China Largest Manufacturer factory sales D-Glucurone CAS 32449-92-6 CAS NO.32449-92-6

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D-Glucurone Basic information Product Name: D-Glucurone Synonyms: D-Glucurono-6,3-lactone D-Glucuronic Acid Lactone D(+)-Glucurono-3,6-lactone D-(+)-Glucuronic acid γ-lactone Glucuronolactone;D-(+)-Glucuronolactone for synthesis;b-d-anhydroglucuronate;d-glucurono-gamma-lactone;D-Glucuronic acid, g-lactone;D-Glucorono-6,3-lactone;Glucorolactone;D(+)-Glucurono-3,6-lactone SynonyM: D-Glucurone CAS: 32449-92-6 MF: C6H8O6 MW: 176.12 EINECS: 251-053-3 Product Categories: Biochemistry;Glucose;Miscellaneous Natural Products;Sugar Acids;Sugars;Dextrins、Sugar & Carbohydrates;Carbohydrates & Derivatives;API;carbohydrate;bulk drug material， food addictive;Halogenated Heterocycles Mol File: 32449-92-6.mol   D-Glucurone Chemical Properties Melting point  172-175 °C (lit.) alpha  19 º (c=10, H2O) Boiling point  227.71°C (rough estimate) density  1,76 g/cm3 refractive index  18.5 ° (C=5, H2O) storage temp.  Store below +30°C. solubility  water: soluble25mg/mL, clear, colorless form  Crystals or Crystalline Powder pka 11.96±0.60(Predicted) color  White optical activity [α]24/D +18.8°, c = 8 in H2O Water Solubility  SOLUBLE Merck  14,4467 BRN  83595 InChIKey OGLCQHRZUSEXNB-IEPORWDDSA-N CAS DataBase Reference 32449-92-6(CAS DataBase Reference) EPA Substance Registry System D-Glucuronolactone (32449-92-6)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  24/25-36-26 WGK Germany  2 RTECS  LZ8930000 TSCA  Yes HS Code  29322980 MSDS Information Provider Language D-Glucurone English SigmaAldrich English ACROS English ALFA English   D-Glucurone Usage And Synthesis Chemical Properties white crystals or crystalline powder Uses D-Glucurone is a glucuronic acid derivative. It is used for treating canine hepatitis. Uses D-Glucurono-6,3-lactone is a glucuronic acid derivative studied for its effectiveness against canine hepatitis. It is utilized in the studies such as starting regent in the synthesis of 2,3,4,-tris(tert.-butyldimethysilyl) glucuronic acid trichloroethylester, required for the preparation of 1-O-acyl glucuronide of the anti-inflammatory drug ML-3000, synthesis of optically active glucopyranoses, synthesis of long-chain alkyl glucofuranosides. Definition The γ-lactone of glucuronic acid. Found in plant gums and animal connective tissues. General Description D-(+)-Glucuronic acid γ-lactone (Glucourono-γ-lactone, Glucurone or Glycurone) is a carbohydrate derivative. It converted into L-ascorbic acid in animals and human body. Its molecule contains two five-membered rings. Its crystal structure has been studied. Purification Methods Dissolve the lactone or mixture of lactone and acid in H2O and concentrate on a steam bath until crystallisation begins. Cool rapidly to room temperature wih stirring. After 2hours the product is filtered off, washed with cold EtOH and dried to m 174-175o and [] D +19.8o (c 5.2, H2O). The amount of free acid can be obtained by titration of an ice-cold aqueous solution with standard alkali. It can be recrystallised from EtOH, EtOH/H2O or MeOH, and the highest recorded m is 180o. [Stacey J Chem Soc 1529 1939, Mehltretter et al. J Am Chem Soc 73 2424 1951, Beilstein 18 III/IV 3055, 18/5 V 33.]   D-Glucurone Preparation Products And Raw materials Raw materials DOWEX MAC-3 ION EXCHANGE RESIN-->D-Glucuronic acid

