China Largest Factory Manufacturer Supply Antioxidant 168 CAS 31570-04-4 CAS NO.31570-04-4

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Antioxidant 168 Basic information Characterization Reactions Applications Features/benefits Guidelines for use Physical Properties Safety Product Name: Antioxidant 168 Synonyms: Phenol,2,4-bis(1,1-dimethylethyl,phosphite(3:1);tri(2,4-Ditertrabutylphenyl)phosphiteester;Tris(2,4-di-tert-butylphenyl)phoshit;Doverphos-S-480;Phosphorous acid tri(2,4-di-tert-butylphenyl) ester;Phosphorous acid tris[2,4-bis(tert-butyl)phenyl] ester;Tris(2,4-di-tert-butylphenyloxy)phosphine;4-di-tert-butylphenyl)phosphite CAS: 31570-04-4 MF: C42H63O3P MW: 646.94 EINECS: 250-709-6 Product Categories: Achiral Phosphine;Aryl Phosphine;Additives for Plastic;organophosphorus compound;Polymer Additives;Polymer Science;Organics;Polymer Additives;Polymer Science;Stabilizers Mol File: 31570-04-4.mol   Antioxidant 168 Chemical Properties Melting point  181-184 °C(lit.) Boiling point  594.2±50.0 °C(Predicted) density  -0.98 Fp  46°C (115°F) storage temp.  2-8°C solubility  Acetonitrile (Slightly), Chloroform (Sparingly), Ethyl Acetate (Sparingly, Heate form  Powder color  white Specific Gravity 0.98 Sensitive  moisture sensitive Hydrolytic Sensitivity 4: no reaction with water under neutral conditions Stability: Moisture Sensitive InChIKey JKIJEFPNVSHHEI-UHFFFAOYSA-N CAS DataBase Reference 31570-04-4(CAS DataBase Reference) EPA Substance Registry System Tris(2,4-di-tert-butylphenyl) phosphite (31570-04-4)   Safety Information WGK Germany  - TSCA  Yes HS Code  2920900002 MSDS Information Provider Language SigmaAldrich English   Antioxidant 168 Usage And Synthesis Characterization Antioxidant 168  is a hydrolytically stable phosphite processing stabilizer. As a secondary antioxidant,Antioxidant 168 reacts during processing with hydroperoxides formed by autoxidation of polymers preventing process induced degradation and extending the performance of primary antioxidants. Reactions Precursor to a palladacyclic catalyst for Suzuki, Stille and Heck processes. Ligand for Pd-catalyzed [3+2] intramolecular cycloaddition of alk-5-enylidenecyclopropanes. Ligand for Pt-catalyzed intramolecular silaboration of alkenes. Ligand for Ni-catalyzed aminocarbonylation of aryl halides. Ligand for the Au-catalyzed [4+2] intramolecular cycloaddition of allene-dienes. Rhodium-Catalyzed Allylic Substitution with an Acyl Anion Equivalent.  Applications The application range of Antioxidant 168 -synergistically combined with other Ciba anti-oxidants - comprises polyolefins and olefin-copolymers such as polyethylene (e.g. HDPE, LLDPE), polypropylene, polybutene and ethylene-vinylacetate copolymers as well as polycarbonates and polyamides. The blends can also be used in polyesters, styrene homo- and copolymers, adhesives and natural and synthetic tackifier resins, elastomers such as BR, SEBS, SBS, and other organic substrates. Antioxidant 168  blends can be used in combination with light stabilizers of the TINUVIN and CHIMASSORB range. Features/benefits Antioxidant 168  is an organophosphite of low volatility and is particularly resistant to hydrolysis. It protects polymers which are prone to oxidation, during the processing steps (compounding/ pelletizing, fabrication and recycling) from molecular weight change (e.g. chain scission/crosslinking) and prevents discoloration. Antioxidant 168 performs best when combined with other Ciba antioxidants. Blends of Antioxidant 168 with antioxidants of the IRGANOX range (IRGANOX B-blends) and with Hydroxylamine FS042 are particularly effective. The IRGANOX range antioxidants additionally provide storage stability and give the polymer long term protection against thermo-oxidative degradation. Antioxidant 168 comprised in phenol free systems with other appropriate Ciba stabilizers addresses specific stabilization requirements. Guidelines for use Typically 500 - 2000 ppm of Antioxidant 168 combined with appropriate levels of other additives are used for the processing stabilization of polymers. The optimum level is application specific. Extensive performance data of Antioxidant 168 combinations in various organic polymers and applications are available upon request. Physical Properties Safety In accordance with good industrial practice, handle with care and prevent contamination of the environment. Avoid dust formation and ignition sources. For more detailed information please refer to the material safety data sheet. Description ANTIOXIDANT 168  is a secondary antioxidant with excellent resistance to