China Biggest Manufacturer factory sales 1-Acetylimidazole CAS 2466-76-4 CAS NO.2466-76-4

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1-Acetylimidazole Basic information Product Name: 1-Acetylimidazole Synonyms: 1-Acetylimidazole98%;N-Acetylimidazole,98%;N-ACETYLIMIDAZOL;N-ACETYLIMIDAZOLE extrapure AR;1-Imidazolylmethyl ketone;1-Imidazol-1-ylethanone;1-(1H-Imidazole-1-yl)ethanone;1-Acetylimidazole ,99% CAS: 2466-76-4 MF: C5H6N2O MW: 110.11 EINECS: 219-577-7 Product Categories: amino;ImidazolesProtein Modification;Reagents for tyrosine modification;Building Blocks;Heterocyclic Building Blocks;Specific Amino Acid Modification;Imidazoles;Acylation (GC Derivatizing Reagents);GC Derivatizing Reagents;Analytical Chemistry Mol File: 2466-76-4.mol   1-Acetylimidazole Chemical Properties Melting point  99-105 °C (lit.) Boiling point  206.4°C (rough estimate) density  1.2111 (rough estimate) refractive index  1.4800 (estimate) storage temp.  2-8°C solubility  water: soluble50mg/mL, clear, colorless pka pKa 3.6(H2O,t = 25,I=0.2) (Uncertain) form  Adhering Crystals or Crystalline Powder color  White to beige or light tan Water Solubility  Hydrolyzes in water. Solubility in methanol (almost transparency). Sensitive  Moisture Sensitive BRN  108425 Stability: Moisture Sensitive CAS DataBase Reference 2466-76-4(CAS DataBase Reference) NIST Chemistry Reference 1H-Imidazole, 1-acetyl-(2466-76-4) EPA Substance Registry System 1H-Imidazole, 1-acetyl- (2466-76-4)   Safety Information Risk Statements  36/37/38 Safety Statements  24/25 WGK Germany  3 RTECS  NI3400000 F  10-21 TSCA  Yes HS Code  29332900 MSDS Information Provider Language NAI English ACROS English SigmaAldrich English ALFA English   1-Acetylimidazole Usage And Synthesis Chemical Properties white to beige or light tan adhering crystals or Uses Acetylating agent for capping unreacted amino groups in peptide synthesis. Uses It is a mild acylating agent and its reactivity can be enhanced by quaternization with, e.g. benzyl bromide. 1-Acetylimidazole was used as acetylation reagent for amino groups. It was also employed for acetylation of histones. It is relatively specific reagent for tyrosyl residue acetylatioa dn a reagent used in the synthesis of annulated imidazole derivatives. Uses Relatively specific reagent for tyrosyl residue acetylation. Reagent used in the synthesis of annulated imidazole derivatives. General Description Rate of solvolysis of 1-acetylimidazole in acid solutions was evaluated. Reaction of 1-acetylimidazole with orthophosphate and adenosine-5′-phosphate has been reported. Purification Methods It is recrystallised from isopropenyl acetate and dried in a vacuum over P2O5. [Riordan & Valee Methods Enzymol 25 500 1972, Beilstein 23/4 V 218.]   1-Acetylimidazole Preparation Products And Raw materials Raw materials Isopropenyl acetate Preparation Products 1-(1H-IMIDAZOL-2-YL)-ETHANONE HCL-->2',3',5'-Tri-O-acetyl-D-adenosine-->Ganciclovir Mono-O-acetate-->(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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1-Acetylimidazole Basic information Product Name: 1-Acetylimidazole Synonyms: 1-Acetylimidazole98%;N-Acetylimidazole,98%;N-ACETYLIMIDAZOL;N-ACETYLIMIDAZOLE extrapure AR;1-Imidazolylmethyl ketone;1-Imidazol-1-ylethanone;1-(1H-Imidazole-1-yl)ethanone;1-Acetylimidazole ,99% CAS: 2466-76-4 MF: C5H6N2O MW: 110.11 EINECS: 219-577-7 Product Categories: amino;ImidazolesProtein Modification;Reagents for tyrosine modification;Building Blocks;Heterocyclic Building Blocks;Specific Amino Acid Modification;Imidazoles;Acylation (GC Derivatizing Reagents);GC Derivatizing Reagents;Analytical Chemistry Mol File: 2466-76-4.mol   1-Acetylimidazole Chemical Properties Melting point  99-105 °C (lit.) Boiling point  206.4°C (rough estimate) density  1.2111 (rough estimate) refractive index  1.4800 (estimate) storage temp.  2-8°C solubility  water: soluble50mg/mL, clear, colorless pka pKa 3.6(H2O,t = 25,I=0.2) (Uncertain) form  Adhering Crystals or Crystalline Powder color  White to beige or light tan Water Solubility  Hydrolyzes in water. Solubility in methanol (almost transparency). Sensitive  Moisture Sensitive BRN  108425 Stability: Moisture Sensitive CAS DataBase Reference 2466-76-4(CAS DataBase Reference) NIST Chemistry Reference 1H-Imidazole, 1-acetyl-(2466-76-4) EPA Substance Registry System 1H-Imidazole, 1-acetyl- (2466-76-4)   Safety Information Risk Statements  36/37/38 Safety Statements  24/25 WGK Germany  3 RTECS  NI3400000 F  10-21 TSCA  Yes HS Code  29332900 MSDS Information Provider Language NAI English ACROS English SigmaAldrich English ALFA English   1-Acetylimidazole Usage And Synthesis Chemical Properties white to beige or light tan adhering crystals or Uses Acetylating agent for capping unreacted amino groups in peptide synthesis. Uses It is a mild acylating agent and its reactivity can be enhanced by quaternization with, e.g. benzyl bromide. 1-Acetylimidazole was used as acetylation reagent for amino groups. It was also employed for acetylation of histones. It is relatively specific reagent for tyrosyl residue acetylatioa dn a reagent used in the synthesis of annulated imidazole derivatives. Uses Relatively specific reagent for tyrosyl residue acetylation. Reagent used in the synthesis of annulated imidazole derivatives. General Description Rate of solvolysis of 1-acetylimidazole in acid solutions was evaluated. Reaction of 1-acetylimidazole with orthophosphate and adenosine-5′-phosphate has been reported. Purification Methods It is recrystallised from isopropenyl acetate and dried in a vacuum over P2O5. [Riordan & Valee Methods Enzymol 25 500 1972, Beilstein 23/4 V 218.]   1-Acetylimidazole Preparation Products And Raw materials Raw materials Isopropenyl acetate Preparation Products 1-(1H-IMIDAZOL-2-YL)-ETHANONE HCL-->2',3',5'-Tri-O-acetyl-D-adenosine-->Ganciclovir Mono-O-acetate-->(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane