China Largest Manufacturer factory sales Indole-6-carboxylic acid CAS 1670-82-2 CAS NO.1670-82-2

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Indole-6-carboxylic acid Basic information Product Name: Indole-6-carboxylic acid Synonyms: 6-INDOLECARBOXYLIC ACID;Indole-6-carboxylic acid in stock Factory;6-CARBOXYINDOLE;4-CARBOXAMIDOBENZOIC ACID;1H-INDOLE-6-CARBOXYLIC ACID;LABOTEST-BB LT00441293;INDOLE-6-CARBOXYLIC ACID;RARECHEM AL BE 1265 CAS: 1670-82-2 MF: C9H7NO2 MW: 161.16 EINECS: 605-464-3 Product Categories: Heterocycle-Indole series;Heterocyclic Building Blocks;Simple Indoles;Building Blocks;C7 to C9;Chemical Synthesis;blocks;Carboxes;IndolesOxindoles;Indole;Carboxylic Acids;Pyrroles & Indoles;Building Blocks;Heterocyclic Building Blocks;Indole/indoline/oxindole;Indole and Indoline;Indoles and derivatives;Carboxylic Acids;Pyrroles & Indoles;Organic acids;Indoles Mol File: 1670-82-2.mol   Indole-6-carboxylic acid Chemical Properties Melting point  249-253 °C(lit.) Boiling point  287.44°C (rough estimate) density  1.2480 (rough estimate) refractive index  1.5050 (estimate) storage temp.  Keep in dark place,Sealed in dry,Room Temperature pka 4.44±0.30(Predicted) form  Powder color  Yellow-beige to orange-brown BRN  123991 CAS DataBase Reference 1670-82-2(CAS DataBase Reference)   Safety Information Hazard Codes  Xn,Xi Risk Statements  36/37/38-21/22-20/21/22-51-36-22 Safety Statements  22-24/25-37/39-26 WGK Germany  3 Hazard Note  Irritant HS Code  29339900 MSDS Information Provider Language SigmaAldrich English ACROS English ALFA English   Indole-6-carboxylic acid Usage And Synthesis Chemical Properties yellow-beige to orange-brown powder Uses • ;Reactant for preparation of D-glutamic acid-based inhibitors of E. coli MurD ligase1• ;Reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors2• ;Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway3• ;Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity4• ;Reactant for preparation of pyridinyl carboxylates via esterification with chlorohyd Uses Reactant for preparation of D-glutamic acid-based inhibitors of E. coli MurD ligase Reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors Reactant for preparation of amide conju Uses Reactant for preparation of D-glutamic acid-based inhibitors of E. coli MurD ligase Reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity Reactant for preparation of pyridinyl carboxylates via esterification with chlorohydroxypyridine as SARS-CoV 3CL proinhibitors Reactant for preparation of (indolecarbonyl)-D-phenylglycinamide amides as factor Xa inhibitors Synthesis Reference(s) Journal of Medicinal Chemistry, 35, p. 2419, 1992 DOI: 10.1021/jm00091a010   Indole-6-carboxylic acid Preparation Products And Raw materials Raw materials Sodium hydroxide-->Hydrochloric acid-->Methanol-->Tetrahydrofuran-->N,N-Dimethylformamide-->Palladium-->N,N-Dimethylformamide dimethyl acetal-->Pyrrolidine-->4-Methyl-3-nitrobenzoic acid Preparation Products AKOS B006681

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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Indole-6-carboxylic acid Basic information Product Name: Indole-6-carboxylic acid Synonyms: 6-INDOLECARBOXYLIC ACID;Indole-6-carboxylic acid in stock Factory;6-CARBOXYINDOLE;4-CARBOXAMIDOBENZOIC ACID;1H-INDOLE-6-CARBOXYLIC ACID;LABOTEST-BB LT00441293;INDOLE-6-CARBOXYLIC ACID;RARECHEM AL BE 1265 CAS: 1670-82-2 MF: C9H7NO2 MW: 161.16 EINECS: 605-464-3 Product Categories: Heterocycle-Indole series;Heterocyclic Building Blocks;Simple Indoles;Building Blocks;C7 to C9;Chemical Synthesis;blocks;Carboxes;IndolesOxindoles;Indole;Carboxylic Acids;Pyrroles & Indoles;Building Blocks;Heterocyclic Building Blocks;Indole/indoline/oxindole;Indole and Indoline;Indoles and derivatives;Carboxylic Acids;Pyrroles & Indoles;Organic acids;Indoles Mol File: 1670-82-2.mol   Indole-6-carboxylic acid Chemical Properties Melting point  249-253 °C(lit.) Boiling point  287.44°C (rough estimate) density  1.2480 (rough estimate) refractive index  1.5050 (estimate) storage temp.  Keep in dark place,Sealed in dry,Room Temperature pka 4.44±0.30(Predicted) form  Powder color  Yellow-beige to orange-brown BRN  123991 CAS DataBase Reference 1670-82-2(CAS DataBase Reference)   Safety Information Hazard Codes  Xn,Xi Risk Statements  36/37/38-21/22-20/21/22-51-36-22 Safety Statements  22-24/25-37/39-26 WGK Germany  3 Hazard Note  Irritant HS Code  29339900 MSDS Information Provider Language SigmaAldrich English ACROS English ALFA English   Indole-6-carboxylic acid Usage And Synthesis Chemical Properties yellow-beige to orange-brown powder Uses • ;Reactant for preparation of D-glutamic acid-based inhibitors of E. coli MurD ligase1• ;Reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors2• ;Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway3• ;Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity4• ;Reactant for preparation of pyridinyl carboxylates via esterification with chlorohyd Uses Reactant for preparation of D-glutamic acid-based inhibitors of E. coli MurD ligase Reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors Reactant for preparation of amide conju Uses Reactant for preparation of D-glutamic acid-based inhibitors of E. coli MurD ligase Reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity Reactant for preparation of pyridinyl carboxylates via esterification with chlorohydroxypyridine as SARS-CoV 3CL proinhibitors Reactant for preparation of (indolecarbonyl)-D-phenylglycinamide amides as factor Xa inhibitors Synthesis Reference(s) Journal of Medicinal Chemistry, 35, p. 2419, 1992 DOI: 10.1021/jm00091a010   Indole-6-carboxylic acid Preparation Products And Raw materials Raw materials Sodium hydroxide-->Hydrochloric acid-->Methanol-->Tetrahydrofuran-->N,N-Dimethylformamide-->Palladium-->N,N-Dimethylformamide dimethyl acetal-->Pyrrolidine-->4-Methyl-3-nitrobenzoic acid Preparation Products AKOS B006681