China Biggest Manufacturer factory sales L-Mandelic Acid CAS 17199-29-0 CAS NO.17199-29-0

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(S)-(+)-Mandelic acid Basic information Product Name: (S)-(+)-Mandelic acid Synonyms: (s)-(+)-mandelic;(s)-benzeneaceticaci;(S)-Hydroxyphenylaceticacid;Benzeneaceticacid,alpha-hydroxy-,(S)-;L-mandelate;(S)-(+)-MANDELIC ACID FOR RESOLUTION OF RACEMATES 99+%;L-(+)-Mandelic acid, 99+%;L-(+)-α-Hydroxybenzeneacetic acid CAS: 17199-29-0 MF: C8H8O3 MW: 152.15 EINECS: 241-240-8 Product Categories: Activators;Analytical Chemistry;Carboxylic Acids (Chiral);Chiral Building Blocks;e.e. / Absolute Configuration Determination (NMR);Enantiomer Excess & Absolute Configuration Determination;FINE Chemical & INTERMEDIATES;Chiral Compounds;Aromatic Phenylacetic Acids and Derivatives;chiral;for Resolution of Bases;Optical Resolution;Synthetic Organic Chemistry;Chiral Compound;Cosmetic Mol File: 17199-29-0.mol   (S)-(+)-Mandelic acid Chemical Properties Melting point  131-134 °C(lit.) alpha  155 º (c=2 , H2O) Boiling point  234.6°C (rough estimate) density  1.3410 refractive index  153.5 ° (C=1, H2O) Fp  >190°C storage temp.  Store below +30°C. solubility  Methanol (Slightly), Water (Sparingly, Heated) pka 3.41±0.25(Predicted) form  Crystalline Powder color  White to beige-brown PH 2.1 (60g/l, H2O, 20℃) optical activity [α]20/D +153±5°, c = 5% in H2O Water Solubility  100 g/L (25 ºC) Sensitive  Light Sensitive BRN  2208678 Stability: Stable, but light sensitive. Combustible. Incompatible with strong bases, strong oxidizing agents, strong reducing agents. CAS DataBase Reference 17199-29-0(CAS DataBase Reference) NIST Chemistry Reference Benzeneacetic acid, «alpha»-hydroxy-, (s)-(17199-29-0) EPA Substance Registry System Benzeneacetic acid, .alpha.-hydroxy-, (.alpha.S)- (17199-29-0)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  22-24/25-37/39-26-36 WGK Germany  3 TSCA  Yes HS Code  29181980 MSDS Information Provider Language D-2-Hydroxy-2-phenylacetic acid English ACROS English SigmaAldrich English ALFA English   (S)-(+)-Mandelic acid Usage And Synthesis Chemical Properties white to light yellow crystal powde Uses Antiseptic (urinary). Uses (S)-(+)-Mandelic acid is a versatile reagent used in the resolution of racemates and the preparation of amides, Pharmaceutical Intermediates. Uses A versatile reagent used in the resolution of racemates and the preparation of amides. Purification Methods Purify the mandelic acids by recrystallisation from H2O, *C6H6 or CHCl3. [Roger J Chem Soc 2168 1932,Jamison & Turner J Chem Soc 611 1942.] They have solubilities in H2O of ca 11% at 25o. [Banks & Davies J Chem Soc 73 1938.] The S-benzylisothiuronium salts has m 180o (from H2O) and [] D 25 (+) and (-) 57o (c20, EtOH) [El Masri et al. Biochem J 68 199 1958]. [Beilstein 10 IV 564.]   (S)-(+)-Mandelic acid Preparation Products And Raw materials Preparation Products (3S)-(-)-3-(DIMETHYLAMINO)PYRROLIDINE-->(S)-(+)-alpha-Methoxyphenylacetic acid-->1H-Azepine-4-carboxylicacid,hexahydro-,methylester,(4S)-(9CI)-->(S)-(+)-Methyl mandelate-->(S)-(-)-2-HYDROXY-1,2,2-TRIPHENYLETHYL ACETATE-->2-Bromo-2-phenylacetic acid-->(S)-(+)-O-Acetyl-L-mandelic acid

