China Biggest Manufacturer factory sales ISOPRINOSINE CAS 36703-88-5 CAS NO.36703-88-5

                                PRODUCT DETAILS                           

ISOPRINOSINE Basic information Description Sources Product Name: ISOPRINOSINE Synonyms: ISOPRINOSINE;)(1:3);aviral;delimmun;imunovir;inosine,compd.with1-(dimethylamino)-2-propanol4-(acetylamino)benzoate(salt;inosinepranobex;inosiplex CAS: 36703-88-5 MF: C24H34N6O9 MW: 550.57 EINECS: 253-162-1 Product Categories:   Mol File: 36703-88-5.mol   ISOPRINOSINE Chemical Properties Melting point  140-142°C storage temp.  Inert atmosphere,Room Temperature solubility  DMSO (Slightly, Heated), Methanol (Slightly, Heated, Sonicated), Water (Slightly form  Solid color  White to Off-White Merck  14,4976   Safety Information Toxicity LD50 in mice and rats (mg/kg): >4000 orally and i.p. (Gordon) MSDS Information   ISOPRINOSINE Usage And Synthesis Description ISOPRINOSINE (also known as inosine pranobex) an antiviral drug combing of inosine and dimepranol acedoben (a salt of acetamidobenzoic acid and dimethylaminoisopropanol) in a ratio of 1 to 3. It is mainly used for treating the rare measles complication subacute sclerosing panencephalitis in conjunction with intrathecal interferon therapy1,2. In UK, it is also indicated for mucocutaneous infections due to herpes simplex virus (type 1 and type 2) and for treatment of genital warts as adjunctive therapy to podophyllin or carbon dioxide laser1. It also has certain efficacy in the treatment of AIDS and some other acquired immunodeficiency such as aged patients, cancer patients, severely burned patients, ill patients, and surgery patients3. Preclinical studies have demonstrated that isoprinosine can inhibit the growth of both DNA and RNA viruses as well as potentiate cell-mediated immune response both in vitro and in vivo4,5. Sources # Waldman, R. H., and R. Ganguly. "Therapeutic efficacy of inosiplex (Isoprinosine) in rhinovirus infection. " Annals of the New York Academy of Sciences 284.1(1977):153–160. # # # Chemical Properties White Solid Uses Isoprinosine Uses Isoprinosine is a new combination of active substances for the treatment of chronic systemic diseases such as cancer. Isoprinosine is an immunomodulator; antiviral. The ratio is between 1: 2 : 2 to 1 : 3 : 3 Clinical Use Treatment of mucocutaneous herpes simplex, genital warts, subacute sclerosing panencephalitis Drug interactions Potentially hazardous interactions with other drugs None known Metabolism Hepatically metabolised. The major excretion product of the inosine moiety is uric acid, while the p-acetamidobenzoic acid and N,N-dimethylamino- 2-propanol components are excreted in the urine as glucuronidated and oxidised products, respectively, as well as being excreted unchanged   ISOPRINOSINE Preparation Products And Raw materials

                                Group profiles

Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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                                                       Product information

ISOPRINOSINE Basic information Description Sources Product Name: ISOPRINOSINE Synonyms: ISOPRINOSINE;)(1:3);aviral;delimmun;imunovir;inosine,compd.with1-(dimethylamino)-2-propanol4-(acetylamino)benzoate(salt;inosinepranobex;inosiplex CAS: 36703-88-5 MF: C24H34N6O9 MW: 550.57 EINECS: 253-162-1 Product Categories:   Mol File: 36703-88-5.mol   ISOPRINOSINE Chemical Properties Melting point  140-142°C storage temp.  Inert atmosphere,Room Temperature solubility  DMSO (Slightly, Heated), Methanol (Slightly, Heated, Sonicated), Water (Slightly form  Solid color  White to Off-White Merck  14,4976   Safety Information Toxicity LD50 in mice and rats (mg/kg): >4000 orally and i.p. (Gordon) MSDS Information   ISOPRINOSINE Usage And Synthesis Description ISOPRINOSINE (also known as inosine pranobex) an antiviral drug combing of inosine and dimepranol acedoben (a salt of acetamidobenzoic acid and dimethylaminoisopropanol) in a ratio of 1 to 3. It is mainly used for treating the rare measles complication subacute sclerosing panencephalitis in conjunction with intrathecal interferon therapy1,2. In UK, it is also indicated for mucocutaneous infections due to herpes simplex virus (type 1 and type 2) and for treatment of genital warts as adjunctive therapy to podophyllin or carbon dioxide laser1. It also has certain efficacy in the treatment of AIDS and some other acquired immunodeficiency such as aged patients, cancer patients, severely burned patients, ill patients, and surgery patients3. Preclinical studies have demonstrated that isoprinosine can inhibit the growth of both DNA and RNA viruses as well as potentiate cell-mediated immune response both in vitro and in vivo4,5. Sources # Waldman, R. H., and R. Ganguly. "Therapeutic efficacy of inosiplex (Isoprinosine) in rhinovirus infection. " Annals of the New York Academy of Sciences 284.1(1977):153–160. # # # Chemical Properties White Solid Uses Isoprinosine Uses Isoprinosine is a new combination of active substances for the treatment of chronic systemic diseases such as cancer. Isoprinosine is an immunomodulator; antiviral. The ratio is between 1: 2 : 2 to 1 : 3 : 3 Clinical Use Treatment of mucocutaneous herpes simplex, genital warts, subacute sclerosing panencephalitis Drug interactions Potentially hazardous interactions with other drugs None known Metabolism Hepatically metabolised. The major excretion product of the inosine moiety is uric acid, while the p-acetamidobenzoic acid and N,N-dimethylamino- 2-propanol components are excreted in the urine as glucuronidated and oxidised products, respectively, as well as being excreted unchanged   ISOPRINOSINE Preparation Products And Raw materials