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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D-Glucurone Basic information Product Name: D-Glucurone Synonyms: D-Glucurono-6,3-lactone D-Glucuronic Acid Lactone D(+)-Glucurono-3,6-lactone D-(+)-Glucuronic acid γ-lactone Glucuronolactone;D-(+)-Glucuronolactone for synthesis;b-d-anhydroglucuronate;d-glucurono-gamma-lactone;D-Glucuronic acid, g-lactone;D-Glucorono-6,3-lactone;Glucorolactone;D(+)-Glucurono-3,6-lactone SynonyM: D-Glucurone CAS: 32449-92-6 MF: C6H8O6 MW: 176.12 EINECS: 251-053-3 Product Categories: Biochemistry;Glucose;Miscellaneous Natural Products;Sugar Acids;Sugars;Dextrins、Sugar & Carbohydrates;Carbohydrates & Derivatives;API;carbohydrate;bulk drug material， food addictive;Halogenated Heterocycles Mol File: 32449-92-6.mol   D-Glucurone Chemical Properties Melting point  172-175 °C (lit.) alpha  19 º (c=10, H2O) Boiling point  227.71°C (rough estimate) density  1,76 g/cm3 refractive index  18.5 ° (C=5, H2O) storage temp.  Store below +30°C. solubility  water: soluble25mg/mL, clear, colorless form  Crystals or Crystalline Powder pka 11.96±0.60(Predicted) color  White optical activity [α]24/D +18.8°, c = 8 in H2O Water Solubility  SOLUBLE Merck  14,4467 BRN  83595 InChIKey OGLCQHRZUSEXNB-IEPORWDDSA-N CAS DataBase Reference 32449-92-6(CAS DataBase Reference) EPA Substance Registry System D-Glucuronolactone (32449-92-6)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  24/25-36-26 WGK Germany  2 RTECS  LZ8930000 TSCA  Yes HS Code  29322980 MSDS Information Provider Language D-Glucurone English SigmaAldrich English ACROS English ALFA English   D-Glucurone Usage And Synthesis Chemical Properties white crystals or crystalline powder Uses D-Glucurone is a glucuronic acid derivative. It is used for treating canine hepatitis. Uses D-Glucurono-6,3-lactone is a glucuronic acid derivative studied for its effectiveness against canine hepatitis. It is utilized in the studies such as starting regent in the synthesis of 2,3,4,-tris(tert.-butyldimethysilyl) glucuronic acid trichloroethylester, required for the preparation of 1-O-acyl glucuronide of the anti-inflammatory drug ML-3000, synthesis of optically active glucopyranoses, synthesis of long-chain alkyl glucofuranosides. Definition The γ-lactone of glucuronic acid. Found in plant gums and animal connective tissues. General Description D-(+)-Glucuronic acid γ-lactone (Glucourono-γ-lactone, Glucurone or Glycurone) is a carbohydrate derivative. It converted into L-ascorbic acid in animals and human body. Its molecule contains two five-membered rings. Its crystal structure has been studied. Purification Methods Dissolve the lactone or mixture of lactone and acid in H2O and concentrate on a steam bath until crystallisation begins. Cool rapidly to room temperature wih stirring. After 2hours the product is filtered off, washed with cold EtOH and dried to m 174-175o and [] D +19.8o (c 5.2, H2O). The amount of free acid can be obtained by titration of an ice-cold aqueous solution with standard alkali. It can be recrystallised from EtOH, EtOH/H2O or MeOH, and the highest recorded m is 180o. [Stacey J Chem Soc 1529 1939, Mehltretter et al. J Am Chem Soc 73 2424 1951, Beilstein 18 III/IV 3055, 18/5 V 33.]   D-Glucurone Preparation Products And Raw materials Raw materials DOWEX MAC-3 ION EXCHANGE RESIN-->D-Glucuronic acid