extraction by water, low volatility and high heat stability. It can effectively decompose hydroperoxides produced during the processing of polymeric materials. ANTIOXIDANT 168 usually not used alone, is compounded with hindered phenolic primary antioxidants such as 1010 to improve thermostability of polymer during the processing. There are over ten kinds of blends of 168 with phenolic antioxidants, widely use in the polymer materials such as PE, PP, PA, PC, ABS and so on. Uses Tris(2,4-tert-butylphenyl) Phosphite is an intermediate in the synthesis of Tris(2,4-di-tert-butylphenyl)phosphate (T884500), a processing stabilizer for polymers. Uses This product is an excellent Antioxidant wnameely applied to polyethylene, polypropylene, polyoxymethylene, ABS resin, PS resin, PVC, engineering plastics, binding agent, rubber, petroleum etc. for product polymerization. Application Antioxidant 168 is a kind of phosphite ester antioxidant as processing stabilizer, used for polypropylene, polyethylene, and adhesives. The amount to be used may be 0.1%~1.0% depending on the substrate, processing conditions, and requirements of the end application. Blends with hindered phenols are particularly effective.In addition, they use combination with light stabilizers when need. General Description Tris(2,4-di-tert-butylphenyl) phosphite is a triaryl based phosphite that can be used in catalysis and metallation. Its characteristic to undergo metallation reaction and provide a cost effective synthetic processes allows it to be useful in biaryl coupling reactions. Safety Antioxidant 168 is approved for indirect food contact applications. Properties and Applications TEST ITEMS SPECIFICATION APPEARANCE WHITE INCOMPACT POWDER CONTENT 99.0% min MELTING RANGE 183-187 °C VOLATILE 0.3% max SOLUBILITY 2g/20ml TOLUENE CLEAR FREE 2,4-DITERT-BUTYPHENOL 0.2% max (wt) TRANSMITTANCE 98% min 425nm 98% min 500nm ACID VALUE,mg KOH/g 0.3% max HYDROLYSIS TIME (90°C WATER ） 14 h min         SOLUBILITY 1% ACETONE 30% TOLUENE 36% CHLOROFORM 4% ETHYL ACETATE 11% n-HEXANE 0.1% ETHANOL 36% DICHLOROETHANE 6% max PHENYLETHYLENE 0.01% max WATER   Antioxidant 168 Preparation Products And Raw materials Raw materials Ethanol-->Xylene-->Phosphorus trichloride-->Phenol-->2,4-Di-tert-butylphenol Preparation Products Complex antioxidant

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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Antioxidant 168 Basic information Characterization Reactions Applications Features/benefits Guidelines for use Physical Properties Safety Product Name: Antioxidant 168 Synonyms: Phenol,2,4-bis(1,1-dimethylethyl,phosphite(3:1);tri(2,4-Ditertrabutylphenyl)phosphiteester;Tris(2,4-di-tert-butylphenyl)phoshit;Doverphos-S-480;Phosphorous acid tri(2,4-di-tert-butylphenyl) ester;Phosphorous acid tris[2,4-bis(tert-butyl)phenyl] ester;Tris(2,4-di-tert-butylphenyloxy)phosphine;4-di-tert-butylphenyl)phosphite CAS: 31570-04-4 MF: C42H63O3P MW: 646.94 EINECS: 250-709-6 Product Categories: Achiral Phosphine;Aryl Phosphine;Additives for Plastic;organophosphorus compound;Polymer Additives;Polymer Science;Organics;Polymer Additives;Polymer Science;Stabilizers Mol File: 31570-04-4.mol   Antioxidant 168 Chemical Properties Melting point  181-184 °C(lit.) Boiling point  594.2±50.0 °C(Predicted) density  -0.98 Fp  46°C (115°F) storage temp.  2-8°C solubility  Acetonitrile (Slightly), Chloroform (Sparingly), Ethyl Acetate (Sparingly, Heate form  Powder color  white Specific Gravity 0.98 Sensitive  moisture sensitive Hydrolytic Sensitivity 4: no reaction with water under neutral conditions Stability: Moisture Sensitive InChIKey JKIJEFPNVSHHEI-UHFFFAOYSA-N CAS DataBase Reference 31570-04-4(CAS DataBase Reference) EPA Substance Registry System Tris(2,4-di-tert-butylphenyl) phosphite (31570-04-4)   Safety Information WGK Germany  - TSCA  Yes HS Code  2920900002 MSDS Information Provider Language SigmaAldrich English   Antioxidant 168 Usage And Synthesis Characterization Antioxidant 168  is a hydrolytically stable phosphite processing stabilizer. As a secondary antioxidant,Antioxidant 168 reacts during processing with hydroperoxides formed by autoxidation of polymers preventing process induced degradation and extending the performance of primary antioxidants. Reactions Precursor to a palladacyclic catalyst for Suzuki, Stille and Heck processes. Ligand for Pd-catalyzed [3+2] intramolecular cycloaddition of alk-5-enylidenecyclopropanes. Ligand for Pt-catalyzed intramolecular silaboration of alkenes. Ligand for Ni-catalyzed aminocarbonylation of aryl halides. Ligand for the Au-catalyzed [4+2] intramolecular cycloaddition of allene-dienes. Rhodium-Catalyzed Allylic Substitution with an Acyl Anion Equivalent.  