-0)   Safety Information Hazard Codes  Xn,Xi Risk Statements  22-36/37/38 Safety Statements  36/37/39-26-36 RIDADR  UN 3335 WGK Germany  3 RTECS  KJ0200000 F  1-3-10-13 TSCA  Yes HS Code  29309070 Toxicity LD50 orally in Rabbit: 642 mg/kg MSDS Information Provider Language Cysteamine hydrochloride English ACROS English SigmaAldrich English ALFA English   Cysteamine hydrochloride Usage And Synthesis Description Cysteamine is a stable aminothiol with radioprotective activities. It reduces ionizing radiation-induced death and chromosomal damage in mice in a dose-dependent manner. Cysteamine binds rapidly and temporarily to plasma proteins upon administration and this activity is directly correlated to its radioprotective effects. In vitro, 0.1 mM cysteamine depletes 90% of free cystine from cystinotic fibroblasts. Formulations containing cysteamine have been used to treat nephropathic cystinosis and reduce glomerular deterioration in humans. Chemical Properties White Solid Uses Cysteamine hydrochloride is used as an antioxidant and in radiation therapy. Uses Cysteamine hydrochloride has been used in the in-situ generation of chiral cysteamine-capped cadmium sulfide quantum dots (CA-CdS QDs) for the sensing of Cd2+ and S2-. Uses An inhibitor of DMBA-induced mammary tumors2-Mercaptoethylamine hydrochloride acts as a precursor in taurine biosynthesis and component of coenzyme A. It is involved in the preparation of active pharmaceutical ingredients like ranitidine and nizatidine. It acts as an antidote for acetaminophen poisoning. Further, it is used in the oral treatment of nephropathic cystinosis, radiation sickness and disorders of cysteine excretion. In addition to this, it serves as an antioxidant and an inhibitor of 7,12-Dimethylbenz[a]anthracene (DMBA)-induced tumors. General Description Cysteamine is an aminothiol that can reduce important oxidized disulfide molecules such as cystine to yield cysteine. Hazard Toxic by inhalation and ingestion. Biochem/physiol Actions Cysteamine is an aminothiol that can reduce important oxidized disulfide molecules such as cystine to yield cysteine. Cysteamine is used in a wide range of applications from regulation of gene expression, to depletion of somatostatin, to coating of nanoparticles. Purification Methods Purify the salt by recrystallisation from EtOH. It is freely soluble in H2O and should be stored in a dry atmosphere. [Mills & Bogert J Am Chem Soc 62 1177 1940.] The picrate has m 125-126o; see previous entry for free base. [Beilstein 4 IV 1570.]   Cysteamine hydrochloride Preparation Products And Raw materials Raw materials Hydrochloric acid-->Sulfuric acid-->Carbon disulfide-->Ethanolamine Preparation Products 1,3-THIAZOLIDIN-2-ONE-->2-AMINOETHYLMETHYLSULFONE HYDROCHLORIDE-->THIAZOLIDINE-->Cystamine dihydrochloride-->N-(2-MERCAPTOETHYL)ACETAMIDE-->Thiazolidine, hydrochloride (1:1)-->2-METHYLTHIAZOLIDINE