China Original Largest Manufacturer sales 6-Chloropurine Riboside CAS 2004-06-0 CAS NO.2004-06-0

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6-Chloropurine ribonucleoside Basic information Product Name: 6-Chloropurine ribonucleoside Synonyms: 6-chloropurineribonucleoside;6-CLPR;6-CHLORO-9-(BETA-D-RIBOFURANOSYL)PURINE;6-CHLOROINOSINE;6-CHLOROPURINE-9-RIBOSIDE;6-CHLOROPURINE NUCLEOSIDE;6-chloro-9-ribofuranosyl-9H-purine;6-Chloropurine riboside, pure, 99+% CAS: 2004-06-0 MF: C10H11ClN4O4 MW: 286.67 EINECS: 217-904-8 Product Categories: chiral;Biochemistry;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents Mol File: 2004-06-0.mol   6-Chloropurine ribonucleoside Chemical Properties Melting point  158-162 °C (dec.)(lit.) Boiling point  614.8±65.0 °C(Predicted) density  1.7303 (rough estimate) refractive index  -45 ° (C=0.8, H2O) storage temp.  Sealed in dry,Store in freezer, under -20°C form  Powder pka 13.06±0.70(Predicted) color  Yellow to Green CAS DataBase Reference 2004-06-0(CAS DataBase Reference)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  22-24/25-36-26 RTECS  UO7520800 F  10-23 Hazard Note  Irritant HS Code  29389090 MSDS Information Provider Language 6-Chloropurine riboside English SigmaAldrich English ACROS English   6-Chloropurine ribonucleoside Usage And Synthesis Chemical Properties white to light yellow crystal powde Uses 6-CHLOROPURINE RIBOSIDE acts as a reactant in the synthesis of isozyme-specific enzyme inhibitors as well as in the preparation of dog coronary artery receptor agonists. Purification Methods Purify the riboside by suspending the dry solid (~12 g) in hot MeOH (130 mL) and then adding enough hot H2O (~560mL) to cause solution, filter and set aside at 5o overnight. The colourless crystals of the riboside are filtered off, washed with Me2CO, Et2O and dried at 60o/0.1mm. More material can be obtained by evaporating the filtrate to dryness and recrystallisation of the residue from MeOH/H2O (2:1) (15mL/g). It has max 264nm ( 9140) in H2O. [Robins Biochemical Preparations 10 145 1963, Baker et al. J Org Chem 22 954 1957.]   6-Chloropurine ribonucleoside Preparation Products And Raw materials Raw materials [3,4-dibenzoyloxy-5-(6-chloropurin-9-yl)oxolan-2-yl]methyl benzoate-->2,3,5-TRI-O-ACETYL-6-CHLOROPURINE-9--D-RIBOFURANOSIDE-->TETRAACETYLRIBOFURANOSE-->1-O-ACETYL-2,3,5-TRI-O-BENZOYL-D-RIBOFURANOSE-->ACETIC ACID (2R,3R,4R,5R)-3,4-DIACETOXY-5-(2-AMINO-6-CHLORO-PURIN-9-YL)-TETRAHYDRO-FURAN-2-YLMETHYL ESTER-->2',3',5'-TRI-O-ACETYLINOSINE-->Uridine-->Inosine-->6-Chloropurine Preparation Products 2-(6-ethylaminopurin-9-yl)-5-(hydroxymethyl)oxol-->N6-CYCLOHEXYLADENOSINE-->S-(4-NITROBENZYL)-6-THIOINOSINE

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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6-Chloropurine ribonucleoside Basic information Product Name: 6-Chloropurine ribonucleoside Synonyms: 6-chloropurineribonucleoside;6-CLPR;6-CHLORO-9-(BETA-D-RIBOFURANOSYL)PURINE;6-CHLOROINOSINE;6-CHLOROPURINE-9-RIBOSIDE;6-CHLOROPURINE NUCLEOSIDE;6-chloro-9-ribofuranosyl-9H-purine;6-Chloropurine riboside, pure, 99+% CAS: 2004-06-0 MF: C10H11ClN4O4 MW: 286.67 EINECS: 217-904-8 Product Categories: chiral;Biochemistry;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents Mol File: 2004-06-0.mol   6-Chloropurine ribonucleoside Chemical Properties Melting point  158-162 °C (dec.)(lit.) Boiling point  614.8±65.0 °C(Predicted) density  1.7303 (rough estimate) refractive index  -45 ° (C=0.8, H2O) storage temp.  Sealed in dry,Store in freezer, under -20°C form  Powder pka 13.06±0.70(Predicted) color  Yellow to Green CAS DataBase Reference 2004-06-0(CAS DataBase Reference)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  22-24/25-36-26 RTECS  UO7520800 F  10-23 Hazard Note  Irritant HS Code  29389090 MSDS Information Provider Language 6-Chloropurine riboside English SigmaAldrich English ACROS English   6-Chloropurine ribonucleoside Usage And Synthesis Chemical Properties white to light yellow crystal powde Uses 6-CHLOROPURINE RIBOSIDE acts as a reactant in the synthesis of isozyme-specific enzyme inhibitors as well as in the preparation of dog coronary artery receptor agonists. Purification Methods Purify the riboside by suspending the dry solid (~12 g) in hot MeOH (130 mL) and then adding enough hot H2O (~560mL) to cause solution, filter and set aside at 5o overnight. The colourless crystals of the riboside are filtered off, washed with Me2CO, Et2O and dried at 60o/0.1mm. More material can be obtained by evaporating the filtrate to dryness and recrystallisation of the residue from MeOH/H2O (2:1) (15mL/g). It has max 264nm ( 9140) in H2O. [Robins Biochemical Preparations 10 145 1963, Baker et al. J Org Chem 22 954 1957.]   6-Chloropurine ribonucleoside Preparation Products And Raw materials Raw materials [3,4-dibenzoyloxy-5-(6-chloropurin-9-yl)oxolan-2-yl]methyl benzoate-->2,3,5-TRI-O-ACETYL-6-CHLOROPURINE-9--D-RIBOFURANOSIDE-->TETRAACETYLRIBOFURANOSE-->1-O-ACETYL-2,3,5-TRI-O-BENZOYL-D-RIBOFURANOSE-->ACETIC ACID (2R,3R,4R,5R)-3,4-DIACETOXY-5-(2-AMINO-6-CHLORO-PURIN-9-YL)-TETRAHYDRO-FURAN-2-YLMETHYL ESTER-->2',3',5'-TRI-O-ACETYLINOSINE-->Uridine-->Inosine-->6-Chloropurine Preparation Products 2-(6-ethylaminopurin-9-yl)-5-(hydroxymethyl)oxol-->N6-CYCLOHEXYLADENOSINE-->S-(4-NITROBENZYL)-6-THIOINOSINE