China Largest Manufacturer factory sales L-Cycloserine CAS 339-72-0 CAS NO.339-72-0

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L-CYCLOSERINE Basic information Product Name: L-CYCLOSERINE Synonyms: (S)-4-Aminoisoxazolidin-3-one;Levocycloserine;L-Cycloserine,99%;L-Cycloserine,(S)-4-Amino-3-isoxazolidone;cycloserinr;102.09;Cycloserine Impurity 4 (L-Cycloserine);Cycloserine Impurity 4 CAS: 339-72-0 MF: C3H6N2O2 MW: 102.09 EINECS: 206-427-0 Product Categories: NOVASTAT-W;VARIOUSAMINE Mol File: 339-72-0.mol   L-CYCLOSERINE Chemical Properties Melting point  147 °C Boiling point  191.38°C (rough estimate) density  1.278 refractive index  1.5110 (estimate) storage temp.  Keep in dark place,Sealed in dry,Store in freezer, under -20°C solubility  H2O: soluble50mg/mg protein form  White to off-white powder. pka 14.36±0.40(Predicted) color  White to Off-White BRN  80799 CAS DataBase Reference 339-72-0(CAS DataBase Reference)   Safety Information Hazard Codes  Xn Risk Statements  5-20 Safety Statements  38-36/37 WGK Germany  2 RTECS  NY2976000 F  10 MSDS Information Provider Language SigmaAldrich English ACROS English   L-CYCLOSERINE Usage And Synthesis Chemical Properties WHITE GRANULAR POWDER Uses antibacterial, coccidiostat Uses L-Cycloserine is an irreversible inhibitor of 3-ketodihydrosphingosine synthetase. Definition ChEBI: A 4-amino-1,2-oxazolidin-3-one that has S configuration. An antibiotic isolated from Erwinia uredovora. Biochem/physiol Actions L-cycloserine is a potent inhibitor of serine palmitoyltransferase, the first step of sphingolipid synthesis. Purification Methods Purify cycloserine by recrystallisation from aqueous EtOH or MeOH or aqueous NH3/EtOH or isoPrOH. Also recrystallise it from aqueous ammoniacal solution at pH 10.5 (100mg/mL) by diluting with 5 volumes of isopropanol and then adjusting to pH 6 with acetic acid. An aqueous solution, buffered to pH 10 with Na2CO3, can be stored in a refrigerator for 1week without decomposition. UV: max at 226nm (A1cm 1% 4.02). The tartrate salt has m 165-166o (dec), 166-168o (dec), and [] D 24 -41o (c 0.7, H2O). [Stammer et al. J Am Chem Soc 79 3236 1959, UV: Kuehl J Am Chem Soc 77 2344 1955, Beilstein 27 III/IV 5549.]   L-CYCLOSERINE Preparation Products And Raw materials Raw materials H-BETA-CHLORO-ALA-NHOH-->BETA-CHLORO-D-ALANINE HYDROCHLORIDE

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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L-CYCLOSERINE Basic information Product Name: L-CYCLOSERINE Synonyms: (S)-4-Aminoisoxazolidin-3-one;Levocycloserine;L-Cycloserine,99%;L-Cycloserine,(S)-4-Amino-3-isoxazolidone;cycloserinr;102.09;Cycloserine Impurity 4 (L-Cycloserine);Cycloserine Impurity 4 CAS: 339-72-0 MF: C3H6N2O2 MW: 102.09 EINECS: 206-427-0 Product Categories: NOVASTAT-W;VARIOUSAMINE Mol File: 339-72-0.mol   L-CYCLOSERINE Chemical Properties Melting point  147 °C Boiling point  191.38°C (rough estimate) density  1.278 refractive index  1.5110 (estimate) storage temp.  Keep in dark place,Sealed in dry,Store in freezer, under -20°C solubility  H2O: soluble50mg/mg protein form  White to off-white powder. pka 14.36±0.40(Predicted) color  White to Off-White BRN  80799 CAS DataBase Reference 339-72-0(CAS DataBase Reference)   Safety Information Hazard Codes  Xn Risk Statements  5-20 Safety Statements  38-36/37 WGK Germany  2 RTECS  NY2976000 F  10 MSDS Information Provider Language SigmaAldrich English ACROS English   L-CYCLOSERINE Usage And Synthesis Chemical Properties WHITE GRANULAR POWDER Uses antibacterial, coccidiostat Uses L-Cycloserine is an irreversible inhibitor of 3-ketodihydrosphingosine synthetase. Definition ChEBI: A 4-amino-1,2-oxazolidin-3-one that has S configuration. An antibiotic isolated from Erwinia uredovora. Biochem/physiol Actions L-cycloserine is a potent inhibitor of serine palmitoyltransferase, the first step of sphingolipid synthesis. Purification Methods Purify cycloserine by recrystallisation from aqueous EtOH or MeOH or aqueous NH3/EtOH or isoPrOH. Also recrystallise it from aqueous ammoniacal solution at pH 10.5 (100mg/mL) by diluting with 5 volumes of isopropanol and then adjusting to pH 6 with acetic acid. An aqueous solution, buffered to pH 10 with Na2CO3, can be stored in a refrigerator for 1week without decomposition. UV: max at 226nm (A1cm 1% 4.02). The tartrate salt has m 165-166o (dec), 166-168o (dec), and [] D 24 -41o (c 0.7, H2O). [Stammer et al. J Am Chem Soc 79 3236 1959, UV: Kuehl J Am Chem Soc 77 2344 1955, Beilstein 27 III/IV 5549.]   L-CYCLOSERINE Preparation Products And Raw materials Raw materials H-BETA-CHLORO-ALA-NHOH-->BETA-CHLORO-D-ALANINE HYDROCHLORIDE