                                      Group profiles

Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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                                                       Product information

(S)-(+)-Mandelic acid Basic information Product Name: (S)-(+)-Mandelic acid Synonyms: (s)-(+)-mandelic;(s)-benzeneaceticaci;(S)-Hydroxyphenylaceticacid;Benzeneaceticacid,alpha-hydroxy-,(S)-;L-mandelate;(S)-(+)-MANDELIC ACID FOR RESOLUTION OF RACEMATES 99+%;L-(+)-Mandelic acid, 99+%;L-(+)-α-Hydroxybenzeneacetic acid CAS: 17199-29-0 MF: C8H8O3 MW: 152.15 EINECS: 241-240-8 Product Categories: Activators;Analytical Chemistry;Carboxylic Acids (Chiral);Chiral Building Blocks;e.e. / Absolute Configuration Determination (NMR);Enantiomer Excess & Absolute Configuration Determination;FINE Chemical & INTERMEDIATES;Chiral Compounds;Aromatic Phenylacetic Acids and Derivatives;chiral;for Resolution of Bases;Optical Resolution;Synthetic Organic Chemistry;Chiral Compound;Cosmetic Mol File: 17199-29-0.mol   (S)-(+)-Mandelic acid Chemical Properties Melting point  131-134 °C(lit.) alpha  155 º (c=2 , H2O) Boiling point  234.6°C (rough estimate) density  1.3410 refractive index  153.5 ° (C=1, H2O) Fp  >190°C storage temp.  Store below +30°C. solubility  Methanol (Slightly), Water (Sparingly, Heated) pka 3.41±0.25(Predicted) form  Crystalline Powder color  White to beige-brown PH 2.1 (60g/l, H2O, 20℃) optical activity [α]20/D +153±5°, c = 5% in H2O Water Solubility  100 g/L (25 ºC) Sensitive  Light Sensitive BRN  2208678 Stability: Stable, but light sensitive. Combustible. Incompatible with strong bases, strong oxidizing agents, strong reducing agents. CAS DataBase Reference 17199-29-0(CAS DataBase Reference) NIST Chemistry Reference Benzeneacetic acid, «alpha»-hydroxy-, (s)-(17199-29-0) EPA Substance Registry System Benzeneacetic acid, .alpha.-hydroxy-, (.alpha.S)- (17199-29-0)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  22-24/25-37/39-26-36 WGK Germany  3 TSCA  Yes HS Code  29181980 MSDS Information Provider Language D-2-Hydroxy-2-phenylacetic acid English ACROS English SigmaAldrich English ALFA English   (S)-(+)-Mandelic acid Usage And Synthesis Chemical Properties white to light yellow crystal powde Uses Antiseptic (urinary). Uses (S)-(+)-Mandelic acid is a versatile reagent used in the resolution of racemates and the preparation of amides, Pharmaceutical Intermediates. Uses A versatile reagent used in the resolution of racemates and the preparation of amides. Purification Methods Purify the mandelic acids by recrystallisation from H2O, *C6H6 or CHCl3. [Roger J Chem Soc 2168 1932,Jamison & Turner J Chem Soc 611 1942.] They have solubilities in H2O of ca 11% at 25o. [Banks & Davies J Chem Soc 73 1938.] The S-benzylisothiuronium salts has m 180o (from H2O) and [] D 25 (+) and (-) 57o (c20, EtOH) [El Masri et al. Biochem J 68 199 1958]. [Beilstein 10 IV 564.]   (S)-(+)-Mandelic acid Preparation Products And Raw materials Preparation Products (3S)-(-)-3-(DIMETHYLAMINO)PYRROLIDINE-->(S)-(+)-alpha-Methoxyphenylacetic acid-->1H-Azepine-4-carboxylicacid,hexahydro-,methylester,(4S)-(9CI)-->(S)-(+)-Methyl mandelate-->(S)-(-)-2-HYDROXY-1,2,2-TRIPHENYLETHYL ACETATE-->2-Bromo-2-phenylacetic acid-->(S)-(+)-O-Acetyl-L-mandelic acid