China Original Largest Manufacturer sales L(+)-Ornithine hydrochloride CAS 3184-13-2 CAS NO.3184-13-2

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L(+)-Ornithine hydrochloride Basic information Product Name: L(+)-Ornithine hydrochloride Synonyms: L-ORNITHINE HYDROCHLORIDE SALT;L-(+)-ORNITHINE MONOHYDROCHLORIDE;L-ORNITHINE MONOHYDROCHLORIDE;L-ORNITHINE-OH HCL;L-ORNITHINE-OH HYDROCHLORIDE;L-ORN HCL;L-ORNITHINE HCL;L(+)-ORNITHINE HYDROCHLORIDE CAS: 3184-13-2 MF: C5H13ClN2O2 MW: 168.62 EINECS: 221-678-6 Product Categories: amino;Amino hydrochloride;alpha-Amino Acids;Amino Acids;Biochemistry;non-Proteinorganic Amino Acids;Amino Acid Derivatives;Ornithine [Org];Amino Acids and Derivatives;L-Amino Acids;Amino Acids & Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals Mol File: 3184-13-2.mol   L(+)-Ornithine hydrochloride Chemical Properties Melting point  245 °C (dec.)(lit.) alpha  24 º (c=4, 6N HCl) density  1.57 refractive index  24 ° (C=4, 6mol/L HCl) FEMA  4190 | L-ORNITHINE MONOCHLOROHYDRATE/ORNITHINE storage temp.  Keep in dark place,Inert atmosphere,Room temperature solubility  H2O: 100 mg/mL form  Powder color  White PH 5.0-6.0 (25℃, 1M in H2O) optical activity [α]20/D +23.0±0.5°, c = 5% in 5 M HCl Water Solubility  Soluble in water (543 mg/ml at 20°C), and alcohol. λmax λ: 260 nm Amax: 0.06 λ: 280 nm Amax: 0.06 Merck  14,6874 JECFA Number 2120 BRN  3625847 Stability: Stable. InChIKey GGTYBZJRPHEQDG-WCCKRBBISA-N CAS DataBase Reference 3184-13-2(CAS DataBase Reference) EPA Substance Registry System L-Ornithine, monohydrochloride (3184-13-2)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38-36 Safety Statements  24/25-37/39-26 WGK Germany  3 RTECS  RM2985000 F  3-10 TSCA  Yes HS Code  29224995 Toxicity LD50 orl-rat: 10 g/kg JPMSAE 62,49,73 MSDS Information Provider Language L(+)-2,5-Diaminopentanoic acid hydrochloride English SigmaAldrich English ACROS English ALFA English   L(+)-Ornithine hydrochloride Usage And Synthesis Chemical Properties L(+)-Ornithine hydrochloride is white crystalline powder Chemical Properties White powder; mild green bark aroma. Uses Non-essential amino acid for human development but is required intermediate in arginine biosynthesis. Found in virtually all vertebrate tissues as well as incorporated into proteins, such as tyrocidine. Isolation from chicken excreta. Uses L(+)-Ornithine hydrochloride is a non-essential amino acid for human development but is required intermediate in arginine biosynthesis. L(+)-Ornithine hydrochloride is found in virtually all vertebrate tissues as well as incorporated into proteins, such as tyrocidine. Isolation from chicken excreta. Uses L(+)-Ornithine hydrochloride is a nonprotein amino acid used in the biosynthesis of L-arginine, L-proline and polyamines. Aroma threshold values Low strength odor, green type. Taste threshold values Very mild sweet taste at 500.00 ppm in water. General Description L-Ornithine is the functional metabolite of L-arginine. Biochem/physiol Actions L-ornithine acts as a precursor for polyamines. It may modulate the intake of food as an acute satiety signal in the neonatal chick brain. Safety Profile Mildly toxic by ingestion. When heated to decomposition it emits very toxic fumes of NOx and HCl. Purification Methods Likely impurities are citrulline, arginine and D-ornithine. Crystallise the monohydrochloride from water by adding 4volumes of EtOH and dry it in a vacuum desiccator over fused CaCl2. [Rivard Biochemical Preparations 3 98 1955.] The dihydrochloride [6211-16-1] has m 202-203o and [ ] D +18.4o (c 2.3, 6N HCl) after recrystallisation from MeOH/Et2O [Zaoral & Rudinger Collect Czech Chem Commun 24 2009 1959]. [Beilstein 4 IV 2644.]   L(+)-Ornithine hydrochloride Preparation Products And Raw materials Raw materials Butanoic acid, 4-cyano-2-[(diphenylmethylene)amino]-, 1,1-dimethylethyl ester, (2S)--->Butanoic acid, 2-amino-4-cyano-, 1,1-dimethylethyl ester, (2S)- (9CI)-->L-Ornithine, 1,1-dimethylethyl ester Preparation Products 3-Methoxy-2-Piperidone-->(2S)-5-amino-2-(tert-butoxycarbonylamino)-pentanoic acid tert-butyl ester-->3-hydroxypiperidin-2-one-->4-aminobutyronitrile-->(S)-3-aminopiperidin-2-one Hydrochloride

