China Biggest Factory manufacturer supply 3,3'-Diindolylmethane (DIM) CAS NO.1968-05-4

                                PRODUCT DETAILS                           

3,3'-Diindolylmethane Basic information Product Name: 3,3'-Diindolylmethane Synonyms: 3,3'-Diindolylmethane(DIM);Di(1H-indol-3-yl);Plant Indole;3,3'-DIINDOLYLMETHANE, >=98% (HPLC);3,3'-METHYLENEBIS-1H-INDOLE;3,3'-METHYLENEBISINDOLE;3,3'-METHYLENEDIINDOLE;3,3'-DIINDOLYLMETHANE CAS: 1968-05-4 MF: C17H14N2 MW: 246.31 EINECS: 100-201-5 Product Categories: Inhibitors;Pharmaceutical intermediates;Gene Regulation;Gene Regulation and Expression;Alkaloid;Antitumor Agents;Aromatic Compounds;Building Blocks;C13 to C27;Cancer Research;Cell Biology;Cell Signaling and Neuroscience;Chemical Synthesis;Enzyme Inhibitors;Indoles and derivatives;IndoleDerivative;Indoline & Oxindole;Indoles;Simple Indoles;Heterocyclic Building Blocks;Nutrition Research;Phytochemicals by Chemical Classification Mol File: 1968-05-4.mol   3,3'-Diindolylmethane Chemical Properties Melting point  167 °C Boiling point  230 °C(Press: 0.01 Torr) density  1.271±0.06 g/cm3(Predicted) storage temp.  2-8°C solubility  Chloroform (Sparingly), Methanol (Slightly) pka 16.91±0.30(Predicted) form  Off-white powder. color  White to Pale Beige CAS DataBase Reference 1968-05-4(CAS DataBase Reference)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  22-24/25-26 WGK Germany  3 RTECS  NM0332000 HazardClass  IRRITANT HS Code  29349990 MSDS Information   3,3'-Diindolylmethane Usage And Synthesis Chemical Properties Solid Uses apoptosis inducer Uses An antineoplastic agent that activates Chk 2 and cytochrome p450 Uses 3,3′-Diindolylmethane may be used as a model substrate to analyze the role of 3,3′-diindolylmethane in inducing apoptosis in human cancer cells. General Description 3,3′-Diindolylmethane, a dimer of indole-3-carbinol, is a component of cruciferous vegetables. It is known to exhibit anticancer effects. Biochem/physiol Actions Acid-catalyzed reaction product of a phytochemical naturally found in Brassicaceae, indole-3-carbinol. It functions as an antitumor agent. This derivative can both directly stimulate apoptosis at relatively high concentrations and sensitize TRAIL-induced apoptosis in human cancer cells. DIM induces a G1 cell cycle arrest in human breast cancer MCF-7 cells by a mechanism that includes increased expression of p21. DIM is a strong mitochondrial H+-ATPase inhibitor. The function of DIM and its derivatives as a new plant growth promoter has been studied in an eco-friendly system.   3,3'-Diindolylmethane Preparation Products And Raw materials Preparation Products 5,11-dihydro-5-phenylindolo[3,2-b]carbazole

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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                                                       Product information

3,3'-Diindolylmethane Basic information Product Name: 3,3'-Diindolylmethane Synonyms: 3,3'-Diindolylmethane(DIM);Di(1H-indol-3-yl);Plant Indole;3,3'-DIINDOLYLMETHANE, >=98% (HPLC);3,3'-METHYLENEBIS-1H-INDOLE;3,3'-METHYLENEBISINDOLE;3,3'-METHYLENEDIINDOLE;3,3'-DIINDOLYLMETHANE CAS: 1968-05-4 MF: C17H14N2 MW: 246.31 EINECS: 100-201-5 Product Categories: Inhibitors;Pharmaceutical intermediates;Gene Regulation;Gene Regulation and Expression;Alkaloid;Antitumor Agents;Aromatic Compounds;Building Blocks;C13 to C27;Cancer Research;Cell Biology;Cell Signaling and Neuroscience;Chemical Synthesis;Enzyme Inhibitors;Indoles and derivatives;IndoleDerivative;Indoline & Oxindole;Indoles;Simple Indoles;Heterocyclic Building Blocks;Nutrition Research;Phytochemicals by Chemical Classification Mol File: 1968-05-4.mol   3,3'-Diindolylmethane Chemical Properties Melting point  167 °C Boiling point  230 °C(Press: 0.01 Torr) density  1.271±0.06 g/cm3(Predicted) storage temp.  2-8°C solubility  Chloroform (Sparingly), Methanol (Slightly) pka 16.91±0.30(Predicted) form  Off-white powder. color  White to Pale Beige CAS DataBase Reference 1968-05-4(CAS DataBase Reference)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  22-24/25-26 WGK Germany  3 RTECS  NM0332000 HazardClass  IRRITANT HS Code  29349990 MSDS Information   3,3'-Diindolylmethane Usage And Synthesis Chemical Properties Solid Uses apoptosis inducer Uses An antineoplastic agent that activates Chk 2 and cytochrome p450 Uses 3,3′-Diindolylmethane may be used as a model substrate to analyze the role of 3,3′-diindolylmethane in inducing apoptosis in human cancer cells. General Description 3,3′-Diindolylmethane, a dimer of indole-3-carbinol, is a component of cruciferous vegetables. It is known to exhibit anticancer effects. Biochem/physiol Actions Acid-catalyzed reaction product of a phytochemical naturally found in Brassicaceae, indole-3-carbinol. It functions as an antitumor agent. This derivative can both directly stimulate apoptosis at relatively high concentrations and sensitize TRAIL-induced apoptosis in human cancer cells. DIM induces a G1 cell cycle arrest in human breast cancer MCF-7 cells by a mechanism that includes increased expression of p21. DIM is a strong mitochondrial H+-ATPase inhibitor. The function of DIM and its derivatives as a new plant growth promoter has been studied in an eco-friendly system.   3,3'-Diindolylmethane Preparation Products And Raw materials Preparation Products 5,11-dihydro-5-phenylindolo[3,2-b]carbazole