China Biggest Factory Manufacturer Supply N-Ethyl-p-menthane-3-carboxamide/Cooling taste agent ws-23 CAS 39711-79-0 CAS NO.39711-79-0

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N-Ethyl-p-menthane-3-carboxamide Basic information Product Name: N-Ethyl-p-menthane-3-carboxamide Synonyms: Cooling taste agent ws-23;N,2,3-trimethyl-2isopropl butanamide;N-Ethyl-2-(isopropyl)-5-methylcyclohexanecarboxamide N-Ethyl-5-methyl-2-(1-methylethyl)-cyclohexane-carboxamide Ethyl menthane carboxamide Framidice 3 Menthol Carboxamide WS-3;FEMA 3455;WS-3;Menthol Carboxamide;N-Ethyl-PARA-Menthan-3-Carboxamide;TRPM8 antagonist WS-3 CAS: 39711-79-0 MF: C13H25NO MW: 211.34 EINECS: 254-599-0 Product Categories:   Mol File: 39711-79-0.mol   N-Ethyl-p-menthane-3-carboxamide Chemical Properties Melting point  87-102 °C Boiling point  351.04°C (rough estimate) alpha  D -49 to -54° density  0.9305 (rough estimate) refractive index  1.4410 (estimate) FEMA  3455 | N-ETHYL-2-ISOPROPYL-5-METHYLCYCLOHEXANE CARBOXAMIDE storage temp.  Sealed in dry,Room Temperature pka 16.27±0.60(Predicted) Water Solubility  insoluble JECFA Number 1601 Merck  14,3825 InChIKey VUNOFAIHSALQQH-UHFFFAOYSA-N CAS DataBase Reference 39711-79-0(CAS DataBase Reference) EPA Substance Registry System Cyclohexanecarboxamide, N-ethyl-5-methyl-2-(1-methylethyl)- (39711-79-0)   Safety Information Hazard Codes  Xi,Xn Risk Statements  36-41-22 Safety Statements  39-26 WGK Germany  2 HS Code  29242990 Toxicity LD50 in mice, rats (g/kg): 5.3, 2.9 orally (Parrish) MSDS Information Provider Language N-Ethyl-p-menthane-3-carboxamide English ACROS English   N-Ethyl-p-menthane-3-carboxamide Usage And Synthesis Chemical Properties white crystalline powder Chemical Properties N-ethyl-p-menthane-3-carboxamide is an odorless white, crystalline solid. The compound has a strong and clear physiological cooling effect and is used mainly in oral care products. Chemical Properties Slight menthol-like cooling effect aroma Uses Physiological coolant in foods, beverages, toiletries, cosmetics and pharmaceuticals. Uses WS 3 is a selective transient receptor potential melastatin-8 ligand. Aroma threshold values Aroma characteristics at 1.0%. Virtually odorless Taste threshold values Taste characteristics at 10 to 100 ppm. Intense lingering cooling. The cooling sensation builds slow but steadily and grows to a lingering cooling mouthfeel with a slightly camphoraceous and minty character. Trade name Winsense WS-3 (Renessenz) Biological Activity Cooling agent that is an agonist at TRPM8 receptors (EC 50 = 3.7 μ M).   N-Ethyl-p-menthane-3-carboxamide Preparation Products And Raw materials

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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N-Ethyl-p-menthane-3-carboxamide Basic information Product Name: N-Ethyl-p-menthane-3-carboxamide Synonyms: Cooling taste agent ws-23;N,2,3-trimethyl-2isopropl butanamide;N-Ethyl-2-(isopropyl)-5-methylcyclohexanecarboxamide N-Ethyl-5-methyl-2-(1-methylethyl)-cyclohexane-carboxamide Ethyl menthane carboxamide Framidice 3 Menthol Carboxamide WS-3;FEMA 3455;WS-3;Menthol Carboxamide;N-Ethyl-PARA-Menthan-3-Carboxamide;TRPM8 antagonist WS-3 CAS: 39711-79-0 MF: C13H25NO MW: 211.34 EINECS: 254-599-0 Product Categories:   Mol File: 39711-79-0.mol   N-Ethyl-p-menthane-3-carboxamide Chemical Properties Melting point  87-102 °C Boiling point  351.04°C (rough estimate) alpha  D -49 to -54° density  0.9305 (rough estimate) refractive index  1.4410 (estimate) FEMA  3455 | N-ETHYL-2-ISOPROPYL-5-METHYLCYCLOHEXANE CARBOXAMIDE storage temp.  Sealed in dry,Room Temperature pka 16.27±0.60(Predicted) Water Solubility  insoluble JECFA Number 1601 Merck  14,3825 InChIKey VUNOFAIHSALQQH-UHFFFAOYSA-N CAS DataBase Reference 39711-79-0(CAS DataBase Reference) EPA Substance Registry System Cyclohexanecarboxamide, N-ethyl-5-methyl-2-(1-methylethyl)- (39711-79-0)   Safety Information Hazard Codes  Xi,Xn Risk Statements  36-41-22 Safety Statements  39-26 WGK Germany  2 HS Code  29242990 Toxicity LD50 in mice, rats (g/kg): 5.3, 2.9 orally (Parrish) MSDS Information Provider Language N-Ethyl-p-menthane-3-carboxamide English ACROS English   N-Ethyl-p-menthane-3-carboxamide Usage And Synthesis Chemical Properties white crystalline powder Chemical Properties N-ethyl-p-menthane-3-carboxamide is an odorless white, crystalline solid. The compound has a strong and clear physiological cooling effect and is used mainly in oral care products. Chemical Properties Slight menthol-like cooling effect aroma Uses Physiological coolant in foods, beverages, toiletries, cosmetics and pharmaceuticals. Uses WS 3 is a selective transient receptor potential melastatin-8 ligand. Aroma threshold values Aroma characteristics at 1.0%. Virtually odorless Taste threshold values Taste characteristics at 10 to 100 ppm. Intense lingering cooling. The cooling sensation builds slow but steadily and grows to a lingering cooling mouthfeel with a slightly camphoraceous and minty character. Trade name Winsense WS-3 (Renessenz) Biological Activity Cooling agent that is an agonist at TRPM8 receptors (EC 50 = 3.7 μ M).   N-Ethyl-p-menthane-3-carboxamide Preparation Products And Raw materials