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Home > Products >  China Biggest Factory & Manufacturer supply 3,3'-Diindolylmethane (DIM) 200MT/Year

China Biggest Factory & Manufacturer supply 3,3'-Diindolylmethane (DIM) 200MT/Year CAS NO.1968-05-4

  • FOB Price: USD: 1.00-2.00 /Kilogram Get Latest Price
  • Min.Order: 500 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,MoneyGram,Other
  • Available Specifications:

    AAAAA(50-100)KilogramAAAAA(100-500)Kilogram

  • Product Details

Keywords

  • 3,3'-Diindolylmethane
  • 1968-05-4
  • 1968-05-4

Quick Details

  • ProName: China Biggest Factory & Manufacturer s...
  • CasNo: 1968-05-4
  • Molecular Formula: 1968-05-4
  • Appearance: white powder
  • Application: chemicals industry
  • DeliveryTime: 3-5 days
  • PackAge: 25KG/Drum
  • Port: Shanghai Guangzhou Qingdao Shenzhen
  • ProductionCapacity: 200 Metric Ton/Month
  • Purity: 99%
  • Storage: 2-8°C
  • Transportation: By air /Sea/ coruier
  • LimitNum: 500 Kilogram
  • Color: white
  • Melting point: ≥350°C
  • Boiling point: 363.24°C (rough estimate)
  • density: 1.667
  • solubility: 1 M NaOH: 10 mg/mL, dark green
  • Water Solubility: <0.1 g/100 mL at 21 oC
  • Stability: Stable. Combustible. Incompatible with...

Superiority

3,3'-Diindolylmethane Basic information
Product Name: 3,3'-Diindolylmethane
Synonyms: 3,3'-Diindolylmethane(DIM);Di(1H-indol-3-yl);Plant Indole;3,3'-DIINDOLYLMETHANE, >=98% (HPLC);3,3'-METHYLENEBIS-1H-INDOLE;3,3'-METHYLENEBISINDOLE;3,3'-METHYLENEDIINDOLE;3,3'-DIINDOLYLMETHANE
CAS: 1968-05-4
MF: C17H14N2
MW: 246.31
EINECS: 100-201-5
Product Categories: Inhibitors;Pharmaceutical intermediates;Gene Regulation;Gene Regulation and Expression;Alkaloid;Antitumor Agents;Aromatic Compounds;Building Blocks;C13 to C27;Cancer Research;Cell Biology;Cell Signaling and Neuroscience;Chemical Synthesis;Enzyme Inhibitors;Indoles and derivatives;IndoleDerivative;Indoline & Oxindole;Indoles;Simple Indoles;Heterocyclic Building Blocks;Nutrition Research;Phytochemicals by Chemical Classification
Mol File: 1968-05-4.mol
3,3'-Diindolylmethane Structure
 
3,3'-Diindolylmethane Chemical Properties
Melting point  167 °C
Boiling point  230 °C(Press: 0.01 Torr)
density  1.271±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  Chloroform (Sparingly), Methanol (Slightly)
pka 16.91±0.30(Predicted)
form  Off-white powder.
CAS DataBase Reference 1968-05-4(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-26
WGK Germany  3
RTECS  NM0332000
HazardClass  IRRITANT
HS Code  29349990
MSDS Information
 
3,3'-Diindolylmethane Usage And Synthesis
Chemical Properties Solid
Uses apoptosis inducer
Uses An antineoplastic agent that activates Chk 2 and cytochrome p450
Uses

3,3′-Diindolylmethane may be used as a model substrate to analyze the role of 3,3′-diindolylmethane in inducing apoptosis in human cancer cells.

General Description

3,3′-Diindolylmethane, a dimer of indole-3-carbinol, is a component of cruciferous vegetables. It is known to exhibit anticancer effects.

Biochem/physiol Actions Acid-catalyzed reaction product of a phytochemical naturally found in Brassicaceae, indole-3-carbinol. It functions as an antitumor agent. This derivative can both directly stimulate apoptosis at relatively high concentrations and sensitize TRAIL-induced apoptosis in human cancer cells. DIM induces a G1 cell cycle arrest in human breast cancer MCF-7 cells by a mechanism that includes increased expression of p21. DIM is a strong mitochondrial H+-ATPase inhibitor. The function of DIM and its derivatives as a new plant growth promoter has been studied in an eco-friendly system.
 
3,3'-Diindolylmethane Preparation Products And Raw materials
Preparation Products 5,11-dihydro-5-phenylindolo[3,2-b]carbazole
 

Details

3,3'-Diindolylmethane Basic information
Product Name: 3,3'-Diindolylmethane
Synonyms: 3,3'-Diindolylmethane(DIM);Di(1H-indol-3-yl);Plant Indole;3,3'-DIINDOLYLMETHANE, >=98% (HPLC);3,3'-METHYLENEBIS-1H-INDOLE;3,3'-METHYLENEBISINDOLE;3,3'-METHYLENEDIINDOLE;3,3'-DIINDOLYLMETHANE
CAS: 1968-05-4
MF: C17H14N2
MW: 246.31
EINECS: 100-201-5
Product Categories: Inhibitors;Pharmaceutical intermediates;Gene Regulation;Gene Regulation and Expression;Alkaloid;Antitumor Agents;Aromatic Compounds;Building Blocks;C13 to C27;Cancer Research;Cell Biology;Cell Signaling and Neuroscience;Chemical Synthesis;Enzyme Inhibitors;Indoles and derivatives;IndoleDerivative;Indoline & Oxindole;Indoles;Simple Indoles;Heterocyclic Building Blocks;Nutrition Research;Phytochemicals by Chemical Classification
Mol File: 1968-05-4.mol
3,3'-Diindolylmethane Structure
 
3,3'-Diindolylmethane Chemical Properties
Melting point  167 °C
Boiling point  230 °C(Press: 0.01 Torr)
density  1.271±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  Chloroform (Sparingly), Methanol (Slightly)
pka 16.91±0.30(Predicted)
form  Off-white powder.
CAS DataBase Reference 1968-05-4(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-26
WGK Germany  3
RTECS  NM0332000
HazardClass  IRRITANT
HS Code  29349990
MSDS Information
 
3,3'-Diindolylmethane Usage And Synthesis
Chemical Properties Solid
Uses apoptosis inducer
Uses An antineoplastic agent that activates Chk 2 and cytochrome p450
Uses

3,3′-Diindolylmethane may be used as a model substrate to analyze the role of 3,3′-diindolylmethane in inducing apoptosis in human cancer cells.

General Description

3,3′-Diindolylmethane, a dimer of indole-3-carbinol, is a component of cruciferous vegetables. It is known to exhibit anticancer effects.

Biochem/physiol Actions Acid-catalyzed reaction product of a phytochemical naturally found in Brassicaceae, indole-3-carbinol. It functions as an antitumor agent. This derivative can both directly stimulate apoptosis at relatively high concentrations and sensitize TRAIL-induced apoptosis in human cancer cells. DIM induces a G1 cell cycle arrest in human breast cancer MCF-7 cells by a mechanism that includes increased expression of p21. DIM is a strong mitochondrial H+-ATPase inhibitor. The function of DIM and its derivatives as a new plant growth promoter has been studied in an eco-friendly system.
 
3,3'-Diindolylmethane Preparation Products And Raw materials
Preparation Products 5,11-dihydro-5-phenylindolo[3,2-b]carbazole

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