Applications The application range of Antioxidant 168 -synergistically combined with other Ciba anti-oxidants - comprises polyolefins and olefin-copolymers such as polyethylene (e.g. HDPE, LLDPE), polypropylene, polybutene and ethylene-vinylacetate copolymers as well as polycarbonates and polyamides. The blends can also be used in polyesters, styrene homo- and copolymers, adhesives and natural and synthetic tackifier resins, elastomers such as BR, SEBS, SBS, and other organic substrates. Antioxidant 168  blends can be used in combination with light stabilizers of the TINUVIN and CHIMASSORB range. Features/benefits Antioxidant 168  is an organophosphite of low volatility and is particularly resistant to hydrolysis. It protects polymers which are prone to oxidation, during the processing steps (compounding/ pelletizing, fabrication and recycling) from molecular weight change (e.g. chain scission/crosslinking) and prevents discoloration. Antioxidant 168 performs best when combined with other Ciba antioxidants. Blends of Antioxidant 168 with antioxidants of the IRGANOX range (IRGANOX B-blends) and with Hydroxylamine FS042 are particularly effective. The IRGANOX range antioxidants additionally provide storage stability and give the polymer long term protection against thermo-oxidative degradation. Antioxidant 168 comprised in phenol free systems with other appropriate Ciba stabilizers addresses specific stabilization requirements. Guidelines for use Typically 500 - 2000 ppm of Antioxidant 168 combined with appropriate levels of other additives are used for the processing stabilization of polymers. The optimum level is application specific. Extensive performance data of Antioxidant 168 combinations in various organic polymers and applications are available upon request. Physical Properties Safety In accordance with good industrial practice, handle with care and prevent contamination of the environment. Avoid dust formation and ignition sources. For more detailed information please refer to the material safety data sheet. Description ANTIOXIDANT 168  is a secondary antioxidant with excellent resistance to extraction by water, low volatility and high heat stability. It can effectively decompose hydroperoxides produced during the processing of polymeric materials. ANTIOXIDANT 168 usually not used alone, is compounded with hindered phenolic primary antioxidants such as 1010 to improve thermostability of polymer during the processing. There are over ten kinds of blends of 168 with phenolic antioxidants, widely use in the polymer materials such as PE, PP, PA, PC, ABS and so on. Uses Tris(2,4-tert-butylphenyl) Phosphite is an intermediate in the synthesis of Tris(2,4-di-tert-butylphenyl)phosphate (T884500), a processing stabilizer for polymers. Uses This product is an excellent Antioxidant wnameely applied to polyethylene, polypropylene, polyoxymethylene, ABS resin, PS resin, PVC, engineering plastics, binding agent, rubber, petroleum etc. for product polymerization. Application Antioxidant 168 is a kind of phosphite ester antioxidant as processing stabilizer, used for polypropylene, polyethylene, and adhesives. The amount to be used may be 0.1%~1.0% depending on the substrate, processing conditions, and requirements of the end application. Blends with hindered phenols are particularly effective.In addition, they use combination with light stabilizers when need. General Description Tris(2,4-di-tert-butylphenyl) phosphite is a triaryl based phosphite that can be used in catalysis and metallation. Its characteristic to undergo metallation reaction and provide a cost effective synthetic processes allows it to be useful in biaryl coupling reactions. Safety Antioxidant 168 is approved for indirect food contact applications. Properties and Applications TEST ITEMS SPECIFICATION APPEARANCE WHITE INCOMPACT POWDER CONTENT 99.0% min MELTING RANGE 183-187 °C VOLATILE 0.3% max SOLUBILITY 2g/20ml TOLUENE CLEAR FREE 2,4-DITERT-BUTYPHENOL 0.2% max (wt) TRANSMITTANCE 98% min 425nm 98% min 500nm ACID VALUE,mg KOH/g 0.3% max HYDROLYSIS TIME (90°C WATER ） 14 h min         SOLUBILITY 1% ACETONE 30% TOLUENE 36% CHLOROFORM 4% ETHYL ACETATE 11% n-HEXANE 0.1% ETHANOL 36% DICHLOROETHANE 6% max PHENYLETHYLENE 0.01% max WATER   Antioxidant 168 Preparation Products And Raw materials Raw materials Ethanol-->Xylene-->Phosphorus trichloride-->Phenol-->2,4-Di-tert-butylphenol Preparation Products Complex antioxidant