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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L(+)-Ornithine hydrochloride Basic information Product Name: L(+)-Ornithine hydrochloride Synonyms: L-ORNITHINE HYDROCHLORIDE SALT;L-(+)-ORNITHINE MONOHYDROCHLORIDE;L-ORNITHINE MONOHYDROCHLORIDE;L-ORNITHINE-OH HCL;L-ORNITHINE-OH HYDROCHLORIDE;L-ORN HCL;L-ORNITHINE HCL;L(+)-ORNITHINE HYDROCHLORIDE CAS: 3184-13-2 MF: C5H13ClN2O2 MW: 168.62 EINECS: 221-678-6 Product Categories: amino;Amino hydrochloride;alpha-Amino Acids;Amino Acids;Biochemistry;non-Proteinorganic Amino Acids;Amino Acid Derivatives;Ornithine [Org];Amino Acids and Derivatives;L-Amino Acids;Amino Acids & Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals Mol File: 3184-13-2.mol   L(+)-Ornithine hydrochloride Chemical Properties Melting point  245 °C (dec.)(lit.) alpha  24 º (c=4, 6N HCl) density  1.57 refractive index  24 ° (C=4, 6mol/L HCl) FEMA  4190 | L-ORNITHINE MONOCHLOROHYDRATE/ORNITHINE storage temp.  Keep in dark place,Inert atmosphere,Room temperature solubility  H2O: 100 mg/mL form  Powder color  White PH 5.0-6.0 (25℃, 1M in H2O) optical activity [α]20/D +23.0±0.5°, c = 5% in 5 M HCl Water Solubility  Soluble in water (543 mg/ml at 20°C), and alcohol. λmax λ: 260 nm Amax: 0.06 λ: 280 nm Amax: 0.06 Merck  14,6874 JECFA Number 2120 BRN  3625847 Stability: Stable. InChIKey GGTYBZJRPHEQDG-WCCKRBBISA-N CAS DataBase Reference 3184-13-2(CAS DataBase Reference) EPA Substance Registry System L-Ornithine, monohydrochloride (3184-13-2)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38-36 Safety Statements  24/25-37/39-26 WGK Germany  3 RTECS  RM2985000 F  3-10 TSCA  Yes HS Code  29224995 Toxicity LD50 orl-rat: 10 g/kg JPMSAE 62,49,73 MSDS Information Provider Language L(+)-2,5-Diaminopentanoic acid hydrochloride English SigmaAldrich English ACROS English ALFA English   L(+)-Ornithine hydrochloride Usage And Synthesis Chemical Properties L(+)-Ornithine hydrochloride is white crystalline powder Chemical Properties White powder; mild green bark aroma. Uses Non-essential amino acid for human development but is required intermediate in arginine biosynthesis. Found in virtually all vertebrate tissues as well as incorporated into proteins, such as tyrocidine. Isolation from chicken excreta. Uses L(+)-Ornithine hydrochloride is a non-essential amino acid for human development but is required intermediate in arginine biosynthesis. L(+)-Ornithine hydrochloride is found in virtually all vertebrate tissues as well as incorporated into proteins, such as tyrocidine. Isolation from chicken excreta. Uses L(+)-Ornithine hydrochloride is a nonprotein amino acid used in the biosynthesis of L-arginine, L-proline and polyamines. Aroma threshold values Low strength odor, green type. Taste threshold values Very mild sweet taste at 500.00 ppm in water. General Description L-Ornithine is the functional metabolite of L-arginine. Biochem/physiol Actions L-ornithine acts as a precursor for polyamines. It may modulate the intake of food as an acute satiety signal in the neonatal chick brain. Safety Profile Mildly toxic by ingestion. When heated to decomposition it emits very toxic fumes of NOx and HCl. Purification Methods Likely impurities are citrulline, arginine and D-ornithine. Crystallise the monohydrochloride from water by adding 4volumes of EtOH and dry it in a vacuum desiccator over fused CaCl2. [Rivard Biochemical Preparations 3 98 1955.] The dihydrochloride [6211-16-1] has m 202-203o and [ ] D +18.4o (c 2.3, 6N HCl) after recrystallisation from MeOH/Et2O [Zaoral & Rudinger Collect Czech Chem Commun 24 2009 1959]. [Beilstein 4 IV 2644.]   L(+)-Ornithine hydrochloride Preparation Products And Raw materials Raw materials Butanoic acid, 4-cyano-2-[(diphenylmethylene)amino]-, 1,1-dimethylethyl ester, (2S)--->Butanoic acid, 2-amino-4-cyano-, 1,1-dimethylethyl ester, (2S)- (9CI)-->L-Ornithine, 1,1-dimethylethyl ester Preparation Products 3-Methoxy-2-Piperidone-->(2S)-5-amino-2-(tert-butoxycarbonylamino)-pentanoic acid tert-butyl ester-->3-hydroxypiperidin-2-one-->4-aminobutyronitrile-->(S)-3-aminopiperidin-2-one Hydrochloride